Hepatocyte growth factor increases in injured organs and functions as an organotrophic factor in rats with experimental acute pancreatitis

Pancreas

Volumn 20, Issue 1, 2000, Pages 84-93

  Ueda, Takashi ^a   Takeyama, Yoshifumi ^a   Hori, Yuichi ^a   Shinkai, Masayuki ^a   Takase, Kozo ^a   Goshima, Masahiro ^a   Yamamoto, Masahiro ^a   Kuroda, Yoshikazu ^a  

^a KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Acute pancreatitis; Apoptosis; Ascitic fluid; Cytokine; Hepatocyte growth factor; Organ failure

Indexed keywords

CERULETIDE; COMPLEMENTARY DNA; DEOXYCHOLATE SODIUM; MESSENGER RNA; NEUTRALIZING ANTIBODY; RECOMBINANT SCATTER FACTOR; SCATTER FACTOR;

ACUTE PANCREATITIS; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASCITES FLUID; CONTROLLED STUDY; DISEASE SEVERITY; EXPERIMENTAL MODEL; MALE; NONHUMAN; PANCREATITIS; PRIORITY JOURNAL; RAT;

ACUTE DISEASE; ANIMALS; APOPTOSIS; CAERULEIN; CASPASE 3; CASPASES; CELL LINE; DEOXYCHOLIC ACID; DNA FRAGMENTATION; DOGS; EDEMA; HEPATOCYTE GROWTH FACTOR; KIDNEY; LIVER; LUNG; MALE; MULTIPLE ORGAN FAILURE; PANCREATITIS; PANCREATITIS, ACUTE NECROTIZING; RATS; RATS, WISTAR; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPLEEN;

EID: 0033970607     PISSN: 08853177     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006676-200001000-00012     Document Type: Article

References (43)

