Hsp70 expression and free radical release after exposure to non-thermal radio-frequency electromagnetic fields and ultrafine particles in human Mono Mac 6 cells

Toxicology Letters

Volumn 161, Issue 1, 2006, Pages 73-82

  Simko M ^a   Hartwig, C ^a   Lantow, M ^a   Lupke, M ^a   Mattsson, M O ^b   Rahman, Q ^c   Rollwitz, J ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b ÖREBRO UNIVERSITY   (Sweden)

^c CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Free radicals; Hsp70; Immune relevant cells; RF EMF; UFP

Indexed keywords

ANION; FREE RADICAL; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; SUPEROXIDE;

ABSORPTION; ARTICLE; ATTENTION; CELL LINE; CHRONOTHERAPY; COMBUSTION; ELECTROMAGNETIC FIELD; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; MOBILE PHONE; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOFREQUENCY; STRESS;

BLOTTING, WESTERN; CELL LINE, TUMOR; CYTOCHROMES C; ELECTROMAGNETIC FIELDS; FLOW CYTOMETRY; FREE RADICALS; HEAT; HSP70 HEAT-SHOCK PROTEINS; HUMANS; PARTICLE SIZE; PHAGOCYTOSIS; RADIO WAVES; SUPEROXIDES; TIME FACTORS;

EID: 28844435661     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2005.08.005     Document Type: Article

References (46)

