3,4,3',4'-tetrachlorobiphenyl acts as an estrogen in vitro and in vivo

Molecular Endocrinology

Volumn 10, Issue 8, 1996, Pages 923-936

  Nesaretnam, K ^a   Corcoran, O ^a   Dils, R R ^a   Darbre, P ^a  

^a UNIVERSITY OF READING   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

3,3',4,4' TETRACHLOROBIPHENYL; ANTIESTROGEN; AROMATIC HYDROCARBON RECEPTOR; BETA NAPHTHOFLAVONE; CHLORAMPHENICOL ACETYLTRANSFERASE; CYTOCHROME P450; DEXAMETHASONE; DIETHYLSTILBESTROL; DNA; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; FULVESTRANT; MESSENGER RNA; N BUTYL 11 (3,17BETA DIHYDROXYESTRA 1,3,5(10) TRIEN 7ALPHA YL) N METHYLUNDECANAMIDE; TAMOXIFEN; TETRACHLOROBIPHENYL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER CELL; CELL GROWTH; CONTROLLED STUDY; DNA SYNTHESIS; DOSE RESPONSE; FEMALE; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; LIGAND BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; TOPICAL DRUG ADMINISTRATION; UTERUS WEIGHT;

ANIMALS; BINDING, COMPETITIVE; BREAST NEOPLASMS; CELL DIVISION; CHLORAMPHENICOL O-ACETYLTRANSFERASE; DNA; ENVIRONMENTAL POLLUTANTS; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MICE; ORGAN SIZE; POLYCHLORINATED BIPHENYLS; RECEPTORS, ESTROGEN; TRANSFECTION; TUMOR CELLS, CULTURED; UTERUS;

ANIMALIA;

EID: 0029758425     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.10.8.923     Document Type: Article

References (79)

