메뉴 건너뛰기




Volumn 28, Issue 4, 2005, Pages 281-297

Sequencing antiretroviral drugs for long-lasting suppression of HIV replication

Author keywords

Antiretroviral sequencing; Drug resistance; HAART; HIV 1; Mitochondrial toxicity

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

EID: 29244451381     PISSN: 11217138     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (10)

References (87)
  • 1
    • 0032506055 scopus 로고    scopus 로고
    • Phenotypic mechanism of HIV-1 resistance to 3′-azido-3′- deoxythymidine (AZT): Increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase
    • ARION, D., KAUSHIK, N., MCCORMICK, S., BORKOW, G., AND M. A. PARNIAK. (1998). Phenotypic mechanism of HIV-1 resistance to 3′-azido-3′- deoxythymidine (AZT): increased polymerization processivity and enhanced sensitivity to pyrophosphate of the mutant viral reverse transcriptase. Biochemistry, 37, 15908-15917.
    • (1998) Biochemistry , vol.37 , pp. 15908-15917
    • Arion, D.1    Kaushik, N.2    McCormick, S.3    Borkow, G.4    Parniak, M.A.5
  • 3
    • 0029757751 scopus 로고    scopus 로고
    • Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme
    • BACK, N.K., NIJHUIS, M., KEULEN, W., BOUCHER, C.A., OUDE ESSINK, B.O., VAN KUILENBURG, A.B., VAN GENNIP, A.H., AND BERKHOUT, B. (1996). Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. EMBO J, 15, 4040-4049.
    • (1996) EMBO J , vol.15 , pp. 4040-4049
    • Back, N.K.1    Nijhuis, M.2    Keulen, W.3    Boucher, C.A.4    Oude Essink, B.O.5    Van Kuilenburg, A.B.6    Van Gennip, A.H.7    Berkhout, B.8
  • 4
    • 0036174438 scopus 로고    scopus 로고
    • Assessment of mitochondrial toxicity in human cells treated with tenofovir: Comparison with other nucleoside reverse transcriptase inhibitors
    • BIRKUS, G., HITCHCOCK, M.J., AND CIHLAR. T. (2002). Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors. Antimicrob. Agents Chemother, 46, 716-723.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 716-723
    • Birkus, G.1    Hitchcock, M.J.2    Cihlar, T.3
  • 6
    • 0037456351 scopus 로고    scopus 로고
    • Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection
    • BOZZETTE, S.A., AKE, C.F., TAM, H.K., CHANG S.W., AND LOUIS, T.A. (2003). Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection. N. Engl. J. Med, 348, 702-710.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 702-710
    • Bozzette, S.A.1    Ake, C.F.2    Tam, H.K.3    Chang, S.W.4    Louis, T.A.5
  • 7
    • 0042328301 scopus 로고    scopus 로고
    • Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals
    • BRAMBILLA, A.M., NOVATI, R., CALORI, G., MENEGHINI, E., VACCHINI, D., LUZI, L., CASTAGNA, A. AND LAZZARIN, A. (2003). Stavudine or indinavir-containing regimens are associated with an increased risk of diabetes mellitus in HIV-infected individuals. AIDS, 17, 1993-1995.
    • (2003) AIDS , vol.17 , pp. 1993-1995
    • Brambilla, A.M.1    Novati, R.2    Calori, G.3    Meneghini, E.4    Vacchini, D.5    Luzi, L.6    Castagna, A.7    Lazzarin, A.8
  • 8
    • 27444431816 scopus 로고    scopus 로고
    • Cumulative exposure to nucleoside analogue reverse transcriptase inhibitors is associated with insulin resistance markers in the Multicenter AIDS Cohort Study
    • BROWN, T.T., LI, X., COLE, S.R., KINGSLEY, L.A., PALELLA F.J., RIDDLER, S.A., CHMIEL, J.S., VISSCHER, B.R., MARGOLICK, J.B. AND DOBS, A.S. (2005). Cumulative exposure to nucleoside analogue reverse transcriptase inhibitors is associated with insulin resistance markers in the Multicenter AIDS Cohort Study. AIDS, 19, 1375-1383.
