-
1
-
-
0642347852
-
Polo-like kinases and the microtubule organization center: Targets for cancer therapies
-
Dai W, Cogswell JP. Polo-like kinases and the microtubule organization center: targets for cancer therapies. Prog Cell Cycle Res 2003;5:327-34.
-
(2003)
Prog Cell Cycle Res
, vol.5
, pp. 327-334
-
-
Dai, W.1
Cogswell, J.P.2
-
2
-
-
1642403866
-
Polo-like kinase isoform expression is a prognostic factor in ovarian carcinoma
-
Weichert W, Denkert C, Schmidt M, et al. Polo-like kinase isoform expression is a prognostic factor in ovarian carcinoma. Br J Cancer 2004;90:815-21.
-
(2004)
Br J Cancer
, vol.90
, pp. 815-821
-
-
Weichert, W.1
Denkert, C.2
Schmidt, M.3
-
3
-
-
17644368237
-
ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent
-
Gumireddy K, Reddy MV, Cosenza SC, et al. ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent. Cancer Cell 2005;7:275-86.
-
(2005)
Cancer Cell
, vol.7
, pp. 275-286
-
-
Gumireddy, K.1
Reddy, M.V.2
Cosenza, S.C.3
-
4
-
-
16344367736
-
Silencing of polo-like kinase (Plk) 1 via si RNA causes induction of apoptosis and impairment of mitosis machinery in human prostate cancer cells: Implications for the treatment of prostate cancer
-
Reagan-Shaw S, Ahmad N. Silencing of polo-like kinase (Plk) 1 via si RNA causes induction of apoptosis and impairment of mitosis machinery in human prostate cancer cells: implications for the treatment of prostate cancer. FASEB J 2005;19:611-3.
-
(2005)
FASEB J
, vol.19
, pp. 611-613
-
-
Reagan-Shaw, S.1
Ahmad, N.2
-
5
-
-
13244253709
-
Differential regulation of polo-like kinase 1, 2, 3, and 4 gene expression in mammalian cells and tissues
-
Winkles JA, Alberts GF. Differential regulation of polo-like kinase 1, 2, 3, and 4 gene expression in mammalian cells and tissues. Oncogene 2005;24:260-6.
-
(2005)
Oncogene
, vol.24
, pp. 260-266
-
-
Winkles, J.A.1
Alberts, G.F.2
-
6
-
-
18344366048
-
Getting in and out of mitosis with Polo-like kinase-1
-
Van Vugt MA, Medema RH. Getting in and out of mitosis with Polo-like kinase-1. Oncogene 2005;24: 2844-59.
-
(2005)
Oncogene
, vol.24
, pp. 2844-2859
-
-
Van Vugt, M.A.1
Medema, R.H.2
-
7
-
-
0034722892
-
Replication-selective oncolytic adenoviruses: Virotherapy aimed at genetic targets in cancer
-
Kirn D. Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer. Oncogene 2000;19:6660-9.
-
(2000)
Oncogene
, vol.19
, pp. 6660-6669
-
-
Kirn, D.1
-
8
-
-
4143092630
-
Use of replicating oncolytic adenoviruses in combination therapy for cancer
-
Chu RL, Post DE, Khuri FR, Van Meir EG. Use of replicating oncolytic adenoviruses in combination therapy for cancer. Clin Cancer Res 2004;10:5299-312.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5299-5312
-
-
Chu, R.L.1
Post, D.E.2
Khuri, F.R.3
Van Meir, E.G.4
-
9
-
-
0033831080
-
A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
-
Khuri FR, Nemunaitis J, Ganly J, et al. A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 2000;6:879-85.
-
(2000)
Nat Med
, vol.6
, pp. 879-885
-
-
Khuri, F.R.1
Nemunaitis, J.2
Ganly, J.3
-
10
-
-
0034610723
-
A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo
-
Fueyo J, Gomez-Manzano C, Alemany R, et al. A mutant oncolytic adenovirus targeting the Rb pathway produces anti-glioma effect in vivo. Oncogene 2000; 19:2-12.
