-
1
-
-
0022970945
-
Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
-
Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986; 74; 1124-1136
-
(1986)
Circulation
, vol.74
, pp. 1124-1136
-
-
Murry, C.E.1
Jennings, R.B.2
Reimer, K.A.3
-
2
-
-
0028144647
-
Induction of 27-kDa heat shock protein following cerebral ischemia in a rat model of ischemic tolerance
-
Kato H, Liu Y, Kogure K, Kato K. Induction of 27-kDa heat shock protein following cerebral ischemia in a rat model of ischemic tolerance. Brain Res 1994; 634: 235-244
-
(1994)
Brain Res
, vol.634
, pp. 235-244
-
-
Kato, H.1
Liu, Y.2
Kogure, K.3
Kato, K.4
-
3
-
-
0031059212
-
Susceptibility of human proximal tubular cells to hypoxia: Effect of hypoxic preconditioning and comparison to glomerular cells
-
Turman MA, Bates CM. Susceptibility of human proximal tubular cells to hypoxia: effect of hypoxic preconditioning and comparison to glomerular cells. Ren Fail 1997; 19: 47-60
-
(1997)
Ren Fail
, vol.19
, pp. 47-60
-
-
Turman, M.A.1
Bates, C.M.2
-
4
-
-
12644265396
-
Ischemic preconditioning of the liver in rats: Implications of heat shock protein induction to increase tolerance of ischemia-reperfusion injury
-
Kume M, Yamamoto Y, Saad S, Gomi T, Kimoto S, Shimabukuro T, Yagi T, Nakagami M, Takada Y, Morimoto T, Yamaoka Y. Ischemic preconditioning of the liver in rats: implications of heat shock protein induction to increase tolerance of ischemia-reperfusion injury. J Lab Clin Med 1996; 128: 251-258
-
(1996)
J Lab Clin Med
, vol.128
, pp. 251-258
-
-
Kume, M.1
Yamamoto, Y.2
Saad, S.3
Gomi, T.4
Kimoto, S.5
Shimabukuro, T.6
Yagi, T.7
Nakagami, M.8
Takada, Y.9
Morimoto, T.10
Yamaoka, Y.11
-
5
-
-
0026460101
-
Augmentation of skeletal muscle survival in the latissimus dorsi porcine model using acute ischemic preconditioning
-
Mounsey RA, Pang CY, Boyd JB, Forrest C. Augmentation of skeletal muscle survival in the latissimus dorsi porcine model using acute ischemic preconditioning. J Otolaryngol 1992; 21: 315-320
-
(1992)
J Otolaryngol
, vol.21
, pp. 315-320
-
-
Mounsey, R.A.1
Pang, C.Y.2
Boyd, J.B.3
Forrest, C.4
-
6
-
-
0035929228
-
Ischemic preconditioning, the most effective gastroprotective intervention: Involvement of prostaglandins, nitric oxide, adenosine and sensory nerves
-
Pajdo R, Brzozowski T, Konturek PC, Kwiecien S, Konturek SJ, Sliwowski Z, Pawlik M, Ptak A, Drozdowicz D, Hahn EG. Ischemic preconditioning, the most effective gastroprotective intervention: involvement of prostaglandins, nitric oxide, adenosine and sensory nerves. Eur J Pharmacol 2001; 427: 263-276
-
(2001)
Eur J Pharmacol
, vol.427
, pp. 263-276
-
-
Pajdo, R.1
Brzozowski, T.2
Konturek, P.C.3
Kwiecien, S.4
Konturek, S.J.5
Sliwowski, Z.6
Pawlik, M.7
Ptak, A.8
Drozdowicz, D.9
Hahn, E.G.10
-
7
-
-
0043208961
-
Ischemic preconditioning reduces the severity of ischemia/reperfusion-induced pancreatitis
-
Dembiñski A, Warzecha Z, Ceranowicz P, Tomaszewska R, Dembinski M, Pabiañczyk M, Stachura J, Konturek SJ. Ischemic preconditioning reduces the severity of ischemia/reperfusion-induced pancreatitis. Eur J Pharmacol 2003; 473: 207-216
