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Volumn 17, Issue 6, 2005, Pages 509-527

Diagnosis of transmissible spongiform encephalopathies in animals: A review

Author keywords

BASE; BSE; CWD; Nor98; Prion; Scrapie; Transmissible spongiform encephalopathy; TSE

Indexed keywords

ANIMALIA; BOVIDAE; BOVINAE; MUS MUSCULUS;

EID: 27944437441     PISSN: 10406387     EISSN: None     Source Type: Journal    
DOI: 10.1177/104063870501700601     Document Type: Review
Times cited : (89)

References (113)
  • 1
    • 0003691192 scopus 로고
    • HSE Books, Sudbury, UK
    • th ed. HSE Books, Sudbury, UK.
    • (1995) th Ed.
  • 3
    • 0034536342 scopus 로고    scopus 로고
    • Sc in gut associated lymphoid and nervous tissue of susceptible sheep from a Romanov flock with natural scrapie
    • Sc in gut associated lymphoid and nervous tissue of susceptible sheep from a Romanov flock with natural scrapie. J Gen Virol 81:3115-3126.
    • (2000) J Gen Virol , vol.81 , pp. 3115-3126
    • Andréolotti, O.1    Berthon, P.2    Marc, D.3
  • 4
    • 85047175120 scopus 로고    scopus 로고
    • Second BSE case confirmed in the USA
    • Anonymous: 2005, Second BSE case confirmed in the USA. Vet Rec 157:2.
    • (2005) Vet Rec , vol.157 , pp. 2
  • 5
    • 0034793570 scopus 로고    scopus 로고
    • Creutzfeldt-Jakob disease in unusually young patients who consumed venison
    • Belay ED, Gambetti P, Schonberger LB, et al.: 2001, Creutzfeldt-Jakob disease in unusually young patients who consumed venison. Arch Neurol 58:1673-1678.
    • (2001) Arch Neurol , vol.58 , pp. 1673-1678
    • Belay, E.D.1    Gambetti, P.2    Schonberger, L.B.3
  • 6
    • 20044368982 scopus 로고    scopus 로고
    • Tissue distribution of bovine spongiform encephalopathy infectivity in Romney sheep up to onset of clinical disease after oral challenge
    • Bellworthy SJ, Hawkins SA, Green RB, et al.: 2005, Tissue distribution of bovine spongiform encephalopathy infectivity in Romney sheep up to onset of clinical disease after oral challenge. Vet Rec 156:197-202.
    • (2005) Vet Rec , vol.156 , pp. 197-202
    • Bellworthy, S.J.1    Hawkins, S.A.2    Green, R.B.3
  • 7
    • 0042921669 scopus 로고    scopus 로고
    • Cases of scrapie with unusual features in Norway and designation of a new type, Nor98
    • Benestad SL, Sarradin P, Thu B, et al.: 2003, Cases of scrapie with unusual features in Norway and designation of a new type, Nor98. Vet Rec 153:202-208.
    • (2003) Vet Rec , vol.153 , pp. 202-208
    • Benestad, S.L.1    Sarradin, P.2    Thu, B.3
  • 8
    • 1242321022 scopus 로고    scopus 로고
    • Distinct molecular phenotypes in bovine prion diseases
    • Biacabe A-G, Laplanche J-L, Ryder S, Baron T: 2004, Distinct molecular phenotypes in bovine prion diseases. EMBO Rep 5:110-115.
    • (2004) EMBO Rep , vol.5 , pp. 110-115
    • Biacabe, A.-G.1    Laplanche, J.-L.2    Ryder, S.3    Baron, T.4
  • 9
    • 0033999635 scopus 로고    scopus 로고
    • Cultured cell sublines highly susceptible to prion infection
    • Bosque PJ, Prusiner SB: 2000, Cultured cell sublines highly susceptible to prion infection. J Virol 74:4377-4386.
    • (2000) J Virol , vol.74 , pp. 4377-4386
    • Bosque, P.J.1    Prusiner, S.B.2
  • 10
    • 8644260825 scopus 로고    scopus 로고
    • Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP
    • Browning SR, Mason GL, Sewald T, et al.: 2004, Transmission of prions from mule deer and elk with chronic wasting disease to transgenic mice expressing cervid PrP. J Virol 78:13345-13350.
    • (2004) J Virol , vol.78 , pp. 13345-13350
    • Browning, S.R.1    Mason, G.L.2    Sewald, T.3
  • 11
    • 0028782015 scopus 로고
    • Transmission of bovine spongiform encephalopathy and scrapie to mice: Strain variation and the species barrier
    • Bruce M, Chree A, McConnell I, et al.: 1994, Transmission of bovine spongiform encephalopathy and scrapie to mice: strain variation and the species barrier. Phil Trans R Soc Lond B Sci 343:405-411.
    • (1994) Phil Trans R Soc Lond B Sci , vol.343 , pp. 405-411
    • Bruce, M.1    Chree, A.2    McConnell, I.3
  • 12
    • 0030775632 scopus 로고    scopus 로고
    • Transmissions to mice indicate that "new variant" CJD is caused by the BSE agent
    • Bruce ME, Will RG, Ironside JW, et al.: 1997, Transmissions to mice indicate that "new variant" CJD is caused by the BSE agent. Nature 389:498-501.
