Latent and persistent infections of monocytes and macrophages

Intervirology

Volumn 39, Issue 5-6, 1996, Pages 293-301

  Sinclair, John ^a   Sissons, Patrick ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Human cytomegalovirus; Immediate early repression; Latency; Myeloid cells; Persistence

Indexed keywords

ARTICLE; CELL DIFFERENTIATION; CYTOMEGALIC INCLUSION BODY DISEASE; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CYTOMEGALOVIRUS; LATENT VIRUS INFECTION; MACROPHAGE; MONOCYTE; NONHUMAN; PERSISTENT VIRUS INFECTION; PRIORITY JOURNAL; VIRUS CELL INTERACTION; VIRUS REACTIVATION;

ANIMALS; CELL DIFFERENTIATION; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; HUMANS; LEUKOCYTES, MONONUCLEAR; MACROPHAGES; MONOCYTES; STEM CELLS; VIREMIA; VIRUS LATENCY;

HUMAN HERPESVIRUS 5;

EID: 0030434480     PISSN: 03005526     EISSN: 14230100     Source Type: Journal    
DOI: 10.1159/000150501     Document Type: Article

References (71)

1. Rubin RH: Impact of cytomegalovirus infection on organ transplant recipients, Rev Infect Dis 1990:12:S754-S762.
2. Stinski MF, Macias MP, Malone CL, Thrower AR, Huang L: Regulation of transcription from the cytomegalovirus major immediate early promoter by cellular and viral proteins; in Mi-chelson S, Plotkin SA (eds): Multidiciplinary Approach to Understanding Cytomegalovirus Disease, New York, Elsevier, 1993, pp 3-12.
3. Malone CL, Vesole DLL Stinski MF: Transactivation of a human cytomegalovirus early promoter by gene products from the immediate early gene 1E2 and augmentation by IE 1: Mutational analysis of the viral proteins, J Virol 1990;64:1498-1506.
4. Colberg-Poley AM, Santomenna L.D, Harlow PP, Benfield P, Tenney DJ: Human cytomegalovirus US3 and UL36-38 immediate early proteins regulate gene expression, J Virol 1992: 66:95-105.
5. Hagemeier C, Walker SM, Sissons JGP, Sinclair JH: The 72k IE1 and 80k 1E2 proteins of human cytomegalovirus independently trans-aclivate the c-fos, c-wye and hsp70 promoters via basal promoter elements, J Gen Virol 1992: 73:2385-2393.
6. Sinzger C, Greftc A, Plachter B, Gouw ASH, The TH, Jahn G: Fibroblasts, epithelial cells, endothelial cells and smooth muscle cells arc-major targets of HCMV infection in lung and gastrointestinal tissue, J Gen Virol 1995:76: 741-750.
7. Tolpin MD, Stewart JA, Warren D, Mojica BA, Collins MA, Doveikis SA, Cabradilla C, Schauf V, Raju TNK, Nelson K: Transfusion transmission of cytomegalovirus confirmed by restriction endonuclease analysis, J Pcdiatr 1985; 107:953-956.
8. Adler SP: Transfusion-associated cytomegalovirus infections, Rev Infect Dis 1983:5:977-993.
9. Yeager AS, Grumel FC, Halleigh EB, Arvin AM, Bradley JS, Prober CG: Prevention of transfusion-acquired cytomegalovirus infections in newborn infants, J Pediatr 1981:98: 281-287.
10. DeGraan-Hcntzen YCE, Gratama JW, Mudde GC, Verdonck LF, Houbicrs JGA, Brand A, Sebens FW, VanLoon AM, The TH, Willemze R, DcGast GC: Prevention of primary cytomegalovirus infection in patients with hematologic malignancies by intensive white cell depletion of blood products, Transfusion 1989: 29:757-760.
11. Jordan MC: Latent infection and the elusive cytomegalovirus, Rev Infect Dis 1983:5:205- 215.
12. Schrier RD, Nelson JA, Oldstone MBA: Detection of human cytomegalovirus in peripheral blood lymphocytes in a natural infection, Science 1985:230:1048-1051.
13. Stannier P, Taylor DL, Kitchen AD, Wales N, T ryhorn Y, T yms AS: Persistence of cytomegalovirus in mononuclear cells in peripheral blood front blood donors, Br Med J 1989:299: 897-898.
