Active site driven ligand design: An evolution approach

Journal of Bioinformatics and Computational Biology

Volumn 3, Issue 5, 2005, Pages 1053-1070

  Bandyopadhyay, Sanghamitra ^a   Bagchi, Angshuman ^b   Maulik, Ujjwal ^c  

^a INDIAN STATISTICAL INSTITUTE   (India)

^b BOSE INSTITUTE   (India)

^c JADAVPUR UNIVERSITY   (India)

Author keywords

Active site; Ligand Docking; Target protein receptor; Tree structured representation; Variable string length genetic algorithm

Indexed keywords

LIGAND;

ARTICLE; CHROMOSOME SIZE; COMPUTER AIDED DESIGN; COMPUTER PROGRAM; DRUG BINDING SITE; DRUG DESIGN; DRUG PROTEIN BINDING; ENERGY BALANCE; GENETIC ALGORITHM; GEOMETRY; LIGAND BINDING; MATHEMATICAL COMPUTING; MOLECULAR EVOLUTION; MOLECULAR SIZE; MUTATIONAL ANALYSIS; PHARMACOPHORE; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN DATABASE; PROTEIN STRUCTURE; PROTEIN TARGETING;

BINDING SITES; DRUG DELIVERY SYSTEMS; DRUG DESIGN; LIGANDS; PHARMACEUTICAL PREPARATIONS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEINS; SEQUENCE ANALYSIS, PROTEIN;

EID: 28044464697     PISSN: 02197200     EISSN: None     Source Type: Journal    
DOI: 10.1142/S021972000500148X     Document Type: Article

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