Thymic epithelial tumour progression in an SV40T transgenic mouse model

Virchows Archiv

Volumn 432, Issue 1, 1998, Pages 33-42

  Lee, Seung Sook ^b   Park, Woong Yang ^c   Chi, Je Geun ^a   Seo, Jeong Wook ^a   Kim, Jong Il ^c   Kim, Chul Woo ^a   Park, Sung Hoe ^a   Khang, Shin Kwang ^b   Cho, Kyung Ja ^b   Seo, Jeong Sun ^c   Jang, Ja June ^a  

^a Seoul National University   (South Korea)

^b Korea Cancer Centre Hospital   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

SV40T; Thymic carcinoma; Thymoma; Thymus; Transgenic mouse

Indexed keywords

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER MODEL; CARCINOMA; CONTROLLED STUDY; EPITHELIUM TUMOR; MOUSE; NONHUMAN; ORGAN SIZE; PRIORITY JOURNAL; SIMIAN VIRUS 40; THYMOMA; TRANSGENIC MOUSE; TUMOR DIFFERENTIATION; TUMOR GROWTH; ANIMAL; C57BL MOUSE; CBA MOUSE; CELL DIFFERENTIATION; DISEASE COURSE; DISEASE MODEL; ENZYME IMMUNOASSAY; FEMALE; GENETICS; MALE; METABOLISM; PATHOLOGY;

VIRUS T ANTIGEN;

AGING; ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CARCINOMA; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; IMMUNOENZYME TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, TRANSGENIC; THYMOMA; THYMUS NEOPLASMS;

EID: 0031613224     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004280050131     Document Type: Article

References (61)