-
(2000)
Oncogene
, vol.19
, pp. 2-12
-
-
Fueyo, J.1
Gomez-Manzano, C.2
Alemany, R.3
-
11
-
-
0033782862
-
An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy
-
Heise C, Hermiston C, Johnson L, et al. An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy. Nat Med 2000;6:1134-9.
-
(2000)
Nat Med
, vol.6
, pp. 1134-1139
-
-
Heise, C.1
Hermiston, C.2
Johnson, L.3
-
12
-
-
0142219877
-
A prodrug strategy using ONYX-015-based replicating adenoviruses to deliver rabbit carboxylesterase to tumor cells for conversion of CPT-11 to SN-38
-
Stubdal H, Perin N, Lemmon M, et al. A prodrug strategy using ONYX-015-based replicating adenoviruses to deliver rabbit carboxylesterase to tumor cells for conversion of CPT-11 to SN-38. Cancer Res 2003; 63:6900-8.
-
(2003)
Cancer Res
, vol.63
, pp. 6900-6908
-
-
Stubdal, H.1
Perin, N.2
Lemmon, M.3
-
13
-
-
0035893397
-
Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase
-
Nanda D, Vogels R, Havenga M, Avezaat CJ, Bout A, Smitt PS. Treatment of malignant gliomas with a replicating adenoviral vector expressing herpes simplex virus-thymidine kinase. Cancer Res 2001;61:8743-50.
-
(2001)
Cancer Res
, vol.61
, pp. 8743-8750
-
-
Nanda, D.1
Vogels, R.2
Havenga, M.3
Avezaat, C.J.4
Bout, A.5
Smitt, P.S.6
-
14
-
-
17944371743
-
Gene delivery from the E3 region of replicating human adenovirus: Evaluation of the 6.7K/gp19K region
-
Hawkins LK, Johnson L, Bauzon M, et al. Gene delivery from the E3 region of replicating human adenovirus: evaluation of the 6.7K/gp19K region. Gene Ther 2001;8:1123-31.
-
(2001)
Gene Ther
, vol.8
, pp. 1123-1131
-
-
Hawkins, L.K.1
Johnson, L.2
Bauzon, M.3
-
15
-
-
70350546842
-
Isolation, growth, and purification of defective adenovirus deletion mutants
-
Wold WSM, editor. Totowa (NJ): Humana Press
-
Gary K, Boyer J. Isolation, growth, and purification of defective adenovirus deletion mutants. In: Wold WSM, editor. Adenovirus methods and protocols. Totowa (NJ): Humana Press; 1999. p. 25-32.
-
(1999)
Adenovirus Methods and Protocols
, pp. 25-32
-
-
Gary, K.1
Boyer, J.2
-
16
-
-
0006738608
-
Construction of mutations in the adenovirus early region 3 (E3) transcription units
-
Wold WSM, editor. Totowa (NJ): Humana Press
-
Hermiston TW, Tollefson AE, Wold WSM. Construction of mutations in the adenovirus early region 3 (E3) transcription units. In: Wold WSM, editor. Adenovirus methods and protocols. Totowa (NJ): Humana Press; 1999. p. 11-24.
-
(1999)
Adenovirus Methods and Protocols
, pp. 11-24
-
-
Hermiston, T.W.1
Tollefson, A.E.2
Wold, W.S.M.3
-
17
-
-
0030815119
-
Inhibition of metastasis of intraocular melanomas by adenovirus-mediated gene transfer of plasminogen activator inhibitor type 1 (PAI-1) in an athymic mouse model
-
Ma D, Gerard RD, Li XY, et al. Inhibition of metastasis of intraocular melanomas by adenovirus-mediated gene transfer of plasminogen activator inhibitor type 1 (PAI-1) in an athymic mouse model. Blood 1997;90: 2738-46.
-
(1997)
Blood
, vol.90
, pp. 2738-2746
-
-
Ma, D.1
Gerard, R.D.2
Li, X.Y.3
-
18
-
-
0035266249
-
Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: An epithelialstromal interaction in breast tumors mediated by CCAAT/enhancer binding protein β
-
Zhou J, Gurates B, Yang S, et al. Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelialstromal interaction in breast tumors mediated by CCAAT/enhancer binding protein β. Cancer Res 2001;61:2328-34.