    • (1997) Nature , vol.389 , pp. 498-501
    • Bruce, M.E.1    Will, R.G.2    Ironside, J.W.3
  • 14
    • 1442286319 scopus 로고    scopus 로고
    • Atypical scrapie cases in Germany and France are identified by discrepant reaction patterns in BSE rapid tests
    • Buschmann A, Biacabe AG, Ziegler U, et al.: 2003, Atypical scrapie cases in Germany and France are identified by discrepant reaction patterns in BSE rapid tests. J Virol Methods 117:27-36.
    • (2003) J Virol Methods , vol.117 , pp. 27-36
    • Buschmann, A.1    Biacabe, A.G.2    Ziegler, U.3
  • 15
    • 8844267730 scopus 로고    scopus 로고
    • Biology of PrPsc accumulation in two natural scrapie-infected sheep flocks
    • Caplazi P, O'Rourke K, Wolf C, et al.: 2004, Biology of PrPsc accumulation in two natural scrapie-infected sheep flocks. J Vet Diagn Invest 16:489-496.
    • (2004) J Vet Diagn Invest , vol.16 , pp. 489-496
    • Caplazi, P.1    O'Rourke, K.2    Wolf, C.3
  • 16
    • 1542357669 scopus 로고    scopus 로고
    • Identification of a second bovine amyloidotic spongiform encephalopathy: Molecular similarities with sporadic Creutzfeldt-Jakob disease
    • Casalone C, Zanusso G, Acutis P, et al.: 2004, Identification of a second bovine amyloidotic spongiform encephalopathy: molecular similarities with sporadic Creutzfeldt-Jakob disease. Proc Natl Acad Sci U S A 101:3065-3070.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3065-3070
    • Casalone, C.1    Zanusso, G.2    Acutis, P.3
  • 17
    • 0031637686 scopus 로고    scopus 로고
    • Scrapie associated fibril detection from formaldehyde fixed brain tissue in natural cases of ovine scrapie
    • Chaplin MJ, Aldrich AD, Stack MJ: 1998, Scrapie associated fibril detection from formaldehyde fixed brain tissue in natural cases of ovine scrapie. Res Vet Sci 64:41-44.
    • (1998) Res Vet Sci , vol.64 , pp. 41-44
    • Chaplin, M.J.1    Aldrich, A.D.2    Stack, M.J.3
  • 18
    • 0036185153 scopus 로고    scopus 로고
    • Sc by immunoblotting and immunohistochemistry from natural cases of scrapie and BSE
    • Sc by immunoblotting and immunohistochemistry from natural cases of scrapie and BSE. Res Vet Sci 72:37-43.
    • (2002) Res Vet Sci , vol.72 , pp. 37-43
    • Chaplin, M.J.1    Barlow, N.2    Ryder, S.3
  • 19
    • 0029831213 scopus 로고    scopus 로고
    • Molecular analysis of prion strain variation and the etiology of "new variant" CJD
    • Collinge J, Sidle K, Meads J, et al.: 1996, Molecular analysis of prion strain variation and the etiology of "new variant" CJD. Nature 383:685-690.
    • (1996) Nature , vol.383 , pp. 685-690
    • Collinge, J.1    Sidle, K.2    Meads, J.3
  • 20
    • 27944486944 scopus 로고    scopus 로고
    • Characterisation of anti-PrP antibodies and measurement of PrP using ELISA techniques
    • ed Lehmann S, Grassi J, Birkhäuser Verlag, Berlin
    • Créminon C, Grassi, J: 2004, Characterisation of anti-PrP antibodies and measurement of PrP using ELISA techniques. In: Methods and tools in biosciences and medicine - techniques in prion research, ed Lehmann S, Grassi J, pp. 117-131. Birkhäuser Verlag, Berlin.
    • (2004) Methods and Tools in Biosciences and Medicine - Techniques in Prion Research , pp. 117-131
    • Créminon, C.1    Grassi, J.2
  • 21
    • 0032490201 scopus 로고    scopus 로고
    • Guidance on the use of PrP genotyping as an aid to the control of clinical scrapie
    • Dawson M, Hoinville LJ, Hosie BD, Hunter N: 1998, Guidance on the use of PrP genotyping as an aid to the control of clinical scrapie. Vet Rec 142:623-625.
    • (1998) Vet Rec , vol.142 , pp. 623-625
    • Dawson, M.1    Hoinville, L.J.2    Hosie, B.D.3    Hunter, N.4
  • 23
    • 26944471490 scopus 로고    scopus 로고
    • Opinion on a surveillance program for Chronic Wasting Disease (CWD) in the EU (Annex Report of the working group)
    • EFSA (European Food Safety Authority): 2004, Opinion on a surveillance program for Chronic Wasting Disease (CWD) in the EU (Annex Report of the working group). The EFSA Journal 70, 1-7.