1. Behringer RR, Peschon JJ, Messing A, Gartside CL, Hauschka SD, Palmiter RD, Brinster RL (1988) Heart and bone tumours in transgenic mice. Proc Natl Acad Sci USA 85:2648-2652
2. Boeckman DE, Stutman O (1969) Fine structure of a transplanted chemically induced non-lymphoid thymoma. Cancer Res 29:1663-1668
3. Botteri FM, van der Putten H, Wong DF, Sauvage CA, Evans RM (1987) Unexpected thymic hyperplasia in transgenic mice harboring a neuronal promoter fused with Simian Virus 40 large T antigen. Mol Cell Biol 7:3178-3184
4. Bradl M, Klein Szanto A, Porter S, Mintz B (1991) Malignant melanoma in transgenic mice. Proc Natl Acad Sci USA 88:164-168
5. Brinster RL, Chen HY, Messing A, Dyke T van, Levine AJ, Palmiter RD (1984) Transgenic mice harboring SV40T-antigen genes develop characteristic brain tumours. Cell 37:367-379
6. Ceci JD, Kovatch RM, Wing DA, Jones JM, Snow CM, Rosenberg MP, Jenkins NA, Copeland NG, Meisler MH (1991) Transgenic mice carrying a murine amylase 2.2/SV40 T antigen fusion gene develop pancreatic acinar cell and stomach carcinoma. Oncogene 6:323-332
7. Chen J, Dyke T van (1991) Uniform cell-autonomous tumourigenesis of the choroid plexus by Papovavirus large T antigens. Mol Cell Biol 11:5968-5976
8. Cory S, Adams J (1988) Transgenic mice and ontogenesis. Annu Rev Immmunol 6:25-48
9. Cuthbertson RA, Klintworth GK (1988) Transgenic mice: a gold mine for furthering knowledge in pathobiology. Lab Invest 58:484-502
10. Efrat S, Baekkeskov S, Lane D, Hanahan D (1987) Coordinate expression of the endo-geneous p53 gene in cells of transgenic mice expressing hybrid insulin-SV40T antigen genes. EMBO J 6:2699-2704
11. Fox N, Crooke R, Hwang LH, Schibler U, Knowles BB, Solter D (1989) Metastatic hibernomas in transgenic mice expressing an alpha-amylase-SV40 T antigen hybrid gene. Science 244: 461-463
12. Hanahan D (1985) Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes. Nature 315:115-122
13. Hartman C-A, Roth C, Minck C, Niedobitek G (1990) Thymic carcinoma: report of five cases and review of literature. Cancer Res Clin Oncol 116:69-82
14. Herczeg E, Kahn LB (1986) Primary thymic carcinomas: an unusual case originating in a lymphocyte-rich thymoma. Virchows Arch [A] 409:163-169
15. Hirokawa K, Utsuyama M, Moriizumi E, Handa S (1986) Analysis of the thymic micro-environment by monoclonal antibodies with special reference to thymic nurse cells. Thymus 8:349-360
16. Hogan BLM, Constantini F, Lacy E (1991) Manipulating the mouse embryo: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor
17. Hoot GP, Kettman JR (1989) Primary polyoma virus-induced murine thymic epithelial tumours: a tumour model of thymus physiology. Am J Pathol 135: 679-695
18. Kirchner T, Muller-Hermelink HK (1989) New approaches to the diagnosis of thymic epithelial tumours. Prog Surg Pathol 10:167-189
19. Kirchner T, Schalke B, Buchwald J, Ritter M, Marx A, Muller-Hermelink HK (1992) Well-differentiated thymic carcinoma. An organotypical low-grade carcinoma with relationship to cortical thymoma. Am J Surg Pathol 16:1153-1169
20. Knowles BB, McCarrick J, Fox N, Solter D, Damjanov I (1990) Osteosarcomas in transgenic mice expressing an alpha-amylase-SV40 T-antigen hybrid gene. Am J Pathol 137:259-262
21. Koh GY, Soonpaa MH, Klug MG, Field LJ (1993) Long-term survival of AT-1 cardiomyocyte grafts in syngeneic myocardium. Am J Physiol 264:H1727-1733
22. Kornstein MJ, deBlois GG (1994) Pathology of the thymus and mediastinum. (MPP vol 33, Saunders, Philadelphia
23. Kuo T, Chang JP, Lin FJ, Wu WC, Chang CH (1990) Thymic carcinomas: histopathological varieties and immunohistochemical study. Am J Surg Pathol 14:24-34
24. Kuo TT, Lo SK (1993) Thymoma. A study of the pathologic classification of 71 cases with evaluation of the Muller-Hermelink system. Hum Pathol 24:766-771
25. Levine AJ (1988) Oncogenes of DNA tumour viruses. Cancer Res 48:493-496
26. Levine GD, Rosai J (1978) Thymic hyperplasia and neoplasia: A review of current concepts. Hum Pathol 9:495-515
27. Lu J, Sakai Y, Wajjawalku W, Isobe K-I, Saito M, Amo H, Kojima A, Utsumi KR, Takahashi M, Hiai H, Matsuyama M (1992) Establishment of transplantable tumour lines and in vitro cell lines of malignant thymoma developed in a BUF/Mna rat. Jpn J Cancer Res 83:618-624
28. Mahon KA, Chepelinsky AB, Khillan JS, Overbeek PA, Piatigorsky J, Westphal H (1987) Oncogenesis of the lens in transgenic mice. Science 235:1622-1628
29. Marino M, Muller-Hermelink HK (1985) Thymoma and thymic carcinoma. Relation of thymoma epithelial cells to the cortical and medullary differentiation of thymus. Virchows Arch [A] 407:119-149
30. Masaoka A, Monden Y, Nakahara K, Tanioka T (1981) Follow-up study of thymomus with special reference to their clinical stages. Cancer 48:2485-2492
31. Masuda A, Ohtsuka K, Matsuyama M (1990) Establishment of functional epithelial cell lines from a rat thymoma and a rat thymus. In Vitro Cell Dev Biol 1990, 26:713-721
32. Messing A, Chen HY, Palmiter RD, Brinster RL (1985) Peripheral neuropathies, hepato-cellular carcinomas and islet cell adenomas in transgenic mice. Nature (London) 316:461-463
33. Messing A, Pinkert CA, Palmiter RD, Brinster RL (1988) Developmental study of SV40 large T antigen expression in transgenic mice and choroid plexus neoplasia. Oncogene Res 3:87-97
