메뉴 건너뛰기




Volumn 86, Issue 6, 2005, Pages 397-413

Neoplastic transformation and angiogenesis in the thymus of transgenic mice expressing SV40 T and t antigen under an L-pyruvate kinase promoter (SV12 mice)

Author keywords

Carcinoma; Electron microscopy; Immunochemistry; Neovascularization; Precursor of thymic epithelial cells; Thymic epithelial tumour; Transgenic mice

Indexed keywords

ANGIOGENIC FACTOR; CYTOKERATIN; CYTOKERATIN ANTIBODY; PYRUVATE KINASE; VASCULOTROPIN RECEPTOR 2;

EID: 28544449967     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.0959-9673.2005.00451.x     Document Type: Article
Times cited : (6)

References (97)
  • 1
    • 0026327553 scopus 로고
    • Transgenic models of tumor development
    • Adams J.M. & Cory S. (1991) Transgenic models of tumor development. Science 254, 1161-1167.
    • (1991) Science , vol.254 , pp. 1161-1167
    • Adams, J.M.1    Cory, S.2
  • 3
    • 0027104066 scopus 로고
    • Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages and tumors
    • Berse B., Brown L.F., Van de Water L., Dvorak H.F., Senger D.R. (1992) Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages and tumors. Mol. Biol. Cell 3, 211-220.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 211-220
    • Berse, B.1    Brown, L.F.2    Van De Water, L.3    Dvorak, H.F.4    Senger, D.R.5
  • 4
    • 0025797414 scopus 로고
    • Novel growth regulatory factors and tumor angiogenesis
    • Bicknell R. & Harris A.L. (1991) Novel growth regulatory factors and tumor angiogenesis. Eur. J. Cancer 27, 781-785.
    • (1991) Eur. J. Cancer , vol.27 , pp. 781-785
    • Bicknell, R.1    Harris, A.L.2
  • 5
    • 0029999218 scopus 로고    scopus 로고
    • The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors
    • Blackburn C.C., Augustine C.L., Li R. et al. (1996) The nu gene acts cell-autonomously and is required for differentiation of thymic epithelial progenitors. Proc. Natl. Acad. Sci. USA 93, 5742-5746.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5742-5746
    • Blackburn, C.C.1    Augustine, C.L.2    Li, R.3
  • 6
    • 0023404246 scopus 로고
    • Unexpected thymic hyperplasia in transgenic mice harboring a neuronal promoter fused with simian virus 40 large T antigen
    • Botteri F.M., Van der Putten H., Wong D.F., Sauvage C.A., Evans R.M. (1987) Unexpected thymic hyperplasia in transgenic mice harboring a neuronal promoter fused with simian virus 40 large T antigen. Mol. Cell Biol. 7, 3178-3184.
    • (1987) Mol. Cell Biol. , vol.7 , pp. 3178-3184
    • Botteri, F.M.1    Van Der Putten, H.2    Wong, D.F.3    Sauvage, C.A.4    Evans, R.M.5
  • 7
    • 0027032148 scopus 로고
    • Angiogenesis: A mechanism by which oncogenes and tumor supressor genes regulate tumorigenesis
    • Bouck N. (1992) Angiogenesis: a mechanism by which oncogenes and tumor supressor genes regulate tumorigenesis. Cancer Treat. Res. 63, 359-371.
    • (1992) Cancer Treat. Res. , vol.63 , pp. 359-371
    • Bouck, N.1
  • 9
    • 0026593331 scopus 로고
    • Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation
    • Breier G., Albrecht U., Sterrer S, Risau W. (1992) Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development 114, 521-532.
    • (1992) Development , vol.114 , pp. 521-532
    • Breier, G.1    Albrecht, U.2    Sterrer, S.3    Risau, W.4
  • 10
    • 0025200097 scopus 로고
    • Phenotypic characterization of murine thymic micro-environment
    • Brekelmans P. & Van Ewijk W. (1990) Phenotypic characterization of murine thymic micro-environment. Semin Immunol. 2, 13-24.
    • (1990) Semin Immunol. , vol.2 , pp. 13-24
    • Brekelmans, P.1    Van Ewijk, W.2
  • 11
    • 0021183267 scopus 로고
    • Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors
    • Brinster R.L., Chen H.Y., Messing A., Van Dyke T., Levine A.J., Palmiter R.D. (1984) Transgenic mice harboring SV40 T-antigen genes develop characteristic brain tumors. Cell 37, 367-379.