1. Saitoh Y, Yamamoto M. Evaluation of severity of acute pancreatitis: according to a report of the cooperative national survey in Japan. Int J Pancreatol 1991;9:51-8.
2. Saitoh Y, Yamamoto M. Severe acute pancreatitis in Japan. In: Bradley EL III, ed. Acute pancreatitis: diagnosis and therapy. New York: Raven Press, 1994:139-44.
3. Gross V, Schölmerich J, Leser HG, et al. Granulocyte elastase in assessment of severity of acute pancreatitis: comparison with acute-phase proteins C-reactive protein, alpha 1-antitrypsin, and protease inhibitor alpha 2-macroglobulin. Dig Dis Sci 1990;35:97-105.
4. Exley AR, Leese T, Holliday MP, Swann RA, Cohen J. Endotoxaemia and serum tumour necrosis factor as prognostic markers in severe acute pancreatitis. Gut 1992;33:1126-8.
5. Leser HG, Gross V, Scheibenbogen C, et al. Elevation of serum interleukin-6 concentration precedes acute-phase response and reflects severity in acute pancreatitis. Gastroenterology 1991;101: 782-5.
6. Gross V, Andreesen R, Leser HG, et al. Interleukin-8 and neutrophil activation in acute pancreatitis. Eur J Clin Invest 1992;22: 200-3.
7. Frey CF, Wong HN, Hickman D, Pullos T. Toxicity of hemorrhagic ascitic fluid associated with hemorrhagic pancreatitis. Arch Surg 1982;117:401-4.
8. Satake K, Kanazawa G, Hiura A, et al. Renal function in experimentally induced acute pancreatitis in dogs: how it is affected by the nephrotoxic substance in pancreatic exudate from ascitic fluid. Jpn J Surg 1991;21:88-95.
9. Nishikawa J, Takeyama Y, Ueda T, et al. Induction of apoptotic cell death by pancreatitis-associated ascitic fluid in Madin-Darby canine kidney cells. FEBS Lett 1995;373:19-22.
10. Denham W, Yang J, Norman J. Evidence for an unknown component of pancreatic ascites that induces adult respiratory distress syndrome through an interleukin-1 and tumor necrosis factor-dependent mechanism. Surgery 1997;122:295-301.
11. Nakamura T, Nawa K, Ichihara A, Kaise N, Nishino T. Purification and subunit structure of hepatocyte growth factor from rat platelets. FEBS Lett 1987;224:311-6.
12. Nakamura T, Nishizawa T, Hagiya M, et al. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989;342: 440-3.
13. Gohda E, Tsubouchi H, Nakayama H, et al. Purification and partial characterization of hepatocyte growth factor from plasma of a patient with fulminant hepatic failure. J Clin Invest 1988;81: 414-9.
14. Miyazawa K, Tsubouchi H, Naka D, et al. Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor. Biochem Biophys Res Commun 1989;163:967-73.
15. Ueda T, Takeyama Y, Toyokawa A, et al. Significant elevation of serum human hepatocyte growth factor levels in patients with acute pancreatitis. Pancreas 1996;12:76-83.
16. Ueda T, Takeyama Y, Hori Y, et al. Hepatocyte growth factor in assessment of acute pancreatitis: comparison with C-reactive protein and interleukin-6. J Gastroenterol 1997;32:63-70.
17. Ueda T, Takeyama Y, Kaneda K, et al. Protective effect of a microtubule stabilizer taxol on caerulein-induced acute pancreatitis in rat. J Clin Invest 1992;89:234-43.
18. Yamada A, Matsumoto K, Iwanari H, et al. Rapid and sensitive enzyme-linked immunosorbent assay for measurement of HGF in rat and human tissues. Biomed Res 1995;16:105-14.
19. Chomczynski P. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Biol Tech 1993;15:532-5.
20. Fukamachi H, Ichinose M, Tsukada S, et al. Hepatocyte growth factor region specifically stimulates gastro-intestinal epithelial growth in primary culture. Biochem Biophys Res Commun 1994; 205:1445-51.
21. Takase K, Takeyama Y, Nishikawa J, et al. Apoptotic cell death of renal tubules in experimental severe acute pancreatiis. Surgery 1999; 125:411-20.
22. Fernandes-Alnemri T, Litwack G, Alnemri ES. CPP32: a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. J Biol Chem 1994;269:30761-4.
23. Nicholson DW, Ali A, Thornberry NA, et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 1995;376:37-43.
24. Faleiro L, Kobayashi R, Fearnhead H, Lazebnik Y. Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells. EMBO J 1997;16:2271-81.
25. Tsubouchi H, Niitani Y, Hirono S, et al. Levels of the human hepatocyte growth factor in serum of patients with various liver diseases determined by an enzyme-linked immunosorbent assay. Hepatology 1991;13:1-5.
26. Chang H, Nagao T, Ichikawa N, et al. Blood hepatocyte growth factor levels in chronic renal failure patients [Letter]. Nephron 1994;67:497-8.
27. Yanagita K, Matsumoto K, Sekiguchi K, et al. Hepatocyte growth factor may act as a pulmotrophic factor on lung regeneration after acute lung injury. J Biol Chem 1993;268:21212-7.
28. Kinoshita T, Tashiro K, Nakamura Y. Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins. Biochem Biophys Res Commun 1989;165:1229-34.
29. Nagaike M, Hirao S, Tajima H, et al. Renotropic functions of hepatocyte growth factor in renal regeneration after unilateral nephrectomy. J Biol Chem 1991;266:22781-4.
30. Yanagita K, Nagaike M, Ishibashi H, et al. Lung may have an endocrine function producing hepatocyte growth factor in response to injury of distal organs. Biochem Biophys Res Commun 1992; 182:802-9.
31. Noji S, Tashiro K, Koyama E, et al. Expression of hepatocyte growth factor gene in endothelial and Kupffer cells of damaged rat livers, as revealed by in situ hybridization. Biochem Biophys Res Commun 1990;173:42-7.
32. Igawa T, Matsumoto K, Kanda S, Saito Y, Nakamura T. Hepatocyte growth factor may function as a renotropic factor for regeneration in rats with acute renal injury. Am J Physiol 1993;265: F61-9.
33. Ishiki Y, Ohnishi H, Muto Y, Matsumoto K, Nakamura T. Direct evidence that hepatocyte growth factor is a hepatotrophic factor for liver regeneration and has a potent antihepatitis effect in vivo. Hepatology 1992;16:1227-35.
34. Miyazawa K, Shimomura T, Kitamura A, et al. Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor: structural similarity of the protease precursor to blood coagulation factor XII. J Biol Chem 1993;268:10024-8.
35. Mizuno K, Tanoue Y, Okano I, et al. Purification and characterization of hepatocyte growth factor (HGF)-converting enzyme: activation of pro-HGF. Biochem Biophys Res Commun 1994;198: 1161-9.
36. Miyazawa K, Shimomura T, Naka D, Kitamura N. Proteolytic activation of hepatocyte growth factor in response to tissue injury. J Biol Chem 1994;269:8966-70.
37. Okajima A, Miyazawa K, Naitoh Y, Inoue K, Kitamura N. Induction of hepatocyte growth factor activator messenger RNA in the liver following tissue injury and acute inflammation. Hepatology 1997;25:97-102.
38. Morita M, Watanabe Y, Akaike T. Protective effect of hepatocyte growth factor on interferon-gamma-induced cytotoxicity in mouse hepatocytes. Hepatology 1995;21:1585-93.
39. Bardelli A, Longati P, Albero D, et al. HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death. EMBO J 1996;15:6205-12.
40. Amicone L, Spagnoli FM, Spath G, et al. Transgenic expression in the liver of truncated Met blocks apoptosis and permits immortalization of hepatocytes. EMBO J 1997;16:495-503.
41. Kosai K, Matsumoto K, Nagata S, Tsujimoto Y, Nakamura T. Abrogation of Fas-induced fulminant hepatic failure in mice by hepatocyte growth factor. Biochem Biophys Res Commun 1998; 244:683-90.
42. Buttyan R, Gobe G. Apoptosis in the mammalian kidney: incidence, effectors, and molecular control in normal development and disease states. Adv Pharmacol 1997;41:369-81.
43. Liu Y, Sun AM, Dworkin LD. Hepatocyte growth factor protects renal epithelial cells from apoptotic cell death. Biochem Biophys Res Commun 1998;246:821-6.