    • (2004) The EFSA Journal , vol.70 , pp. 1-7
  • 24
    • 31644445876 scopus 로고    scopus 로고
    • Evaluation of seven new rapid post mortem BSE tests
    • EFSA (European Food Safety Authority): 2004, Evaluation of seven new rapid post mortem BSE tests. EFSA scientific report 18, 1-13.
    • (2004) EFSA Scientific Report , vol.18 , pp. 1-13
  • 25
    • 18144418908 scopus 로고    scopus 로고
    • BSE agent signatures in a goat
    • Eloit M, Adjou K, Coulpier M, et al.: 2005, BSE agent signatures in a goat. Vet Rec 156:523-524.
    • (2005) Vet Rec , vol.156 , pp. 523-524
    • Eloit, M.1    Adjou, K.2    Coulpier, M.3
  • 26
    • 85039369444 scopus 로고    scopus 로고
    • Rules for the prevention, control and eradication of certain transmissible spongiform encephalopathies (and amendments)
    • European Parliament and the council of the European Union. Regulation (EC) No 999/2001: 31.05.2001.
    • European Parliament and the council of the European Union. Regulation (EC) No 999/2001: 2001. Rules for the prevention, control and eradication of certain transmissible spongiform encephalopathies (and amendments). Official Journal of the European Communities 31.05.2001.
    • (2001) Official Journal of the European Communities
  • 27
    • 0027906543 scopus 로고
    • Transmission of bovine spongiform encephalopathy to sheep and goats
    • Foster JD, Hope J, Fraser H: 1993, Transmission of bovine spongiform encephalopathy to sheep and goats. Vet Rec 133:339-341.
    • (1993) Vet Rec , vol.133 , pp. 339-341
    • Foster, J.D.1    Hope, J.2    Fraser, H.3
  • 28
    • 0035835667 scopus 로고    scopus 로고
    • Clinical signs, histopathology and genetics of experimental transmission of BSE and natural scrapie to sheep and goats
    • Foster JD, Parnham D, Chong A, et al.: 2001, Clinical signs, histopathology and genetics of experimental transmission of BSE and natural scrapie to sheep and goats. Vet Rec 148:65-171.
    • (2001) Vet Rec , vol.148 , pp. 65-171
    • Foster, J.D.1    Parnham, D.2    Chong, A.3
  • 29
    • 0036186892 scopus 로고    scopus 로고
    • What is the basis of transmissible spongiform encephalopathy induced neurodegeneration and can it be repaired?
    • Fraser JR: 2002, What is the basis of transmissible spongiform encephalopathy induced neurodegeneration and can it be repaired? Neuropathol Appl Neurobiol 28:1-11.
    • (2002) Neuropathol Appl Neurobiol , vol.28 , pp. 1-11
    • Fraser, J.R.1
  • 30
    • 8844286175 scopus 로고    scopus 로고
    • Recognition of the Nor98 variant of scrapie in the Swedish sheep population
    • Gavier-Widén D, Nöremark M, Benestad S, et al.: 2004, Recognition of the Nor98 variant of scrapie in the Swedish sheep population J Vet Diagn Invest 16:562-567.
    • (2004) J Vet Diagn Invest , vol.16 , pp. 562-567
    • Gavier-Widén, D.1    Nöremark, M.2    Benestad, S.3
  • 31
    • 0035142430 scopus 로고    scopus 로고
    • Histological observations on the brains of symptomless 7-year-old cattle
    • Gavier-Widén D, Wells GAH, Simmons MM, et al.: 2001, Histological observations on the brains of symptomless 7-year-old cattle. J Comp Pathol 124:52-59.
    • (2001) J Comp Pathol , vol.124 , pp. 52-59
    • Gavier-Widén, D.1    Wells, G.A.H.2    Simmons, M.M.3
  • 32
    • 0028349264 scopus 로고
    • PrP genotype and agent effects in scrapie: Change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie
    • Goldmann W, Hunter N, Foster J, Hope J: 1994, PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie. J Gen Virol 75:989-995.
    • (1994) J Gen Virol , vol.75 , pp. 989-995
    • Goldmann, W.1    Hunter, N.2    Foster, J.3    Hope, J.4
  • 33
    • 0036376780 scopus 로고    scopus 로고
    • Effects of agent strain and host genotype on PrP accumulation in the brain of sheep naturally and experimentally affected with scrapie
    • González L, Martin S, Begara-McGorum I, et al.: 2002, Effects of agent strain and host genotype on PrP accumulation in the brain of sheep naturally and experimentally affected with scrapie. J Comp Pathol 126:17-29.
    • (2002) J Comp Pathol , vol.126 , pp. 17-29
    • González, L.1    Martin, S.2    Begara-McGorum, I.3
  • 34
    • 0037847400 scopus 로고    scopus 로고
    • d immunoreactivity in the brain of scrapie and BSE infected sheep: Implications on differential cell targeting and PrP processing
    • d immunoreactivity in the brain of scrapie and BSE infected sheep: implications on differential cell targeting and PrP processing. J Gen Virol 84:1339-1350.