-
(2003)
Eur J Pharmacol
, vol.473
, pp. 207-216
-
-
Dembiñski, A.1
Warzecha, Z.2
Ceranowicz, P.3
Tomaszewska, R.4
Dembinski, M.5
Pabiañczyk, M.6
Stachura, J.7
Konturek, S.J.8
-
8
-
-
0030479496
-
Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and 2
-
Smith WL, Garavito RM, DeWitt DL. Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and 2. J Biol Chem 1996; 271: 33157-33160
-
(1996)
J Biol Chem
, vol.271
, pp. 33157-33160
-
-
Smith, W.L.1
Garavito, R.M.2
DeWitt, D.L.3
-
9
-
-
0034747981
-
Role of cyclooxygenase isoforms in gastric mucosal defence
-
Peskar BM. Role of cyclooxygenase isoforms in gastric mucosal defence. J Physiol Paris 2001; 95: 3-9
-
(2001)
J Physiol Paris
, vol.95
, pp. 3-9
-
-
Peskar, B.M.1
-
10
-
-
0019366413
-
Role of prostaglandins in the formation of aspirin-induced gastric ulcers
-
Konturek SJ, Piastucki I, Brzozowski T, Radecki T, Dembinska-Kiec A, Zmuda A, Gryglewski R. Role of prostaglandins in the formation of aspirin-induced gastric ulcers. Gastroenterology 1981; 80: 4-9
-
(1981)
Gastroenterology
, vol.80
, pp. 4-9
-
-
Konturek, S.J.1
Piastucki, I.2
Brzozowski, T.3
Radecki, T.4
Dembinska-Kiec, A.5
Zmuda, A.6
Gryglewski, R.7
-
11
-
-
0024489353
-
Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin
-
Wang JY, Yamasaki S, Takeuchi K, Okabe S. Delayed healing of acetic acid-induced gastric ulcers in rats by indomethacin. Gastroenterology 1989; 96: 393-402
-
(1989)
Gastroenterology
, vol.96
, pp. 393-402
-
-
Wang, J.Y.1
Yamasaki, S.2
Takeuchi, K.3
Okabe, S.4
-
12
-
-
0031052116
-
Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice
-
Mizuno H, Sakamoto C, Matsuda K, Wada K, Uchida T, Noguchi H, Akamatsu T, Kasuga M. Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology 1997; 112: 387-397
-
(1997)
Gastroenterology
, vol.112
, pp. 387-397
-
-
Mizuno, H.1
Sakamoto, C.2
Matsuda, K.3
Wada, K.4
Uchida, T.5
Noguchi, H.6
Akamatsu, T.7
Kasuga, M.8
-
13
-
-
0036839741
-
Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury
-
Song AM, Bhagat L, Singh VP, van Acker GGD, Steer ML, Saluja AK. Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury. Am J Physiol Gastrointest Liver Physiol 2002; 283: G1166-1174
-
(2002)
Am J Physiol Gastrointest Liver Physiol
, vol.283
-
-
Song, A.M.1
Bhagat, L.2
Singh, V.P.3
van Acker, G.G.D.4
Steer, M.L.5
Saluja, A.K.6
-
14
-
-
0036788339
-
Cyclooxygenase-2 gene disruption attenuates the severity of acute pancreatitis and pancreatitis-associated lung injury
-
Ethridge RT, Chung DH, Slogoff M, Ehlers RA, Hellmich MR, Rajaraman S, Saito H, Uchida T, Evers BM. Cyclooxygenase-2 gene disruption attenuates the severity of acute pancreatitis and pancreatitis-associated lung injury. Gastroenterology 2002; 123: 1311-1322
-
(2002)
Gastroenterology
, vol.123
, pp. 1311-1322
-
-
Ethridge, R.T.1
Chung, D.H.2
Slogoff, M.3
Ehlers, R.A.4
Hellmich, M.R.5
Rajaraman, S.6
Saito, H.7
Uchida, T.8
Evers, B.M.9
-
