-
1
-
-
0028133013
-
NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA
-
Denny BJ, Wheelhouse RT, Stevens MF, et al. NMR and molecular modeling investigation of the mechanism of activation of the antitumor drug temozolomide and its interaction with DNA. Biochemistry. 1994;33:9045-9051.
-
(1994)
Biochemistry
, vol.33
, pp. 9045-9051
-
-
Denny, B.J.1
Wheelhouse, R.T.2
Stevens, M.F.3
-
2
-
-
0026513077
-
Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856)
-
Newlands ES, Blackledge GR, Slack JA, et al. Phase I trial of temozolomide (CCRG 81045: M&B 39831: NSC 362856). Br J Cancer. 1992;65:287-291.
-
(1992)
Br J Cancer
, vol.65
, pp. 287-291
-
-
Newlands, E.S.1
Blackledge, G.R.2
Slack, J.A.3
-
3
-
-
0031714093
-
Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: Comparison of oral, intravenous, and hepatic intra-arterial administration
-
Marzolini C, Decosterd LA, Shen F, et al. Pharmacokinetics of temozolomide in association with fotemustine in malignant melanoma and malignant glioma patients: comparison of oral, intravenous, and hepatic intra-arterial administration. Cancer Chemother Pharmacol. 1998;42:433-440.
-
(1998)
Cancer Chemother Pharmacol
, vol.42
, pp. 433-440
-
-
Marzolini, C.1
Decosterd, L.A.2
Shen, F.3
-
4
-
-
2542590281
-
Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients
-
Ostermann S, Csajka C, Buclin T, et al. Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients. Clin Cancer Res. 2004;10:3728-3736.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3728-3736
-
-
Ostermann, S.1
Csajka, C.2
Buclin, T.3
-
5
-
-
0032855728
-
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse: Temodal Brain Tumor Group
-
Yung WK, Prados MD, Yaya-Tur R, et al. Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse: Temodal Brain Tumor Group. J Clin Oncol. 1999;17:2762-2771.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2762-2771
-
-
Yung, W.K.1
Prados, M.D.2
Yaya-Tur, R.3
-
6
-
-
1042297227
-
Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations
-
Chinot OL, Barrie M, Frauger E, et al. Phase II study of temozolomide without radiotherapy in newly diagnosed glioblastoma multiforme in an elderly populations. Cancer. 2004;100:2208-2214.
-
(2004)
Cancer
, vol.100
, pp. 2208-2214
-
-
Chinot, O.L.1
Barrie, M.2
Frauger, E.3
-
7
-
-
0036788961
-
A phase II study of temozolomide in patients with newly diagnosed supratentorial malignant glioma before radiation therapy
-
Gilbert MR, Friedman HS, Kuttesch JF, et al. A phase II study of temozolomide in patients with newly diagnosed supratentorial malignant glioma before radiation therapy. Neurooncol. 2002;4:261-267.
-
(2002)
Neurooncol
, vol.4
, pp. 261-267
-
-
Gilbert, M.R.1
Friedman, H.S.2
Kuttesch, J.F.3
-
8
-
-
0034213118
-
Survival of human glioma cells treated with various combination of temozolomide and X-rays
-
van Rijn J, Heimans JJ, van den BJ, et al. Survival of human glioma cells treated with various combination of temozolomide and X-rays. Int J Radiat Oncol Biol Phys. 2000;47:779-784.
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.47
, pp. 779-784
-
-
Van Rijn, J.1
Heimans, J.J.2
Van Den, B.J.3
-
9
-
-
0036499085
-
Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide
-
Stupp R, Dietrich PY, Ostermann KS, et al. Promising survival for patients with newly diagnosed glioblastoma multiforme treated with concomitant radiation plus temozolomide followed by adjuvant temozolomide. J Clin Oncol. 2002;20:1375-1382.
-
(2002)
J Clin Oncol
, vol.20
, pp. 1375-1382
-
-
Stupp, R.1
Dietrich, P.Y.2
Ostermann, K.S.3
-
10
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-996.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
11
-
-
0032588748
-
O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: Frequency and time to tumor progression after alkylating agent-based chemotherapy
-
Silber JR, Blank A, Bobola MS, et al. O6-methylguanine-DNA methyltransferase-deficient phenotype in human gliomas: frequency and time to tumor progression after alkylating agent-based chemotherapy. Clin Cancer Res. 1999;5:807-814.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 807-814
-
-
Silber, J.R.1
Blank, A.2
Bobola, M.S.3
-
12
-
-
0032435612
-
DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma
-
Friedman HS, McLendon RE, Kerby T, et al. DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. J Clin Oncol. 1998;16:3851-3857.
-
(1998)
J Clin Oncol
, vol.16
, pp. 3851-3857
-
-
Friedman, H.S.1
McLendon, R.E.2
Kerby, T.3
-
13
-
-
0033557903
-
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia
-
Esteller M, Hamilton SR, Burger PC, et al. Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia. Cancer Res. 1999;59:793-797.
-
(1999)
Cancer Res
, vol.59
, pp. 793-797
-
-
Esteller, M.1
Hamilton, S.R.2
Burger, P.C.3
-
14
-
-
0034626988
-
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
-
Esteller M, Garcia-Foncillas J, Andion E, et al. Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med. 2000;343:1350-1354.