    • (2005) AIDS , vol.19 , pp. 1375-1383
    • Brown, T.T.1    Li, X.2    Cole, S.R.3    Kingsley, L.A.4    Palella, F.J.5    Riddler, S.A.6    Chmiel, J.S.7    Visscher, B.R.8    Margolick, J.B.9    Dobs, A.S.10
  • 10
    • 4344707647 scopus 로고    scopus 로고
    • The NIQ of lopinavir is predictive of a 48-week virological response in highly treatment-experienced HIV-1-infected subjects treated with a lopinavir/ritonavir-containing regimen
    • CASTAGNA, A., GIANOTTI, N., GALLI, L., DANISE, A., HASSON, H., BOERI, E., HOETELMANS, R., NAUWELAERS, D., AND LAZZARIN, A. (2004). The NIQ of lopinavir is predictive of a 48-week virological response in highly treatment-experienced HIV-1-infected subjects treated with a lopinavir/ritonavir-containing regimen. Antivir Ther, 9, 537-543.
    • (2004) Antivir. Ther. , vol.9 , pp. 537-543
    • Castagna, A.1    Gianotti, N.2    Galli, L.3    Danise, A.4    Hasson, H.5    Boeri, E.6    Hoetelmans, R.7    Nauwelaers, D.8    Lazzarin, A.9
  • 11
    • 1442355578 scopus 로고    scopus 로고
    • HIV drug resistance
    • CLAVEL, F. AND HANCE A.J. (2004). HIV drug resistance. N. Engl. J. Med., 350, 1023-1035.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 1023-1035
    • Clavel, F.1    Hance, A.J.2
  • 12
    • 2942596050 scopus 로고    scopus 로고
    • Clinical management of treatment-experienced, HIV-infected patients with the fusion inhibitor enfuvirtide: Consensus recommendations
    • CLOTET, B., RAFFI, F., COOPER, D., DELFRAISSY, J.F., LAZZARIN, A., MOYLE, G., ROCKSTROH, J., SORIANO, V., AND SCHAPIRO, J. (2004). Clinical management of treatment-experienced, HIV-infected patients with the fusion inhibitor enfuvirtide: consensus recommendations. AIDS 18, 1137-1146.
    • (2004) AIDS , vol.18 , pp. 1137-1146
    • Clotet, B.1    Raffi, F.2    Cooper, D.3    Delfraissy, J.F.4    Lazzarin, A.5    Moyle, G.6    Rockstroh, J.7    Soriano, V.8    Schapiro, J.9
  • 13
    • 2442657656 scopus 로고    scopus 로고
    • Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens
    • COLONNO, R., ROSE, R., MCLAREN, C., THIRY, A., PARKIN, N., AND FRIBORG, J. (2004). Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens. J. Infect. Dis., 189, 1802-1810.
    • (2004) J. Infect. Dis. , vol.189 , pp. 1802-1810
    • Colonno, R.1    Rose, R.2    McLaren, C.3    Thiry, A.4    Parkin, N.5    Friborg, J.6
  • 15
    • 0032990266 scopus 로고    scopus 로고
    • Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: Antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome
    • DEEKS, S.G., HELLMANN, N.S., GRANT, R.M., PARKIN, N.T., PETROPOULOS, C.J., BECKER, M., SYMONDS, W., CHESNEY, M., AND VOLBERDING, P.A. (1999). Novel four-drug salvage treatment regimens after failure of a human immunodeficiency virus type 1 protease inhibitor-containing regimen: antiviral activity and correlation of baseline phenotypic drug susceptibility with virologic outcome. J. Infect. Dis., 179, 1375-1381.
    • (1999) J. Infect. Dis. , vol.179 , pp. 1375-1381
    • Deeks, S.G.1    Hellmann, N.S.2    Grant, R.M.3    Parkin, N.T.4    Petropoulos, C.J.5    Becker, M.6    Symonds, W.7    Chesney, M.8    Volberding, P.A.9
  • 16
    • 0035292858 scopus 로고    scopus 로고
    • International perspectives on antiretroviral resistance. Nonnucleoside reverse transcriptase inhibitor resistance
    • DEEKS, S.G. (2001). International perspectives on antiretroviral resistance. Nonnucleoside reverse transcriptase inhibitor resistance. J. Acquir. Immune Defic. Syndr., 26, Suppl 1, S25-33.
    • (2001) J. Acquir. Immune Defic. Syndr. , vol.26 , Issue.1 SUPPL.
