The cysteinyl-leukotriene-1 receptor antagonist zafirlukast is a potent secretagogue in rat and human airways

European Journal of Pharmacology

Volumn 527, Issue 1-3, 2005, Pages 150-156

  Schmidt, Rene ^a   Staats, Petra ^b   Groneberg, David A ^c   Wagner, Ulrich ^b  

^a UNIVERSITY OF FREIBURG   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

Airway mucus; Asthma; COPD (chronic obstructive pulmonary disease); Leukotriene receptor antagonist; Secretion

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3 [3 TERT BUTYLTHIO 1 (4 CHLOROBENZYL) 5 ISOPROPYL 2 INDOLYL] 2,2 DIMETHYLPROPIONIC ACID; ARACHIDONIC ACID; CYSTEINYL LEUKOTRIENE 1 RECEPTOR ANTAGONIST; IBUPROFEN; ICOSATETRAENOIC ACID; MONTELUKAST; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROSTAGLANDIN SYNTHASE; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG; ZAFIRLUKAST;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHUS; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TRACHEA;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 5,8,11,14-EICOSATETRAYNOIC ACID; ACETATES; ANIMALS; ARACHIDONIC ACID; BRONCHI; CHROMONES; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IBUPROFEN; INDOLES; LEUKOTRIENE ANTAGONISTS; LIPOXYGENASE INHIBITORS; MALE; MEMBRANE PROTEINS; MORPHOLINES; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, LEUKOTRIENE; TOSYL COMPOUNDS; TRACHEA;

EID: 28544436014     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.08.064     Document Type: Article

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