    • (1984) Cell , vol.37 , pp. 367-379
    • Brinster, R.L.1    Chen, H.Y.2    Messing, A.3    Van Dyke, T.4    Levine, A.J.5    Palmiter, R.D.6
  • 12
    • 0036948242 scopus 로고    scopus 로고
    • Intussuceptive angiogenesis, the alternative to capillary sprouting
    • Burri P. & Djonov V. (2002) Intussuceptive angiogenesis, the alternative to capillary sprouting. Mol. Aspects Med. 23, S1-S27.
    • (2002) Mol. Aspects Med. , vol.23
    • Burri, P.1    Djonov, V.2
  • 13
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P. (2000) Mechanisms of angiogenesis and arteriogenesis. Nat. Med. 6, 389-395.
    • (2000) Nat. Med. , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 15
    • 0024461206 scopus 로고
    • Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis
    • Connolly D.T., Heuvelman D.M., Nelson R. et al. (1989) Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J. Clin. Invest. 84, 1470-1478.
    • (1989) J. Clin. Invest. , vol.84 , pp. 1470-1478
    • Connolly, D.T.1    Heuvelman, D.M.2    Nelson, R.3
  • 16
    • 0022033592 scopus 로고
    • Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: Strategies, applications and limitations
    • Cooper D., Schermer A., Sun T.T. (1985) Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: strategies, applications and limitations. Lab. Invest. 52, 243-256.
    • (1985) Lab. Invest. , vol.52 , pp. 243-256
    • Cooper, D.1    Schermer, A.2    Sun, T.T.3
  • 18
    • 0021327652 scopus 로고
    • Immunohistochemical distinction of human carcinomas by cytokeratin typing with monoclonal antibodies
    • Debus E., Moll R., Francke W.W., Weber K., Osborn M. (1984) Immunohistochemical distinction of human carcinomas by cytokeratin typing with monoclonal antibodies. Am. J. Pathol. 114, 121-130.
    • (1984) Am. J. Pathol. , vol.114 , pp. 121-130
    • Debus, E.1    Moll, R.2    Francke, W.W.3    Weber, K.4    Osborn, M.5
  • 19
    • 0029004025 scopus 로고
    • Vascular permeability factor/vascular endothelial growth factor, microvascular, hyperpermeability and angiogenesis
    • Dvorak H.F., Brown L.F., Detmar M., Dvorak A.M. (1995) Vascular permeability factor/vascular endothelial growth factor, microvascular, hyperpermeability and angiogenesis. Am. J. Pathol. 146, 1029-1039.
    • (1995) Am. J. Pathol. , vol.146 , pp. 1029-1039
    • Dvorak, H.F.1    Brown, L.F.2    Detmar, M.3    Dvorak, A.M.4
  • 20
    • 0023412375 scopus 로고
    • Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes
    • Efrat S., Baekkeskov S., Lane D., Hanahan D. (1987) Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes. EMBO J. 6, 2699-2704.
    • (1987) EMBO J. , vol.6 , pp. 2699-2704
    • Efrat, S.1    Baekkeskov, S.2    Lane, D.3    Hanahan, D.4
  • 21
    • 0019904453 scopus 로고
    • Immunohistochemical localization of keratin-type proteins in epithelial neoplasms
    • Espinoza G.G. & Azar H.A. (1982) Immunohistochemical localization of keratin-type proteins in epithelial neoplasms. Am. J. Clin. Pathol. 78, 500-507.
    • (1982) Am. J. Clin. Pathol. , vol.78 , pp. 500-507
    • Espinoza, G.G.1    Azar, H.A.2
  • 22
    • 0029127218 scopus 로고
    • The role of vascular endothelial growth factor in pathological angiogenesis
    • Ferrara N. (1995) The role of vascular endothelial growth factor in pathological angiogenesis. Breast Cancer Res. Treat. 36, 127-137.
    • (1995) Breast Cancer Res. Treat. , vol.36 , pp. 127-137
    • Ferrara, N.1
  • 23
    • 0025329430 scopus 로고
    • Expression of the CD34 gene in vascular endothelial cells
    • Fina L., Molgaard H.V., Robertson D. et al. (1990) Expression of the CD34 gene in vascular endothelial cells. Blood 75, 2417-2426.
    • (1990) Blood , vol.75 , pp. 2417-2426
    • Fina, L.1    Molgaard, H.V.2    Robertson, D.3
  • 24
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other diseases
    • Folkman J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other diseases. Nat. Med. 1, 27-31.
    • (1995) Nat. Med. , vol.1 , pp. 27-31
    • Folkman, J.1
  • 25
    • 0023157363 scopus 로고
    • Angiogenic factors
    • Folkman J. & Klagsbrun M. (1987) Angiogenic factors. Science 235, 442-447.
    • (1987) Science , vol.235 , pp. 442-447
    • Folkman, J.1    Klagsbrun, M.2
  • 26
    • 0024549349 scopus 로고
    • Induction of angiogenesis during the transition from hyperplasia to neoplasia
    • Folkman J., Watson K., Ingber D., Hanahan D. (1989) Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 359, 58-61.
