Variational calculus (optimal control) applied to the optimization of the enzymatic synthesis of ampicillin

Brazilian Archives of Biology and Technology

Volumn 48, Issue SPEC. ISS., 2005, Pages 19-28

  De Arruda Ribeiro, Marcelo Perencin ^a   Giordano, Roberto De Campos ^a  

^a FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

Author keywords

Fed batch reactor optimization; Optimal control; Synthesis of lactam antibiotics

Indexed keywords

EID: 27944505942     PISSN: 15168913     EISSN: 15168913     Source Type: Journal    
DOI: 10.1590/s1516-89132005000400003     Document Type: Article

References (8)

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5. Ramirez, W. F. (1994), Process control and identification. San Diego : Academic Press Inc.
6. Srinivasan, B.; Palanki, S. and Bonvin, D. (2003), Dynamic optimization of batch processes. I. Characterization of the nominal solution. Computers and Chemical Eng., 27, 1-26.
7. Vieira, M. F. (2003), Separação de ampicilina obtida par síntese enzimática cineticamente controlada. PhD Thesis, Universidade Federal de São Carlos, São Carlos, Brazil.
8. Youshko, M. I.; Langen, L. M.; Vroom, E.; Rantwijk, F.; Sheldon, R. A. and Svedas, V. K. (2001), Highly efficient synthesis of ampicillin in "aqueous solution-precipitate" systems: repetitive addition of substrates in a semicontinuous process. Biotechnology And Bioengineering, 73, 426-430.