    • Deeks, S.G.1
  • 19
  • 20
    • 0035824745 scopus 로고    scopus 로고
    • Failure to maintain long-term adherence to highly active antiretroviral therapy: The role of lipodystrophy
    • DURAN, S., SAVES, M., SPIRE, B., CAILLETON, V., SOBEL, A., CARRIERI, P., SALMON, D. MOATTI, J.P., LEPORT, C., AND APROCO STUDY GROUP. (2001). Failure to maintain long-term adherence to highly active antiretroviral therapy: the role of lipodystrophy. AIDS 15, 2441-2444.
    • (2001) AIDS , vol.15 , pp. 2441-2444
    • Duran, S.1    Saves, M.2    Spire, B.3    Cailleton, V.4    Sobel, A.5    Carrieri, P.6    Salmon, D.7    Moatti, J.P.8    Leport, C.9
  • 22
    • 0033587620 scopus 로고    scopus 로고
    • Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase
    • FENG, J.Y., AND ANDERSON, K.S. (1999). Mechanistic studies examining the efficiency and fidelity of DNA synthesis by the 3TC-resistant mutant (184V) of HIV-1 reverse transcriptase. Biochemistry, 38, 9440-9448.
    • (1999) Biochemistry , vol.38 , pp. 9440-9448
    • Feng, J.Y.1    Anderson, K.S.2
  • 24
    • 0345455402 scopus 로고    scopus 로고
    • Early non-response to tenofovir DF (TDF) + abacavir (ABC) and lamivudine (3TC) in a randomized trial compared to efavirenz (EFV) + ABC and 3TC: ESS30009 unplanned interim analysis
    • Chicago, IL, September 14-17. Abstract H-1722a
    • GALLANT, J., RODRIGUEZ, A., AND WEINBERG, W. (2003). Early non-response to tenofovir DF (TDF) + abacavir (ABC) and lamivudine (3TC) in a randomized trial compared to efavirenz (EFV) + ABC and 3TC: ESS30009 unplanned interim analysis. In Programme and Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy, Chicago, IL, September 14-17. Abstract H-1722a.
    • (2003) Programme and Abstracts of the 43rd Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Gallant, J.1    Rodriguez, A.2    Weinberg, W.3
  • 25
    • 3042848853 scopus 로고    scopus 로고
    • Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: A 3-year randomized trial
    • GALLANT, J.E., STASZEWSKI, S., POZNIAK, A.L., DEJESUS, E., SULEIMAN, J.M., MILLER, M.D., COAKLEY, D.F., LU, B., TOOLE, J.J., CHENG, A.K., AND 903 STUDY GROUP. (2004). Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial. JAMA, 292, 191-201.
    • (2004) JAMA , vol.292 , pp. 191-201
    • Gallant, J.E.1    Staszewski, S.2    Pozniak, A.L.3    DeJesus, E.4    Suleiman, J.M.5    Miller, M.D.6    Coakley, D.F.7    Lu, B.8    Toole, J.J.9    Cheng, A.K.10
  • 26
    • 3843151487 scopus 로고    scopus 로고
    • SOLO: 48-Week efficacy and safety comparison of once-daily fosamprenavir/ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients
    • GATHE, J.C., JR, IVE, P., WOOD, R., SCHURMANN, D., BELLOS, N.C., DEJESUS, E., GLADYSZ, A., GARRIS, C., AND YEO, J. (2004a). SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir/ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients. AIDS, 18, 1529-1537.
    • (2004) AIDS , vol.18 , pp. 1529-1537
    • Gathe Jr., J.C.1    Ive, P.2    Wood, R.3    Schurmann, D.4    Bellos, N.C.5    DeJesus, E.6    Gladysz, A.7    Garris, C.8    Yeo, J.9
  • 32
    • 23844498763 scopus 로고    scopus 로고
    • Risk factors for and outcome of hyperlactatemia in HIV-infected persons: Is there a need for routine lactate monitoring?
    • IMHOF, A., LEDERGERBER, B., GUNTHARD, H.F., HAUPTS, S., WEBER, R., AND SWISS HIV COHORT STUDY. (2005). Risk factors for and outcome of hyperlactatemia in HIV-infected persons: is there a need for routine lactate monitoring? Clin. Infect. Dis., 41, 721-728.