    • (1989) Nature , vol.359 , pp. 58-61
    • Folkman, J.1    Watson, K.2    Ingber, D.3    Hanahan, D.4
  • 27
    • 0022859788 scopus 로고
    • Endothelial cell proliferation during angiogenesis. In vitro modulation of basement membrane components
    • Form D.M., Pratt B.M., Madri J.A. (1986) Endothelial cell proliferation during angiogenesis. In vitro modulation of basement membrane components. Lab. Invest. 55, 521-530.
    • (1986) Lab. Invest. , vol.55 , pp. 521-530
    • Form, D.M.1    Pratt, B.M.2    Madri, J.A.3
  • 28
    • 0019888709 scopus 로고
    • Diversity of cytokeratins: Differentiation specific expression of cytokeratin polypeptides in epithelial cells and tissues
    • Franke W.W., Schiller D.L., Moll R. et al. (1981) Diversity of cytokeratins: differentiation specific expression of cytokeratin polypeptides in epithelial cells and tissues. J. Mol. Biol. 153, 933-959.
    • (1981) J. Mol. Biol. , vol.153 , pp. 933-959
    • Franke, W.W.1    Schiller, D.L.2    Moll, R.3
  • 29
    • 0027185780 scopus 로고
    • The morphology, immunochemistry and incidence of hematopoietic neoplasm in mice and rats
    • Frith C.H., Ward J.M., Chandra M. (1993) The morphology, immunochemistry and incidence of hematopoietic neoplasm in mice and rats. Toxicol. Pathol. 21, 206-218.
    • (1993) Toxicol. Pathol. , vol.21 , pp. 206-218
    • Frith, C.H.1    Ward, J.M.2    Chandra, M.3
  • 31
    • 0027361967 scopus 로고
    • Untransfected and SV40-transfected fetal and post-natal human thymic stroma cells
    • Galy A.H., de Waal Malefyt R., Barcena A., Mohan-Peterson S., Spits H. (1993) Untransfected and SV40-transfected fetal and post-natal human thymic stroma cells. Thymus 22, 13-33.
    • (1993) Thymus , vol.22 , pp. 13-33
    • Galy, A.H.1    De Waal Malefyt, R.2    Barcena, A.3    Mohan-Peterson, S.4    Spits, H.5
  • 33
    • 0345535163 scopus 로고
    • Oncogenesis in transgenic mice
    • Berlin: Springer Verlag
    • Hanahan D. (1986) Oncogenesis in transgenic mice. In: Oncogenes and Growth Control, pp. 349-363. Berlin: Springer Verlag.
    • (1986) Oncogenes and Growth Control , pp. 349-363
    • Hanahan, D.1
  • 34
    • 0024155366 scopus 로고
    • Dissecting multistep tumorigenesis in transgenic mice
    • Hanahan D. (1988) Dissecting multistep tumorigenesis in transgenic mice. Annu. Rev. Genet. 22, 479-519.
    • (1988) Annu. Rev. Genet. , vol.22 , pp. 479-519
    • Hanahan, D.1
  • 35
    • 0030851764 scopus 로고    scopus 로고
    • Signaling vascular morphogenesis and maintenance
    • Hanahan D. (1997) Signaling vascular morphogenesis and maintenance. Science 277, 48-50.
    • (1997) Science , vol.277 , pp. 48-50
    • Hanahan, D.1
  • 36
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D. & Folkman J. (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86, 335-364.
    • (1996) Cell , vol.86 , pp. 335-364
    • Hanahan, D.1    Folkman, J.2
  • 38
    • 0024434311 scopus 로고
    • Primary polyoma virus-induced murine thymic epithelial tumors
    • Hoot G.P. & Kettman J.R. (1989) Primary polyoma virus-induced murine thymic epithelial tumors. Am. J. Pathol. 135, 679-695.
    • (1989) Am. J. Pathol. , vol.135 , pp. 679-695
    • Hoot, G.P.1    Kettman, J.R.2
  • 39
    • 0021719091 scopus 로고
    • Simple epithelial nature of simian virus-40-transformed human epidermal keratinocytes
    • Hornis T.S., Steinberg M.L., Defendi V., Sun T.T. (1984) Simple epithelial nature of simian virus-40-transformed human epidermal keratinocytes. Cancer Res. 44, 5797-5804.
    • (1984) Cancer Res. , vol.44 , pp. 5797-5804
    • Hornis, T.S.1    Steinberg, M.L.2    Defendi, V.3    Sun, T.T.4
  • 40
    • 0024439457 scopus 로고
    • How does extracellular matrix control capillary morphogenesis
    • Ingber D.E. & Folkman J. (1989) How does extracellular matrix control capillary morphogenesis. Cell 58, 803-805.
