Animal Models

Vitiligo: A Monograph on the Basic and Clinical Science

Volumn , Issue , 2008, Pages 281-297

  Lamoreux, Lynn ^a   Boissy, Raymond E ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 28844482462     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470760116.ch33     Document Type: Chapter

References (91)

1. Auclair, B.W., Smith, J.R. Jr, Lamont, S.J. & Briles, W.E. (1984) Effects of the major histo-compatibility complex on delayed amelanosis and associated retinal dystrophy in the DAM chicken. Poultry Science 63,102.
2. Austin, L.M. & Boissy, R.E. (1995) Mammalian tyrosinase-related-protein-1 is recognized by autoantibodies from vitiliginous Smyth chickens. An avian model for human vitiligo. American Journal of Pathology 146,1529-1541.
3. Austin, L.M., Boissy, R.E., Jacobson, B.S. & Smyth, J.R. Jr (1992) The detection of melanocyte autoantibodies in the Smyth chicken model for vitiligo. Clinical Immunology and Immunopathology 64,112-120.
4. Blangero, J., Tissot, R.G., Beattie, C.W. & Amoss, M.S. (1996) Genetic determinants of cutaneous malignant melanoma in Sinclair swine. British Journal of Cancer 73,667-671.
5. Boissy, R.E. & Lamoreux, M.L. (1988) Animal models of an acquired pigmentary disorder-vitiligo. Progress in Clinical & Biological Research 256,207-218.
6. Boissy, R.E., Smyth, J.R. Jr & Fite, K.V. (1983) Progressive cytological changes during the development of delayed feather amelanosis and associated choroidal defects in the DAM chicken line-a vitiligo model. American Journal of Pathology 111, 197-202.
7. Boissy, R.E., Lamont, S.J. & Smyth, J.R. Jr (1984) Persistence of abnormal melanocytes in immunosuppressed chickens of the autoimmune "DAM" line. Cell and Tissue Research 235,663-668.
8. Boissy, R.E., Moellmann, G.E., Trainer, A.T., Smyth, J.R. Jr & Lerner, A.B. (1986)Delayed-amelanotic (DAM or Smyth) chicken: Melanocyte dysfunction in vivo and in vitro. Journal of Investigative Dermatology 86,149-156.
9. Boissy, R.E., Moellmann, G.E. & Lerner, A.B. (1987) Morphology of melanocytes in hair bulbs and eyes of vitiligo mice. American Journal of Pathology 127,380-388.
10. Boissy, R.E., Geeks, S., Smyth, J.R. Jr & Nordlund, J.J. (1988) Ocular pathology in the mini-mally depigmented subline of the vitiliginous Smyth chicken. Pigment Cell Research 1, 303-314.
11. Boissy, R.E., Liu, Y.Y., Medrano, E.E. & Nordlund, J.J. (1991) Structural aberration of the rough endoplasmic reticulum and melanosome compartmentalization in long-term cultures of melanocytes from vitiligo patients. Journal of Investigative Dermatology 97, 395-404.
12. Bowers, R.R. (1988) the melanocyte of the chicken: a review. Progress in Clinical and Biological Research 256,49-63.
13. Bowers, R.R., Harmon, J., Prescott, S., Asano, J. & Wynne, S. (1992) Fowl model for vitiligo: genetic regulation on the fate of the melanocytes. Pigment Cell Research Supplement 2,242-248.
14. Boyle, M.L., Pardue, S.L. & Smyth, J.R. Jr (1987) Effect of corticosterone on the incidence of amelanosis in Smyth delayed amelanotic line chickens. Poultry Science 66,363-367.
15. Bystryn, J.-C., Rigel, D., Friedman, R.J. & Kopf, A. (1987) Prognostic significance of hypopigmentation in malignant melanoma. Archives of Dermatology 123,1053-1055.
16. Cerundolo, R., DeCaprariis, D., Esposito, D.L., Maiolino, P., Restucci, B. & Roperto, F. (1993) Vitiligo in two water buffaloes: histological, histochemical, and ultrastructural investigations. Pigment Cell Research 6,23-28.
17. Cui, J., Chen, D., Misfeldt, M.L., Swinfard, R.W. & Bystryn, J.-C. (1995) Antimelanoma antibodies in swine with spontaneously regressing melanoma. Pigment Cell Research 8, 60-63.
