Coagulation cascade activation causes CC chemokine receptor-2 gene expression and mononuclear cell activation in hemodialysis patients

Journal of the American Society of Nephrology

Volumn 16, Issue 8, 2005, Pages 2477-2486

  Pertosa, Giovanni ^a   Simone, Simona ^a   Soccio, Michela ^a   Marrone, Daniela ^a   Gesualdo, Loreto ^b   Schena, Francesco Paolo ^a   Grandaliano, Giuseppe ^a  

^a UNIVERSITY OF BARI   (Italy)

^b UNIVERSITY OF FOGGIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; BLOOD CLOTTING FACTOR 10A; CELLULOSE ACETATE; CHEMOKINE RECEPTOR CCR2; ETHYLENE VINYL ALCOHOL COPOLYMER; MESSENGER RNA; PROTEIN TYROSINE KINASE; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 4; THROMBIN RECEPTOR;

ADULT; ARTICLE; BLOOD CLOTTING; CELL ACTIVATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HEMODIALYSIS; HUMAN; HUMAN CELL; LEUKOCYTE COUNT; MALE; MONOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RECEPTOR GENE; UPREGULATION;

EID: 28444444484     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2004070621     Document Type: Article

References (37)

1. Gesualdo L, Pertosa G, Grandaliano G, Schena FP: Cytokines and bioincompatibility. Nephrol Dial Transplant 13: 1622-1626, 1998
2. Sagedal S, Hartmann A, Sundstrom K, Bjornsen S, Brosstad F: Anticoagulation intensity sufficient for haemodialysis does not prevent activation of coagulation and platelets. Nephrol Dial Transplant 16: 987-993, 2001
3. Gasic GP, Arenas CP, Gasic TB, Gasic GJ: Coagulation factors X, Xa and protein S as a potent mitogens of cultured aortic smooth muscle cells. Proc Natl Acad Sci U S A 89: 2317-2320, 1992
4. Ko FN, Yang YC, Huang SC, Ou JT: Coagulation factor Xa stimulates platelet-derived growth factor release and mitogenesis in cultured vascular smooth muscle cells of rat. J Clin Invest 98: 1493-1501, 1996
5. Papapetropoulos A, Piccardoni P, Cirino G, Bucci M, Sorrentino R, Cicala C, Johnson K, Zachariou V, Sessa WC, Altieri DC: Hypotension and inflammatory cytokine gene expression triggered by factor Xa-nitric oxide signaling. Proc Natl Acad Sci U S A 95: 4738-4742, 1998
6. Altieri DC, Edgington TS. Identification of effector cell protease receptor-1: A leukocyte-distributed receptor for the serine protease factor Xa. J Immunol 145: 246-253, 1990
7. Bono F, Schaeffer P, Hérault J-P, Michaux C, Nestor AL, Guillemot JC, Herbert JM: Factor Xa activates endothelial cells by a receptor cascade between EPR-1 and PAR-2. Arterioscler Thromb Vasc Biol 20: 107-112, 2000
8. Coughlin SR. Protease-activated receptors start a family. Proc Natl Acad Sci U S A 91: 9200-9202, 1994
9. Nystedt S, Emilsson K, Wahlestedt C, Sundelin J: Molecular cloning of a potential proteinase activated receptor. Proc Natl Acad Sci U S A 91: 9208-9212, 1994
10. Vu TK, Hung DT, Wheaton VI, Coughlin SR: Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. Cell 64: 1057-1068, 1991
11. Leonard EJ, Yoshimura T: Human monocyte chemoattractant protein-1 (MCP-1). Immunol Today 11: 97-101, 1990
12. Pertosa G, Grandaliano G, Gesualdo L, Ranieri E, Monno R, Schena FP: Interleukin-6, interleukin-8 and monocyte chemotactic peptide-1 gene expression and protein synthesis are independently modulated by hemodialysis membranes. Kidney Int 54: 570-579, 1998
13. Grandaliano G, Valente AJ, Abboud HE: A novel biologic effect of thrombin: Stimulation of monocyte chemotactic peptide-1 production. J Exp Med 179: 1737-1741, 1994
14. Colotta F, Sciacca FL, Sironi M, Luini W, Rabiet MJ, Mantovani A: Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin. Am J Pathol 144: 975-985, 1994
15. Charo IF, Myers SJ, Herman A, Franci C, Connolly AJ, Coughlin SR: Molecular cloning and functional expression of two monocyte chemoattractant protein 1 receptors reveals alternative splicing of the carboxyl-terminal tails. Proc Natl Acad Sci U S A 91: 2752-2756, 1994
16. Kurihara T, Bravo R: Cloning and functional expression of mCCR2, a murine receptor for the C-C chemokines JE and FIC. J Biol Chem 271: 11603-11607, 1996