    • (1989) Cell , vol.58 , pp. 803-805
    • Ingber, D.E.1    Folkman, J.2
  • 41
    • 0026502754 scopus 로고
    • Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissue
    • Jakeman L.B., Winer J., Bennett G.L., Altar C.A., Ferrara N. (1992) Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissue. J. Clin. Invest. 89, 244-253.
    • (1992) J. Clin. Invest. , vol.89 , pp. 244-253
    • Jakeman, L.B.1    Winer, J.2    Bennett, G.L.3    Altar, C.A.4    Ferrara, N.5
  • 42
    • 0000116760 scopus 로고
    • New approaches to the diagnosis of thymic epithelial tumors
    • Kirchner T. & Muller-Hermelink H.K. (1989) New approaches to the diagnosis of thymic epithelial tumors. Prog. Surg. Pathol. 10, 167-189.
    • (1989) Prog. Surg. Pathol. , vol.10 , pp. 167-189
    • Kirchner, T.1    Muller-Hermelink, H.K.2
  • 44
    • 0000004505 scopus 로고
    • VEGF/VPF: The angiogenesis factor found?
    • Klagsbrun M. & Soker S. (1993) VEGF/VPF: the angiogenesis factor found? Current Biol. 10, 699-702.
    • (1993) Current Biol. , vol.10 , pp. 699-702
    • Klagsbrun, M.1    Soker, S.2
  • 46
    • 0037105620 scopus 로고    scopus 로고
    • Cutting edge: Thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus
    • Klug D.B., Carter C., Gimenez-Conti I.B., Richie E.R. (2002) Cutting edge: Thymocyte-independent and thymocyte-dependent phases of epithelial patterning in the fetal thymus. J. Immunol. 169, 2842-2845.
    • (2002) J. Immunol. , vol.169 , pp. 2842-2845
    • Klug, D.B.1    Carter, C.2    Gimenez-Conti, I.B.3    Richie, E.R.4
  • 47
    • 0004283106 scopus 로고
    • Tumors of the thymic epithelial cells
    • (ed. M. Kornstein). Philadelphia: W. Saunders
    • Kornstein M. & Deblois G. (1995) Tumors of the thymic epithelial cells. In: Pathology of the Thymus and Mediastinum, Vol. 33, pp. 67-113. (ed. M. Kornstein). Philadelphia: W. Saunders.
    • (1995) Pathology of the Thymus and Mediastinum , vol.33 , pp. 67-113
    • Kornstein, M.1    Deblois, G.2
  • 48
    • 0031795886 scopus 로고    scopus 로고
    • Thymic carcinoma arising in thymoma is associated with alterations in immunohistochemical profile
    • Kuo T.T. & Chan J.K. (1998) Thymic carcinoma arising in thymoma is associated with alterations in immunohistochemical profile. Am. J. Surg. Pathol. 22, 1474-1481.
    • (1998) Am. J. Surg. Pathol. , vol.22 , pp. 1474-1481
    • Kuo, T.T.1    Chan, J.K.2
  • 49
    • 0018348655 scopus 로고
    • T antigen is bound to a host protein in SV40-transformed cells
    • Lane D.P. & Crawford L.V. (1979) T antigen is bound to a host protein in SV40-transformed cells. Nature 278, 261-263.
    • (1979) Nature , vol.278 , pp. 261-263
    • Lane, D.P.1    Crawford, L.V.2
  • 50
    • 0025154957 scopus 로고
    • Modulation of p53 gene expression of cytokeratin 18 in retinoid-mediated invasion suppressed lung carcinoma cells
    • Ledinko N. & Costantino R.L. (1990) Modulation of p53 gene expression of cytokeratin 18 in retinoid-mediated invasion suppressed lung carcinoma cells. Anticancer Res. 10, 1335-1339.
    • (1990) Anticancer Res. , vol.10 , pp. 1335-1339
    • Ledinko, N.1    Costantino, R.L.2
  • 51
    • 0031613224 scopus 로고    scopus 로고
    • Thymic epithelial tumor progression in an SV40 T transgenic mouse model
    • Lee S.S., Park W.Y., Chi J.G. et al. (1998) Thymic epithelial tumor progression in an SV40 T transgenic mouse model. Virchows Arch. 432, 33-42.
    • (1998) Virchows Arch. , vol.432 , pp. 33-42
    • Lee, S.S.1    Park, W.Y.2    Chi, J.G.3
  • 52
    • 0024818355 scopus 로고
    • Vascular endothelial growth factor is a secreted angiogenic mitogen
    • Leung D.W., Cachianes G., Kuang W.J., Goeddel D.V., Ferrara N. (1989) Vascular endothelial growth factor is a secreted angiogenic mitogen. Science 246, 1306-1309.