-
(2000)
N Engl J Med
, vol.343
, pp. 1350-1354
-
-
Esteller, M.1
Garcia-Foncillas, J.2
Andion, E.3
-
15
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, et al. MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med. 2005;352:997-1003.
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
-
16
-
-
0023930146
-
Successful chemotherapy for recurrent malignant oligodendroglioma
-
Cairncross JG, Macdonald DR. Successful chemotherapy for recurrent malignant oligodendroglioma. Ann Neurol. 1988;23:360-364.
-
(1988)
Ann Neurol
, vol.23
, pp. 360-364
-
-
Cairncross, J.G.1
Macdonald, D.R.2
-
17
-
-
0025343367
-
Successful chemotherapy for newly diagnosed aggressive oligodendroglioma
-
Macdonald DR, Gaspar LE, Cairncross JG. Successful chemotherapy for newly diagnosed aggressive oligodendroglioma. Ann Neurol. 1990;27:573-574.
-
(1990)
Ann Neurol
, vol.27
, pp. 573-574
-
-
Macdonald, D.R.1
Gaspar, L.E.2
Cairncross, J.G.3
-
18
-
-
0038352148
-
Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: The European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971
-
van den Bent MJ, Taphoorn MJ, Brandes AA, et al. Phase II study of first-line chemotherapy with temozolomide in recurrent oligodendroglial tumors: the European Organization for Research and Treatment of Cancer Brain Tumor Group Study 26971. J Clin Oncol. 2003;21:2525-2528.
-
(2003)
J Clin Oncol
, vol.21
, pp. 2525-2528
-
-
Van Den Bent, M.J.1
Taphoorn, M.J.2
Brandes, A.A.3
-
19
-
-
4143143288
-
Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions
-
Hoang-Xuan K, Capelle L, Kujas M, et al. Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions. J Clin Oncol. 2004;22:3133-3138.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3133-3138
-
-
Hoang-Xuan, K.1
Capelle, L.2
Kujas, M.3
-
20
-
-
9144274013
-
Temozolomide chemotherapy for progressive low-grade glioma: Clinical benefits and radiological response
-
Pace A, Vidiri A, Galie E, et al. Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response. Ann Oncol. 2003;14:1722-1726.
-
(2003)
Ann Oncol
, vol.14
, pp. 1722-1726
-
-
Pace, A.1
Vidiri, A.2
Galie, E.3
-
21
-
-
3042621791
-
Immunochemotherapy with rituximab and temozolomide for central nervous system lymphomas
-
Wong ET, Tishler R, Barron L, et al. Immunochemotherapy with rituximab and temozolomide for central nervous system lymphomas. Cancer. 2004;101:139-145.
-
(2004)
Cancer
, vol.101
, pp. 139-145
-
-
Wong, E.T.1
Tishler, R.2
Barron, L.3
-
22
-
-
4644348583
-
Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide
-
Enting RH, Demopoulos A, DeAngelis LM, et al. Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide. Neurology. 2004;63:901-903.
-
(2004)
Neurology
, vol.63
, pp. 901-903
-
-
Enting, R.H.1
Demopoulos, A.2
Deangelis, L.M.3
-
23
-
-
0023605735
-
Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl- imidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine
-
Stevens MF, Hickman JA, Langdon SP, et al. Antitumor activity and pharmacokinetics in mice of 8-carbamoyl-3-methyl-imidazo[5,1-d]-1,2,3,5- tetrazin-4(3H)-one (CCRG 81045; M & B 39831), a novel drug with potential as an alternative to dacarbazine. Cancer Res. 1987;47:5846-5852.
-
(1987)
Cancer Res
, vol.47
, pp. 5846-5852
-
-
Stevens, M.F.1
Hickman, J.A.2
Langdon, S.P.3
-
24
-
-
0021287831
-
O6-alkylguanine-DNA alkyltransferase activity in normal human tissues and cells
-
Grafstrom RC, Pegg AE, Trump BF, et al. O6-alkylguanine-DNA alkyltransferase activity in normal human tissues and cells. Cancer Res. 1984;44:2855-2857.
-
(1984)
Cancer Res
, vol.44
, pp. 2855-2857
-
-
Grafstrom, R.C.1
Pegg, A.E.2
Trump, B.F.3
-
25
-
-
0032188739
-
Phase I trial of temozolomide using an extended continuous oral schedule
-
Brock CS, Newlands ES, Wedge SR, et al. Phase I trial of temozolomide using an extended continuous oral schedule. Cancer Res. 1998;58:4363-4367.
-
(1998)
Cancer Res
, vol.58
, pp. 4363-4367
-
-
Brock, C.S.1
Newlands, E.S.2
Wedge, S.R.3
-
26
-
-
27944493324
-
Gliomas respond to low dose temozolomide even after following progression on a conventional 5/28 schedule
-
Perry J, Rizek P, Morrison T, et al. Gliomas respond to low dose temozolomide even after following progression on a conventional 5/28 schedule. Neurology. 2004;62:A543.
-
(2004)
Neurology
, vol.62
-
-
Perry, J.1
Rizek, P.2
Morrison, T.3
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