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Volumn 16, Issue 18, 2005, Pages 2057-2060

Glutamate metabolism in epilepsy: 13C-magnetic resonance spectroscopy observation in the human brain

Author keywords

13C MRS; Epilepsy; Glucose metabolism; Glutamate; Glutamine; Magnetic resonance spectroscopy

Indexed keywords

GLUTAMIC ACID;

EID: 28844466986     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200512190-00018     Document Type: Article
Times cited : (13)

References (25)
  • 2
    • 0027262604 scopus 로고
    • Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain
    • During MJ, Spencer DD. Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain. Lancet 1993; 341:1607-1610.
    • (1993) Lancet , vol.341 , pp. 1607-1610
    • During, M.J.1    Spencer, D.D.2
  • 3
    • 0033848981 scopus 로고    scopus 로고
    • In vivo measurements of glutamine + glutamate (Glx) and N-acetyl aspartate (NAA) levels in human partial epilepsy
    • Savic I, Thomas AM, Ke Y, Curran J, Fried I, Engel J Jr. In vivo measurements of glutamine + glutamate (Glx) and N-acetyl aspartate (NAA) levels in human partial epilepsy. Acta Neurol Scand 2000; 102:179-188.
    • (2000) Acta Neurol Scand , vol.102 , pp. 179-188
    • Savic, I.1    Thomas, A.M.2    Ke, Y.3    Curran, J.4    Fried, I.5    Engel Jr., J.6
  • 4
    • 0141924732 scopus 로고    scopus 로고
    • Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy
    • Simister RJ, McLean MA, Barker GJ, Duncan JS. Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy. Neurology 2003; 61:897-902.
    • (2003) Neurology , vol.61 , pp. 897-902
    • Simister, R.J.1    McLean, M.A.2    Barker, G.J.3    Duncan, J.S.4
  • 5
    • 0029114107 scopus 로고
    • Glutamate transporters in glial plasma membranes: Highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry
    • Chaudhry FA, Lehre KP, van Lockeren Campagne M, Ottersen OP, Danbolt NC, Storm-Mathisen J. Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 1995; 15:711-720.
    • (1995) Neuron , vol.15 , pp. 711-720
    • Chaudhry, F.A.1    Lehre, K.P.2    Van Lockeren Campagne, M.3    Ottersen, O.P.4    Danbolt, N.C.5    Storm-Mathisen, J.6
  • 6
    • 0034256927 scopus 로고    scopus 로고
    • Functional integration of the transport of ammonium, glutamate, and glutamine in astrocytes
    • Brookes N. Functional integration of the transport of ammonium, glutamate, and glutamine in astrocytes. Neurochem Int 2000; 37:121-129.
    • (2000) Neurochem Int , vol.37 , pp. 121-129
    • Brookes, N.1
  • 9
    • 0034257070 scopus 로고    scopus 로고
    • Neuronal-astrocytic and cytosolic-mitochondrial metabolite trafficking during brain activation, hyperammonemia and energy deprivation
    • Hertz L, Yu ACH, Kala G, Schousboe A. Neuronal-astrocytic and cytosolic-mitochondrial metabolite trafficking during brain activation, hyperammonemia and energy deprivation. Neurochem Int 2000; 37:83-102.
    • (2000) Neurochem Int , vol.37 , pp. 83-102
    • Hertz, L.1    Yu, A.C.H.2    Kala, G.3    Schousboe, A.4
  • 10
    • 0029564128 scopus 로고
    • 13C-glucose uptake and metabolism: Present status
    • 13C-glucose uptake and metabolism: present status. Magn Reson Imag 1995; 13:1213-1221.
    • (1995) Magn Reson Imag , vol.13 , pp. 1213-1221
    • Van Zijl, P.C.M.1    Rothman, D.2
  • 11
    • 14844303354 scopus 로고    scopus 로고
    • Carbon 13-labeled magnetic resonance spectroscopy observation of cerebral glucose metabolism: Metabolism in MELAS: case report
    • Otsuki T, Kanamatsu T, Tsukada Y, Goto Y, Okamoto K, Watanabe H. Carbon 13-labeled magnetic resonance spectroscopy observation of cerebral glucose metabolism: metabolism in MELAS: case report. Arch Neurol 2005; 62:485-487.
    • (2005) Arch Neurol , vol.62 , pp. 485-487
    • Otsuki, T.1    Kanamatsu, T.2    Tsukada, Y.3    Goto, Y.4    Okamoto, K.5    Watanabe, H.6
  • 14
    • 0037310504 scopus 로고    scopus 로고
    • A comparison of (13)C NMR measurements of the rates of glutamine synthesis and the tricarboxylic acid cycle during oral and intravenous administration of [1-(13)C]glucose