    • (1989) Science , vol.246 , pp. 1306-1309
    • Leung, D.W.1    Cachianes, G.2    Kuang, W.J.3    Goeddel, D.V.4    Ferrara, N.5
  • 53
    • 0028204538 scopus 로고
    • The role of the p53 tumor-suppressor gene in tumorigenesis
    • Levine A.J., Perry M.E., Chang A. et al. (1994) The role of the p53 tumor-suppressor gene in tumorigenesis. Br. J. Cancer 69, 409-116.
    • (1994) Br. J. Cancer , vol.69 , pp. 409-1116
    • Levine, A.J.1    Perry, M.E.2    Chang, A.3
  • 54
    • 85173202830 scopus 로고
    • CD31: A new marker for vascular neoplasia
    • Longacre T. & Rouse R. (1994) CD31: a new marker for vascular neoplasia. Adv. Anat. Pathol. 1, 16-20.
    • (1994) Adv. Anat. Pathol. , vol.1 , pp. 16-20
    • Longacre, T.1    Rouse, R.2
  • 55
    • 0020358138 scopus 로고
    • Comparative investigation of keratin filaments in normal tissues and tumours of skin, oral mucosa, salivary glands and thymus
    • Loning T., Viac J., Caselitz J., Thivolet J., Otto H.F., Seifert G. (1982) Comparative investigation of keratin filaments in normal tissues and tumours of skin, oral mucosa, salivary glands and thymus. Pathol. Res. Pract. 175, 256-265.
    • (1982) Pathol. Res. Pract. , vol.175 , pp. 256-265
    • Loning, T.1    Viac, J.2    Caselitz, J.3    Thivolet, J.4    Otto, H.F.5    Seifert, G.6
  • 56
    • 0027218350 scopus 로고
    • Interaction between SV40 large-tumor antigen and the growth suppressor proteins pRb and p53
    • Ludlow J.W. (1993) Interaction between SV40 large-tumor antigen and the growth suppressor proteins pRb and p53. FASEB J. 5, 866-871.
    • (1993) FASEB J. , vol.5 , pp. 866-871
    • Ludlow, J.W.1
  • 57
    • 0016702186 scopus 로고
    • Ultrastructure of spontaneous and urethan-induced thymomas in Buffalo rats
    • Matsuyama M., Suzuki H., Yamada S., Ito M., Nagayo T. (1975) Ultrastructure of spontaneous and urethan-induced thymomas in Buffalo rats. Cancer Res. 35, 2771-2779.
    • (1975) Cancer Res. , vol.35 , pp. 2771-2779
    • Matsuyama, M.1    Suzuki, H.2    Yamada, S.3    Ito, M.4    Nagayo, T.5
  • 58
    • 0028224556 scopus 로고
    • Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53
    • McCarthy S.A., Symonds H.S., Van Dyke T. (1994) Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53. Proc. Natl. Acad. Sci. USA 91, 3979-3983.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3979-3983
    • McCarthy, S.A.1    Symonds, H.S.2    Van Dyke, T.3
  • 59
    • 0024242333 scopus 로고
    • Developmental study of SV40 large T antigen expression in transgenic mice with choroid plexus neoplasia
    • Messing A., Pinkert C.A., Palmiter R.D., Brinster R.L. (1988) Developmental study of SV40 large T antigen expression in transgenic mice with choroid plexus neoplasia. Oncogene Res. 3, 87-97.
    • (1988) Oncogene Res. , vol.3 , pp. 87-97
    • Messing, A.1    Pinkert, C.A.2    Palmiter, R.D.3    Brinster, R.L.4
  • 60
    • 0027466849 scopus 로고
    • High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis
    • Millauer B., Wizigmann-Voos S., Schnurch H. et al. (1993) High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72, 835-846.
    • (1993) Cell , vol.72 , pp. 835-846
    • Millauer, B.1    Wizigmann-Voos, S.2    Schnurch, H.3
  • 61
    • 0026439404 scopus 로고
    • Transgenes encoding mutant simian virus 40 large T antigens unmask phenotypic and functional constraints in thymic epithelial cells
    • Moll J., Eibel H., Botteri F., Sansig G., Regnier C., van der Putten H. (1992) Transgenes encoding mutant simian virus 40 large T antigens unmask phenotypic and functional constraints in thymic epithelial cells. Oncogene 7, 2175-2187.