    • (2003) J Gen Virol , vol.84 , pp. 1339-1350
    • González, L.1    Martin, S.2    Jeffrey, M.3
  • 35
    • 0037310560 scopus 로고    scopus 로고
    • Pre-clinical diagnosis of transmissible spongiform encephalopathies using rapid tests
    • Grassi J: 2003, Pre-clinical diagnosis of transmissible spongiform encephalopathies using rapid tests. Transfus Clin Biol 10:19-22.
    • (2003) Transfus Clin Biol , vol.10 , pp. 19-22
    • Grassi, J.1
  • 36
    • 0035841480 scopus 로고    scopus 로고
    • Rapid tests for the preclinical post-mortem diagnosis of BSE in central nervous system tissue
    • Grassi J, Comoy E, Simon S, et al: 2001, Rapid tests for the preclinical post-mortem diagnosis of BSE in central nervous system tissue. Vet Rec 149:577-582.
    • (2001) Vet Rec , vol.149 , pp. 577-582
    • Grassi, J.1    Comoy, E.2    Simon, S.3
  • 37
    • 14544306457 scopus 로고    scopus 로고
    • Primary isolation of the bovine spongiform encephalopathy agent in mice: Agent definition based on a review of 150 transmissions
    • Green R, Horrocks C, Wilkinson A, et al: 2005, Primary isolation of the bovine spongiform encephalopathy agent in mice: agent definition based on a review of 150 transmissions. J Comp Pathol 132:117-131.
    • (2005) J Comp Pathol , vol.132 , pp. 117-131
    • Green, R.1    Horrocks, C.2    Wilkinson, A.3
  • 38
    • 0028069275 scopus 로고
    • Hydrated autoclave pretreatment enhancement of prion immunoreactivity in formalin-fixed bovine spongiform encephalopathy-affected brain
    • Berl
    • Haritani M, Spencer YI, Wells GAH: 1994, Hydrated autoclave pretreatment enhancement of prion immunoreactivity in formalin-fixed bovine spongiform encephalopathy-affected brain. Acta Neuropathol (Berl) 87:86-90.
    • (1994) Acta Neuropathol , vol.87 , pp. 86-90
    • Haritani, M.1    Spencer, Y.I.2    Wells, G.A.H.3
  • 39
    • 0041382462 scopus 로고    scopus 로고
    • Field validation and assessment of an enzyme-linked immunosorbent assay for detecting chronic wasting disease in mule deer (Odocoileus hemionus), white-tailed deer (Odocoileus virginianus), and Rocky Mountain elk (Cervus elaphus nelsoni)
    • Hibler CP, Wilson KL, Spraker TR, et al.: 2003, Field validation and assessment of an enzyme-linked immunosorbent assay for detecting chronic wasting disease in mule deer (Odocoileus hemionus), white-tailed deer (Odocoileus virginianus), and Rocky Mountain elk (Cervus elaphus nelsoni). J Vet Diagn Invest 15:311-319.
    • (2003) J Vet Diagn Invest , vol.15 , pp. 311-319
    • Hibler, C.P.1    Wilson, K.L.2    Spraker, T.R.3
  • 40
    • 0036843096 scopus 로고    scopus 로고
    • Transmission of prion diseases by blood transfusion
    • Hunter N, Foster J, Chong A, et al.: 2002, Transmission of prion diseases by blood transfusion. J Gen Virol 83:2897-2905.
    • (2002) J Gen Virol , vol.83 , pp. 2897-2905
    • Hunter, N.1    Foster, J.2    Chong, A.3
  • 41
    • 0036853439 scopus 로고    scopus 로고
    • Occurrence and distribution of infection-specific PrP in tissues of clinical scrapie cases and cull sheep from scrapie-affected farms in Shetland
    • Jeffrey M, Begara-McGorum I, Clark S, et al.: 2002, Occurrence and distribution of infection-specific PrP in tissues of clinical scrapie cases and cull sheep from scrapie-affected farms in Shetland. J Comp Pathol 127:264-273.
    • (2002) J Comp Pathol , vol.127 , pp. 264-273
    • Jeffrey, M.1    Begara-McGorum, I.2    Clark, S.3
  • 42
    • 1642315906 scopus 로고    scopus 로고
    • Pathology and pathogenesis of bovine spongiform encephalopathy and scrapie
    • Jeffrey M, Gonzalez L: 2004, Pathology and pathogenesis of bovine spongiform encephalopathy and scrapie. Curr Topics Microbiol Immunol 284:65-97.
    • (2004) Curr Topics Microbiol Immunol , vol.284 , pp. 65-97
    • Jeffrey, M.1    Gonzalez, L.2
  • 43
    • 0037384208 scopus 로고    scopus 로고
    • Cell-associated variants of disease-specific prion protein immunolabelling are found in different sources of sheep transmissible spongiform encephalopathy
    • Jeffrey M, Martin S, González L: 2003, Cell-associated variants of disease-specific prion protein immunolabelling are found in different sources of sheep transmissible spongiform encephalopathy. J Gen Virol 84:1033-1046.