15
-
-
1642482293
-
Inhibition of cyclooxygenase-2 reduces the protective effect of hepatocyte growth factor in experimental pancreatitis
-
Warzecha Z, Dembinski A, Ceranowicz P, Konturek SJ, Tomaszewska R, Stachura J, Nakamura T, Konturek PC. Inhibition of cyclooxygenase-2 reduces the protective effect of hepatocyte growth factor in experimental pancreatitis. Eur J Pharmacol 2004; 486: 107-119
-
(2004)
Eur J Pharmacol
, vol.486
, pp. 107-119
-
-
Warzecha, Z.1
Dembinski, A.2
Ceranowicz, P.3
Konturek, S.J.4
Tomaszewska, R.5
Stachura, J.6
Nakamura, T.7
Konturek, P.C.8
-
17
-
-
0029809552
-
Hyperthermia induces heat shock protein expression and protection against cerulein-induced pancreatitis in rats
-
Wagner AC, Weber H, Jonas L, Nizze H, Strowski M, Fiedler F, Printz H, Steffen H, Goke B. Hyperthermia induces heat shock protein expression and protection against cerulein-induced pancreatitis in rats. Gastroenterology 1996; 111: 1333-1342
-
(1996)
Gastroenterology
, vol.111
, pp. 1333-1342
-
-
Wagner, A.C.1
Weber, H.2
Jonas, L.3
Nizze, H.4
Strowski, M.5
Fiedler, F.6
Printz, H.7
Steffen, H.8
Goke, B.9
-
18
-
-
3242720733
-
Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis
-
Kubisch C, Dimagno MJ, Tietz AB, Welsh MJ, Ernst SA, Brandt-Nedelev B, Diebold J, Wagner AC, Goke B, Williams JA, Schafer C. Overexpression of heat shock protein Hsp27 protects against cerulein-induced pancreatitis. Gastroenterology 2004; 127: 275-286
-
(2004)
Gastroenterology
, vol.127
, pp. 275-286
-
-
Kubisch, C.1
Dimagno, M.J.2
Tietz, A.B.3
Welsh, M.J.4
Ernst, S.A.5
Brandt-Nedelev, B.6
Diebold, J.7
Wagner, A.C.8
Goke, B.9
Williams, J.A.10
Schafer, C.11
-
19
-
-
0036000096
-
Hyperthermia induces multiple pancreatic heat shock proteins and protects against subsequent arginine-induced acute pancreatitis in rats
-
Tashiro M, Ernst SA, Edwards J, Williams JA. Hyperthermia induces multiple pancreatic heat shock proteins and protects against subsequent arginine-induced acute pancreatitis in rats. Digestion 2002; 65: 118-126
-
(2002)
Digestion
, vol.65
, pp. 118-126
-
-
Tashiro, M.1
Ernst, S.A.2
Edwards, J.3
Williams, J.A.4
-
20
-
-
0028218892
-
Nitric oxide in pancreatic secretion and hormone-induced pancreatitis in rats
-
Konturek SJ, Szlachcic A, Dembinski A, Warzecha Z, Jaworek J, Stachura J. Nitric oxide in pancreatic secretion and hormone-induced pancreatitis in rats. Int J Pancreatol 1994; 15: 19-28
-
(1994)
Int J Pancreatol
, vol.15
, pp. 19-28
-
-
Konturek, S.J.1
Szlachcic, A.2
Dembinski, A.3
Warzecha, Z.4
Jaworek, J.5
Stachura, J.6
-
21
-
-
0018508408
-
Serum ribonuclease elevations and pancreatic necrosis in acute pancreatitis
-
Warshaw AL, Lee KH. Serum ribonuclease elevations and pancreatic necrosis in acute pancreatitis. Surgery 1979: 86: 227-234
-
(1979)
Surgery
, vol.86
, pp. 227-234
-
-
Warshaw, A.L.1
Lee, K.H.2
-
22
-
-
11144230487
-
Extract of grapefruit-seed reduces acute pancreatitis induced by ischemia/reperfusion in rats; Possible implication of tissue antioxidants
-