    • (1992) Oncogene , vol.7 , pp. 2175-2187
    • Moll, J.1    Eibel, H.2    Botteri, F.3    Sansig, G.4    Regnier, C.5    Van Der Putten, H.6
  • 62
    • 0020282994 scopus 로고
    • Complex cytokeratin polypeptide patterns observed in certain human carcinomas
    • Moll R., Krepler R., Franke W.W. (1983) Complex cytokeratin polypeptide patterns observed in certain human carcinomas. Differentiation 23, 256-269.
    • (1983) Differentiation , vol.23 , pp. 256-269
    • Moll, R.1    Krepler, R.2    Franke, W.W.3
  • 63
    • 0025173179 scopus 로고
    • Sequential loss of suppressor genes for three specific functions during in vivo carcinogenesis
    • Moroco J.R., Solt D.B., Polverini P.J. (1990) Sequential loss of suppressor genes for three specific functions during in vivo carcinogenesis. Lab. Invest. 63, 298-306.
    • (1990) Lab. Invest. , vol.63 , pp. 298-306
    • Moroco, J.R.1    Solt, D.B.2    Polverini, P.J.3
  • 64
    • 0002564010 scopus 로고
    • Advances in the diagnosis and classification of thymic epithelial tumors
    • Muller-Hermelink H., Marx A., Kirchner T. (1994) Advances in the diagnosis and classification of thymic epithelial tumors. Rec. Adv. Histopathol. 16, 49-72.
    • (1994) Rec. Adv. Histopathol. , vol.16 , pp. 49-72
    • Muller-Hermelink, H.1    Marx, A.2    Kirchner, T.3
  • 65
    • 0021995838 scopus 로고
    • Incidence, morphology and ultrastructure of spontaneous thymoma, the most common neoplasm in W/Nhg rats
    • Murray A.B., Schaffer E., Nussel M., LuZ. A. (1985) Incidence, morphology and ultrastructure of spontaneous thymoma, the most common neoplasm in W/Nhg rats. J. Natl. Cancer Inst 75, 369-379.
    • (1985) J. Natl. Cancer Inst , vol.75 , pp. 369-379
    • Murray, A.B.1    Schaffer, E.2    Nussel, M.3    Luz, A.4
  • 66
    • 0023115224 scopus 로고
    • Ultrastructural studies of thymic reticulum. I. Epithelial components
    • Nabarra B. & Andrianarison I. (1987) Ultrastructural studies of thymic reticulum. I. Epithelial components. Thymus 9, 95-121.
    • (1987) Thymus , vol.9 , pp. 95-121
    • Nabarra, B.1    Andrianarison, I.2
  • 67
    • 0035148297 scopus 로고    scopus 로고
    • Ultrastructural study of the FVB/N mouse thymus: Presence of an immature epithelial cell in the medulla and premature involution
    • Nabarra B., Mulotte M., Casanova M., Godard C., London J. (2001) Ultrastructural study of the FVB/N mouse thymus: presence of an immature epithelial cell in the medulla and premature involution. Dev. Comp. Immunol. 25, 231-243.
    • (2001) Dev. Comp. Immunol. , vol.25 , pp. 231-243
    • Nabarra, B.1    Mulotte, M.2    Casanova, M.3    Godard, C.4    London, J.5
  • 68
    • 28544451760 scopus 로고    scopus 로고
    • (Erratum in Dev. Comp. Immunol. 25, 539-543).
    • Comp. Immunol. , vol.25 , pp. 539-543
  • 69
    • 0042831989 scopus 로고    scopus 로고
    • Early steps of a thymic tumor in SV40 transgenic mice: Hyperplasia of medullary epithelial cells and increased mature thymocyte number disturb thymic export
    • Nabarra B., Martinon C., Godard C. et al. (2002) Early steps of a thymic tumor in SV40 transgenic mice: hyperplasia of medullary epithelial cells and increased mature thymocyte number disturb thymic export. Dev. Immunol. 9, 223-231.
    • (2002) Dev. Immunol. , vol.9 , pp. 223-231
    • Nabarra, B.1    Martinon, C.2    Godard, C.3
  • 72
    • 0022361679 scopus 로고
    • SV40 enhancer and large T antigen are instrumental in development of choroid plexus tumors in transgenic mice
    • Palmiter R., Chen H.Y., Messing A., Brinster R.L. (1985) SV40 enhancer and large T antigen are instrumental in development of choroid plexus tumors in transgenic mice. Nature 316, 457-460.
    • (1985) Nature , vol.316 , pp. 457-460
    • Palmiter, R.1    Chen, H.Y.2    Messing, A.3    Brinster, R.L.4
  • 73
    • 0030598152 scopus 로고    scopus 로고
    • Development of thymic carcinoma in transgenic mice expressing SV40 T antigen
    • Park W.Y., Kim J.I., Shim E.H. et al. (1996) Development of thymic carcinoma in transgenic mice expressing SV40 T antigen. Cancer Lett. 107, 293-300.