14. Taylor-Wiedeman JA, Sissons JGP, Borysie-wicz LK, Sinclair JH: Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells, J Gen Virol 1991:72:2059-2064.
15. Urushibar N, Kwon K-W, Takahashi TA, Seki-guchi S: HCMV DNA is not detectable with nested double polymerase chain reaction in healthy blood donors, Vox Sang 1995:68:9-14.
16. Taylor-Wiedeman JA, Hayhurst GP, Sissons JGP, Sinclair JH: Polymorphonuclear cells are not sites of persistence of human cytomegalovirus in healthy individuals, J Gen Virol 1993; 74:265-268.
17. Toorkey CB, Carrigan DR: Immunohisto-chemical detection of an immediate early antigen of human cytomegalovirus in normal tissues, J Infect Dis 1989;160:741-751.
18. Gnann JW, Ahlmen J, Svalander C, Olding L, Oldstone MBA, Nelson JA: Inflammatory cells in transplanted kidneys are infected by human cytomegalovirus, Am J Pathol 1988; 132:239- 248.
19. Taylor-Wiedeman JA, Sissons JGP, Sinclair JH: Induction of endogenous human cytomegalovirus gene expression after differentiation of monocytes from healthy carriers, J Virol 1994; 68:1597-1604.
20. Maciejewski JP, Bruening EE, Donahue RE, Sellers SS, Carter C, Young NS, St Jeor S: Infection of mononucleated phagocytes with human cytomegalovirus, Virologv 1993:195: 327-336.
21. Rice GPA, Schricr RD, Oldstone MBA: Cytomegalovirus infects human lymphocytes and monocytes: Virus expression is restricted to immediate-early gene products, Proc Nat Acad Sci USA 1984:81:6134-6138.
22. Einhom L, Osl A: Cytomegalovirus infection of human blood cells, J Inf Dis 1984:149:207- 214.
23. Lathey JL, Spector SA: Unrestricted replication of human cytomegalovirus in hydrocortisone-treated macrophages, J Virol 1991:65: 6371-6375.
24. Ibanez CF., Schricr R, Ghazal P, Wiley C, Nelson JA: Human cytomegalovirus productively infects primary differentiated macrophages, J Virol 1991:65:6581-6588.
25. Soderberg C, Larsson S, Bergstedt-Lindqvist S, Möller E: Definition of a subset of human peripheral blood mononuclear cells that are permissive to human cytomegalovirus infection, J Virol 1993:67:3166-3175.
26. Drew WL, Mintz L, Hoo R, Finley TN: Growth of herpes simplex and cytomegalovirus in cultured human alveolar macrophages, Am Rev RespirDis 1979;119:287-291.
27. Sinclair JH, Sissons JGP: HCMV: Pathogenesis and models of latency, Semin Virol 1994:5: 249-258.
28. Metcalf D: The molecular control of cell division, differentiation commitment and maturation in hemopoietic cells, Nature 1989:339:27- 30.
29. Katz FE, Tindlc RW, Sutherland SR, Greaves MF: Identification of a membrane glycoprotein associated with hemopoietic progenitor cells, LeukRcs 1985:9:191-198.
30. Adams DO, Hamilton TA: Molecular transduction mechanisms by which Interferon-y and other signals regulate macrophage development, Immunol Rev 1987:97:5-27.
31. Reiser H, Kuhn J, Doerr HW, Kirchner H, Munk K, Braun R: Human cytomegalovirus replicates in primary human bone marrow cells, J Gen Virol 1986;67:2595-2604.
32. Sing GK, Ruscetti FW: Preferential suppression of myclopoicsis in normal human bone marrow cells, Blood 1990:75:1965-1973.
33. Preiksaitis JK, Janowska A: Persistence of human cytomegalovirus in human long-term bone marrow culture: Relationship to hemopoiesis. J Med Virol 1991;35:76-84.
34. Maciejewski JP, Bruening EE, Donahue RE, Mocarski ES, Young NS, St Jeor SC: Infection of hematopoietic cells by human cytomegalovirus, Blood 1991:80:170-178.