    • (2003) J Gen Virol , vol.84 , pp. 1033-1046
    • Jeffrey, M.1    Martin, S.2    González, L.3
  • 44
    • 0035659971 scopus 로고    scopus 로고
    • Differential diagnosis of infections with the bovine spongiform encephalopathy (BSE) and scrapie agents in sheep
    • Jeffrey M, Martin S, González L, et al.: 2001, Differential diagnosis of infections with the bovine spongiform encephalopathy (BSE) and scrapie agents in sheep. J Comp Pathol 125:271-284.
    • (2001) J Comp Pathol , vol.125 , pp. 271-284
    • Jeffrey, M.1    Martin, S.2    González, L.3
  • 45
    • 0034934355 scopus 로고    scopus 로고
    • Onset and distribution of tissue PrP accumulation in scrapie-affected Suffolk sheep as demonstrated by sequential necropsies and tonsillar biopsies
    • Jeffrey M, Martin S, Thomson JR, et al.: 2001, Onset and distribution of tissue PrP accumulation in scrapie-affected Suffolk sheep as demonstrated by sequential necropsies and tonsillar biopsies. J Comp Pathol 125:48-57.
    • (2001) J Comp Pathol , vol.125 , pp. 48-57
    • Jeffrey, M.1    Martin, S.2    Thomson, J.R.3
  • 46
    • 0034941197 scopus 로고    scopus 로고
    • Oral Inoculation of sheep with the agent of bovine spongiform encephalopathy (BSE). I. Onset and distribution of disease-specific PrP accumulation in brain and viscera
    • Jeffrey M, Ryder S, Martin S, et al.: 2001, Oral Inoculation of sheep with the agent of bovine spongiform encephalopathy (BSE). I. Onset and distribution of disease-specific PrP accumulation in brain and viscera. J Comp Pathol 124:280-289.
    • (2001) J Comp Pathol , vol.124 , pp. 280-289
    • Jeffrey, M.1    Ryder, S.2    Martin, S.3
  • 47
    • 2442662470 scopus 로고    scopus 로고
    • Prion protein gene heterogeneity in free-ranging white-tailed deer within the chronic wasting disease affected region of Wisconsin
    • Johnson C, Johnson J, Clayton M, et al: 2003, Prion protein gene heterogeneity in free-ranging white-tailed deer within the chronic wasting disease affected region of Wisconsin. J Wildl Dis 39:576-581.
    • (2003) J Wildl Dis , vol.39 , pp. 576-581
    • Johnson, C.1    Johnson, J.2    Clayton, M.3
  • 48
    • 2942693622 scopus 로고    scopus 로고
    • Chronic wasting disease in Canada: Part 1
    • Kahn S, Dubé C, Bates L, et al: 2004, Chronic wasting disease in Canada: part 1. Can Vet J 45:397-404.
    • (2004) Can Vet J , vol.45 , pp. 397-404
    • Kahn, S.1    Dubé, C.2    Bates, L.3
  • 49
    • 0028779748 scopus 로고
    • Epidemiological observations on spongiform encephalopathies in captive wild animals in the British Isles
    • Kirkwood JK, Cunningham AA: 1994, Epidemiological observations on spongiform encephalopathies in captive wild animals in the British Isles. Vet Rec. 24:296-303.
    • (1994) Vet Rec. , vol.24 , pp. 296-303
    • Kirkwood, J.K.1    Cunningham, A.A.2
  • 50
    • 9744287006 scopus 로고    scopus 로고
    • Clinical findings in 78 suspect cases of bovine spongiform encephalopathy in Great Britain
    • Konold T, Bone G, Ryder S, et al.: 2004, Clinical findings in 78 suspect cases of bovine spongiform encephalopathy in Great Britain. Vet Rec 155: 659-666.
    • (2004) Vet Rec , vol.155 , pp. 659-666
    • Konold, T.1    Bone, G.2    Ryder, S.3
  • 51
    • 0030613755 scopus 로고    scopus 로고
    • Prion (Prpsc)-specific epitope defined by a monoclonal-antibody
    • Korth C, Stierli B, Streit P, et al: 1997, Prion (Prpsc)-specific epitope defined by a monoclonal-antibody. Nature 390, 74-77.
    • (1997) Nature , vol.390 , pp. 74-77
    • Korth, C.1    Stierli, B.2    Streit, P.3
  • 52
    • 1842457751 scopus 로고    scopus 로고
    • Comparative molecular analysis of the abnormal prion protein in field scrapie cases and experimental bovine spongiform encephalopathy in sheep by use of Western blotting and immunohistochemical methods
    • Lezmi S, Martin S, Simon S, et al.: 2004. Comparative molecular analysis of the abnormal prion protein in field scrapie cases and experimental bovine spongiform encephalopathy in sheep by use of Western blotting and immunohistochemical methods. J Virol 78:3654-3662.
    • (2004) J Virol , vol.78 , pp. 3654-3662
    • Lezmi, S.1    Martin, S.2    Simon, S.3
  • 53
    • 7044229895 scopus 로고    scopus 로고
    • Distribution of vascular amyloid in scrapie-affected sheep with different genotypes
    • Ligios C, Dexter G, Spiropoulos J, et al.: 2004, Distribution of vascular amyloid in scrapie-affected sheep with different genotypes. J Comp Pathol 131:271-276.
