BARHL1 homeogene, the human ortholog of the mouse Barhl1 involved in cerebellum development, shows regional and cellular specificities in restricted domains of developing human central nervous system

Biochemical and Biophysical Research Communications

Volumn 339, Issue 1, 2006, Pages 296-304

  Lopes, Carmela ^a,c   Delezoide, Anne Lise ^b   Delabar, Jean Maurice ^a   Rachidi, Mohammed ^a  

^a EA 3508 Université Paris   (France)

^b HÔPITAL ROBERT DEBRÉ   (France)

^c UNIVERSITÉ DE LA POLYNÉSIE FRANÇAISE   (French Polynesia)

Author keywords

BARHL1 homeobox gene; BMP signaling pathway; Cell differentiation; Cerebellar granular cells; Cerebellar pathology; dl1 dorsal sensory neurons; Joubert syndrome; Lhx2; Math1; Prosomeres p1 p4

Indexed keywords

BONE MORPHOGENETIC PROTEIN; HOMEOBOX PROTEIN BARHL 1; HOMEODOMAIN PROTEIN; MESSENGER RNA; PROLINE; SERINE; THREONINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MATH 1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN REGION; BRIGHT FIELD MICROSCOPY; CARBOXY TERMINAL SEQUENCE; CELL DIFFERENTIATION; CELL MIGRATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DIENCEPHALON; DROSOPHILA; EMBRYO; EMBRYONIC STEM CELL; GENE FUNCTION; GENETIC CONSERVATION; GRANULAR CELL; HOMEOBOX; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN ISOLATION; PROTEIN STRUCTURE; RHOMBENCEPHALON; SENSORY NERVE; SEQUENCE HOMOLOGY; SPECIES COMPARISON; STRUCTURAL HOMOLOGY; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CEREBELLUM; HOMEODOMAIN PROTEINS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; DANIO RERIO;

EID: 28144455158     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.11.021     Document Type: Article

References (62)

