Synthesis, structure and biological activity of a new and efficient Cd(II)-uracil derivative complex system for cleavage of DNA

Journal of Biological Inorganic Chemistry

Volumn 10, Issue 8, 2005, Pages 924-934

  Illán Cabeza, Nuria A ^a   Vilaplana, Rosario A ^b   Alvarez, Ysmael ^c   Akdi, Khalid ^b   Kamah, Sanae ^b   Hueso Ureña, Francisco ^a   Quirós, Miguel ^d   González Vílchez, Francisco ^b   Moreno Carretero, Miguel N ^a  

^a UNIVERSITY OF JAÉN   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^d UNIVERSITY OF GRANADA   (Spain)

Author keywords

Antitumor; Cadmium complexes; Cytotoxicity; DNA; Schiff bases

Indexed keywords

2,6 BIS[1 (4 AMINO 1,2,3,6 TETRAHYDRO 1,3 DIMETHYL 2,6 DIOXOPYRIMIDIN 5 YL)IMINO]ETHYLPYRIDINE CADMIUM COMPLEX; ANTINEOPLASTIC AGENT; CADMIUM DERIVATIVE; DNA; NITROGEN; NUCLEIC ACID; PLASMID DNA; SCHIFF BASE; UNCLASSIFIED DRUG; URACIL DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CANCER CELL CULTURE; CELL DEGENERATION; CIRCULAR DICHROISM; CYTOTOXICITY; DNA BINDING; DNA CLEAVAGE; DNA HELIX; DRUG STRUCTURE; DRUG SYNTHESIS; ELECTROPHORESIS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DENATURATION; X RAY DIFFRACTION;

ANIMALS; ANTINEOPLASTIC AGENTS; CADMIUM; CATTLE; CELL PROLIFERATION; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; DNA; DNA DAMAGE; ELECTROPHORESIS; HUMANS; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PLASMIDS; TUMOR CELLS, CULTURED; URACIL;

EID: 27944479990     PISSN: 09498257     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00775-005-0045-x     Document Type: Article

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