    • (2004) J Comp Pathol , vol.131 , pp. 271-276
    • Ligios, C.1    Dexter, G.2    Spiropoulos, J.3
  • 54
    • 0036620684 scopus 로고    scopus 로고
    • Distinction of scrapie phenotypes in sheep by lesion profiling
    • Ligios C, Jeffrey M, Ryder SJ, et al.: 2002, Distinction of scrapie phenotypes in sheep by lesion profiling. J Comp Pathol 127:45-57.
    • (2002) J Comp Pathol , vol.127 , pp. 45-57
    • Ligios, C.1    Jeffrey, M.2    Ryder, S.J.3
  • 55
    • 1142273431 scopus 로고    scopus 로고
    • Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion
    • Llewelyn CA, Hewitt PE, Knight RS, et al: 2004, Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 363:417-421.
    • (2004) Lancet , vol.363 , pp. 417-421
    • Llewelyn, C.A.1    Hewitt, P.E.2    Knight, R.S.3
  • 57
    • 0021023167 scopus 로고
    • A protease-resistant protein is a structural component of the scrapie prion
    • McKinley, MP, Bolton DC, Prusiner SB: 1983, A protease-resistant protein is a structural component of the scrapie prion. Cell 35:57-62.
    • (1983) Cell , vol.35 , pp. 57-62
    • McKinley, M.P.1    Bolton, D.C.2    Prusiner, S.B.3
  • 58
    • 0032110683 scopus 로고    scopus 로고
    • Epidemiology of chronic wasting disease in Rocky Mountain elk
    • Miller MW, Wild MA, Williams ES: 1998, Epidemiology of chronic wasting disease in Rocky Mountain elk. J Wild Dis 34:532-538.
    • (1998) J Wild Dis , vol.34 , pp. 532-538
    • Miller, M.W.1    Wild, M.A.2    Williams, E.S.3
  • 60
    • 0034904789 scopus 로고    scopus 로고
    • Cellular prion protein status in sheep: Tissue specific biochemical signatures
    • Moudjou M, Frobert Y, Grassi J, et al.: 2001, Cellular prion protein status in sheep: tissue specific biochemical signatures. J Gen Virol 82:2017-2024.
    • (2001) J Gen Virol , vol.82 , pp. 2017-2024
    • Moudjou, M.1    Frobert, Y.2    Grassi, J.3
  • 61
    • 0042420565 scopus 로고    scopus 로고
    • Molecular analysis of cases of Italian sheep scrapie and comparison with cases of bovine spongiform encephalopathy (BSE) and experimental BSE in sheep
    • Nonno R, Esposito E, Vaccari G, et al.: 2003, Molecular analysis of cases of Italian sheep scrapie and comparison with cases of bovine spongiform encephalopathy (BSE) and experimental BSE in sheep. J Clin Microbiol 41:4127-4133.
    • (2003) J Clin Microbiol , vol.41 , pp. 4127-4133
    • Nonno, R.1    Esposito, E.2    Vaccari, G.3
  • 62
    • 0022005315 scopus 로고
    • A cellular gene encodes scrapie PrP 27-30 protein
    • Oesch, B, Westaway D, Walchli M, et al.: 1985, A cellular gene encodes scrapie PrP 27-30 protein. Cell 40:735-746.
    • (1985) Cell , vol.40 , pp. 735-746
    • Oesch, B.1    Westaway, D.2    Walchli, M.3
  • 63
  • 65
    • 7444263581 scopus 로고    scopus 로고
    • Identification of putative atypical scrapie in sheep in Portugal
    • Orge L, Galo A, Machado C, et al.: 2004, Identification of putative atypical scrapie in sheep in Portugal. J Gen Virol. 85:3487-3491.
    • (2004) J Gen Virol , vol.85 , pp. 3487-3491
    • Orge, L.1    Galo, A.2    Machado, C.3
  • 66
    • 0033823648 scopus 로고    scopus 로고
    • Preclinical diagnosis of scrapie by immunohistochemistry of third eyelid lymphoid tissue
    • O'Rourke KI, Baszler TV, Besser TE, et al.: 2000, Preclinical diagnosis of scrapie by immunohistochemistry of third eyelid lymphoid tissue. J Clin Microbiol. 38:3254-3259.
    • (2000) J Clin Microbiol , vol.38 , pp. 3254-3259
    • O'Rourke, K.I.1    Baszler, T.V.2    Besser, T.E.3
  • 67
    • 0032861299 scopus 로고    scopus 로고
    • PrP genotypes of captive and free-ranging Rocky Mountain elk (Cervus elaphus nelsoni) with chronic wasting disease
    • O'Rourke KI, Besser TE, Miller MW, et al.: 1999, PrP genotypes of captive and free-ranging Rocky Mountain elk (Cervus elaphus nelsoni) with chronic wasting disease. J Gen Virol 80:2765-2769.