1. M.E. Hallonet, and N.M. Le Douarin Tracing neuroepithelial cells of the mesencephalic and metencephalic alar plates during cerebellar ontogeny in quail-chick chimaeras Eur. J. Neurosci. 5 1993 1145 1155
2. R.J. Wingate, and M.E. Hatten The role of the rhombic lip in avian cerebellum development Development 126 1999 4395 4404
3. S. Millet, E. Bloch-Gallego, A. Simeone, and R.M. Alvarado-Mallart The caudal limit of Otx2 gene expression as a marker of the midbrain/hindbrain boundary: a study using in situ hybridisation and chick/quail homotopic grafts Development 122 1996 3785 3797
4. R.J. Wingate The rhombic lip and early cerebellar development Curr. Opin. Neurobiol. 11 2001 82 88
5. S. Li, F. Qiu, A. Xu, S.M. Price, and M. Xiang Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene J. Neurosci. 24 2004 3104 3114
6. S. Higashijima, T. Kojima, T. Michiue, S. Ishimaru, Y. Emori, and K. Saigo Dual Bar homeo box genes of Drosophila required in two photoreceptor cells, R1 and R6, and primary pigment cells for normal eye development Genes Dev. 6 1992 50 60
7. S. Higashijima, T. Michiue, Y. Emori, and K. Saigo Subtype determination of Drosophila embryonic external sensory organs by redundant homeo box genes BarH1 and BarH2 Genes Dev. 6 1992 1005 1018
8. M. Sato, T. Kojima, T. Michiue, and K. Saigo Bar homeobox genes are latitudinal prepattern genes in the developing Drosophila notum whose expression is regulated by the concerted functions of decapentaplegic and wingless Development 126 1999 1457 1466
9. J. Lim, and K.W. Choi Induction and autoregulation of the anti-proneural gene Bar during retinal neurogenesis in Drosophila Development 131 2004 5573 5580
10. J.I. Pueyo, and J.P. Couso Chip-mediated partnerships of the homeodomain proteins Bar and Aristaless with the LIM-HOM proteins Apterous and LIM1 regulate distal leg development Development 131 2004 3107 3120
11. J.I. Pueyo, M.I. Galindo, S.A. Bishop, and J.P. Couso Proximal-distal leg development in Drosophila requires the apterous gene and Lim1 homologue dlim1 Development 127 2000 5391 5402
12. D.E. Rincon-Limas, C.H. Lu, I. Canal, M. Calleja, C. Rodríguez- Esteban, J.C. Izpisúa-Belmonte, and J. Botas Conservation of the expression and function of apterous orthologs in Drosophila and mammals Proc. Natl. Acad. Sci. USA 96 1999 2165 2170
13. C.H. Lu, D.E. Rincon-Limas, and J. Botas Conserved overlapping and reciprocal expression of msh/Msx1 and apterous/Lhx2 in Drosophila and mice Mech. Dev. 99 2000 177 181
14. A.J. Barlow, J.P. Bogardi, R. Ladher, and P.H. Francis-West Expression of chick Barx-1 and its differential regulation by FGF-8 and BMP signaling in the maxillary primordia Dev. Dyn. 214 1999 291 302
15. R. Ladher, T.J. Mohun, J.C. Smith, and A.M. Snape Xom: a Xenopus homeobox gene that mediates the early effects of BMP-4 Development 122 1996 2385 2394
16. D. Onichtchouk, V. Gawantka, R. Dosch, H. Delius, K. Hirschfeld, C. Blumenstock, and C. Niehrs The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling dorsoventral patterning of Xenopus mesoderm Development 122 1996 3045 3053
17. N. Martynova, F. Eroshkin, G. Ermakova, A. Bayramov, J. Gray, R. Grainger, and A. Zaraisky Patterning the forebrain: FoxA4a/Pintallavis and Xvent2 determine the posterior limit of Xanf1 expression in the neural plate Development 131 2004 2329 2338
18. S. Rastegar, H. Friedle, G. Frommer, and W. Knöchl Transcriptional regulation of Xvent homeobox genes Mech. Dev. 81 1999 136 149
19. M. Rachidi, C. Lopes, S. Gassanova, P.M. Sinet, M. Vekemans, T. Attie, A.L. Delezoide, and J.M. Delabar Regional and cellular specificity of the expression of TPRD, the tetratricopeptide Down syndrome gene, during human embryonic development Mech. Dev. 93 2000 189 193
20. R. O'Rahilly, and F. Müller Developmental Stages in Human Embryos 1987 Carnagie Institution of Washington Washington