    • (2005) Clin. Infect. Dis. , vol.41 , pp. 721-728
    • Imhof, A.1    Ledergerber, B.2    Gunthard, H.F.3    Haupts, S.4    Weber, R.5
  • 33
    • 4444290304 scopus 로고    scopus 로고
    • Poor virologic responses and early emergence of resistance in treatment naive, HIV-infected patients receiving a once daily triple nucleoside regimen of didanosine, lamivudine, and tenofovir DF
    • San Francisco, CA, February 8-11. Abstract 51
    • JEMSEK, J., HUTCHERSON, P., AND E. HARPER. (2004). Poor virologic responses and early emergence of resistance in treatment naive, HIV-infected patients receiving a once daily triple nucleoside regimen of didanosine, lamivudine, and tenofovir DF. In Programme and Abstracts of the 11th Conference on Retroviruses and Opportunistic Infections, San Francisco, CA, February 8-11. Abstract 51.
    • (2004) Programme and Abstracts of the 11th Conference on Retroviruses and Opportunistic Infections
    • Jemsek, J.1    Hutcherson, P.2    Harper, E.3
  • 36
    • 0037626084 scopus 로고    scopus 로고
    • Phenotypic susceptibility and virological outcome in nucleoside- experienced patients receiving three or four antiretroviral drugs
    • KATZENSTEIN, D.A., BOSCH, R.J., HELLMANN, N., WANG, N., BACHELER, L., ALBRECHT, M.A., AND ACTG 364 STUDY TEAM. (2003). Phenotypic susceptibility and virological outcome in nucleoside-experienced patients receiving three or four antiretroviral drugs. AIDS, 17, 821-830.
    • (2003) AIDS , vol.17 , pp. 821-830
    • Katzenstein, D.A.1    Bosch, R.J.2    Hellmann, N.3    Wang, N.4    Bacheler, L.5    Albrecht, M.A.6
  • 37
    • 0031802175 scopus 로고    scopus 로고
    • Emergence of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 variants, viral sequence variation, and disease progression in patients receiving antiretroviral chemotherapy
    • KAVLICK, M.F., WYVILL, K., YARCHOAN, R., AND MITSUYA, H. (1998). Emergence of multi-dideoxynucleoside-resistant human immunodeficiency virus type 1 variants, viral sequence variation, and disease progression in patients receiving antiretroviral chemotherapy. J. Infect. Dis., 177, 1506-1513.
    • (1998) J. Infect. Dis. , vol.177 , pp. 1506-1513
    • Kavlick, M.F.1    Wyvill, K.2    Yarchoan, R.3    Mitsuya, H.4
  • 38
    • 9144271024 scopus 로고    scopus 로고
    • Incidence of resistance in a double-blind study comparing lopinavir/ritonavir plus stavudine and lamivudine to nelfinavir plus stavudine and lamivudine
    • KEMPF, D.J., KING, M.S., BERNSTEIN, B., CERNOHOUS, P., BAUER, E., MOSELEY, J., GU, K., HSU, A., BRUN, S., AND SUN, E. (2004). Incidence of resistance in a double-blind study comparing lopinavir/ritonavir plus stavudine and lamivudine to nelfinavir plus stavudine and lamivudine. J. Infect. Dis., 189, 51-60.
    • (2004) J. Infect. Dis. , vol.189 , pp. 51-60
    • Kempf, D.J.1    King, M.S.2    Bernstein, B.3    Cernohous, P.4    Bauer, E.5    Moseley, J.6    Gu, K.7    Hsu, A.8    Brun, S.9    Sun, E.10
  • 39
    • 8944256865 scopus 로고    scopus 로고
    • Drug resistance and virologic response in NUCA 3001, a randomized trial of lamivudine (3TC) versus zidovudine (ZDV) versus ZDV plus 3TC in previously untreated patients
    • KURITZKES, D.R., QUINN, J.B., BENOIT, S.L., SHUGARTS, D.L., GRIFFIN, A., BAKHTIARI, M., POTICHA, D., ERON, J.J., FALLON, M.A., AND RUBIN, M. (1996). Drug resistance and virologic response in NUCA 3001, a randomized trial of lamivudine (3TC) versus zidovudine (ZDV) versus ZDV plus 3TC in previously untreated patients. AIDS, 10, 975-981.