3a B, Naskalski JW. Extract of grapefruit-seed reduces acute pancreatitis induced by ischemia/reperfusion in rats; Possible implication of tissue antioxidants. J Physiol Pharmacol 2004; 55: 799-809
-
(2004)
J Physiol Pharmacol
, vol.55
, pp. 799-809
-
-
Dembinski, A.1
Warzecha, Z.2
Konturek, S.J.3
Ceranowicz, P.4
Dembinski, M.5
Pawlik, W.W.6
Kucenierz-Cabaa, B.7
Naskalski, J.W.8
-
23
-
-
0036908441
-
Influence of leptin administration on the course of acute ischemic pancreatitis
-
Warzecha Z, Dembinski A, Ceranowicz P, Jaworek J, Konturek PC, Dembiñski M, Bilski J, Konturek SJ. Influence of leptin administration on the course of acute ischemic pancreatitis. J Physiol Pharmacol 2002; 53: 775-790
-
(2002)
J Physiol Pharmacol
, vol.53
, pp. 775-790
-
-
Warzecha, Z.1
Dembinski, A.2
Ceranowicz, P.3
Jaworek, J.4
Konturek, P.C.5
Dembiñski, M.6
Bilski, J.7
Konturek, S.J.8
-
24
-
-
0032770794
-
Diagnosis, objective assessment of severity, and management of acute pancreatitis. Santorini consensus conference
-
Dervenis C, Johnson CD, Bassi C, Bradley E, Imrie CW, McMahon MJ, Modlin I. Diagnosis, objective assessment of severity, and management of acute pancreatitis. Santorini consensus conference. Int J Pancreatol 1999; 25: 195-210
-
(1999)
Int J Pancreatol
, vol.25
, pp. 195-210
-
-
Dervenis, C.1
Johnson, C.D.2
Bassi, C.3
Bradley, E.4
Imrie, C.W.5
McMahon, M.J.6
Modlin, I.7
-
25
-
-
0141681374
-
Poly-C specific ribonuclease activity correlates with increased concentrations of IL-6, IL-8 and sTNFR55/sTNFR75 in plasma of patients with acute pancreatitis
-
Naskalski JW, Kuœnierz-Cabaa B, Panek J, Kedra B. Poly-C specific ribonuclease activity correlates with increased concentrations of IL-6, IL-8 and sTNFR55/sTNFR75 in plasma of patients with acute pancreatitis. J Physiol Pharmacol 2003; 54: 439-448
-
(2003)
J Physiol Pharmacol
, vol.54
, pp. 439-448
-
-
Naskalski, J.W.1
Kuœnierz-Cabaa, B.2
Panek, J.3
Kedra, B.4
-
26
-
-
0001563463
-
Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: Early morphological changes during development of experimental pancreatitis
-
Watanabe O, Baccino FM, Steer ML, Meldolesi J. Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis. Am J Physiol 1984; 246: G457-G467
-
(1984)
Am J Physiol
, vol.246
-
-
Watanabe, O.1
Baccino, F.M.2
Steer, M.L.3
Meldolesi, J.4
-
27
-
-
0026786596
-
Role of platelet activating factor in pathogenesis of acute pancreatitis in rats
-
Konturek SJ, Dembinski A, Konturek PJ, Warzecha Z, Jaworek J, Gustaw P, Tomaszewska R, Stachura J. Role of platelet activating factor in pathogenesis of acute pancreatitis in rats. Gut 1992; 33: 1268-1274
-
(1992)
Gut
, vol.33
, pp. 1268-1274
-
-
Konturek, S.J.1
Dembinski, A.2
Konturek, P.J.3
Warzecha, Z.4
Jaworek, J.5
Gustaw, P.6
Tomaszewska, R.7
Stachura, J.8
-
28
-
-
0029736982
-
Adaptation of pancreas to repeated caerulein-induced pancreatitis in rats
-
Dembiñski A, Warzecha Z, Konturek PC, Ceranowicz P, Konturek SJ, Tomaszewska R, Stachura J. Adaptation of pancreas to repeated caerulein-induced pancreatitis in rats. J Physiol Pharmacol 1996; 47: 455-467