1. Hunter DJ, Kelsey KT 1993 Pesticide residues and breast cancer: the harvest of a silent spring. J Natl Cancer Inst 85:598-599
2. Colborn T, Vom Saal FS, Soto AM 1993 Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environ Health Perspect 101:378-384
3. Rennie J 1993 Malignant mimicry. Sci Am 269:15-16
4. Sharpe RM, Skakkebaek NF 1993 Are estrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet 341:1392-1395
5. Sumpter JP, Jobling S 1993 Male sexual development in "a sea of oestrogen". Lancet 342:124-125
6. Davis DL, Bradlow HL, Wolff M, Woodruff T, Hoel DG, Anton-Culver H 1993 Medical hypothesis: xenoestrogens as preventable causes of breast cancer. Environ Health Perspect 101:372-377
7. Stone R 1994 Environmental estrogens stir debate. Science 265:308-310
8. Safe SH 1994 Dietary and environmental estrogens and antiestrogens and their possible role in human disease. Environ Sci Pollut Res 1:29-33
9. Fagin D 1994 Estrogen link. Newsday (28 Dec), pp A7-A9
10. Safe SH 1995 Environmental and dietary estrogens and human health: is there a problem? Environ Health Perspect 103:346-351
11. Guillette LJ, Gross TS, Masson GR, Matter JM, Percival HF, Woodward AR 1994 Developmental abnormalities of the gonad and abnormal sex hormone concentrations in juvenile alligators from contaminated and control lakes in Florida. Environ Health Perspect 102:680-688
12. Colborn T 1991 Epidemiology of Great Lake bald eagles. J Toxicol Environ Health 33:395-453
13. Dirksen S, Boudewijn TJ, Slager LK, Mes RG, van Schaick MJM, de Voogt P 1995 Reduced breeding success of cormorants (Phalacrocorax carbo sinensis) in relation to persistent organochlorine pollution of aquatic habitats in the Netherlands. Environ Pollut 88:119-132
14. Purdom CE, Hardiman PA, Bye VJ, Eno NC, Tyler CR, Sumpter JP 1994 Estrogenic effects of effluents from sewage treatment works. Chem Ecol 8:275-285
15. White R, Jobling S, Hoare SA, Sumpter JP, Parker MG 1994 Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology 135:175-182
16. Falck F, Ricci A, Wolff MS, Godbold J, Deckers P 1992 Pesticides and polychlorinated biphenyl residues in human breast lipids and their relation to breast cancer. Arch Environ Health 47:143-146
17. Wolff MS, Toniolo PG, Leel EW, Rivera M, Dubin N 1993 Blood levels of organochlorine residues and risk of breast cancer. J Natl Cancer Inst 85:648-652
18. Dewailly E, Dodin S, Verreault R, Ayotte P, Sauve L, Morin J, Brisson J 1994 High organochlorine body burden in women with estrogen receptor-positive breast cancer. J Natl Cancer Inst 86:232-234
19. Krieger N, Wolff MS, Hiatt RA, Rivera M, Vogelman J, Orentreich N 1994 Breast cancer and serum organochlorines: a prospective study among white, black and Asian women. J Natl Cancer Inst 86:589-599
20. Key T, Reeves G 1994 Organochlorines in the environment and breast cancer. Br Med J 308:1520-1521
21. Berthois Y, Katzenellenbogen JA, Katzenellenbogen BS 1986 Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture. Proc Natl Acad Sci USA 83:2496-2500
22. Bindal RD, Katzenellenbogen JA 1988 Bis-(4-hydroxyphenyl-(2-(phenoxysulfonyl)phenyl)methane: isolation and structural elucidation of a novel estrogen from commercial preparations of phenol red (phenolsulfonphthalein). J Med Chem 31:1978-1983
23. Soto AM, Justica H, Wray JW, Sonnenschein C 1991 Nonyl-phenol: an estrogenic xenobiotic released from "modified" polystyrene. Environ Health Perspect 92:167-173
24. Krishnan AV, Stathis P, Permuth SF, Tokes L, Feldman D 1993 Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclaving. Endocrinology 132:2279-2286
25. Soto AM, Chung KL, Sonnenschein C 1994 The pesticides endosulfan, toxaphene and dieldrin have estrogenic effects on human estrogen-sensitive cells. Environ Health Perspect 102:380-383
26. Jobling S, Reynolds T, White R, Parker MG, Sumpter J 1995 A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Environ Health Perspect 103:582-587
27. Borlakoglu J, Dils R 1990 Polychlorinated biphenyls (PCBs) and marine food chains. Biologist 37:145-147
28. Loganathan BG, Kannan K 1994 Global organochlorine contamination trends: an overview. Ambio 23:187-191
