A mild, efficient and improved protocol for the synthesis of novel indolyl crown ethers, di(indolyl)pyrazolyl methanes and 3-alkylated indoles using H 4[Si(W3O10)3]

Tetrahedron

Volumn 61, Issue 52, 2005, Pages 12275-12281

  Murugan, Rajendran ^a   Karthikeyan, Murugesan ^a   Perumal, Paramasivam T ^a   Reddy, Boreddy S R ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

Author keywords

3 Alkylated indoles; Di(indolyl)pyrazolyl methanes; Indolyl crown ether; Michael addition

Indexed keywords

1 [2 [2 [2 [2 (1H INDOL 1 YL)ETHOXY]ETHOXY]ETHOXY]ETHYL] 1H INDOLE; 1 METHYL 3 [(1 METHYL 1H INDOL 3 YL)(3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL)METHYL] 1H INDOLE; 1 METHYL 3 [(1 METHYL 1H INDOL 3 YL)(3 PHENYL 1H PYRAZOL 4 YL)METHYL] 1H INDOLE; 2 METHYL 3 [(2 METHYL 1H INDOL 3 YL)(3 PHENYL 1H PYRAZOL 4 YL)METHYL] 1H INDOLE; 3 [1H INDOL 3 YL (3 PHENYL 1H PYRAZOL 4 YL)METHYL] 1H INDOLE; 3 [1H INDOL 3 YL [3 (3 METHOXYPHENYL) 1H PYRAZOL 4 YL]METHYL] 1H INDOLE; 3 [1H INDOL 3 YL [3 (4 CHLOROPHENYL) 1H PYRAZOL 4 YL]METHYL] 1H INDOLE; 3 [1H INDOL 3 YL [3 (4 METHOXYPHENYL) 1H PYRAZOL 4 YL]METHYL] 1H INDOLE; 5 METHOXY 3 [(5 METHOXY 1H INDOL 3 YL)(3 PHENYL 1H PYRAZOL 4 YL)METHYL] 1H INDOLE; CROWN ETHER DERIVATIVE; INDOLE DERIVATIVE; METHANE; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CATALYST; CHEMICAL REACTION; CRYSTAL STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; MICHAEL ADDITION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; X RAY ANALYSIS;

EID: 28444493624     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2005.09.108     Document Type: Article

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42. 3; crystal system: triclinic; space group: Pī (#4); unit cell: a=10.4646(9) Å, b=15.3530(13) Å, c=18.8220(16) Å, α=101.008(1)°, β=106.060(1)°, γ=98.345(1)°.