-
1
-
-
0033452452
-
Proprotein and prohormone convertases: A family of subtilases generating diverse bioactive polypeptides
-
Seidah NG, Chretien M: Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides. Brain Res 1999, 848:45-62.
-
(1999)
Brain Res.
, vol.848
, pp. 45-62
-
-
Seidah, N.G.1
Chretien, M.2
-
2
-
-
0032991027
-
Expression of human prohormone convertase PC2 in a baculovirus-insect cell system
-
Fahnestock M, Zhu W: Expression of human prohormone convertase PC2 in a baculovirus-insect cell system. DNA Cell Biol 1999, 18:409-417.
-
(1999)
DNA Cell Biol.
, vol.18
, pp. 409-417
-
-
Fahnestock, M.1
Zhu, W.2
-
3
-
-
0029842866
-
Isolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes
-
Miranda L, Wolf J, Pichuantes S, Duke R, Franzusoff A: Isolation of the human PC6 gene encoding the putative host protease for HIV-1 gp160 processing in CD4+ T lymphocytes. Proc Natl Acad Sci U S A 1996, 93:7695-7700.
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 7695-7700
-
-
Miranda, L.1
Wolf, J.2
Pichuantes, S.3
Duke, R.4
Franzusoff, A.5
-
4
-
-
0028327614
-
Structure of the gene for the testis-specific proprotein convertase 4 and of its alternate messenger RNA isoforms
-
Mbikay M, Raffin-Sanson ML, Tadros H, Sirois F, Seidah NG, Chretien M: Structure of the gene for the testis-specific proprotein convertase 4 and of its alternate messenger RNA isoforms. Genomics 1994, 20:231-237.
-
(1994)
Genomics
, vol.20
, pp. 231-237
-
-
Mbikay, M.1
Raffin-Sanson, M.L.2
Tadros, H.3
Sirois, F.4
Seidah, N.G.5
Chretien, M.6
-
5
-
-
0025762119
-
PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues
-
Benjannet S, Rondeau N, Day R, Chretien M, Seidah NG: PC1 and PC2 are proprotein convertases capable of cleaving proopiomelanocortin at distinct pairs of basic residues. Proc Natl Acad Sci U S A 1991, 88:3564-3568.
-
(1991)
Proc. Natl. Acad. Sci. U. S,. A.
, vol.88
, pp. 3564-3568
-
-
Benjannet, S.1
Rondeau, N.2
Day, R.3
Chretien, M.4
Seidah, N.G.5
-
6
-
-
13044279492
-
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization
-
Seidah NG, Mowla SJ, Hamelin J, Mamarbachi AM, Benjannet S, Toure BB, Basak A, Munzer JS, Marcinkiewicz J, Zhong M, Barale JC, Lazure C, Murphy RA, Chretien M, Marcinkiewicz M: Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization. Proc Natl Acad Sci U S A 1999, 96:1321-1326.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 1321-1326
-
-
Seidah, N.G.1
Mowla, S.J.2
Hamelin, J.3
Mamarbachi, A.M.4
Benjannet, S.5
Toure, B.B.6
Basak, A.7
Munzer, J.S.8
Marcinkiewicz, J.9
Zhong, M.10
Barale, J.C.11
Lazure, C.12
Murphy, R.A.13
Chretien, M.14
Marcinkiewicz, M.15
-
7
-
-
0032764094
-
The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1
-
Seidah NG, Benjannet S, Hamelin J, Mamarbachi AM, Basak A, Marcinkiewicz J, Mbikay M, Chretien M, Marcinkiewicz M: The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1. Ann N Y Acad Sci 1999, 885:57-74.
-
(1999)
Ann. N. Y. Acad. Sci.
, vol.885
, pp. 57-74
-
-
Seidah, N.G.1
Benjannet, S.2
Hamelin, J.3
Mamarbachi, A.M.4
Basak, A.5
Marcinkiewicz, J.6
Mbikay, M.7
Chretien, M.8
Marcinkiewicz, M.9
-
8
-
-
0035878968
-
Neuroendocrine secretory protein 7B2: Structure, expression and functions
-
Mbikay M, Seidah NG, Chretien M: Neuroendocrine secretory protein 7B2: structure, expression and functions. Biochem J 2001, 357:329-342.
-
(2001)
Biochem. J.
, vol.357
, pp. 329-342
-
-
Mbikay, M.1
Seidah, N.G.2
Chretien, M.3
-
9
-
-
0033525771
-
The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease
-
Westphal CH, Muller L, Zhou A, Zhu X, Bonner-Weir S, Schambelan M, Steiner DF, Lindberg I, Leder P: The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease. Cell 1999, 96:689-700.