18. Cummings, M.P. & Nordlund, J.J. (1995) Chemical leukoderma; fact or fancy. American Journal of Contact Dermatitis 6,122-127.
19. Dunn, L.C. & Thigpen, L.W. (1930) The silver mouse, a recessive color variation. Journal of Heredity 21,495-498.
20. Erf, G.F. & Smyth, J.R. Jr (1995) Alterations in blood leukocyte populations in Smyth line chickens with autoimmune vitiligo. Poultry Science 75,351-356.
21. Erf, G.F., Trejo-Skalli, A.V. & Smyth, J.R. Jr (1995) T cells in regenerating feathers of Smyth line chickens with vitiligo. Clinical Immunology and Immunopathology 76,120-126.
22. Fishman, P., Merimski, O., Baharav, E. & Shoenfeld, Y. (1997) Autoantibodies to Tyrosinase; the bridge between melanoma and vitiligo. American Cancer Society 79, 1461-1464.
23. Fite, K.V., Whitney, T., Montgomery, N. & Smyth, J.R. Jr (1983) Behavioral and central visual correlates of inherited retinal degeneration in the domestic chicken (Gallus domesticus). Experimental Neurology 79,729-745.
24. Fite, K.V., Bengston, L. & Doran, P. (1985) Retinal pigment epithelial correlates of avian retinal degeneration: Electron microscopic analysis. Journal of Comparative Neurology 231,310-322.
25. Fite, K.V., Pardue, S., Bengston, L., Hayden, D. & Smith, J.R. Jr (1986) Effects of cyclosporine in spontaneous, posterior uveitis. Current Eye Research 5,787-796.
26. Hara, I., Yoshizumi, T. & Houghton, A.N. (1995) Implicating a role for immune recognition of self in tumor rejection: passive immunization against the brown locus protein. Journal of Experimental Medicine 182,1609-1614.
27. Hodgkinson, C.A., Moore, K.J., Nakayama, A., Steingrimsson, E., Copeland, N.G.,Jenkins, N.A. & Arnheiter, H. (1993) Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic helix-loop-helix-zipper protein. Cell 74,395-404.
28. Jackson, I.J., Chambers, D.M., Tsukamoto, K., Copeland, N.J., Gilbert, D.J., Jenkins, N.A.& Hearing, V. (1992) A second tyrosinase-related protein, TRP-2, maps to and is mutated at the mouse slaty locus. EMBO Journal 11,527-535.
29. Jimbow, K., Szabo, G. & Fitzpatrick, T.B. (1974) Ultrastructure investigation ofautophagocytosis of melanosomes and programmed cell death of melanocytes in White Leghorn feather: a study of morphogenetic events leading to hypomelanosis. Developmental Biology 36,8-23.
30. Kawakami, Y. & Rosenberg, S.A. (1997) Immunobiology of human melanoma antigens MART-1 and gplOO and their use for immuno-gene therapy. International Reviews of Immunology 14,173-192.
31. Koh, H.K., Sober, A.J., Nakagawa, H., Albert, D.M., Mihm, M.C. & Fitzpatrick, T.B. (1983) Malignant melanoma and vitiligo-like leukoderma: an electron microscopic study. Journal of the American Academy of Dermatology 9,696-708.
32. Kosaras, B. & Sidman, R.L. (1996) Phagosome number and distribution in retinal pigment epithelial cells of vitiligo mutant mice. Experimental Eye Research 63,151-158.
33. Lamont, S.J. & Smyth, J.R. Jr (1981) Effect of bursectomy on development of a spontaneous postnatal amelanosis. Clinical Immunology and Immunopathology 21,407-411.
34. Lamont, S.J. & Smyth, J.R. Jr (1984) Effect of selection for delayed amelanosis on immune response in chickens. 1. Antibody production. Poultry Science 63,436-439.
35. Lamont, S.J., Boissy, R.E. & Smyth, J.R. Jr (1982) Humoral immune response and expression of spontaneous postnatal amelanosis in DAM line chickens. Immunology Communications 11,121-127.
36. Lamoreux, M.L., Gerrity, L. & Boissy, R.E. (1987) Animal Models of Human Disease: Vitiligo. Comparative Pathology Bulletin XIX, 2, May.
37. Lamoreux, M.L., Boissy, R.E., Womack, J.E. & Nordlund, J.J. (1992) The vit gene maps to the mi (microphthalmia) locus of the laboratory mouse. Journal of Heredity 83,435-439.