-
(1996)
J Physiol Pharmacol
, vol.47
, pp. 455-467
-
-
Dembiñski, A.1
Warzecha, Z.2
Konturek, P.C.3
Ceranowicz, P.4
Konturek, S.J.5
Tomaszewska, R.6
Stachura, J.7
-
29
-
-
0347363709
-
IGF-1 stimulates production of interleukin-10 and inhibits development of caerulein-induced pancreatitis
-
Warzecha Z, Dembinski A, Ceranowicz P, Konturek SJ, Tomaszewska R, Stachura J, Konturek PC. IGF-1 stimulates production of interleukin-10 and inhibits development of caerulein-induced pancreatitis. J Physiol Pharmacol 2003; 54: 575-590
-
(2003)
J Physiol Pharmacol
, vol.54
, pp. 575-590
-
-
Warzecha, Z.1
Dembinski, A.2
Ceranowicz, P.3
Konturek, S.J.4
Tomaszewska, R.5
Stachura, J.6
Konturek, P.C.7
-
30
-
-
0033623791
-
Protective action of lipopolysaccharides in rat caerulein-induced pancreatitis: Role of nitric oxide
-
Jaworek J, Jachimczak B, Tomaszewska R, Konturek PC, Pawlik WW, Sendur R, Hahn EG, Stachura J, Konturek SJ. Protective action of lipopolysaccharides in rat caerulein-induced pancreatitis: role of nitric oxide. Digestion 2000; 62: 1-13
-
(2000)
Digestion
, vol.62
, pp. 1-13
-
-
Jaworek, J.1
Jachimczak, B.2
Tomaszewska, R.3
Konturek, P.C.4
Pawlik, W.W.5
Sendur, R.6
Hahn, E.G.7
Stachura, J.8
Konturek, S.J.9
-
31
-
-
0035715721
-
Effect of sensory nerves and CGRP on the development of caerulein-induced pancreatitis and pancreatic recovery
-
Warzecha Z, Dembinski A, Ceranowicz P, Stachura J, Tomaszewska R, Konturek SJ. Effect of sensory nerves and CGRP on the development of caerulein-induced pancreatitis and pancreatic recovery. J Physiol Pharmacol 2001; 52: 679-704
-
(2001)
J Physiol Pharmacol
, vol.52
, pp. 679-704
-
-
Warzecha, Z.1
Dembinski, A.2
Ceranowicz, P.3
Stachura, J.4
Tomaszewska, R.5
Konturek, S.J.6
-
33
-
-
0030066906
-
Significant elevation of serum human hepatocyte growth factor levels in patients with acute pancreatitis
-
Ueda T, Takeyama Y, Toyokawa A, Kishida S, Yamamoto M, Saitoh Y. Significant elevation of serum human hepatocyte growth factor levels in patients with acute pancreatitis. Pancreas 1996; 12: 76-83
-
(1996)
Pancreas
, vol.12
, pp. 76-83
-
-
Ueda, T.1
Takeyama, Y.2
Toyokawa, A.3
Kishida, S.4
Yamamoto, M.5
Saitoh, Y.6
-
34
-
-
0031045973
-
Hepatocyte growth factor in assessment of acute pancreatitis: Comparison with C-reactive protein and interleukin-6
-
Ueda T, Takeyama Y, Hori Y, Nishikawa J, Yamamoto M, Saitoh Y. Hepatocyte growth factor in assessment of acute pancreatitis: Comparison with C-reactive protein and interleukin-6. J Gastroenterol 1997; 32: 63-70
-
(1997)
J Gastroenterol
, vol.32
, pp. 63-70
-
-
Ueda, T.1
Takeyama, Y.2
Hori, Y.3
Nishikawa, J.4
Yamamoto, M.5
Saitoh, Y.6
-
35
-
-
0033970607
-
Hepatocyte growth factor increases in injured organs and functions as an organotrophic factor in rats with experimental acute pancreatitis
-