1. D.S. Abballa, A. Campa, and H.P. Monteiro Low density lipoprotein oxidation by stimulated neutrophils and ferritin Atherosclerosis 97 1992 149 159
2. B.N. Ames, M.K. Shigenaga, and T.M. Hagen Oxidants, antioxidants, and the degenerative diseases of aging Proc. Natl. Acad. Sci. 90 1993 7915 7922
3. K.B. Beckman, and B.N. Ames The free radical theory of aging matures Physiol. Rev. 78 1998 547 581
4. I. Beck-Speier, N. Dayal, E. Karg, K.L. Maier, G. Schumann, H. Schulz, M. Semmler, S. Takenaka, K. Stettmaier, W. Bors, A. Ghio, J.M. Samet, and J. Heyder Oxidative stress and lipid mediators induced in alveolar macrophages by ultrafine particles Free Radic. Biol. Med. 38 2005 1080 1092
5. D.M. Brown, V. Stone, P. Findlay, W. MacNee, and K. Donaldson Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components Occup. Environ. Med. 57 2000 685 691
6. E. Cadenas, and H. Sies Oxidative stress: excited oxygen species and enzyme activity Adv. Enzyme Regul. 23 1985 217 237
7. I.A. Cotgreave Biological stress responses to radio frequency electromagnetic radiation: are mobile phones really so (heat) shocking? Arch. Biochem. Biophys. 435 2005 227 240
8. D. de Pomerai, C. Daniells, H. David, J. Allan, I. Duce, M. Mutwakil, D. Thomas, P. Sewell, J. Tattersall, D. Jones, and P. Candido Non-thermal heat-shock response to microwaves Nature 405 2000 417 418
9. Dockery, D.W., Pope III, C.A., Xu, X., Spengler, J.D., Ware, J.H., Fay, M.E., Ferris Jr., B.G., Speizer, F.E., 1995. An association between air pollution and mortality. In: Pope III, C.A., Thun, M.J., Namboodiri, M.M., Dockery, D.W., Evans, J.S., Speizer, F.E., Heath Jr., C.W. (Eds.), Particulate Air Pollution as a Predictor of Mortality in a Prospective Study of U.S. Adults. Am. J. Respir. Crit. Care Med. 151, 669-674.
10. K. Donaldson, V. Stone, P.J.A. Borm, L.A. Jimenez, P.S. Gilmour, R.P.F. Schins, A.M. Knaapen, I. Rahman, S.P. Faux, D.M. Brown, and W. MacNee Oxidative stress and calcium signaling in the adverse effects of environmental particles (PM10) Free Radic. Biol. Med. 34 2003 1369 1382
11. M. Donnellan, D.R. McKenzie, and P.W. French Effects of exposure to electromagnetic radiation at 835 MHz on growth, morphology and secretory characteristics of a mast cell analogue, RBL-2H3 Cell Biol. Int. 21 1997 427 439
12. W. Dröge Free radicals in the physiological control of cell function Physiol. Rev. 82 2002 47 95
13. P.W. French, M. Donnellan, and D.R. McKenzie Electromagnetic radiation at 835 MHz changes the morphology and inhibits proliferation of a human astrocytoma cell line Bioelectrochem. Bioenerg. 43 1997 13 18
14. P.W. French, R. Penny, J.A. Laurence, and D.R. McKenzie Mobile phones, heat shock proteins and cancer Differentiation 67 2001 93 97
15. K. Frenkel, W. Chrzan, G.W. Troll, J. Teebor, and J. Steinberg Radiation-like modification of bases in DNA exposed to tumor promoter-activated polymorphonuclear leukocytes Cancer Res. 46 1986 5533 5540
16. T. Gotoh, K. Terada, and M. Mori hsp70-DnaJ chaperone pairs prevent nitric oxide-mediated apoptosis in RAW 264.7 macrophages Cell Death Differ. 8 2001 357 366
17. Y. Inoue, Y. Sato, M. Nishimura, M. Seguchi, Y. Zaitsu, K. Yamada, and Y. Oka. Heat-induced drug resistance is associated with increased expression of Bcl-2 in HL60 Anticancer Res. 19 1999 3989 3992
18. C.J. Johnston, J.N. Finkelstein, R. Gelein, R. Baggs, and G. Oberdoerster Characterization of the early pulmonary inflammatory response associated with PTFE fume exposure Toxicol. Appl. Pharmacol. 140 1996 154 163
19. C. Jolly, and R.I. Morimoto Role of the heat shock response and molecular chaperones in oncogenesis and cell death J. Natl. Cancer Inst. 92 2000 1564 1572
20. S. Kwee, P. Raskmark, and S. Velizarov Changes in cellular proteins due to environmental non-ionizing radiation. 1. Heat shock proteins. Electro Magnetobiol. 20 2001 165 176
21. D. Leszczynski, S. Joenvaara, J. Reivinen, and R. Kuokka Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: molecular mechanism for cancer- and blood-brain barrier-related effects Differentiation 70 2002 120 129
22. X.Y. Li, D. Brown, S. Smith, W. MacNee, and K. Donaldson Short-term inflammatory responses following intratracheal instillation of fine and ultrafine carbon black in rats Inhal. Toxicol. 11 1999 709 731
23. X.Y. Li, P.S. Gilmour, K. Donaldson, and W. MacNee In vivo and in vitro proinflammatory effects of particulate air pollution (PM10) Environ. Health Perspect. 105 Suppl. 5 1997 1279 1283
