Human cytomegalovirus latency is associated with the state of differentiation of the host cells: An in vitro model in teratocarcinoma cells

Acta Microbiologica et Immunologica Hungarica

Volumn 52, Issue 3-4, 2005, Pages 397-406

  Dósa, Réka ^a   Burián, Katalin ^b   Gönczöl, Éva ^c  

^a Sankt George County Hospital Fogolyán Kristóf   (Romania)

^b UNIVERSITY OF SZEGED   (Hungary)

^c NATIONAL CENTER FOR EPIDEMIOLOGY   (Hungary)

Author keywords

Human cytomegalovirus latency; Teratocarcinoma cells

Indexed keywords

HUMAN HERPESVIRUS 5;

EID: 29144506059     PISSN: 12178950     EISSN: 15882640     Source Type: Journal    
DOI: 10.1556/AMicr.52.2005.3-4.11     Document Type: Article

References (32)

1. Xu, X. N., Screaton, G. R., McMichael, A. J.: Virus infections: escape, resistance, and counterattack. Immunity 15, 867-870 (2001).
2. Martin, G. R.: Teratocarcinomas and mammalian embryogenesis. Science 209, 768 (1980).
3. Andrews, P. W., Damjanov, I., Simon, D., Banting, G. S., Carlin, C., Dracopoli, N. C., Fogh, J.: Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Lab Invest 50, 147-161 (1984).
4. Gonczol, E., Andrews, P. W., Plotkin, S. A.: Cytomegalovirus replicates in differentiated but not in undifferentiated human embryonal carcinoma cells. Science 224, 159-161 (1984).
5. Gonczol, E., Andrews, P. W., Plotkin, S. A.: Cytomegalovirus infection of human teratocarcinoma cells in culture. J Gen Virol 66, 509-515 (1985).
6. Andrews, P. W., Gonczol, E., Plotkin, S. A., Dignazio, M., Oosterhuis, J. W.: Differentiation of TERA-2 human embryonal carcinoma cells into neurons and HCMV permissive cells. Induction by agents other than retinoic acid. Differentiation 31, 119-126 (1986).
7. Andrews, P. W., Gonczol, E., Fenderson, B., Holmes, E. H., Omalley, G., Hakomori, S. I., Plotkin, S. A.: Human cytomegalovirus induces stage-specific embryonic antigen 1 in differentiating human teratocarcinoma cells and fibroblasts. J Exp Med 169, 1347-1359 (1989).
8. Mocarski, E. S., Courcelle, C. T.: Cytomegalovirus and their replication. In: Knipe, D. M., Howley, P. M. (eds): Fields Virology. Fourth Edition, Lippincott Williams and Wilkins, Philadelphia, 2001, pp. 2629-2673.
9. Pizzorno, M. C., Hayward, G. S.: The IE2 gene products of human cytomegalovirus specifically down-regulate expression from the major immediate-early promoter through a target located near the cap site. J Virol 64, 6154-6165 (1990).
10. Malone, C. I., Vesole, D. H., Stinski, M. F.: Transactivation of a human cytomegalovirus early promoter by gene products from the intermediate-early gene IE2 and augmentation by IE2: mutational analysis of the viral proteins. J Virol 64, 1498-1506 (1990).
11. Meier, J. L., Stinski, M. F.: Regulation of human cytomegalovirus immediate-early gene expression. Intervirology 39, 331-342 (1996).
12. Yang, W. M., Inouye, C., Zeng, Y., Bearss, D., Seto, E.: Transcriptional repression by YY1 is mediated by interaction with a mammalian homolog of the yeast global regulator RPD3. Proc Natl Acad Sci USA 93, 12845-12850 (1996).
13. Yao, Y. L., Yang, W. M., Seto, E.: Regulation of transcription factor YY1 by acetylation and deacetylation. Mol Cell Biol 21, 5979-5991 (2001).
14. Bain, M., Mendelson, M., Sinclair, J.: Ets-2 repressor factor (ERF) mediates repression of the human cytomegalovirus major immediate-early promoter in undifferentiated non-permissive cells. J Gen Virol 84, 41-49 (2003).
15. Isomura, H., Tsurumi, T., Stinski, M. F.: Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication. J Virol 78, 12788-12799 (2004).