-
(2001)
Cancer Res
, vol.61
, pp. 2328-2334
-
-
Zhou, J.1
Gurates, B.2
Yang, S.3
-
19
-
-
0037147159
-
PTP1B modulates the association of β-catenin with N-cadherin through binding to an adjacent and partially overlapping target site
-
Xu G, Arregui C, Lilien J, et al. PTP1B modulates the association of β-catenin with N-cadherin through binding to an adjacent and partially overlapping target site. J Biol Chem 2002;277: 49989-97.
-
(2002)
J Biol Chem
, vol.277
, pp. 49989-49997
-
-
Xu, G.1
Arregui, C.2
Lilien, J.3
-
20
-
-
7044246181
-
Nude mice model of human hepatocellular carcinoma via orthotopic implantation of histologically intact tissue
-
Gao YS, Chen XP, Li KY, et al. Nude mice model of human hepatocellular carcinoma via orthotopic implantation of histologically intact tissue. World J Gastroenterol 2004;10:3107-11.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 3107-3111
-
-
Gao, Y.S.1
Chen, X.P.2
Li, K.Y.3
-
21
-
-
4944242884
-
A vision for the national cancer program in the United States
-
Von Eschenbach AC. A vision for the national cancer program in the United States. Nat Rev Cancer 2004;4: 820-8.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 820-828
-
-
Von Eschenbach, A.C.1
-
22
-
-
0034909752
-
Human papillomavirus E6 E7-mediated adenovirus cell killing: Selectivity of mutant adenovirus replication in organo-typic cultures of human keratinocytes
-
Balagué C, Noya F, Alemany R, et al. Human papillomavirus E6 E7-mediated adenovirus cell killing: selectivity of mutant adenovirus replication in organo-typic cultures of human keratinocytes. J Virol 2001;75: 7602-11.
-
(2001)
J Virol
, vol.75
, pp. 7602-7611
-
-
Balagué, C.1
Noya, F.2
Alemany, R.3
-
23
-
-
0035913202
-
Images in clinical medicine. Liver metastases from lung cancer
-
Baron M, Lewis V. Images in clinical medicine. Liver metastases from lung cancer. N Engl J Med 2001; 345:180.
-
(2001)
N Engl J Med
, vol.345
, pp. 180
-
-
Baron, M.1
Lewis, V.2
-
24
-
-
0034682167
-
Hepatic arterial infusion of chemotherapy for metastatic colorectal cancer
-
Lorenz M, Hochmuth K, Muller HH. Hepatic arterial infusion of chemotherapy for metastatic colorectal cancer. N Engl J Med 2000;342:1525-6.
-
(2000)
N Engl J Med
, vol.342
, pp. 1525-1526
-
-
Lorenz, M.1
Hochmuth, K.2
Muller, H.H.3
-
25
-
-
0033619892
-
Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer
-
Kemeny N, Huang Y, Cohen AM, et al. Hepatic arterial infusion of chemotherapy after resection of hepatic metastases from colorectal cancer. N Engl J Med 1999;341:2039-48.
-
(1999)
N Engl J Med
, vol.341
, pp. 2039-2048
-
-
Kemeny, N.1
Huang, Y.2
Cohen, A.M.3
-
26
-
-
0345299824
-
Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis
-
Mazzaferro V, Regalia E, Doci R, et al. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 1996; 334:693-700.
-
(1996)
N Engl J Med
, vol.334
, pp. 693-700
-
-
Mazzaferro, V.1
Regalia, E.2
Doci, R.3
-
27
-
-
0036401152
-
Adenovirus biodistribution and noninvasive imaging of gene expression in vivo by positron emission tomography using human sodium/iodide symporter as reporter gene
-
Groot-Wassink T, Aboagye EO, Glaser M, et al. Adenovirus biodistribution and noninvasive imaging of gene expression in vivo by positron emission tomography using human sodium/iodide symporter as reporter gene. Hum Gene Ther 2002;13:1723-35.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1723-1735
-
-
Groot-Wassink, T.1
Aboagye, E.O.2
Glaser, M.3
-
28
-
-
0035188302
-
Intravascular injections of a conditional replicative adenovirus (adl118) prevent metastatic disease in human breast carcinoma xenografts
-
Fabra A, Parada C, Vinyals A, et al. Intravascular injections of a conditional replicative adenovirus (adl118) prevent metastatic disease in human breast carcinoma xenografts. Gene Ther 2001;8:1627-34.