29. Dobson S, van Esch GJ 1993 Polychlorinated Biphenyls and Terphenyls, ed 2. Environmental Health Criteria 140. World Health Organization, Geneva, Switzerland
30. Safe S 1994 Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. CRC Crit Rev Toxicol 24:87-149
31. Borlakoglu JT, Oils RR 1991 PCBs in human tissues. Chemistry in Britain (Sept 1991), pp 814-818
32. Landers JP, Bunce NJ 1991 The Ah receptor and the mechanism of dioxin toxicity. Biochem J 276:273-287
33. Brouwer A 1991 The role of enzymes in regulating the toxicity of xenobiotics. Biochem Soc Trans 19:731-737
34. Korach KS, Sarver P, Chae K, McLachlan JA, McKinney JD 1988 Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes. Mol Pharmacol 33:120-126
35. Ecobichon DJ, MacKenzie DO 1974 The uterotropic activity of commercial and isomerically-pure chlorobiphenyls in the rat. Res Commun Chem Pathol Pharmacol 9:85-94
36. Gellert RJ 1978 Uterotrophic activity of polychlorinated biphenyls (PCB) and induction of precocious reproductive aging in neonatally treated female rats. Environ Res 16:123-130
37. Jansen HT, Cooke PS, Porcelli J, Liu TC, Hansen LG 1993 Estrogenic and antiestrogenic actions of PCBs in the female rat: in vitro and in vivo studies. Reprod Toxicol 7:237-248
38. Fuller GB, Hobson WC 1986 Effect of PCBs on reproduction in mammals. In: Waid JS (ed) PCBs and the Environment. CRC Press, Boca Raton, FL, pp 101-125
39. Birnbaum LS 1994 Endocrine effects of prenatal exposure to PCBs, dioxins and other xenobiotics: implications for policy and future research. Environ Health Perspect 102:676-679
40. McKinney JD, Waller CL 1994 Polychlorinated biphenyls as hormonally active structural analogues. Environ Health Perspect 102:290-297
41. Parker MG (ed) 1991 Nuclear Hormone Receptors: Molecular Mechanisms, Cellular Functions, Clinical Abnormalities. Academic Press, London
42. Metzger, D, Berry, M, Ali, S, Chambon, P 1995 Effect of antagonists on DNA binding properties of the human estrogen receptor in vitro and in vivo. Mol Endocrinol 9:579-591
43. Masiakowski P, Breathnach R, Bloch J, Gannon F, Krust A, Chambon P 1982 Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res 10:7895-7903
44. Glover JF, Irwin JT, Darbre PD 1988 Interaction of phenol red with estrogenic and antiestrogenic action on growth of human breast cancer cells ZR-75-1 and T-47-D. Cancer Res 48:3693-3697
45. Darbre PD, Daly RJ 1989 Effects of oestrogen on human breast cancer cells in culture. Proc R Soc Edin 95B:119-132
46. Harris M, Piskorska-Pliszczynska J, Zacharewski T, Romkes M, Safe S 1989 Structure-dependent induction of aryl hydrocarbon hydroxylase in human breast cancer cell lines and characterisation of the Ah receptor. Cancer Res 49:4531-4535
47. Lu YF, Santostefano M, Cunningham BDM, Threadgill MD, Safe,S 1995 Identification of 3′-methoxy-4′-nitroflavone as a pure aryl hydrocarbon (Ah) receptor antagonist and evidence for more than one form of the nuclear Ah receptor in MCF-7 human breast cancer cells. Arch Biochem Biophys 316:470-477
48. Farin, FM, Pohlman TH, Omiecinski CJ 1994 Expression of cytochrome P450s and microsomal epoxide hydroxylase in primary cultures of human umbilical vein endothelial cells. Toxicol Appl Pharmacol 124:1-9
49. Fujisawa-Sehara A, Sogawa K, Yamane M, Fujii-Kuriyama Y 1987 Characterisation of xenobiotic responsive elements upstream from the drug-metabolising cytochrome P-450c gene: a similarity to glucocorticoid regulatory element. Nucleic Acids Res 15:4179-4191
50. Fujisawa-Sehara A, Sogawa K, Yamane M, Fujii-Kuriyama Y 1988 A DMA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to the nucleus. Proc Natl Acad Sci USA 85:5859-5863
51. Hapgood J, Cuthill S, Denis M, Poellinger L, Gustafsson J-A 1989 Specific protein-DNA interactions at a xenobiotic responsive element: copurification of dioxin receptor and DNA-binding activity. Proc Natl Acad Sci USA 86:60-64
52. Arellano LO, Wang X, Safe S 1993 Effects of cycloheximide on the induction of CYPIA1 gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in three human breast cancer cell lines. Carcinogenesis 14:219-222