21. T. Saito, K. Sawamoto, H. Okano, D.J. Anderson, and K. Mikoshiba Mammalian BarH homologue is a potential regulator of neural bHLH genes Dev. Biol. 199 1998 216 225
22. L. Puelles, and J.L. Rubenstein Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization Trends Neurosci. 16 1993 472 479
23. J.L. Rubenstein, S. Martinez, K. Shimamura, and L. Puelles The embryonic vertebrate forebrain: the prosomeric model Science 266 1994 578 580
24. L. Puelles A segmental morphological paradigm for understanding vertebrate forebrains Brain Behav. Evol. 46 1995 319 337
25. M. Rachidi, C. Lopes, G. Charron, A.L. Delezoide, E. Paly, B. Bloch, and J.M. Delabar Spatial and temporal localization during embryonic and fetal human development of the transcription factor SIM2 in brain regions altered in Down syndrome Int. J. Dev. Neurosci. 23 2005 475 484
26. D. Duboule Guidebook to the Homeobox Genes 1994 Oxford University Press Oxford pp. 28-71
27. M.A. Kennedy, R. Gozalez-Sarmiento, U.R. Kees, F. Lampert, T.M. Dear, T. Boehm, and T.H. Rabbitts Hox 11, a homeobox-containing T cell oncogene found on human chromosome 10q24 Proc. Natl. Acad. Sci. USA 88 1991 8900 8904
28. T.N. Dear, I. Sanchez-Garcia, and T.H. Rabbitts The Hox 11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes Proc. Natl. Acad. Sci. USA 90 1993 4431 4435
29. K. Jagla, I. Stanceva, G. Dretzen, F. Bellard, and M. Bellard A distinct class of homeodomain proteins is encoded by two sequentially expressed Drosophila genes from 93D/E cluster Nucleic Acids Res. 22 1994 1202 1207
30. J. Ma, and M. Ptashne Deletion analysis of GAL4 defines two transcriptional activating segments Cell 48 1987 847 853
31. N. Mermod, E.A. O'Neill, T.J. Kelley, and R. Tjian The praline rich transcriptional activator of CTF/NF-1 is distinct from the replication and DNA binding domain Cell 58 1989 741 753
32. W. Hanna-Rose, and U. Hansen Active repression mechanisms of eukaryotic transcription repressors Trends Genet. 12 1996 229 234
33. A. Bulfone, E. Menguzzato, V. Broccoli, A. Marchitiello, C. Gattuso, M. Mariani, G.G. Consalez, S. Martinez, A. Ballabio, and S. Banfi Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS Hum. Mol. Genet. 9 2000 1443 1452
34. Y. Tanabe, and T.M. Jessell Diversity and pattern in the developing spinal cord Science 274 1996 1115 1123
35. P.G. Gillespie, and R.G. Walker Molecular basis of mechanosensory transduction Nature 413 2001 194 202
36. D. Julius, and A.I. Basbaum Molecular mechanisms of nocireception Nature 413 2001 203 210
37. K.J. Lee, and T.M. Jessell The specification of dorsal cell fates in the vertebrate central nervous system Annu. Rev. Neurosci. 22 1999 261 294
38. K. Gowan, A.W. Helms, T.L. Hunsaker, T. Collisson, P.J. Ebert, R. Odom, and J.E. Johnson Crossinhibitory activities of Ngn1 and Math1 allow specification of distinct dorsal interneurons Neuron 31 2001 219 232
39. T. Muller, H. Brohmann, A. Pierani, P.A. Heppenstall, G.R. Lewin, T.M. Jessell, and C. Birchmeier The homeodomain factor lbx1 distinguishes two major programs of neuronal differentiation in the dorsal spinal cord Neuron 34 2002 551 562
40. F. Müller, and R. O'Rahilly The development of the human brain, the closure of the caudal neuropore, and the beginning of secondary neurulation at stage 12 Anat. Embryol. 176 1987 413 430
41. C.I. Rodriguez, and S.M. Dymecki Origin of the precerebellar system Neuron 27 2000 475 486
42. N. Papalopulu, and C. Kintner A Xenopus gene, Xbr-1, defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye Dev. Biol. 174 1996 104 114
43. J.E. Schmidt, G. von Dassow, and D. Kimelman Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox Development 122 1996 1711 1721