38. Lamoreux, M.L., Zhou, B.K., Rosemblat, S. & Orlow, S.J. (1995) The pinkeyed-dilution protein and the eumelanin/pheomelanin switch: in support of a unifying hypothesis. Pigment Cell Research 8,263-270.
39. Le Poole, I.C., Das, P.K., van den Wijngaard, R.M., Bos, J.D. & Westerhof, W. (1993)Review of the etiopathomechanism of vitiligo: a convergence theory. Experimental Dermatology 2,145-153.
40. Lerner, A.B. & Cage, G.W. (1973) Melanomas in Horses. Yale Journal of Biology and Medicine 46,646-649.
41. Lerner, A.B., Shiohara, T., Boissy, R.E., Jacobson, K.A., Lamoreux, M.L. & Moellmann,G.E. (1986) A possible mouse model for vitiligo. Journal of Investigative Dermatology 87, 299-304.
42. Marklund, L.M., Moller, M.J., Hoyheim, B., Davies, W., Fredholm, M., Juneja, R.K., Mariani, P., Coppieters, W., Ellegren, H. & Andersson, L. (1996) A comprehensive linkage map of the pig based on a wild pig-Large White intercross. Animal Genetics 27, 255-269.
43. Merinsky, O., Shoenfeld, Y., Yecheskel, G., Chaitchik, S., Azizi, E. & Fishman, P. (1994) Vitiligo and melanoma-associated hypopigmentation: a similar appearance but a dif-ferent mechanism. Cancer Immunology Immunotherapy 38,411-416.
44. Misfeldt, M.L. & Grimm, D.G. (1994) Sinclair miniature swine: an animal model of human melanoma. Veterinary Immunology and Immunopathology 43,167-175.
45. Moore, K.J. (1995) Insight into the microphthalmia gene. Trends in Genetics 11,442-448.
46. Morgan, C.D., Measel, J.W. Jr, Amoss, M.S. Jr, Rao, A. & Greene, J.F. Jr (1996)Immunophenotypic characterization of tumor infiltrating lymphocytes and peripheral blood lymphocytes isolated from melanomatous and non-melanomatous Sinclair miniature swine. Veterinary Immunology and Immunopathology 55,189-203.
47. Morse, H.C. Ill, Yetter, R.A., Stimpfling, J.H., Pitts, O.M., Fredrickson, T.N. & Hartley, J.W. (1985) Graying with age in mice: relation to expression of murine leukemia viruses. Cell 41,439-448.
48. Naftzger, C., Takechi, Y., Kohda, H., Hara, I., Vijayasaradhi, S. & Houghton, A.N. (1996) Immune response to a differentiation antigen induced by altered antigen: a study of tumor rejection and autoimmunity. Proceedings of the National Academy of Sciences of the United States of America 93,14809-14814.
49. Nakayama, K., Nakayama, K., Negishi, I., Kuida, K., Sawa, H. & Loh, D.Y. (1994) Targeted disruption of Bcl-2ab in mice: occurrence of gray hair, polycystic kidney disease and lymphocytopenia. Proceedings of the National Academy of Sciences of the United States of America 91,3700-3704.
50. Naughton, G.K., Mahaffey, M. & Bystryn, J.-C. (1986) Antibodies to surface antigens of pigmented cells in animals with vitiligo. Proceedings of the Society for Experimental Biology and Medicine 181,423-426.
51. Nir, 1., Ransom, N. & Smith, S.B. (1995) Ultrastructural features of retinal dystrophy in mutant vitiligo mice. Experimental Eye Research 61,363-377.
52. Nordlund, J.J., Kirkwood, J.M., Forget, B.M., Milton, G., Albert, D.M. & Lerner, A.B.(1983) Vitiligo in patients with metastatic melanoma: a good prognostic sign. Journal of the American Academy of Dermatology 9,689-696.
53. Nordlund, J.J., Csato, M., Babcock, G. et al. (1995) Low ICAM-1 expression in the epidermis of depigmenting C57GL/6J-mivll/mivlt mice: a possible cause of muted contact sensitization. Experimental Dermatology 4,20-29.
54. Nordlund, J.J., Boissy, R.E., Hearing, V.J., King, R.A. & Ortonne, J.-R, eds. (1998). The Pig-mentary System: Physiology and Pathophysiology. Oxford University Press, New York.