-
(1999)
Cell
, vol.96
, pp. 689-700
-
-
Westphal, C.H.1
Muller, L.2
Zhou, A.3
Zhu, X.4
Bonner-Weir, S.5
Schambelan, M.6
Steiner, D.F.7
Lindberg, I.8
Leder, P.9
-
10
-
-
0034640505
-
The SAAS granin exhibits structural and functional homology to 7B2 and contains a highly potent hexapeptide inhibitor of PC1
-
Cameron A, Fortenberry Y, Lindberg I: The SAAS granin exhibits structural and functional homology to 7B2 and contains a highly potent hexapeptide inhibitor of PC1. FEBS Lett 2000, 473:135-138.
-
(2000)
FEBS Lett.
, vol.473
, pp. 135-138
-
-
Cameron, A.1
Fortenberry, Y.2
Lindberg, I.3
-
11
-
-
0035722168
-
Human dermal fibroblasts express prohormone convertases 1 and 2 and produce proopiomelanocortin-derived peptides
-
Schiller M, Raghunath M, Kubitscheck U, Scholzen TE, Fisbeck T, Metze D, Luger TA, Bohm M: Human dermal fibroblasts express prohormone convertases 1 and 2 and produce proopiomelanocortin-derived peptides. J Invest Dermatol 2001, 117:227-235.
-
(2001)
J. Invest. Dermatol.
, vol.117
, pp. 227-235
-
-
Schiller, M.1
Raghunath, M.2
Kubitscheck, U.3
Scholzen, T.E.4
Fisbeck, T.5
Metze, D.6
Luger, T.A.7
Bohm, M.8
-
12
-
-
0028831096
-
Proprotein convertases (PC1/PC3 and PC2) in normal and neoplastic human tissues: Their use as markers of neuroendocrine differentiation
-
Scopsi L, Gullo M, Rilke F, Martin S, Steiner DF: Proprotein convertases (PC1/PC3 and PC2) in normal and neoplastic human tissues: their use as markers of neuroendocrine differentiation. J Clin Endocrinol Metab 1995, 80:294-301.
-
(1995)
J. Clin. Endocrinol. Metab.
, vol.80
, pp. 294-301
-
-
Scopsi, L.1
Gullo, M.2
Rilke, F.3
Martin, S.4
Steiner, D.F.5
-
13
-
-
0030822759
-
Immunohistochemical localization of the pro-peptide processing enzymes PC1/PC3 and PC2 in the human anal canal
-
Horsch D, Day R, Seidah NG, Weihe E, Schafer MK: Immunohistochemical localization of the pro-peptide processing enzymes PC1/PC3 and PC2 in the human anal canal. Peptides 1997, 18:755-760.
-
(1997)
Peptides
, vol.18
, pp. 755-760
-
-
Horsch, D.1
Day, R.2
Seidah, N.G.3
Weihe, E.4
Schafer, M.K.5
-
14
-
-
0035903230
-
Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: Importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions
-
Khatib AM, Siegfried G, Prat A, Luis J, Chretien M, Metrakos P, Seidah NG: Inhibition of proprotein convertases is associated with loss of growth and tumorigenicity of HT-29 human colon carcinoma cells: importance of insulin-like growth factor-1 (IGF-1) receptor processing in IGF-1-mediated functions. J Biol Chem 2001, 276:30686-30693.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30686-30693
-
-
Khatib, A.M.1
Siegfried, G.2
Prat, A.3
Luis, J.4
Chretien, M.5
Metrakos, P.6
Seidah, N.G.7
-
15
-
-
0034846315
-
Elevated furin expression in aggressive human head and neck tumors and tumor cell lines
-
Bassi DE, Mahloogi H, Al-Saleem L, Lopez De Cicco R, Ridge JA, Klein-Szanto AJ: Elevated furin expression in aggressive human head and neck tumors and tumor cell lines. Mol Carcinog 2001, 31:224-232.
-
(2001)
Mol. Carcinog.
, vol.31
, pp. 224-232
-
-
Bassi, D.E.1
Mahloogi, H.2
Al-Saleem, L.3
Lopez De Cicco, R.4
Ridge, J.A.5
Klein-Szanto, A.J.6
-
16
-
-
0035062810
-
Elevated expression of proprotein convertases alters breast cancer cell growth in response to estrogen and tamoxifen
-
Cheng M, Xu N, Iwasiow B, Seidah N, Chretien M, Shiu RP: Elevated expression of proprotein convertases alters breast cancer cell growth in response to estrogen and tamoxifen. J Mol Endocrinol 2001, 26:95-105.