    • (1996) AIDS , vol.10 , pp. 975-981
    • Kuritzkes, D.R.1    Quinn, J.B.2    Benoit, S.L.3    Shugarts, D.L.4    Griffin, A.5    Bakhtiari, M.6    Poticha, D.7    Eron, J.J.8    Fallon, M.A.9    Rubin, M.10
  • 42
    • 12144290105 scopus 로고    scopus 로고
    • Antiviral efficacy of abacavir in antiretroviral therapy-experienced adults harbouring HIV-1 with specific patterns of resistance to nucleoside reverse transcriptase inhibitors
    • LANIER, E.R., AIT-KHALED, M., SCOTT, J., STONE, C., MELBY, T., STURGE, G., ST CLAIR, M., STEEL, H., HETHERINGTON, S., PEARCE, G., SPREEN, W., AND LAFON, S. (2004). Antiviral efficacy of abacavir in antiretroviral therapy-experienced adults harbouring HIV-1 with specific patterns of resistance to nucleoside reverse transcriptase inhibitors. Antivir Ther., 9, 37-45.
    • (2004) Antivir. Ther. , vol.9 , pp. 37-45
    • Lanier, E.R.1    Ait-Khaled, M.2    Scott, J.3    Stone, C.4    Melby, T.5    Sturge, G.6    St. Clair, M.7    Steel, H.8    Hetherington, S.9    Pearce, G.10    Spreen, W.11    Lafon, S.12
  • 44
    • 1642283134 scopus 로고    scopus 로고
    • GW433908/ritonavir once daily in antiretroviral therapy-naive HIV-infected patients: Absence of protease resistance at 48 weeks
    • MACMANUS, S., YATES, P.J., ELSTON, R.C., WHITE, S., RICHARDS, N., AND SNOWDEN, W. (2004). GW433908/ritonavir once daily in antiretroviral therapy-naive HIV-infected patients: absence of protease resistance at 48 weeks. AIDS, 18, 651-655.
    • (2004) AIDS , vol.18 , pp. 651-655
    • MacManus, S.1    Yates, P.J.2    Elston, R.C.3    White, S.4    Richards, N.5    Snowden, W.6
  • 45
    • 0035715574 scopus 로고    scopus 로고
    • Virological and immunological responses to a once-a-day antiretroviral regimen with didanosine, lamivudine and efavirenz
    • MAGGIOLO, F., MIGLIORINO, M., MASERATI, R., PAN, A., RIZZI, M., PROVETTONI, G., RIZZI, L., SUTER, F., AND ONCE STUDY GROUP. (2001). Virological and immunological responses to a once-a-day antiretroviral regimen with didanosine, lamivudine and efavirenz. Antivir Ther, 6, 249-253.
    • (2001) Antivir Ther , vol.6 , pp. 249-253
    • Maggiolo, F.1    Migliorino, M.2    Maserati, R.3    Pan, A.4    Rizzi, M.5    Provettoni, G.6    Rizzi, L.7    Suter, F.8
  • 47
    • 20844435624 scopus 로고    scopus 로고
    • In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA
    • MALLON, P.W., UNEMORI, P., SEDWELL, R., MOREY, A., RAFFERTY, M., WILLIAMS, K., CHISHOLM, D., SAMARAS, K., EMERY, S., KELLEHER, A., COOPER, D.A., CARR, A., AND SAMA INVESTIGATORS. (2005). In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA. J. Infect. Dis. 191, 1686-1696.
    • (2005) J. Infect. Dis. , vol.191 , pp. 1686-1696
    • Mallon, P.W.1    Unemori, P.2    Sedwell, R.3    Morey, A.4    Rafferty, M.5    Williams, K.6    Chisholm, D.7    Samaras, K.8    Emery, S.9    Kelleher, A.10    Cooper, D.A.11    Carr, A.12
  • 54
    • 0032506228 scopus 로고    scopus 로고
    • Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism
    • U. S. A.
    • MEYER, P.R., MATSUURA, S.E., SO, A.G., AND SCOTT, W.A. (1998). Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism. Proc. Natl. Acad. Sci. U. S. A. 95, 13471-13476.
    • (1998) Proc. Natl. Acad. Sci. , vol.95 , pp. 13471-13476
    • Meyer, P.R.1    Matsuura, S.E.2    So, A.G.3    Scott, W.A.4
  • 55
    • 1542327561 scopus 로고    scopus 로고
    • Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral-experienced patients
    • MILLER, M.D., N. MARGOT, B. LU, L. ZHONG, S. S. CHEN, A. CHENG, AND M. WULFSOHN. (2004). Genotypic and phenotypic predictors of the magnitude of response to tenofovir disoproxil fumarate treatment in antiretroviral- experienced patients. J. Infect. Dis., 189, 837-846.