    • (1999) J Gen Virol , vol.80 , pp. 2765-2769
    • O'Rourke, K.I.1    Besser, T.E.2    Miller, M.W.3
  • 68
    • 2442643832 scopus 로고    scopus 로고
    • Polymorphisms in the prion precursor functional gene but not the pseudogene are associated with susceptibility to chronic wasting disease in white-tailed deer
    • O'Rourke KI, Spraker TR, Hamburg LK, et al.: 2004, Polymorphisms in the prion precursor functional gene but not the pseudogene are associated with susceptibility to chronic wasting disease in white-tailed deer. J Gen Virol 85:1339-1346.
    • (2004) J Gen Virol , vol.85 , pp. 1339-1346
    • O'Rourke, K.I.1    Spraker, T.R.2    Hamburg, L.K.3
  • 69
    • 0034328059 scopus 로고    scopus 로고
    • Immunohistochemical diagnosis of chronic wasting disease in preclinically affected elk from a captive herd
    • Peters J, Miller JM, Jenny AL, et al.: 2000, Immunohistochemical diagnosis of chronic wasting disease in preclinically affected elk from a captive herd. J Vet Diagn Invest. 12:579-582.
    • (2000) J Vet Diagn Invest. , vol.12 , pp. 579-582
    • Peters, J.1    Miller, J.M.2    Jenny, A.L.3
  • 70
    • 0020321767 scopus 로고
    • Novel proteinaceous infectious particles cause scrapie
    • Prusiner SB: 1982, Novel proteinaceous infectious particles cause scrapie. Science 216:136-144.
    • (1982) Science , vol.216 , pp. 136-144
    • Prusiner, S.B.1
  • 72
    • 0036889148 scopus 로고    scopus 로고
    • Comparison of abnormal prion protein glycoform patterns from transmissible spongiform encephalopathy agent-infected deer, elk, sheep, and cattle
    • Race RE, Raines A, Baron TG, et al.: 2002, Comparison of abnormal prion protein glycoform patterns from transmissible spongiform encephalopathy agent-infected deer, elk, sheep, and cattle. Virology 76:12365-12368.
    • (2002) Virology , vol.76 , pp. 12365-12368
    • Race, R.E.1    Raines, A.2    Baron, T.G.3
  • 73
    • 1842687458 scopus 로고    scopus 로고
    • Demonstration of lateral transmission of scrapie between sheep kept under natural conditions using lymphoid tissue biopsy
    • Ryder S, Dexter G, Bellworthy S, Tongue S: 2004, Demonstration of lateral transmission of scrapie between sheep kept under natural conditions using lymphoid tissue biopsy. Res Vet Sci 76:211-217.
    • (2004) Res Vet Sci , vol.76 , pp. 211-217
    • Ryder, S.1    Dexter, G.2    Bellworthy, S.3    Tongue, S.4
  • 74
    • 0035814699 scopus 로고    scopus 로고
    • Immunohistochemical detection of PrP in the medulla oblongata of sheep: The spectrum of staining in normal and scrapie-affected sheep
    • Ryder SJ, Spencer YI, Bellerby PJ, March SA: 2001, Immunohistochemical detection of PrP in the medulla oblongata of sheep: the spectrum of staining in normal and scrapie-affected sheep. Vet Rec 148:7-13.
    • (2001) Vet Rec , vol.148 , pp. 7-13
    • Ryder, S.J.1    Spencer, Y.I.2    Bellerby, P.J.3    March, S.A.4
  • 75
    • 0035859102 scopus 로고    scopus 로고
    • Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding
    • Saborio GP, Permanne B, Soto C: 2001, Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding. Nature 411:810-813.
    • (2001) Nature , vol.411 , pp. 810-813
    • Saborio, G.P.1    Permanne, B.2    Soto, C.3
  • 76
    • 0031720905 scopus 로고    scopus 로고
    • Eight prion strains have PrP (Sc) molecules with different conformations
    • Safar J, Willie H, Itri V, et al.: 1998, Eight prion strains have PrP (Sc) molecules with different conformations. Nat Med 4:1157-1165.
    • (1998) Nat Med , vol.4 , pp. 1157-1165
    • Safar, J.1    Willie, H.2    Itri, V.3
  • 77
    • 0032478563 scopus 로고    scopus 로고
    • Capillary isoelectric focusing of the scrapie prion protein
    • Schmerr MJ, Cutlip RC, Jenny A: 1998, Capillary isoelectric focusing of the scrapie prion protein. J Chromatogr 802:135-141.
    • (1998) J Chromatogr , vol.802 , pp. 135-141
    • Schmerr, M.J.1    Cutlip, R.C.2    Jenny, A.3
  • 79
    • 9144258359 scopus 로고    scopus 로고
    • Monoclonal antibody against a peptide of human protein discriminates between Creutzfeldt-Jacob's disease - Affected and normal brain tissue
    • Serbec VC, Bresjanac M, Popovic M, et al.: 2003, Monoclonal antibody against a peptide of human protein discriminates between Creutzfeldt-Jacob's disease - affected and normal brain tissue. J Biol Chem 279:3694-3698.
    • (2003) J Biol Chem , vol.279 , pp. 3694-3698
    • Serbec, V.C.1    Bresjanac, M.2    Popovic, M.3
  • 80
    • 0035943651 scopus 로고    scopus 로고
    • A protease resistant PrP isoform is present in urine of animals and humans affected with prion diseases
    • Shaked GM, Shaked Y, Kaviv Z, et al.: 2001, A protease resistant PrP isoform is present in urine of animals and humans affected with prion diseases. J Biol Chem 276:31479-31482.