17. Rayner K, Van Eersel S, Groot PH, Reape TJ: Localisation of mRNA for JE/MCP-1 and its receptor CCR2 in atherosclerotic lesions of the ApoE knockout mouse. J Vasc Res 37: 93-102, 2000
18. Boring L, Gosling J, Cleary M, Charo IF: Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis. Nature 394: 894-897, 1998
19. Ishii Y, Yano S, Kanai H, Maezawa A, Tsuchida A, Wakamatsu R, Naruse T: Evaluation of blood coagulation-fibrinolysis system in patients receiving chronic hemodialysis. Nephron 73: 407-412, 1996
20. Pertosa G, Grandaliano G, Gesualdo L, Schena FP: Clinical relevance of cytokine production in hemodialysis. Kidney Int Suppl 76: S104-S111, 2000
21. Pertosa G, Tarantino EA, Gesualdo L, Montinaro V, Schena FP: C5b-9 generation and cytokine production in hemodialysed patients. Kidney Int Suppl 43: S221-S225, 1993
22. Rus HG, Niculescu FI, Shin ML: Role of the C5b-9 complement complex in cell cycle and apoptosis. Immunol Rev 180: 49-55, 2001
23. Viedt C, Hansch GM, Brandes RP, Kubler W, Kreuzer J: The terminal complement complex C5b-9 stimulates interleukin-6 production in human smooth muscle cells through activation of transcription factors NF-kB and AP-1. FASEB J 14: 2370-2372, 2000
24. Hofbauer R, Moser D, Frass M, Oberbauer R, Kaye AD, Wagner O, Kapiotis S, Druml W: Effect of anticoagulation on blood membrane interactions during hemodialysis. Kidney Int 56: 1578-1583, 1999
25. Cicchetti T, Senatore RP, Frandina F, Ferrari S, Striano U, Milei M, Cosentino S: Dialysis treatment using an ethylene vinyl alcohol membrane and no anticoagulation for chronic uremic patients. Artif Organs 17: 816-819, 1993
26. Wiliner GD, Danitiz MP, Mudd MS, Hsiedh K-H, Fenton JW: Selective immobilization of thrombin by surface-bound fibrin. J Lab Clin Med 97: 403-411, 1980
27. Gosling J, Slaymaker S, Gu L, Tseng S, Zlot CH, Young SG, Rollins BJ, Charo IF: MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B. J Clin Invest 103: 773-780, 1999
28. Grooteman MP, Nube MJ, van Houte AJ, Schoorl M, van Limbeek J: Granulocyte sequestration in dialysers: A comparative elution study of three different membranes. Nephrol Dial Transplant 10: 1859-1864, 1995
29. Blomquist S, Malmros C, Martensson L, Thorne J: Absence of lung reactions after complement depletion during dialysis: An experimental study in pigs. Artif Organs 15: 397-401, 1991
30. Sester U, Sester M, Heine G, Kaul H, Girndt M, Kohler H: Strong depletion of CD14(+)CD16(+) monocytes during haemodialysis treatment. Nephrol Dial Transplant 16: 1402-1408, 2001
31. Franscini N, Bachli EB, Blau N, Leikauf MS, Schaffner A, Schoedon G: Gene expression profiling of inflamed human endothelial cells and influence of activated protein C. Circulation 110: 2903-2909, 2004
32. Brown Z, Gerritsen ME, Carley WW, Strieter RM, Kunkel SL, Westwick J: Chemokine gene expression and secretion by cytokine-activated human microvascular endothelial cells. Differential regulation of monocyte chemoattractant protein-1 and interleukin-8 in response to interferon-gamma. Am J Pathol 145: 913-921, 1994
33. Suzuki T, Kono H, Hirose N, Okada M, Yamamoto T, Yamamoto K, Honda Z: Differential involvement of Src family kinases in Fc gamma receptor-mediated phagocytosis. J Immunol 165: 473-482, 2000
34. Cannons JL, Schwartzberg PL: Fine-tuning lymphocyte regulation: What's new with tyrosine kinases and phosphatases? Curr Opin Immunol 16: 296-303, 2004
35. Zamoyska R, Basson A, Filby A, Legname G, Lovatt M, Seddon B: The influence of the src-family kinases, Lck and Fyn, on T cell differentiation, survival and activation. Immunol Rev 191: 107-118, 2003
36. Ernst M, Inglese M, Scholz GM, Harder KW, Clay FJ, Bozinovski S, Waring P, Darwiche R, Kay T, Sly P, Collins R, Turner D, Hibbs ML, Anderson GP, Dunn AR: Constitutive activation of the SRC family kinase Hck results in spontaneous pulmonary inflammation and an enhanced innate immune response. J Exp Med 196: 589-604, 2002
37. Tateno M, Nishida Y, Adachi-Yamada T: Regulation of JNK by Src during Drosophila development. Science 287: 324-327, 2000