    • (1996) Cancer Lett. , vol.107 , pp. 293-300
    • Park, W.Y.1    Kim, J.I.2    Shim, E.H.3
  • 74
    • 0026446102 scopus 로고
    • Vascular endothelial growth is a potential tumor angiogenesis factor in vivo
    • Plate K.H., Breir G., Weich H.A., Risau W. (1992) Vascular endothelial growth is a potential tumor angiogenesis factor in vivo. Nature 359, 845-848.
    • (1992) Nature , vol.359 , pp. 845-848
    • Plate, K.H.1    Breir, G.2    Weich, H.A.3    Risau, W.4
  • 75
    • 0027249239 scopus 로고
    • Fetal liver kinase-1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium
    • Quinn T.P., Peters K.G., De Vries C., Ferrara N., Williams L.T. (1993) Fetal liver kinase-1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium. Proc. Natl. Acad. Sci. USA 90, 7533-7537.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7533-7537
    • Quinn, T.P.1    Peters, K.G.2    De Vries, C.3    Ferrara, N.4    Williams, L.T.5
  • 77
    • 0021992198 scopus 로고
    • Cytokeratin expression during neoplastic progression of human transitional cell carcinomas as detetected by monoclonal and polyclonal antibodies
    • Ramaekers F., Huysmans A., Moesker O., Schaart O., Herman C., Vooijs P. (1985) Cytokeratin expression during neoplastic progression of human transitional cell carcinomas as detetected by monoclonal and polyclonal antibodies. Lab. Invest. 52, 31-38.
    • (1985) Lab. Invest. , vol.52 , pp. 31-38
    • Ramaekers, F.1    Huysmans, A.2    Moesker, O.3    Schaart, O.4    Herman, C.5    Vooijs, P.6
  • 79
    • 0002808372 scopus 로고
    • Vasculogenesis, angiogenesis and endothelial cell differentiation during embryonic development
    • (eds. R. Feinberg, G. Sherer, R. Auerbach). Basel: Karger
    • Risau W. (1991) Vasculogenesis, angiogenesis and endothelial cell differentiation during embryonic development. In: The Development of Vascular System, pp. 58-68. (eds. R. Feinberg, G. Sherer, R. Auerbach). Basel: Karger.
    • (1991) The Development of Vascular System , pp. 58-68
    • Risau, W.1
  • 80
    • 0002385062 scopus 로고
    • Tumors of the thymus
    • Washington, DC: Armed Forces Institute of Pathology
    • Rosai J. & Levine G. (1976) Tumors of the thymus. In: Atlas of Tumor Pathology, Vol. 13. Washington, DC: Armed Forces Institute of Pathology.
    • (1976) Atlas of Tumor Pathology , vol.13
    • Rosai, J.1    Levine, G.2
  • 81
    • 0028226679 scopus 로고
    • Induction versus progression of brain tumor development: Differential functions for pRb- and p53-targeting domains of simian virus 40 T antigen
    • Saenz-Robles M.T., Symonds H., Chen J., Van Dyke T. (1994) Induction versus progression of brain tumor development: differential functions for pRb- and p53-targeting domains of simian virus 40 T antigen. Mol. Cell Biol. 14, 2686-2698.
    • (1994) Mol. Cell Biol. , vol.14 , pp. 2686-2698
    • Saenz-Robles, M.T.1    Symonds, H.2    Chen, J.3    Van Dyke, T.4
  • 82
    • 0023741229 scopus 로고
    • Immunohistochemical studies on a human thymic epithelial cell subset defined by the anticytokeratin 18 monoclonal antibody
    • Savino W. & Dardenne M. (1988) Immunohistochemical studies on a human thymic epithelial cell subset defined by the anticytokeratin 18 monoclonal antibody. Cell Tissue Res. 254, 225-231.
    • (1988) Cell Tissue Res. , vol.254 , pp. 225-231
    • Savino, W.1    Dardenne, M.2
  • 83
    • 0025376269 scopus 로고
    • Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma
    • Schlingemann R.O., Rietveld F.J., de Waal R.M. et al. (1990) Leukocyte antigen CD34 is expressed by a subset of cultured endothelial cells and on endothelial abluminal microprocesses in the tumor stroma. Lab. Invest. 62, 690-696.
    • (1990) Lab. Invest. , vol.62 , pp. 690-696
    • Schlingemann, R.O.1    Rietveld, F.J.2    De Waal, R.M.3
  • 84
    • 0021025634 scopus 로고
    • Tumor angiogenesis
    • Schor A.M. & Schor S.L. (1983) Tumor angiogenesis. J. Pathol. 141, 385-413.