35. Minton EJ, Tvsoc C, Sinclair JH, Sissons JGP: Human cytomegalovirus infection of the monocyte/macrophage lineage, J Virol 1994: 68:4017-4021.
36. Kondo K, Kaneshima H, Mocarski ES: HCMV latent infection of granulocyte-macrophage progenitors, Proc Natl Acad Sci USA 1994:91: 11879-11883.
37. Mcndelson GM, Monard S, Sissons JGP, Sinclair JH: Detection of endogenous human cytomegalovirus in bone marrow progenitors, J Gen Virol, in press.
38. Kondo K, Mocarski ES: Cytomegalovirus latency and latency-specific trasncription in hae-mopoietic progenitors, Scand J Infect Dis 1995;99(suppl):63-67.
39. Apperley JE, Dowding C, Hibbin J, Buiter J, Matutes E, Sissons JGP, Gordon M, Goldman JM: The effect of cytomegalovirus on hemopoiesis: In vitro evidence for selective infection of marrow stromal cells, Exp Hematol 1989; 17: 38-45.
40. Borysiewicz LK, Graham SK, Hickling JK, Mason PD, Sissons JGP: Human cytomegalovirus-specific cytotoxic T cells: Their precursor frequency and stage specificity, J Immunol 1988;18:269-275.
41. Riddell SR, Rabin M, Gaballe A, Britt W, Greerbcrg PD: Class 1 MHC'-restriclcd cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expression, J Immunol 1991:146:2795-2799.
42. Rcvello MG, Pecivallc P, Mattco AD, Morino F, Gerna G: Nuclear expression of the lower matrix protein of human cytomegalovirus in peripheral blood leukocytes of immunocompromised viraemic patients, J Gen Virol 1992; 73:437-442.
43. Minton J: Infection of the monocytic cell lineage by human cytomegalovirus (thesis), University of Cambridge, 1992.
44. Simmons P, Kaushansky K, Torok-Storb B: Mechanisms of cytomegalovirus-mediated myelosupprcssion: Perturbation of stromal function versus direct infection of myeloid cells, Proc Nat Acad Sci USA 1990:87:1386- 1390.
45. Cha T-A, Tom E, Kemble GW, Duke GM, Mocarski E, Spaete RR: HCMV clinical isolates carry at least 19 genes not found in laboratory strains, J Virol 1996:70:78-83.
46. Gonczol E, Andrews PW, Plotkin SA: Cytomegalovirus replicates in differentiated cells but not in undifferentiated human embryonal carcinoma cells, Science 1984:224:159-161.
47. Nelson JA, Groudinc M: Transcriptional regulation of the human cytomegalovirus major-immediate early gene is associated with induction of DNase I hypersensitive sites, Mol Cell Biol 1986:6:452-461.
48. LaFcmina R, Hayward GS: Constitutive and rclinoic acid inducible expression of cytomegalovirus immediate early genes in human terato-carcinoma cells, J Virol 1986:58:434-440.
49. Shclbourn SL, Kothari SK, Sissons JGP, Sinclair JH: Repression of human cytomegalovirus gene expression associated with a novel immediate early regulatory region binding factor, Nucleic Acids Res 1989:17:9165-9171.
50. Weinshenkcr BG, Wilton S, Rice GPA: Phor-bol ester-induced differentiation permits productive human cytomegalovirus infection in a monocytic cell line, J Immunol 1988; 140: 1625-1631.
51. Nelson JA, Reynolds-Kohlcr C, Smith B: Negative and positive regulation by a short segment in the5'-flanking region of the human cytomegalovirus major immediale-earlv gene, Mol Cell Biol 1987:7:4125-4129.
52. Lubon H, Ghazal P, Hcnninghausen L, Rey-nolds-Kohler C, Lockshin C, Nelson JA: Cell specific activity of the modulator region in the human cytomegalovirus major immediate-early gene, Mol Cell Biol 1989:9:1342-1345.
53. Kothari S, Baillie J, Sissons JGP, Sinclair JH: The 21 bp repeat clement of the human cytomegalovirus major immediate early enhancer is a negative regulator of gene expression in undifferentiated cells, Nucleic Acids Res 1991: 19:1767-1771.