    • Mason GF, Falk Petersen K, de Graaf RA, Kanamatsu T, Otsuki T, Shulman GI, et al. A comparison of (13)C NMR measurements of the rates of glutamine synthesis and the tricarboxylic acid cycle during oral and intravenous administration of [1-(13)C]glucose. Brain Res Brain Res Protoc 2003; 10:181-190.
    • (2003) Brain Res Brain Res Protoc , vol.10 , pp. 181-190
    • Mason, G.F.1    Falk Petersen, K.2    De Graaf, R.A.3    Kanamatsu, T.4    Otsuki, T.5    Shulman, G.I.6
  • 15
    • 0028798036 scopus 로고
    • Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR
    • Mason GF, Gruetter R, Rothman DL, Behar KL, Shulman RG, Novotny EJ. Simultaneous determination of the rates of the TCA cycle, glucose utilization, alpha-ketoglutarate/glutamate exchange, and glutamine synthesis in human brain by NMR. J Cereb Blood Flow Metab 1995; 15:12-25.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 12-25
    • Mason, G.F.1    Gruetter, R.2    Rothman, D.L.3    Behar, K.L.4    Shulman, R.G.5    Novotny, E.J.6
  • 17
    • 0034066220 scopus 로고    scopus 로고
    • Human brain glucose metabolism mapping using multislice 2D (1)H-(13)C correlation HSQC spectroscopy
    • Watanabe H, Umeda M, Ishihara Y, Okamoto K, Oshio K, Kanamatsu T, et al. Human brain glucose metabolism mapping using multislice 2D (1)H-(13)C correlation HSQC spectroscopy. Magn Reson Med 2000; 43:525-533.
    • (2000) Magn Reson Med , vol.43 , pp. 525-533
    • Watanabe, H.1    Umeda, M.2    Ishihara, Y.3    Okamoto, K.4    Oshio, K.5    Kanamatsu, T.6
  • 18
    • 14844330953 scopus 로고    scopus 로고
    • Simple quantitation of proton spectra acquired via phased array coil using tissue water as an internal reference
    • Watanabe H, Okamoto K, Oda M, Kanamatsu T, Tsukada Y, Otsuki T. Simple quantitation of proton spectra acquired via phased array coil using tissue water as an internal reference. Proc Intl Soc Magn Reson Med 2002; 10:2513.
    • (2002) Proc Intl Soc Magn Reson Med , vol.10 , pp. 2513
    • Watanabe, H.1    Okamoto, K.2    Oda, M.3    Kanamatsu, T.4    Tsukada, Y.5    Otsuki, T.6
  • 20
    • 0037210203 scopus 로고    scopus 로고
    • Glial-neuronal interactions following kainite injection in rats
    • Qu H, Eloqayli H, Muller B, Aasly J, Sonnewald U. Glial-neuronal interactions following kainite injection in rats. Neurochem Int 2003; 42:101-106.
    • (2003) Neurochem Int , vol.42 , pp. 101-106
    • Qu, H.1    Eloqayli, H.2    Muller, B.3    Aasly, J.4    Sonnewald, U.5
  • 21
    • 0036197196 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy in epilepsy: Clinical issues
    • Cendes F, Knowlton RC, Novotny E, Min L, Antel S, Sawrie S, et al. Magnetic resonance spectroscopy in epilepsy: clinical issues. Epilepsia 2002; 43 (Suppl 1):32-39.
    • (2002) Epilepsia , vol.43 , Issue.1 SUPPL. , pp. 32-39
    • Cendes, F.1    Knowlton, R.C.2    Novotny, E.3    Min, L.4    Antel, S.5    Sawrie, S.6
  • 22
    • 0030483254 scopus 로고    scopus 로고
    • Low brain GABA level is associated with poor seizure control
    • Petroff OA, Rothman DL, Behar KL, Mattson RH. Low brain GABA level is associated with poor seizure control. Ann Neurol 1996; 40:908-911.
    • (1996) Ann Neurol , vol.40 , pp. 908-911
    • Petroff, O.A.1    Rothman, D.L.2    Behar, K.L.3    Mattson, R.H.4
  • 24
    • 0015523529 scopus 로고
    • Close correlation between changing content of specific amino acids in epileptic cortex of cats, and severity of epilepsy
    • Van Gelder NM, Courtois A. Close correlation between changing content of specific amino acids in epileptic cortex of cats, and severity of epilepsy. Brain Res 1972; 43:477-484.
    • (1972) Brain Res , vol.43 , pp. 477-484
    • Van Gelder, N.M.1    Courtois, A.2
  • 25
    • 0036197933 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopic studies of neurotransmitters and energy metabolism in epilepsy
    • Petroff OA, Pan JW, Rothman DL. Magnetic resonance spectroscopic studies of neurotransmitters and energy metabolism in epilepsy. Epilepsia 2002; 43 (Suppl 1):40-50.
    • (2002) Epilepsia , vol.43 , Issue.1 SUPPL. , pp. 40-50
    • Petroff, O.A.1    Pan, J.W.2    Rothman, D.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.