    • (1983) J. Pathol. , vol.141 , pp. 385-413
    • Schor, A.M.1    Schor, S.L.2
  • 86
    • 0024432857 scopus 로고
    • Development of a transgenic mouse system for the analysis of stages in liver carcinoma genesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene
    • Sepulveda A.R., Finegold M.J., Smith B. et al. (1989) Development of a transgenic mouse system for the analysis of stages in liver carcinoma genesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene. Cancer Res. 49, 6108-6117.
    • (1989) Cancer Res. , vol.49 , pp. 6108-6117
    • Sepulveda, A.R.1    Finegold, M.J.2    Smith, B.3
  • 87
    • 0030831104 scopus 로고    scopus 로고
    • A requirement for Flk-1 in primitive and definitive hematopoiesis and vasculogenesis
    • Shalaby F., Ho J., Standford W.L. et al. (1997) A requirement for Flk-1 in primitive and definitive hematopoiesis and vasculogenesis. Cell 89, 981-990.
    • (1997) Cell , vol.89 , pp. 981-990
    • Shalaby, F.1    Ho, J.2    Standford, W.L.3
  • 88
  • 89
    • 0031923926 scopus 로고    scopus 로고
    • Thymic carcinoma: Spectrum of differentiation and histologic types
    • Suster S. & Moran C.A. (1998) Thymic carcinoma: spectrum of differentiation and histologic types. Pathology 30, 111-122.
    • (1998) Pathology , vol.30 , pp. 111-122
    • Suster, S.1    Moran, C.A.2
  • 90
    • 0032930437 scopus 로고    scopus 로고
    • Primary thymic epithelial neoplasms: Spectrum of differentiation and histological features
    • Suster S. & Moran C.A. (1999) Primary thymic epithelial neoplasms: spectrum of differentiation and histological features. Semin. Diagn. Pathol. 16, 2-17.
    • (1999) Semin. Diagn. Pathol. , vol.16 , pp. 2-17
    • Suster, S.1    Moran, C.A.2
  • 92
    • 0028827184 scopus 로고
    • Thymic epithelial neoplasm in transgenic mice expressing SV40 T antigen under the control of an erythroid-specific enhancer
    • Teitz. T., Chang J.C., Kan Y.W., Yen T.S. (1995) Thymic epithelial neoplasm in transgenic mice expressing SV40 T antigen under the control of an erythroid-specific enhancer. J. Pathol. 177, 309-315.
    • (1995) J. Pathol. , vol.177 , pp. 309-315
    • Teitz, T.1    Chang, J.C.2    Kan, Y.W.3    Yen, T.S.4
  • 93
    • 0021351439 scopus 로고
    • Profiles of keratin proteins in basal and squamous cell carcinomas in the skin. An immunohistochemical study
    • Thomas P., Said J.W., Nash G., Banks-Schlegel S. (1984) Profiles of keratin proteins in basal and squamous cell carcinomas in the skin. An immunohistochemical study. Lab. Invest. 50, 36-41.
    • (1984) Lab. Invest. , vol.50 , pp. 36-41
    • Thomas, P.1    Said, J.W.2    Nash, G.3    Banks-Schlegel, S.4
  • 95
    • 0020187802 scopus 로고
    • Correlation of specific keratins with different types of epithelial differentiation: Monoclonal antibody studies
    • Tseng S.C., Jarvinen M.J., Nelson W.G., Huang J.W., Woodcock-Mitchell J., Sun T.T. (1982) Correlation of specific keratins with different types of epithelial differentiation: monoclonal antibody studies. Cell 30, 361-372.
    • (1982) Cell , vol.30 , pp. 361-372
    • Tseng, S.C.1    Jarvinen, M.J.2    Nelson, W.G.3    Huang, J.W.4    Woodcock-Mitchell, J.5    Sun, T.T.6
  • 96
    • 0023265556 scopus 로고
    • Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice
    • Van Dyke T.A., Finlay C., Miller D., Marks J., Lozano G., Levine A.J. (1987) Relationship between simian virus 40 large tumor antigen expression and tumor formation in transgenic mice. J. Virol. 61, 2029-2032.
    • (1987) J. Virol. , vol.61 , pp. 2029-2032
    • Van Dyke, T.A.1    Finlay, C.2    Miller, D.3    Marks, J.4    Lozano, G.5    Levine, A.J.6
  • 97
    • 0025645648 scopus 로고
    • Applications of immunohistochemistry in rodent tumor pathology
    • Ward J.M. & Rehm S. (1990) Applications of immunohistochemistry in rodent tumor pathology. Exp. Pathol. 40, 301-312.
    • (1990) Exp. Pathol. , vol.40 , pp. 301-312
    • Ward, J.M.1    Rehm, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.