Amberlyst 15 catalyzed synthesis of indole-pyrazole based tri(hetero)arylmethanes

Tetrahedron Letters

Volumn 45, Issue 26, 2004, Pages 5099-5102

  Farhanullah, ^a   Sharon, Ashoke ^a   Maulik, Prakas R ^a   Ram, Vishnu Ji ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Amberlyst 15; Coupling reaction; Tripodal heterocycles

Indexed keywords

ALKANE DERIVATIVE; INDOLE DERIVATIVE; METHANE; PYRAZOLE DERIVATIVE;

ARTICLE; CATALYSIS; CROSS COUPLING REACTION; DRUG SYNTHESIS; POLYMERIZATION; QUANTUM YIELD; REACTION ANALYSIS;

STAPHYLOCOCCUS PHAGE 3A;

EID: 2942657039     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.04.172     Document Type: Article

References (26)

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24. Typical procedure for 3: A mixture of indole 1 (4.03 mmol) and 4-formylpyrazole 2 (2.01 mmol) in chloroform (15 mL) was stirred for 0.5-1 h in the presence of Amberlyst 15 (141 mg) at ambient temperature. The precipitate along with the catalyst was filtered off, washed with chloroform (10 mL). The solid obtained was dissolved in acetone and filtered to separate the catalyst. The filtrate was concentrated to the appropriate volume and left for crystallization
25. 2. Programs: XSCANS [(Siemens Analytical X-ray Instruments Inc.: Madison, Wisconsin, USA 1996) were used for data collection and data processing], SHELXTL-NT [(Bruker AXS Inc.: Madison, Wisconsin, USA 1997) was used for structure determination, refinements and molecular graphics]. Further details of the crystal structure investigation can be obtained from the Cambridge Crystallographic Data Centre, 12 Union Road, Cambridge, CB21EZ, UK (CCDC deposit No: 178524)
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