    • (2004) J. Infect. Dis. , vol.189 , pp. 837-846
    • Miller, M.D.1    Margot, N.2    Lu, B.3    Zhong, L.4    Chen, S.S.5    Cheng, A.6    Wulfsohn, M.7
  • 57
    • 15044341385 scopus 로고    scopus 로고
    • Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviral-naive HIV-infected adults: Results of the Ziagen Once Daily in Antiretroviral Combination Study
    • MOYLE, G.J., DEJESUS, E., CAHN, P., CASTILLO, S.A., ZHAO, H., GORDON, D.N., CRAIG, C., SCOTT, T.R. AND ZIAGEN ONCE-DAILY IN ANTIRETROVIRAL COMBINATION THERAPY (CNA30021) STUDY TEAM. (2005). Abacavir once or twice daily combined with once-daily lamivudine and efavirenz for the treatment of antiretroviral-naive HIV-infected adults: results of the Ziagen Once Daily in Antiretroviral Combination Study. J. Acquir. Immune Defic. Syndr., 38, 417-425.
    • (2005) J. Acquir. Immune Defic. Syndr. , vol.38 , pp. 417-425
    • Moyle, G.J.1    DeJesus, E.2    Cahn, P.3    Castillo, S.A.4    Zhao, H.5    Gordon, D.N.6    Craig, C.7    Scott, T.R.8
  • 58
    • 0037999080 scopus 로고    scopus 로고
    • Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy
    • NOLAN, D., HAMMOND, E., MARTIN, A., TAYLOR, L., HERRMANN, S., MCKINNON, E., METCALF, C., LATHAM, B., AND MALLAL, S. (2003). Mitochondrial DNA depletion and morphologic changes in adipocytes associated with nucleoside reverse transcriptase inhibitor therapy. AIDS, 17, 1329-1338.
    • (2003) AIDS , vol.17 , pp. 1329-1338
    • Nolan, D.1    Hammond, E.2    Martin, A.3    Taylor, L.4    Herrmann, S.5    McKinnon, E.6    Metcalf, C.7    Latham, B.8    Mallal, S.9
  • 61
    • 0035884247 scopus 로고    scopus 로고
    • Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine
    • PICARD, V., ANGELINI, E., MAILLARD, A., RACE, E., CLAVEL, F., CHENE, G., FERCHAL, F., AND MOLINA, J.M. (2001). Comparison of genotypic and phenotypic resistance patterns of human immunodeficiency virus type 1 isolates from patients treated with stavudine and didanosine or zidovudine and lamivudine. J. Infect. Dis. 184, 781-784.
    • (2001) J. Infect. Dis. , vol.184 , pp. 781-784
    • Picard, V.1    Angelini, E.2    Maillard, A.3    Race, E.4    Clavel, F.5    Chene, G.6    Ferchal, F.7    Molina, J.M.8
  • 62
    • 0032750441 scopus 로고    scopus 로고
    • Predictors of optimal virological response to potent antiretroviral therapy
    • POWDERLY, W.G., SAAG, M.S. CHAPMAN, S., YU, G., QUART, B., AND CLENDENINN, N.J. (1999). Predictors of optimal virological response to potent antiretroviral therapy. AIDS, 13, 1873-1880.
    • (1999) AIDS , vol.13 , pp. 1873-1880
    • Powderly, W.G.1    Saag, M.S.2    Chapman, S.3    Yu, G.4    Quart, B.5    Clendeninn, N.J.6
  • 63
    • 19644395095 scopus 로고    scopus 로고
    • Lipodystrophy and dyslipidemia among patients taking first-line, world health organization-recommended highly active antiretroviral therapy regimens in Western India
    • PUJARI, S.N., DRAVID, A., NAIK, E., BHAGAT, S., TASH, K., NADLER, J.P. AND SINNOTT, J.T. (2005). Lipodystrophy and dyslipidemia among patients taking first-line, world health organization-recommended highly active antiretroviral therapy regimens in Western India. J. Acquir. Immune Defic. Syndr., 39, 199-202.
