Ophthalmic delivery systems based on drug-polymer-polymer ionic ternary interaction: In vitro and in vivo characterization

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 62, Issue 1, 2006, Pages 59-69

  Sandri, Giuseppina ^a   Bonferoni, Maria Cristina ^a   Chetoni, Patrizia ^b   Rossi, Silvia ^a   Ferrari, Franca ^a   Ronchi, Celestino ^c   Caramella, Carla ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c Monteresearch SpA   (Italy)

Author keywords

Chitosan; Drug release properties, Ex vivo in vivo residence properties; Gelatin; Hyaluronic acid; Mucoadhesion properties; Physical stability; Polyacrylic acid; Steam sterilization; Tetrahydrozoline hydrochloride

Indexed keywords

CHITOSAN; GELATIN; HYALECTINE; HYALURONIC ACID; POLYACRYLIC ACID; TETRYZOLINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONJUNCTIVA; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG POTENTIATION; DRUG STABILITY; MALE; NONHUMAN; TEMPERATURE DEPENDENCE; VISCOSITY;

ACRYLIC RESINS; ADHESIVENESS; ADHESIVES; ANIMALS; CHEMISTRY, PHARMACEUTICAL; CHITOSAN; DRUG DELIVERY SYSTEMS; DRUG STABILITY; GASTRIC MUCIN; GASTRIC MUCINS; HYALURONIC ACID; IMIDAZOLES; MALE; OPHTHALMIC SOLUTIONS; POLYMERS; RABBITS; TEMPERATURE; TIME FACTORS; VISCOSITY;

EID: 28444451554     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2005.07.002     Document Type: Article

References (27)

1. S.-D. Jaanus Ocular inflammatory disease: pharmacological update Clin. Eye Vis. Care 11 1999 3 12
2. M. Bisca Current therapy of allergic conjunctivitis Curr. Ther, Res. 58 1997 828 841
3. H. Sasaki, K. Yamamura, K. Nishida, J. Nakamura, and M. Ichikawa Delivery of drugs to eye by topical application, in: ocular drug delivery systems, cap 11 Prog. Retin. Eye Res. 15 1996 583 620
4. C. Le Bourlais, L. Acar, H. Zia, P.-A. Sado, T. Needham, and R. Laverge Ophthalimic drug delivery systems-Recent advance Prog. Ret. Eye Res. 17 1998 33 58
5. K.-L. Goa, and P. Benfield Hyaluronic acid: a review of its pharmacology and use as surgical aid in ophthalmology and its therapeutic potential in joint disease and wound healing Drugs 47 1994 536 566
6. M.-F. Saettone, D. Monti, M.-T. Torracca, and P. Chetoni Mucoadhesive ophthalimic vehicles: evaluation of polymeric low-viscosity formulations J. Ocular Pharmacol. 10 1994 82 92
7. C.-M. Lehr, J.-A. Bouwstra, E.-H. Schacht, and H.-E. Junginger In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers Int. J. Pharm. 78 1992 43 48
8. I. Henriksen, K.-L. Green, J.-D. Smart, G. Smistad, and J. Karlsen Bioadhesion of hydrated chitosans: an in vitro and in vivo study Int. J. Pharm. 145 1996 231 240
9. O. Felt, P. Furrer, J.-M. Mayer, B. Plazonnet, P. Buri, and R. Gurny Topical use of chitosan in ophthalmology: tolerance assessment and precorneal retention Int. J. Pharm. 180 1999 185 193
10. M.-C. Bonferoni, P. Chetoni, P. Giunchedi, S. Rossi, F. Ferrari, S. Burgalassi, and C. Caramella Carrageenan-gelatin mucoadhesive systems for ion-exchange based ophthalmic delivery: in vitro and preliminary in vivo studies Eur. J. Pharm. Biopharm. 57 2004 465 472
11. J. Ceulemans, and A. Ludwig Optimization of carbomer viscous eye drops: an in vivo experimental design approach using rheological technique Eur. J. Pharm. Biopharm. 54 2002 41 50
12. B.-S. Lele, and A.-S. Hoffman Insoluble ionic complexes of polyacrylic acid with a cationic drug for use as a mucoadhesive, ophthalmic drug delivery system J. Biomat. Sci. 11 2000 1319 1331
13. J.-M. Yanni, N.-A. Sharif, D.-A. Garmache, S.-T. Miller, L.-K. Weimer, and J.-M. Spellman A current appreciation of sites for pharmacological intervention in allergic conjunctivitis: effects of new topical ocular drugs Acta Ophthalmol. Scand. 77 1999 33 37
14. M.-C. Bonferoni, S. Rossi, F. Ferrari, G.-P. Bettinetti, and C. Caramella Characterization of diltiazem-lamba carrageenan complex Int. J. Pharm. 200 2000 207 216
15. M.-C. Bonferoni, S. Rossi, F. Ferrari, and C. Caramella Development of oral controlled-release tablet formulations based on diltiazem-carrageenan complex Pharm. Dev. Technol. 9 2004 155 162
16. I.-M. Klotz, F.-M. Walker, and R.-B. Pivan The binding of organic ions with proteins J. Am. Chem. Soc. 68 1946 1486 1490
17. S. Rossi, F. Ferrari, M.-C. Bonferoni, and C. Caramella Characterization of chitosan hydrocloride-mucin interaction by means of viscosimetric and turbidimetric mesurements Eur. J. Pharm. Sci. 12 2000 251 257
18. I. Genta, B. Conti, P. Perugini, F. Pavanetto, A. Spadaro, and G. Pugliesi Bioadhesive microspheres of ophthalmic administration of acyclovir J. Pharm. Pharmacol. 49 1997 737 742
19. C. Caramella, M.-C. Bonferoni, S. Rossi, and F. Ferrari Rheological and tensile tests for the assessment of polymer-mucin interactions Eur. J. Pharm. Biopharm. 40 1994 213 217
20. F. Ferrari, S. Rossi, M.-C. Bonferoni, M. Bertoni, C. Caramella, M.-J. Warig, and M.-E. Aulton Comparative rheomechanical and adhesive properties of two hydrocolloid dressings. Dependence on the degree of hydration Drug Dev. Ind. Pharm. 22 1996 1223 1230
21. M. Albasini, and A. Ludwig Evaluation of polysaccharides intended for opthalmic use in ocular dosage forms Il Farmaco 50 1995 27 37
22. M.-C. Bonferoni, S. Rossi, F. Ferrari, and C. Caramella A modified cell for simultaneous assessment of drug release and washability of mucoadhesive gels Pharm. Dev. Technol. 4 1999 45 53
23. S. Rossi, M.-C. Bonferoni, F. Ferrari, and C. Caramella Drug release and washability of mucoadhesive gels based on sodium carboxymethylcellulose and polyacrylic acid Pharm. Dev. Technol. 4 1999 55 63
24. C.-R. Park, and D.-L. Munday Development and evaluation of abiphasic buccal adhesive tablet for nicotine replacement therapy Int. J. Pharm. 237 2002 215 226
25. G. Andermann, and A. Richard Stability-indicating determination of tetrahydrozoline hydrochloride in ophthalmic solutions by high-performance liquid chromatography J. Chromatogr. 298 1985 189 192
26. A. Bindal, G. Narsimhan, S.-L. Hem, and A. Kulshreshtha Effect of steam sterilization on the rheology of polymer solutions Pharm. Dev. Technol. 8 2003 219 228
27. W. Weyenberg, V. Torodov, and A. Ludwig Rheological evaluation of the influence of sterilization on ocular gels using an experimental design Pharmazie 59 2004 121 125