16. LaFemina, R., Hayward, G. S.: Constitutive and retinoic acid-inducible expression of cytomegalovirus immediate-early genes in human teratocarcinoma cells. J Virol 58, 434-440 (1986).
17. Nelson, J. A., Groudine, M.: Transcriptional regulation of the human cytomegalovirus major immediate-early gene is associated with induction of DNase I-hypersensitive sites. Mol Cell Biol 6, 452-461 (1986).
18. Nelson, J. A., Reynolds-Kohler, C., Smith, B. A.: Negative and positive regulation by a short segment in the 5′-flanking region of the human cytomegalovirus major immediate-early gene. Mol Cell Biol 7, 4125-4129 (1987).
19. Shelbourn, S. L., Kothari, S. K., Sissons, J. G. P., Sinclair, J. H.: Repression of human cytomegalovirus gene expression associated with a novel immediate early regulatory region binding factor. Nucleic Acids Research 17, 9165-9171 (1989).
20. Kothari, S., Baillie, J., Sissons, J. G. P., Sinclair, J. H.: The 21 bp repeat element of the human cytomegalovirus major immediate early enhancer is a negative regulator of gene expression in undifferentiated cells. Nucleic Acids Research 19, 1767-1771 (1991).
21. Shelbourn, S. L., Sissons, J. G. P., Sinclair, J. H.: Expression of oncogenic ras in human teratocarcinoma cells induces partial differentiation and permissiveness for human cytomegalovirus infection. J Gen Virol 70, 367-374 (1989).
22. Flanagan, J. R., Krieg, A. M., Max, E. E., Khan, A. S.: Negative control region at the 5′ end of murine leukemia virus long terminal repeats. Mol Cell Biol 9, 739-746 (1989).
23. Liu, R., Baillie, J., Sissons, J. G. P., Sinclair, J. H.: The transcription factor YY1 binds to negative regulatory elements in the human cytomegalovirus major immediate early enhancer/promoter and mediates repression in non-permissive cells. Nucleic Acid Research 22, 2453-2459 (1994).
24. Montalvo, E. A., Shi, Y., Shenk, T. E., Levine, A. J.: Negative regulation of the BZLF1 promoter of Epstein-Barr virus. J Virol 65, 3647-3655 (1991).
25. Meier, J. L.: Reactivation of the human cytomegalovirus major immediate-early regulatory region and viral replication in embryonal NTera2 cells: role of trichostatin A, retinoic acid, and deletion of the 21-base-pair repeats and modulator. J Virol 75, 1581-1593 (2001).
26. Rideg, K., Hirka, G., Prakash, K., Bushar, L. M., Nothias, J. Y., Weinmann, R., Andrews, P. W., Gonczol, E.: DNA-binding proteins that interact with the 19-base pair (CRE-like) element from the HCMV major immediate early promoter differentiating human embryonal carcinoma cells. Differentiation 56, 119-129 (1994).
27. Murphy, J. C., Fischle, W., Verdin, E., Sinclair, J. H.: Control of cytomegalovirus lytic gene expression by histone acetylation. The EMBO Journal 21, 1112-1120 (2002).
28. Sinclair, J. H., Sissons, J. G. P.: Latent and persistent infections of monocytes and macrophages. Intervirology 39, 293-301 (1996).
29. Wright, E., Bain, M., Teague, L., Murphy, J., Sinclair, J.: Ets-2 repressor factor recruits histone deacetylase to silence human cytomegalovirus immediate-early gene expression in non-permissive cells. J Gen Virol 86, 535-544 (2004).
30. Sissons, J. G. P., Bain, M., Wills, M. R., Sinclair, J. H.: Latency and reactivation of human cytomegalovirus. Journal of Infection 44, 73-77 (2002).
31. Sinzger, C., Jahn, G.: Human cytomegalovirus cell tropism and pathogenesis. Intervirology 39, 302-319 (1996).
32. Reeves, M. B., MacAry, P. A., Lehner, P. J., Sissons, J. P. G., Sinclair, J. H.: Latency, chromatin remodeling, and reactivation of human cytomegalovirus in the dendritic cells of healthy carriers. Proc Nat Acad Sci 102, 4140-4145 (2005).