44. A. Schuler-Metz, S. Knochel, E. Kaufmann, and W. Knochel The homeodomain transcription factor Xvent-2 mediates autocatalytic regulation of BMP-4 expression in Xenopus embryos J. Biol. Chem. 275 2000 34365 34374
45. N.J. Messenger, C. Kabitschke, R. Andrews, D. Grimmer, R. Nunez Miguel, T.L. Blundell, J.C. Smith, and F.C. Wardle Functional specificity of the Xenopus T-domain protein Brachyury is conferred by its ability to interact with Smad1 Dev. Cell 8 2005 599 610
46. R.W. Padgett, R.D. St Johnston, and W.M. Gelbart A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-beta family Nature 325 1987 81 84
47. J. Jordan, M. Bottner, H.J. Schluesener, K. Unsicker, and K. Krieglstein Bone morphogenetic proteins: neurotrophic roles for midbrain dopaminergic neurons and implications of astroglial cells Eur. J. Neurosci. 9 1997 1699 1709
48. J. Alder, K.J. Lee, T.M. Jessell, and M.E. Hatten Generation of cerebellar granule neurons in vivo by transplantation of BMP-treated neural progenitor cells Nat. Neurosci. 2 1999 535 540
49. I. Rios, R. Alvarez-Rodriguez, E. Marti, and S. Pons Bmp2 antagonizes sonic hedgehog-mediated proliferation of cerebellar granule neurones through Smad5 signalling Development 131 2004 3159 3168
50. N.A. Bermingham, B.A. Hassan, S.D. Price, M.A. Vollrath, N. Ben-Arie, R.A. Eatock, H.J. Bellen, A. Lysakowski, and H.Y. Zoghbi Math1: an essential gene for the generation of inner ear hair cells Science 284 1999 1837 1841
51. N. Ben-Arie, H.J. Bellen, D.L. Armstrong, A.E. McCall, P.R. Gordadze, Q. Guo, M.M. Matzuk, and H.Y. Zoghbi Math1 is essential for genesis of cerebellar granule neurons Nature 390 1997 169 172
52. S. Li, S.M. Price, H. Cahill, D.K. Ryugo, M.M. Shen, and M. Xiang Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene Development 129 2002 3523 3532
53. A. Chalazonitis, F. D'Autreaux, U. Guha, T.D. Pham, C. Faure, J.J. Chen, D. Roman, L. Kan, T.P. Rothman, J.A. Kessler, and M.D. Gershon Bone morphogenetic protein-2 and -4 limit the number of enteric neurons but promote development of a TrkC-expressing neurotrophin-3-dependent subset J. Neurosci. 24 2004 4266 4282
54. E. Gratacos, N. Checa, E. Perez-Navarro, and J. Alberch Brain-derived neurotrophic factor (BDNF) mediates bone morphogenetic protein-2 (BMP-2) effects on cultured striatal neurones J. Neurochem. 79 2001 747 755
55. W.A. Gomes, and J.A. Kessler Msx-2 and p21 mediate the pro-apoptotic but not the anti-proliferative effects of BMP4 on cultured sympathetic neuroblasts Dev. Biol. 237 2001 212 221
56. Q. Song, M. Mehler, and J.A. Kessler Bone morphogenetic proteins induce apoptosis and growth factor dependence of cultured sympathoadrenal progenitor cells Dev. Biol. 196 1998 119 127
57. S. Althini, D. Usoskin, A. Kylberg, P.L. Kaplan, and T. Ebendal Blocked MAP kinase activity selectively enhances neurotrophic growth responses Mol. Cell. Neurosci. 25 2004 345 354
58. K. Saar, L. Al-Gazali, L. Sztriha, F. Rueschendorf, E.K.M. Nur, A. Reis, and R. Bayoumi Homozygosity mapping in families with Joubert syndrome identifies a locus on chromosome 9q34.3 and evidence for genetic heterogeneity Am. J. Hum. Genet. 65 1999 1666 1671
59. M. Joubert, J.J. Eisenring, J.P. Robb, and F. Andermann Familial agenesis of the cerebellar vermis. A syndrome of episodic hyperpnea, abnormal eye movements, ataxia, and retardation Neurology 19 1969 813 825
60. J.M. Saraiva, and M. Baraitser Joubert syndrome: a review Am. J. Med. Genet. 43 1992 726 731
61. I.P. Blair, R.R. Gibson, C.L. Bennett, and P.F. Chance Search for genes involved in Joubert syndrome: evidence that one or more major loci are yet to be identified and exclusion of candidate genes EN1, EN2, FGF8, and BARHL1 Am. J. Med. Genet. 107 2002 190 196
62. D.B. Gould, and M.A. Walter Mutational analysis of BARHL1 and BARX1 in three new patients with Joubert syndrome Am. J. Med. Genet. 131A 2004 205 208