Accelerating perfusion process optimization by scanning non-steady-state responses

Biotechnology and Bioengineering

Volumn 92, Issue 4, 2005, Pages 472-478

  Angepat, Sumitra ^a,b,c   Gorenflo, Volker M ^a,b,d   Piret, James M ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c ABBOTT LABORATORIES   (United States)

^d Sanofi Pasteur   (Canada)

Author keywords

CHO; Mammalian cell culture; Perfusion; Process optimization; t PA; Transient

Indexed keywords

BIOTECHNOLOGY; OPTIMIZATION;

CHO; MAMMALIAN CELL CULTURE; PERFUSION; PROCESS OPTIMIZATION; T-PA; TRANSIENT;

CELL CULTURE;

TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL CELL; ARTICLE; BIOTECHNOLOGY; CELL CULTURE; CELL DENSITY; CHO CELL; CONCENTRATION RESPONSE; NONHUMAN; PERFUSION PROCESS; PREDICTION; PROCESS DESIGN; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PRODUCTIVITY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; STEADY STATE; TEMPERATURE MEASUREMENT;

ANIMALS; CELL CULTURE TECHNIQUES; CHO CELLS; CRICETINAE; CRICETULUS; HEAT; HUMANS; PERFUSION; RECOMBINANT PROTEINS; TISSUE PLASMINOGEN ACTIVATOR;

ANIMALIA; MAMMALIA;

EID: 28444463599     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/bit.20635     Document Type: Article

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