-
(2001)
Gene Ther
, vol.8
, pp. 1627-1634
-
-
Fabra, A.1
Parada, C.2
Vinyals, A.3
-
29
-
-
0035835373
-
E1B-deleted adenovirus (dl1520) gene therapy for patients with primary and secondary liver tumors
-
Habib NA, Sarraf CE, Mitry RR, et al. E1B-deleted adenovirus (dl1520) gene therapy for patients with primary and secondary liver tumors. Hum Gene Ther 2001;12:219-26.
-
(2001)
Hum Gene Ther
, vol.12
, pp. 219-226
-
-
Habib, N.A.1
Sarraf, C.E.2
Mitry, R.R.3
-
30
-
-
0037087621
-
Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer
-
Vasey PA, Shulman LN, Campos S, et al. Phase I trial of intraperitoneal injection of the E1B-55-kd-gene-deleted adenovirus ONYX-015 (dl1520) given on days 1 through 5 every 3 weeks in patients with recurrent/refractory epithelial ovarian cancer. J Clin Oncol 2002; 20:1562-9.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1562-1569
-
-
Vasey, P.A.1
Shulman, L.N.2
Campos, S.3
-
31
-
-
10744227813
-
Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer
-
Freytag SO, Stricker H, Pegg J, et al. Phase I study of replication-competent adenovirus-mediated double-suicide gene therapy with conventional-dose three-dimensional conformal radiation therapy for the treatment of newly diagnosed, intermediate- to high-risk prostate cancer. Cancer Res 2003;63: 7497-506.
-
(2003)
Cancer Res
, vol.63
, pp. 7497-7506
-
-
Freytag, S.O.1
Stricker, H.2
Pegg, J.3
-
32
-
-
0035863458
-
Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer
-
Nemunaitis J, Khuri F, Ganly I, et al. Phase II trial of intratumoral administration of ONYX-015, a replication-selective adenovirus, in patients with refractory head and neck cancer. J Clin Oncol 2001;19:289-98.
-
(2001)
J Clin Oncol
, vol.19
, pp. 289-298
-
-
Nemunaitis, J.1
Khuri, F.2
Ganly, I.3
-
33
-
-
0033693231
-
Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: A phase II trial
-
Nemunaitis J, Ganly I, Khuri F, et al. Selective replication and oncolysis in p53 mutant tumors with ONYX-015, an E1B-55kD gene-deleted adenovirus, in patients with advanced head and neck cancer: a phase II trial. Cancer Res 2000;60:6359-66.
-
(2000)
Cancer Res
, vol.60
, pp. 6359-6366
-
-
Nemunaitis, J.1
Ganly, I.2
Khuri, F.3
-
34
-
-
0036828125
-
Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): Phase II viral, immunologic, and clinical endpoints
-
Reid T, Galanis E. Abbruzzese J, et al. Hepatic arterial infusion of a replication-selective oncolytic adenovirus (dl1520): phase II viral, immunologic, and clinical endpoints. Cancer Res 2002;62:6070-9.
-
(2002)
Cancer Res
, vol.62
, pp. 6070-6079
-
-
Reid, T.1
Galanis, E.2
Abbruzzese, J.3
-
35
-
-
1542360681
-
Factors involved in the sensitivity of different hematopoietic cell lines to infection by subgroup C adenovirus: Implication for gene therapy of human lymphocytic malignancies
-
Colin M, Renaut L, Mailly L, et al. Factors involved in the sensitivity of different hematopoietic cell lines to infection by subgroup C adenovirus: implication for gene therapy of human lymphocytic malignancies. Virology 2004;320:23-39.
-
(2004)
Virology
, vol.320
, pp. 23-39
-
-
Colin, M.1
Renaut, L.2
Mailly, L.3
|