54. Sinclair JH, Baillie J, Bryant LA, Taylor-Wicdeman JA, Sissons JGP: Repression of human cytomegalovirus major immediate early gene expression in a monocytic cell line, J Gen Virol 1992;73:433-435.
55. Liu R, Baillie J E, Sissons JGP, Sinclair JH: The transcription factor YYI hinds to negative regulatory elements in the HCMV major immediate early promoter/enhancer and mediates repression in non-permissive cells, Nucleic Acids Res 1994:22:2435-2459.
56. Stinski MF: Regulation of the human cytomegalovirus major immediate early promoter by cellular and viral proteins, XVIII International Herpes Virus Workshop, Pittsburgh, 1993.
57. Bauknecht T, Angel P, Rover H-D, zur Hausen H: Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: Interaction with the transcriptional repressor YY I, EM BO J 1992:11:4607-4617.
58. Montalvo EA, Shi Y, Shcnk T, Levine AJ: Negative regulation of the BZI.F1 promoter of Ep-stein-Barr virus, J Virol 1991:65:3647-3655.
59. LaFemina RL, Hayward GS: Differences in cell type specific blocks to immediate early gene expression and DNA replication of human simian and murine cytomegalovirus, J Gen Virol 1988:69:355-374.
60. Danker WM, McCutcheon JA, Richman DD, Hirata K, Spector SA: Localization of human cytomegalovirus in peripheral blood, J Infect Dis 1990;161:31-36.
61. Jiwa NM, van Gemert GW, Raap AK, van dc Rijke FM, Mulder A, Salimans MMM, Zwaan FE, vanDorp W, van der Plocg M: Rapid detection of human cytomegalovirus DNA in the peripheral blood leukocytes of viremic transplant recipients by the polymerase chain reaction, Transplantation 1989;48:72-76.
62. Bitsch A, Kirchner II, Dupke R, Bein G: Cytomegalovirus transcripts in peripheral blood leukocytes of actively infected transplant patients detected by reverse transcription-poly-merasc chain reaction, J Infect Dis 1993:167: 740-743.
63. Grefte JMM, van der Gun BTF, Schmolke S, van der Geissen M, vanSon WJ, Plachtcr B, Jahn G, The TH: The lower matrix protein pp65 is the principal viral antigen present in peripheral blood leukocytes during active cytomegalovirus infection, J Gen Virol 1992:73: 2923-2932.
64. Greft A, van der Giessen M, vanSon W, The TH: Circulating cytomegalovirus (CMV)-in-fectcd endothelial cells in patients with active CMV infection, J Infect Dis 1993:167:270-277.
65. Myerson D, Hackman RC’, Nelson JA, Ward DC, McDougall JK: Widespread presence of histologically occult cytomegalovirus, Hum Pathol 1984:15:430-439.
66. Mocarski ES, Bonyhadi M, Salimi S, Meune JM, Kaneshima H: HCMV in a SCID-hu mouse: Thymic epithelial cells are prominent targets of viral replication, Proc Nall Acad Sci USA 1993:90:104-108.
67. Waldman JW, Knight DA, Huang ES, Sed-mark DD: Bidirectional transmission of infectious cytomegalovirus between monocytes and vascular endothelial cells - an in vitro model, J Infect Dis 1995:171:263-272.
68. Lathcv JL, Wiley CA, Verity AM, Nelson JA: Cultured human brain capillary' endothelial cells are permissive for human cytomegalovirus, Virology 1990;176:266-273.
69. Collins T, Pomeroy C, Jordan MC: Detection of latent cytomegalovirus DNA in diverse organs of mice, J Infect Dis 1993:168:725-729.
70. Baltliescn M, Mcsserle M, Reddchasc MJ: Lungs are a major site of cytomegalovirus latency and recurrence, J Virol 1993:67:5360-5366.
71. Pollock JL, Virgin HW: Latency, without persistence, of murine cytomegalovirus in the spleen and kidney, J Virol 1995:69:1762-1768.