55. Norris, D.A., Horikawa, T. & Morell, J.G. (1994) Melanocyte destruction and repopulation in vitiligo. Pigment Cell Research 7,193-203.
56. Oh, Y.-S. & Tomita, T. (1987) Linkage of faded gene to chromosome 6 of the mouse. Experi-mental Animals 36,73-77.
57. Oh, Y.-S., Tomita, T. & Kondo, K. (1986) Faded, a mutation in the KSB strain of mouse which shows age-related pigment change. Experimental Animals 35,131-138.
58. Orlow, S.J., Zhou, B.-K., Chakraborty, A.K., Drucker, M., Pifko-Hirst, S. & Pawelek, J.(1994) High molecular weight forms of tyrosinase and tyrosinase-related proteins: evidence for a melanogenic complex. Journal of Investigative Dermatology 103,196-201.
59. Pardue, S.L., Fite, K.V., Bengston, L., Lamont, S.J., Boyle, M.L. Ill & Smyth, J.R. Jr (1987) Enhanced integumental and ocular amelanosis following the termination of cyclosporine administration. Journal of Investigative Dermatology 88,758-761.
60. Pathak, S. & Amoss, M.S. (1997) Genetic predisposition and specific chromosomal defects associated with Sinclair swine malignant melanoma. International Journal of Oncology 11,53-57.
61. Piedrahita, J.A., Moore, K., Oetama, B., Lee, C.-K., Scales, N., Ramsoondar, J., Bazer, F.W.& Ott, T. (1998) Generation of transgenic porcine chimeras using primordial germ cell- derived colonies. Biology of Reproduction 58,1321-1329.
62. Quevedo, W.C. Jr & Chase, H.B. (1958) An analysis of the light mutation of coat color in mice. Journal of Morphology 102,329-346.
63. Raymond, S.M. & Jackson, I.J. (1995) Requirement for retinal pigmented epithelium in development of the neural retina. Current Biology 5,1286-1295.
64. Rose, N.R. (1994) Avian models of autoimmune disease: lessons from the birds. Poultry Science 73,984-990.
65. Rosenberg, S.A. & White, D.E. (1996) Vitiligo in patients with melanoma. Normal tissue antigens can be targets for cancer immunotherapy. Journal of Immunotherapy with Emphasis on Tumor Immunology 19,81-84.
66. Searle, E.A., Austin, L.M., Boissy, Y.L., Zhao, H., Nordlund, J.J. & Boissy, R.E. (1993)Smyth chicken melanocyte autoantibodies: cross-species recognition, in vivo binding, and plasma membrane reactivity of the antiserum. Pigment Cell Research 6,145-157.
67. Shim, H., Gutierrez-Adan, A., Chen, L.R., BonDurant, R.H., Behboodi, E. & Anderson, G.B. (1997) Isolation of pluripotent stem cells from cultured porcine primordial germ cells. Biology of Reproduction 57,1089-1095.
68. Sidman, R.L. & Neumann, P. (1988) Vitiligo: a new retinal degeneration mutation. Mouse News Letter 81,60.
69. Sidman, R.L., Kosaras, B. & Tang, M. (1996) Pigment epithelial and retinal phenotypes in the vitiligo, mivit, mutant mouse. Investigative Ophthalmology and Visual Science 37, 1097-1115.
70. Smirnakis, S.M., Tang, M. & Sidman, R.L. (1991) Abnormalities of pigment epithelium precede photoreceptor cell degeneration in vitiligo mutant mice. Investigative Ophthalmology and Visual Science 32,1056.
71. Smith, S.B. & Defoe, D.M. (1995) Autoradiographic and biochemical assessment of rod outer segment renewal in the vitiligo (C57BL/6- mi<"mv") mouse model of retinal degeneration. Experimental Eye Research 60,91-96.
72. Smith, S.B. & Hamasaki, D.I. (1994) Electroretinographic study of the C57BL/6- milmi
73. Smith, S.B. & Wiggert, B.N. (1995) Morphological and biochemical studies of the retinal degeneration in the vitiligo mouse. A model with perturbed retinoid metabolism. In: Degenerative Diseases of the Retina (ed. R.E.Anderson et al.), pp. 155-162, Plenum Press, New York.
