Crystal structure of the human LRH-1 DBD-DNA complex reveals Ftz-F1 domain positioning is required for receptor activity

Journal of Molecular Biology

Volumn 354, Issue 5, 2005, Pages 1091-1102

  Solomon, Isaac H ^a   Hager, Janet M ^a   Safi, Rachid ^b   McDonnell, Donald P ^b   Redinbo, Matthew R ^a,c,d   Ortlund, Eric A ^a,d  

^a University of North Carolina at Chapel Hill   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Development; NR5A; Nuclear receptor; Protein DNA complex; SF 1

Indexed keywords

CELL NUCLEUS RECEPTOR; DOUBLE STRANDED DNA; FUSHI TARAZU FACTOR 1 PROTEIN; GONADORELIN; MONOMER; NUCLEAR RECEPTOR COACTIVATOR 2; PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; DNA BINDING; DNA BINDING MOTIF; DNA SEQUENCE; GENE MUTATION; GENETIC TRANSCRIPTION; HUMAN; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN DOMAIN;

EID: 27944445828     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.10.009     Document Type: Article

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