34. Moll J, Eibel H, Botteri F, Sansig G, Regnier C, Putten H van der (1992) Transgenes encoding mutant simian virus 40 large T antigens unmask phenotypic and functional constraints in thymic epithelial cells. Oncogene 7:2175-2187
35. Morinaga S, Sato Y, Shimosato Y, Sinkai T, Tsuchiya R (1987) Multiple thymic squamous cell carcinomas associated with mixed type thymoma. Am J Surg Pathol 11:982-988
36. Palmiter RD, Chen HY, Messing A, Brinster RL (1985) SV40 enhancer and large T antigen are instrumental in development of choroid plexus tumours in transgenic mice. Nature 316:457-460
37. Pan CC, Wu HP, Yang CF, Chen WYK, Chiang H (1994) The clinicopathological rrelation of epithelial subtyping in thymoma: a study of 112 consecutive cases. Hum Pathol 25:893-899
38. Park WY, Kim JI, Shim EH, Lee WH, Kim SH, Seo JW, Jang JJ, Seo JS (1996) Development of thymic carcinoma in transgenic mice expressing SV40 T antigen. Cancer Lett 107:293-300
39. Pescarmona E, Rendina EA, Venuta F, Ricci C, Ruco LP, Baroni CD (1990) The prognostic implication of the thymoma histologic subtyping. A study of 80 consecutive cases. Am J Clin Pathol 93:190-195
40. Pescarmona E, Pisacane A, Rendina EA (1991) Organoid thymoma: A well differentiated variant with distinct clinicopathological features. Histopathology 18:161-164
41. Pescarmona E, Rosati S, Rendina EA, Venuta F, Baroni CD (1992) Well-differentiated thymic carcinoma: a clinico-pathological study. Virchows Arch [A] 420:179-183
42. Pescarmona E, Rendina EA, Venuta F, Ricci C, Ruco LP, Baroni CD (1995) Recurrent thymoma: evidence for histological progression. Histopathology 27:445-449
43. Quintanilla-Martinez L, Wilkins EW, Choi N, Efird J, Hug E, Harris NL (1994) Thymoma. Histologic subclassification is an independent prognostic factor. Cancer 74:606-617
44. Rosai J, Levine GD (1976) Atlas of tumour pathology, 2nd ser, Fasc 13. Tumours of the thymus. Armed Forces Institute of Pathology, Washington DC, pp 153-161
45. Salyer WR, Eggleston JC (1976) Thymoma: a clinical and pathological study of 65 cases. Cancer 37:229-249
46. Sandgren EP, Quaife CJ, Pinkert CA, Palmiter RD, Brinster RL (1989) Oncogene-induced liver neoplasia in transgenic mice. Oncogene 4:715-724
47. Sepulveda AR, Finegold MJ, Smith B, Slagle BL, DeMayo JL, Shen RF, Woo SL, Butel JS (1989) Development of a transgenic mouse system for the analysis of stages in liver carcinogenesis using tissue-specific expression of SV40 large T-antigen controlled by regulatory elements of the human alpha-1-antitrypsin gene. Cancer Res 49:6108-6117
48. Shimosato Y, Kameya T, Nagai K, Suemasu K (1977) Squamous cell carcinoma of the thymus: an analysis of eight cases. Am J Surg Pathol 1:109-121
49. Small JA, Blair DG, Showalter SD, Scangos GA (1985) Analysis of a transgenic mouse containing simian virus 40 and v-myc sequences. Mol Cell Biol 5:642-648
50. Spanopoulou E, Early A, Elliott J, Crispe N, Layman H, Ritter M, Watt S, Grosveld F, Kioussis D (1989) Complex lymphoid and epithelial thymic tumours in Thy 1-myc transgenic mice. Nature 342:185-189
51. Squire RA, Goodmann DG, Valerio MG, Fredrickson T, Strandherg JD, Levin MH, Lingeman GH, Harshbarger JC, Dawe CJ (1978) Tumours: hemopoietic system. In: Benirschke K, Garner FM, Jones TC (eds) Pathology of laboratory animals. Springer, New York Berlin Heidelberg, pp 1091-1125
52. Suarez-Vilela D, Salas Valien JS, Gonzales Moran MA, Izquierdo Garcia F, Riero Velasco JR (1992) Thymic carcinosarcoma associated with spindle cell thymoma: an immunohisto-chemical study. Histopathology 21:263-268
53. Suda Y, Aizawa S, Hirai S, Inoue T, Furuta Y, Suzuki M, Hirohashi S, Ikawa Y (1987) Driven by the same Ig enhancer and SV40T promoter, ras induced lung adenomatous tumours, myc induced pre-B cell lymphomas and SV40 large T gene a variety of tumours in transgenic mice. EMBO J 6:4055-4065
54. Suster S, Moran CA (1996) Primary thymic epithelial neoplasms showing combined features of thymoma and thymic carcinoma: a clinicopathologic study of 22 cases. Am J Surg Pathol 20:1469-1480
55. Suster S, Rosai J (1991) Thymic carcinoma. A clinicopathologic study of 60 cases. Cancer 67:1025-1032
56. Teitelman G, Alpert S, Hanahan D (1988) Proliferation, senescence, and neoplastic progression of cells in hyperplasic pancreatic islets. Cell 52:97-105
57. Teitz T, Chang JC, Kan YW, Yen TSB (1995) Thymic epithelial neoplasms in transgenic mice expressing SV40 T antigen under the control of an erythroid-specific enhancer. J Pathol (Lond) 177:309-315
58. Troung LD, Mody DR, Cagle PT, Jackson-York GL, Schwartz MR, Wheeler TM (1990) Thymic carcinoma: a clinicopathologic study of 13 cases. Am J Surg Pathol 14:151-166
59. Van Dyke TA, Finlay C, Miller D, Marks J, Lozano G, Levine AJ (1987) Relationship between simian virus 40 large tumour antigen expression and tumour formation in transgenic mice. J Virol 61:2029-2032
60. Wick MR, Weiland LH, Scheithauer BZ, Bernatz PE (1982) Primary thymic carcinomas. Am J Surg Pathol 6:613-630
61. Windle JJ, Albert DM, Obien JM, Marcus DM, Disteche CM, Bernards R, Mellon PL (1990) Retinoblastoma in transgenic mice. Nature 343:665-669