74. Smith, S.B., Zhou, B.K. & Orlow, S.J. (1988) Expression of tyrosinase and the tyrosinase related proteins in the MitL (vitiligo) mouse eye-implications for the function of the microphthalmia transcription factor (Mitf). Experimental Eye Research 66,403-410.
75. Smith, S.B., Cope, B.K., McCoy, J.R., McCool, D.J. & Defoe, D.M. (1994) Reduction of phagosomes in the vitiligo (C57BL/6- minimi') mouse model of retinal degeneration. Investigative Ophthalmology and Visual Science 35,3625-3632.
76. Smith, S.B., Bora, N., McCool, D., Kutty, G., Wong, P., Kutty, R.K. & Wiggert, B. (1995) Photoreceptor cells in the vitiligo mouse die by apoptosis. TRPM-2/Clusterin expression is increased in the neural retina and in the retinal pigment epithelium. Investigative Ophthalmology and Visual Science 36,2193-2201.
77. Smith, S.B., Brodjian, S., Desai, S. & Sarthy, V. (1997) Glial fibrillary acidic protein (GFAP) is synthesized in the early stages of the photoreceptor cell degeneration of the mi*i/mi™ (vitiligo) mouse. Experimental Eye Research 64,645-650.
78. Smith, S.B., McClung, J., Wiggert, B.N. & Nir, I. (1998) Delayed rhodopsin regeneration and altered distribution of interphotoreceptor retinoid binding protein (IRBP) in the mi''"/mi'" (vitiligo) mouse. Journal of Neurocytology 26,605-613.
79. Smyth, J.R. Jr (1989) the Smyth chicken: model of autoimmune amelanosis. Critical Revieivs in Poultry Science 2,1-9.
80. Smyth, J.R. Jr (1990) Genetics of plumage, skin and eye pigmentation in chickens. In: Poultry Breeding and Genetics (ed. R.D.Crawford), pp. 109-167, Elsevier, Amsterdam.
81. Smyth, J.R. Jr, Boissy, R.E. & Fite, K.V. (1981) the DAM chicken: a model for spontaneous postnatal cutaneous and ocular amelanosis. Journal of Heredity 72,150-156.
82. Song, Y., Connor, E., Li, Y., Zorovich, B., Balducci, P. & Maclaren, N. (1994) The role of tyrosinase in autoimmune vitiligo. Lancet 344,1049-1052.
83. Sreekuman, G.P., Smyth, J.R. Jr, Bhogle, A.S., Lakshmanan, M. & Ponce de Leon, F.A.85. (1995) Incidence of avian leukosis in the Smyth line model for autoimmune vitiligo. Poultry Science 74 (Suppl. 2), 25.
84. Sreekuman, G.P., Smyth, J.R. Jr & Ponce de Leon, F.A. (1997) Genetic and molecular linkage analysis of the Smyth line chicken model for autoimmune human vitiligo. Pigment Cell Research 10,116.
85. Steel, K.P. (1981) Mouse News Letter 64 (76), 1981.
86. Tang, M., Ruiz, M., Kosaras, B. & Sidman, R.L. (1996) Increased cell genesis in retinal pigment epithelium of perinatal Vitiligo mutant mice. Investigative Ophthalmology and Visual Science 37,1116-1124.
87. Tang, M., Pawlyk, B.S., Kosaras, B., Berson, E.L. & Sidman, R.L. (1997) ERG abnormalities in relation to histopathologic findings in vitiligo mutant mice. Experimental Eye Research 65,215-222.
88. Veis, D.J., Sorenson, C.M., Shutter, J.R. & Korsmeyer, S.J. (1993) Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys and hypopigmented hair. Cell 75,229-240.
89. Wang, R.-F., Parkhurst, M.R., Kawakami, Y., Robbins, P.F. & Rosenberg, S.A. (1996) Utilization of an alternative open reading frame of a normal gene in generating a novel human cancer antigen. Journal of Experimental Medicine 183,1131-1140.
90. Willier, B.H. & Rawles, M.E. (1940) The control of feather color pattern by melanophores grafted from one embryo to another of a different breed of fowl. Physiological Zoology 13,177-199.
91. Yamamura, K., Kamada, S., Ito, S., Nakagawa, K., Ichihashi, M. & Tsujimoto, Y. (1996) Accelerated disappearance of melanocytes in BCL-2-deficient mice. Cancer Research 56,3546-3550.