Pneumococcal phosphorylcholine esterase, Pce, contains a metal binuclear center that is essential for substrate binding and catalysis

Protein Science

Volumn 14, Issue 12, 2005, Pages 3013-3024

  Lagartera, Laura ^a   González, Ana ^b   Hermoso, Juan A ^a   Saíz, José L ^a   García, Pedro ^b   García, José L ^b   Menéndez, Margarita ^a  

^a INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Binuclear zinc center; Catalytic activity; Choline binding proteins; DSC; Pneumococcal Pce; Zinc metallo hydrolases

Indexed keywords

BACTERIAL ENZYME; BUFFER; CHOLINE (4 NITROPHENYL PHOSPHATE); CHOLINE DERIVATIVE; ENZYME; LIPOTEICHOIC ACID; METAL; PNEUMOCOCCAL PHOSPHORYLCHOLINE ESTERASE; TEICHOIC ACID; UNCLASSIFIED DRUG; ZINC; ZINC COMPLEX; ZINC METALLOPHOSPHOESTERASE;

AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL MEMBRANE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; GENE MUTATION; HIGH TEMPERATURE; HYDROGEN BOND; HYDROLYSIS; IONIZATION; PRIORITY JOURNAL; PROTON TRANSPORT; STOICHIOMETRY; STREPTOCOCCUS PNEUMONIAE;

BINDING SITES; CARBOXYLIC ESTER HYDROLASES; CATALYSIS; HYDROGEN-ION CONCENTRATION; HYDROLYSIS; KINETICS; MODELS, MOLECULAR; MUTATION; PHOSPHORYLCHOLINE; PROTEIN STRUCTURE, TERTIARY; STREPTOCOCCUS PNEUMONIAE; SUBSTRATE SPECIFICITY; ZINC;

BACTERIA (MICROORGANISMS); STREPTOCOCCUS PNEUMONIAE;

EID: 28844504495     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.051575005     Document Type: Article

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