    • (2005) J. Acquir. Immune Defic. Syndr. , vol.39 , pp. 199-202
    • Pujari, S.N.1    Dravid, A.2    Naik, E.3    Bhagat, S.4    Tash, K.5    Nadler, J.P.6    Sinnott, J.T.7
  • 66
    • 0347990584 scopus 로고    scopus 로고
    • The NEAT study: A 48-week open-label study to compare the antiviral efficacy and safety of GW433908 versus nelfinavir in antiretroviral therapy-naive HIV-1-infected patients
    • RODRIGUEZ-FRENCH, A., BOGHOSSIAN, J., GRAY, G.E., NADLER, J.P., QUINONES, A.R., SEPULVEDA, G.E. MILLARD, J.M., AND WANNAMAKER, P.G. (2004). The NEAT study: a 48-week open-label study to compare the antiviral efficacy and safety of GW433908 versus nelfinavir in antiretroviral therapy-naive HIV-1-infected patients. J. Acquir. Immune Defic. Syndr., 35, 22-32.
    • (2004) J. Acquir. Immune Defic. Syndr. , vol.35 , pp. 22-32
    • Rodriguez-French, A.1    Boghossian, J.2    Gray, G.E.3    Nadler, J.P.4    Quinones, A.R.5    Sepulveda, G.E.6    Millard, J.M.7    Wannamaker, P.G.8
  • 68
    • 0036222716 scopus 로고    scopus 로고
    • Genotypic testing for human immunodeficiency virus type 1 drug resistance
    • SHAFER, R.W. (2002). Genotypic testing for human immunodeficiency virus type 1 drug resistance. Clin. Microbiol. Rev., 15, 247-277.
    • (2002) Clin. Microbiol. Rev. , vol.15 , pp. 247-277
    • Shafer, R.W.1
  • 72
    • 0033576816 scopus 로고    scopus 로고
    • Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults
    • Study 006 Team
    • STASZEWSKI, S., MORALES-RAMIREZ, J., TASHIMA, K.T., RACHLIS, A., SKIEST, D., STANFORD, J., STRYKER, R., JOHNSON, P., LABRIOLA, D.F., FARINA, D., D.J., AND RUIZ, N.M. (1999). Efavirenz plus zidovudine and lamivudine, efavirenz plus indinavir, and indinavir plus zidovudine and lamivudine in the treatment of HIV-1 infection in adults. Study 006 Team. N. Engl. J. Med., 341, 1865-1873.
    • (1999) N. Engl. J. Med. , vol.341 , pp. 1865-1873
    • Staszewski, S.1    Morales-Ramirez, J.2    Tashima, K.T.3    Rachlis, A.4    Skiest, D.5    Stanford, J.6    Stryker, R.7    Johnson, P.8    Labriola, D.F.9    Farina, D.10    Ruiz, N.M.11
  • 74
    • 0035805176 scopus 로고    scopus 로고
    • Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection
    • VAN DER VALK, M., GISOLF, E.H., REISS, P., WIT, F.W., JAPOUR, A., WEVERLING, G.J., DANNER, S.A., AND PROMETHEUS STUDY GROUP. (2001). Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection. AIDS, 15, 847-855.
    • (2001) AIDS , vol.15 , pp. 847-855
    • Van Der Valk, M.1    Gisolf, E.H.2    Reiss, P.3    Wit, F.W.4    Japour, A.5    Weverling, G.J.6    Danner, S.A.7
  • 76
    • 4444303205 scopus 로고    scopus 로고
    • Resistance issues with new nucleoside/nucleotide backbone options
    • WAINBERG, M.A. AND TURNER, D. (2004). Resistance issues with new nucleoside/nucleotide backbone options. J. Acquir. Immune Defic. Syndr., 37, Suppl 1, S36-43.
    • (2004) J. Acquir. Immune Defic. Syndr. , vol.37 , Issue.1 SUPPL.
    • Wainberg, M.A.1    Turner, D.2
  • 77
    • 0037045058 scopus 로고    scopus 로고
    • Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors
    • WALKER, U.A., SETZER, B., AND VENHOFF, N. (2002). Increased long-term mitochondrial toxicity in combinations of nucleoside analogue reverse-transcriptase inhibitors. AIDS, 16, 2165-2173.
    • (2002) AIDS , vol.16 , pp. 2165-2173
    • Walker, U.A.1    Setzer, B.2    Venhoff, N.3
  • 79
    • 14944352535 scopus 로고    scopus 로고
    • Diminished replicative fitness of primary human immunodeficiency virus type 1 isolates harboring the K65R mutation
    • WEBER, J., CHAKRABORTY, B., WEBEROVA, J., MILLER, M.D., AND QUINONES-MATEU, M.E. (2005). Diminished replicative fitness of primary human immunodeficiency virus type 1 isolates harboring the K65R mutation. J. Clin. Microbiol., 43, 1395-1400.