-
(2001)
J. Mol. Endocrinol.
, vol.26
, pp. 95-105
-
-
Cheng, M.1
Xu, N.2
Iwasiow, B.3
Seidah, N.4
Chretien, M.5
Shiu, R.P.6
-
17
-
-
0026537585
-
Effect of LHRH on plasma 7B2 in patients with gonadotropin-producing pituitary adenomas
-
Iguchi H, Demura R, Yasuda D, Wakasugi H: Effect of LHRH on plasma 7B2 in patients with gonadotropin-producing pituitary adenomas. Horm Metab Res 1992, 24:31-33.
-
(1992)
Horm. Metab. Res.
, vol.24
, pp. 31-33
-
-
Iguchi, H.1
Demura, R.2
Yasuda, D.3
Wakasugi, H.4
-
18
-
-
0025949217
-
7B2, a possible marker for nonfunctioning pancreatic islet cell tumor
-
Iguchi H, Yasuda D, Yamada Y, Funakoshi A, Wakasugi H, Bloom SR, Chretien M: 7B2, a possible marker for nonfunctioning pancreatic islet cell tumor. Horm Metab Res 1991, 23:486-489.
-
(1991)
Horm. Metab. Res.
, vol.23
, pp. 486-489
-
-
Iguchi, H.1
Yasuda, D.2
Yamada, Y.3
Funakoshi, A.4
Wakasugi, H.5
Bloom, S.R.6
Chretien, M.7
-
19
-
-
0038481179
-
The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis
-
Siegfried G, Basak A, Cromlish JA, Benjannet S, Marcinkiewicz J, Chretien M, Seidah NG, Khatib AM: The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis. J Clin Invest 2003, 111:1723-1732.
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 1723-1732
-
-
Siegfried, G.1
Basak, A.2
Cromlish, J.A.3
Benjannet, S.4
Marcinkiewicz, J.5
Chretien, M.6
Seidah, N.G.7
Khatib, A.M.8
-
20
-
-
0037379743
-
The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity
-
Siegfried G, Khatib AM, Benjannet S, Chretien M, Seidah NG: The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity. Cancer Res 2003, 63:1458-1463.
-
(2003)
Cancer Res.
, vol.63
, pp. 1458-1463
-
-
Siegfried, G.1
Khatib, A.M.2
Benjannet, S.3
Chretien, M.4
Seidah, N.G.5
-
21
-
-
0029922634
-
Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin
-
Rovere C, Barbero P, Kitabgi P: Evidence that PC2 is the endogenous pro-neurotensin convertase in rMTC 6-23 cells and that PC1- and PC2-transfected PC12 cells differentially process pro-neurotensin. J Biol Chem 1996, 271:11368-11375.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 11368-11375
-
-
Rovere, C.1
Barbero, P.2
Kitabgi, P.3
-
22
-
-
0032961942
-
Neurotensin and a non-peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice
-
Maoret JJ, Anini Y, Rouyer-Fessard C, Gully D, Laburthe M: Neurotensin and a non-peptide neurotensin receptor antagonist control human colon cancer cell growth in cell culture and in cells xenografted into nude mice. Int J Cancer 1999, 80:448-454.
-
(1999)
Int. J. Cancer
, vol.80
, pp. 448-454
-
-
Maoret, J.J.1
Anini, Y.2
Rouyer-Fessard, C.3
Gully, D.4
Laburthe, M.5
-
23
-
-
0036679173
-
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects
-
Zhu X, Zhou A, Dey A, Norrbom C, Carroll R, Zhang C, Laurent V, Lindberg I, Ugleholdt R, Holst JJ, Steiner DF: Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects. Proc Natl Acad Sci U S A 2002, 99:10293-10298.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 10293-10298
-
-
Zhu, X.1
Zhou, A.2
Dey, A.3
Norrbom, C.4
Carroll, R.5
Zhang, C.6
Laurent, V.7
Lindberg, I.8
Ugleholdt, R.9
Holst, J.J.10
Steiner, D.F.11
-
24
-
-
0036678101
-
Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3
-
Zhu X, Orci L, Carroll R, Norrbom C, Ravazzola M, Steiner DF: Severe block in processing of proinsulin to insulin accompanied by elevation of des-64,65 proinsulin intermediates in islets of mice lacking prohormone convertase 1/3. Proc Natl Acad Sci U S A 2002, 99:10299-10304.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 10299-10304
-
-
Zhu, X.1
Orci, L.2
Carroll, R.3
Norrbom, C.4
Ravazzola, M.5
Steiner, D.F.6
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