24. M. Lupke, J. Rollwitz, and M. Simkó Cell activating capacity of 50 Hz magnetic fields to release reactive oxygen intermediates in human umbilical cord blood-derived monocytes and in Mono Mac 6 cells Free Radic. Res. 38 2004 985 993
25. W. MacNee, and K. Donaldson How can ultrafine particles be responsible for increased mortality? Monaldi Arch Chest Dis. 55 2000 135 139
26. L.J. Marnett Oxyradicals and DNA damage Carcinogenesis 21 2000 361 370
27. Y. Morel, and R. Barouki Repression of gene expression by oxidative stress Biochem. J. 342 1999 481 496
28. J.E. Moulder, L.S. Erdreich, R.S. Malyapa, J. Merritt, W.F. Pickard, and Vijayalaxmi Cell phones and cancer: what is the evidence for a connection? Radiat. Res. 151 1999 513 531
29. Y.M. Moustafa, R.M. Moustafa, A. Belacy, S.H. Abou-El-Ela, and F.M. Ali Effects of acute exposure to the radiofrequency fields of cellular phones on plasma lipid peroxide and antioxidase activities in human erythrocytes J. Pharm. Biomed. Anal. 26 2001 605 608
30. G. Oberdoerster, J. Ferin, R. Gelein, S.C. Soderholm, and J. Finkelstein Role of the alveolar macrophage in lung injury: studies with ultrafine particles Environ. Health Perspect. 97 1992 193 199
31. C.A. Pope, M.J. Thun, M.M. Namboodiri, D.W. Dockery, J.S. Evans, F.E. Speizer, and C.W. Heath Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults Am. J. Respir. Crit. Care Med. 151 1995 669 674
32. L. Ramage, and K. Guy Expression of C-reactive protein and heat-shock protein-70 in the lung epithelial cell line A549, in response to PM10 exposure Inhal. Toxicol. 16 2004 447 452
33. J. Rollwitz, M. Lupke, and M. Simkó Fifty-hertz magnetic fields induce free radical formation in mouse bone marrow-derived promonocytes and macrophages Biochim. Biophys. Acta 1674 2004 231 238
34. I. Schraufstatter, P.A. Hyslop, J.H. Jackson, and C.G. Cochrane Oxidant-induced DNA damage of target cells J. Clin. Invest. 82 1988 1040 1050
35. J. Schuderer, T. Samaras, W. Oesch, D. Spät, and N. Kuster High peak SAR exposure unit with tight exposure and environmental control for in vitro experiments at 1800 MHz. IEEE Trans. Microwave Theory and Tech., accepted 2004 accepted
36. E. Shacter, E.J. Beecham, J.M. Covey, K.W. Kohn, and M. Potter Activated neutrophils induce prolonged DNA damage in neighboring cells Carcinogenesis 12 1988 2297 2304
37. M. Simkó, S. Droste, R. Kriehuber, and D.G. Weiss Stimulation of phagocytosis and free radical production in murine macrophages by 50 Hz electromagnetic fields Eur. J. Cell. Biol. 80 2001 562 566
38. V. Stone, J. Shaw, D.M. Brown, W. MacNee, S.P. Faux, and K. Donaldson The role of oxidative stress in the prolonged inhibitory effect of ultrafine carbon black on epithelial cell function Toxicol. In Vitro 12 1998 649 659
39. V. Stone, M. Tuinman, J.E. Vamvakopoulos, J. Shaw, D. Brown, S. Petterson, S.P. Faux, P. Borm, W. MacNee, F. Michaelangeli, and K. Donaldson Increased calcium influx in a monocytic cell line on exposure to ultrafine carbon black Eur. Respir. J. 15 2000 297 303
40. S. Takenaka, E. Karg, W. Möller, C. Roth, A. Ziesenis, U. Heinzmann, P. Schramel, and J. Heyder A morphologic study on the fate of ultrafine silver particles: Distribution pattern of phagocytized metallic silver in vitro and in vivo Inhal. Toxicol. 12 2000 291 299
41. T.H. Tuch, P. Brand, H.E. Wichmann, and J. Heyder Variation of particle number and mass concentration in various size ranges of ambient aerosols in eastern Germany Atmos. Environ. 31 1997 4187 4193
42. S. Velizarov, S. Kwee, and P. Raskmark The effects of radiofrequency fields on cell proliferation are non-thermal Bioelectrochem. Bioenerg. 48 1999 177 180
43. Vijayalaxmi, and G. Obe Controversial cytogenetic observations in mammalian somatic cells exposed to radiofrequency radiation Radiat. Res. 162 2004 481 496
44. S.J. Weiss The role of superoxide in the destruction of erythrocyte targets by human neutrophils J. Biol. Chem. 255 1980 9912 9917
45. H. Wiseman, and B. Halliwell Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer Biochem. J. 313 1996 17 29
46. Q. Zhang, Y. Kusaka, K. Sato, K. Nakakuki, N. Kohyama, and K. Donaldson Differences in the extent of inflammation caused by intratracheal exposure to three ultrafine metals: role of free radicals J. Toxicol. Environ. Health 53 1998 423 438