53. Wakeling AE 1992 Steroid antagonists as nuclear receptor blockers. Cancer Surv 14:71-85
54. Wakeling AE 1993 The future of new pure antiestrogens in clinical breast cancer. Breast Cancer Res Treat 25:1-9
55. Safe S, Krishnan V 1995 Cellular and molecular biology of aryl hydrocarbon (Ah) receptor-mediated gene expression. Arch Toxicol Suppl 17:99-115
56. Daly RJ, King RJB, Darbre PD 1990 Interaction of growth factors during progression towards steroid independence in T-47-D human breast cancer cells. J Cell Biochem 43:199-211
57. Webb P, Lopez GN, Uht RM, Kushner PJ 1995 Tamoxifen activation of the estrogen receptor/AP-1 pathway: potential origin for the cell-specific estrogen-like effects of antiestrogens. Mol Endocrinol 9:443-456
58. Umayahara Y, Kawamori R, Watada H, Imano E, Iwama N, Morishima T, Yamasaki Y, Kajimoto Y, Kamada T 1994 Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer. J Biol Chem 269:16433-16442
59. Philips A, Chalbos D, Rochefort H 1993 Estradiol increases and ant-estrogens antagonize the growth factor-induced activator protein-1 activity in MCF7 breast cancer cells without affecting c-fos and c-jun synthesis. J Biol Chem 268:14103-14108
60. Gaub MP, Bellard M, Scheuer I, Chambon P, Sassone CP 1990 Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex. Cell 63:1267-1276
61. Timbrell JA 1992 Principles of Biochemical Toxicology. Taylor and Francis Ltd., London
62. Darbre PD, Curtis S, King RJB 1984 Effects of estradiol and tamoxifen on human breast cancer cells in serum-free culture. Cancer Res 44:2790-2793
63. Reddel RR, Sutherland RL 1984 Tamoxifen stimulation of human breast cancer cell proliferation in vitro: a possible model for tamoxifen tumour flare. Eur J Cancer Clin Oncol 20:1419-1424
64. Beck JS (ed.) 1989 Oestrogen and the Human Breast. Proc R Soc Edin 95B:1-311
65. Lipworth L 1995 Epidemiology of breast cancer. Eur J Cancer Prevention 4:7-30
66. Miller WR 1990 General review: endocrine therapy for breast cancers: biological rationale and current progress. J Steroid Biochem Mol Biol 37:467-480
67. Chlebowski RT, Rose D, Buzzard IM, Blackburn GL, Insull W, Grosvenor M, Elashoff R, Wynder EL 1991 Adjuvant dietary fat intake reduction in postmenopausal breast cancer patient management. Breast Cancer Res Treat 20:73-84
68. Darbre P, Yates J, Curtis S, King RJB 1983 Effect of estradiol on human breast cancer cells in culture. Cancer Res 43:349-354
69. Osborne CK, Hobbs K, Trent JM 1987 Biological differences among MCF-7 human breast cancer cell lines from different laboratories. Breast Cancer Res Treat 9:111-121
70. Engel LW, Young NA, Tralka TS, Lippman ME, O'Brien SJ, Joyce MJ 1978 Establishment and characterisation of three new continuous cell lines derived from human breast carcinomas. Cancer Res 38:3352-3364
71. Keydar I, Chen L, Karby S, Weiss FR, Delarea J, Radu M, Chaitcik S, Brenner HJ 1979 Establishment and characterisation of a cell line of human breast carcinoma origin. Eur J Cancer 15:659-670
72. Green B, Leake RE 1987 Steroid Hormones: A Practical Approach. IRL Press Ltd., Oxford, U.K.
73. White R, Parker M 1993 Analysis of cloned factors. In: Latchman DS (ed) Transcription Factors: A Practical Approach. IRL Press, Oxford, U.K., pp 143-179
74. Wigler M, Pellicer A, Silverstein S, Axel R, Urlaub G, Chasin L 1979 DNA mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells. Proc Natl Acad Sci USA 76:1373-1376
75. Sleigh MJ 1986 A nonchromatographic assay for expression of the chloramphenicol acetyltransferase gene in eucaryotic cells. Anal Biochem 156:251-256
76. Maniatis T, Fitsch EF, Sambrook J 1982 Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
77. Daly RJ, Darbre PD 1990 Cellular and molecular events in loss of estrogen sensitivity in ZR-75-1 and T-47-D human breast cancer cells. Cancer Res 50:5868-5875
78. Brown AMC, Jeltsch JM, Roberts M, Chambon P 1984 Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc Natl Acad Sci USA 81:6344-6348
79. Darbre P, King RJB 1984 Progression to steroid autonomy in S115 mouse mammary tumor cells: role of DNA methylation. J Cell Biol 99:1410-1415