    • (2005) J. Clin. Microbiol. , vol.43 , pp. 1395-1400
    • Weber, J.1    Chakraborty, B.2    Weberova, J.3    Miller, M.D.4    Quinones-Mateu, M.E.5
  • 82
    • 0142042463 scopus 로고    scopus 로고
    • Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates
    • WHITCOMB, J.M., PARKIN, N.T., CHAPPEY, C., HELLMANN, N.S., AND PETROPOULOS, C.J. (2003). Broad nucleoside reverse-transcriptase inhibitor cross-resistance in human immunodeficiency virus type 1 clinical isolates. J. Infect. Dis., 188, 992-1000.
    • (2003) J. Infect. Dis. , vol.188 , pp. 992-1000
    • Whitcomb, J.M.1    Parkin, N.T.2    Chappey, C.3    Hellmann, N.S.4    Petropoulos, C.J.5
  • 83
    • 0036839746 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity
    • WHITE, K.L., MARGOT, N.A., WRIN, T., PETROPOULOS, C.J., MILLER, M.D., AND NAEGER, L.K. (2002). Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity. Antimicrob. Agents Chemother., 46, 3437-3446.
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 3437-3446
    • White, K.L.1    Margot, N.A.2    Wrin, T.3    Petropoulos, C.J.4    Miller, M.D.5    Naeger, L.K.6
  • 84
    • 0041941502 scopus 로고    scopus 로고
    • Clinical impact of the M184V mutation on switching to didanosine or maintaining lamivudine treatment in nucleoside reverse-transcriptase inhibitor-experienced patients
    • WINTERS, M.A., BOSCH, R.J., ALBRECHT, M.A., KATZENSTEIN, D.A., AND AIDS CLINICAL TRIALS GROUP 364 STUDY TEAM. (2003). Clinical impact of the M184V mutation on switching to didanosine or maintaining lamivudine treatment in nucleoside reverse-transcriptase inhibitor-experienced patients. J. Infect. Dis., 188, 537-540.
    • (2003) J. Infect. Dis. , vol.188 , pp. 537-540
    • Winters, M.A.1    Bosch, R.J.2    Albrecht, M.A.3    Katzenstein, D.A.4
  • 85
    • 0034622992 scopus 로고    scopus 로고
    • Full suppression of viral load is needed to achieve an optimal CD4 cell count response among patients on triple drug antiretroviral therapy
    • WOOD, E.,B. YIP, HOGG, R.S. SHERLOCK, C.H., JAHNKE, N., HARRIGAN, R.P.,. O'SHAUGHNESSY, M.V., AND MONTANER, J.S. (2000). Full suppression of viral load is needed to achieve an optimal CD4 cell count response among patients on triple drug antiretroviral therapy. AIDS, 14, 1955-1960.
    • (2000) AIDS , vol.14 , pp. 1955-1960
    • Wood, E.1    Yip, B.2    Hogg, R.S.3    Sherlock, C.H.4    Jahnke, N.5    Harrigan, R.P.6    O'Shaughnessy, M.V.7    Montaner, J.S.8
  • 87
    • 21844462147 scopus 로고    scopus 로고
    • Multiple drug class-wide resistance associated with poorer survival after treatment failure in a cohort of HIV-infected patients
    • ZACCARELLI, M., TOZZI, V., LORENZINI, P., TROTTA, M.P., FORBICI, F., VISCO-COMANDINI, U., GORI, C., NARCISO P., PERNO, C,F., ANTINORI, A., AND COLLABORATIVE GROUP FOR CLINICAL USE OF HIV GENOTYPE RESISTANCE TEST (GRT) AT NATIONAL INSTITUTE FOR INFECTIOUS DISEASES LAZZARO SPALLANZANI. (2005). Multiple drug class-wide resistance associated with poorer survival after treatment failure in a cohort of HIV-infected patients. AIDS, 19, 1081-1089.
    • (2005) AIDS , vol.19 , pp. 1081-1089
    • Zaccarelli, M.1    Tozzi, V.2    Lorenzini, P.3    Trotta, M.P.4    Forbici, F.5    Visco-Comandini, U.6    Gori, C.7    Narciso, P.8    Perno, C.9    Antinori, A.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.