Ueda T, Takeyama Y, Hori Y, Shinkai M, Takase K, Goshima M, Yamamoto M, Kuroda Y. Hepatocyte growth factor increases in injured organs and functions as an organotrophic factor in rats with experimental acute pancreatitis. Pancreas 2000; 20: 84-93
-
(2000)
Pancreas
, vol.20
, pp. 84-93
-
-
Ueda, T.1
Takeyama, Y.2
Hori, Y.3
Shinkai, M.4
Takase, K.5
Goshima, M.6
Yamamoto, M.7
Kuroda, Y.8
-
36
-
-
0032894827
-
Hepatocyte growth factor and fibroblast growth factor 2 are overexpressed after cerulein-induced acute pancreatitis
-
Menke A, Yamaguchi H, Giehl K, Adler G. Hepatocyte growth factor and fibroblast growth factor 2 are overexpressed after cerulein-induced acute pancreatitis. Pancreas 1999; 18: 28-33
-
(1999)
Pancreas
, vol.18
, pp. 28-33
-
-
Menke, A.1
Yamaguchi, H.2
Giehl, K.3
Adler, G.4
-
37
-
-
0035955394
-
Hepatocyte growth factor attenuates pancreatic damage in caerulein-induced pancreatitis in rats
-
Warzecha Z, Dembinski A, Konturek PC, Ceranowicz P, Konturek SJ, Tomaszewska R, Schuppan D, Stachura J, Nakamura T. Hepatocyte growth factor attenuates pancreatic damage in caerulein-induced pancreatitis in rats. Eur J Pharmacol 2001; 430: 113-121
-
(2001)
Eur J Pharmacol
, vol.430
, pp. 113-121
-
-
Warzecha, Z.1
Dembinski, A.2
Konturek, P.C.3
Ceranowicz, P.4
Konturek, S.J.5
Tomaszewska, R.6
Schuppan, D.7
Stachura, J.8
Nakamura, T.9
-
38
-
-
0036135383
-
Both thermal and non-thermal stress protect against caerulein induced pancreatitis and prevent trypsinogen activation in the pancreas
-
Frossard JL, Bhagat L, Lee HS, Hietaranta AJ, Singh VS, Song AM, Steer ML, Saluja AK. Both thermal and non-thermal stress protect against caerulein induced pancreatitis and prevent trypsinogen activation in the pancreas. Gut 2002; 50: 78-83
-
(2002)
Gut
, vol.50
, pp. 78-83
-
-
Frossard, J.L.1
Bhagat, L.2
Lee, H.S.3
Hietaranta, A.J.4
Singh, V.S.5
Song, A.M.6
Steer, M.L.7
Saluja, A.K.8
-
39
-
-
0036135867
-
The effects of hypo- and hyperthermic pretreatment on sodium taurocholate-induced acute pancreatitis in rats
-
Rakonczay Z Jr, Takacs T, Ivanyi B, Mandi Y, Papai G, Boros I, Varga IS, Jost K, Lonovics J. The effects of hypo- and hyperthermic pretreatment on sodium taurocholate-induced acute pancreatitis in rats. Pancreas 2002; 24: 83-89
-
(2002)
Pancreas
, vol.24
, pp. 83-89
-
-
Rakonczay Jr., Z.1
Takacs, T.2
Ivanyi, B.3
Mandi, Y.4
Papai, G.5
Boros, I.6
Varga, I.S.7
Jost, K.8
Lonovics, J.9
-
40
-
-
1642471825
-
Heat-shock proteins as regulators of apoptosis
-
Takayama S, Reed JC, Homma S. Heat-shock proteins as regulators of apoptosis. Oncogene 2003; 22: 9041-9047
-
(2003)
Oncogene
, vol.22
, pp. 9041-9047
-
-
Takayama, S.1
Reed, J.C.2
Homma, S.3
-
41
-
-
0028939598
-
Supramaximal secretagogue stimulation enhances heat shock protein expression in the rat pancreas
-
Weber CK, Gress T, Muller-Pillasch F, Lerch MM, Weidenbach H, Adler G. Supramaximal secretagogue stimulation enhances heat shock protein expression in the rat pancreas. Pancreas 1995; 10: 360-367
-
(1995)
Pancreas
, vol.10
, pp. 360-367
-
-
Weber, C.K.1
Gress, T.2
Muller-Pillasch, F.3
Lerch, M.M.4
Weidenbach, H.5
Adler, G.6
|