    • (2001) J Biol Chem , vol.276 , pp. 31479-31482
    • Shaked, G.M.1    Shaked, Y.2    Kaviv, Z.3
  • 81
  • 83
    • 0030599770 scopus 로고    scopus 로고
    • BSE in Great Britain: Consistency of the neurohistopathological findings in two random annual samples of clinically suspect cases
    • Simmons MM, Harris P, Jeffrey M, et al.: 1996, BSE in Great Britain: consistency of the neurohistopathological findings in two random annual samples of clinically suspect cases. Vet Rec 138:175-177.
    • (1996) Vet Rec , vol.138 , pp. 175-177
    • Simmons, M.M.1    Harris, P.2    Jeffrey, M.3
  • 84
    • 4844220510 scopus 로고    scopus 로고
    • Diagnosing prion diseases: Needs, challenges and hopes. Nature reviews
    • Soto, C: 2004, Diagnosing prion diseases: needs, challenges and hopes. Nature reviews, Microbiology 2:809-819.
    • (2004) Microbiology , vol.2 , pp. 809-819
    • Soto, C.1
  • 85
    • 4544282941 scopus 로고    scopus 로고
    • CWD in the obex and cranial lymphoid tissues of Rocky Mountain elk (Cervus elaphus nelsoni) with subclinical chronic wasting disease
    • CWD in the obex and cranial lymphoid tissues of Rocky Mountain elk (Cervus elaphus nelsoni) with subclinical chronic wasting disease. Vet Rec 155:295-302.
    • (2004) Vet Rec , vol.155 , pp. 295-302
    • Spraker, T.R.1    Balachandran, A.2    Zhuang, D.3    O'Rourke, K.I.4
  • 86
    • 0003073570 scopus 로고    scopus 로고
    • Validation of monoclonal antibody F99/97.6.1 for immunohistochemical staining of brain and tonsil in mule deer (Odocoileus hemionus) with chronic wasting disease
    • Spraker TR, O'Rourke KI, Balachandran A, et al.: 2002, Validation of monoclonal antibody F99/97.6.1 for immunohistochemical staining of brain and tonsil in mule deer (Odocoileus hemionus) with chronic wasting disease. J Vet Diagn Invest 14:3-7.
    • (2002) J Vet Diagn Invest , vol.14 , pp. 3-7
    • Spraker, T.R.1    O'Rourke, K.I.2    Balachandran, A.3
  • 87
    • 0036726221 scopus 로고    scopus 로고
    • Distribution of protease-resistant prion protein and spongiform encephalopathy in free-ranging mule deer (Odocoileus hemionus) with chronic wasting disease
    • Spraker TR, Zink RR, Cummings BA, et al.: 2002, Distribution of protease-resistant prion protein and spongiform encephalopathy in free-ranging mule deer (Odocoileus hemionus) with chronic wasting disease. Vet Pathol 39:546-556.
    • (2002) Vet Pathol , vol.39 , pp. 546-556
    • Spraker, T.R.1    Zink, R.R.2    Cummings, B.A.3
  • 88
    • 27944431939 scopus 로고    scopus 로고
    • Western immunoblotting techniques for the study of transmissible spongiform encephalopathies
    • ed. Lehmann S, Grassi J, Birkhäuser Verlag, Berlin
    • Stack M: 2004, Western immunoblotting techniques for the study of transmissible spongiform encephalopathies. In: Methods and tools in biosciences and medicine - techniques in prion research, ed. Lehmann S, Grassi J, pp. 97-116. Birkhäuser Verlag, Berlin.
    • (2004) Methods and Tools in Biosciences and Medicine - Techniques in Prion Research , pp. 97-116
    • Stack, M.1
  • 89
    • 8644261692 scopus 로고    scopus 로고
    • The first Canadian indigenous case of bovine spongiform encephalopathy (BSE) has molecular characteristics for prion protein that are similar to those of BSE in the United Kingdom but differ from those of chronic wasting disease in captive elk and deer
    • Stack MJ, Balachandran A, Chaplin M, Davis L: 2004, The first Canadian indigenous case of bovine spongiform encephalopathy (BSE) has molecular characteristics for prion protein that are similar to those of BSE in the United Kingdom but differ from those of chronic wasting disease in captive elk and deer. Can Vet J 45:825-830.
    • (2004) Can Vet J , vol.45 , pp. 825-830
    • Stack, M.J.1    Balachandran, A.2    Chaplin, M.3    Davis, L.4
  • 90
    • 0036938752 scopus 로고    scopus 로고
    • Differentiation of prion protein glycoforms from naturally occurring sheep scrapie, sheep passaged scrapie strains (CH1641 and SSBP1), bovine spongiform encephalopathy (BSE) cases and Romney and Cheviot breed sheep experimentally inoculated with BSE using two monoclonal antibodies
    • Berl
    • Stack MJ, Chaplin MJ, Clark J: 2002, Differentiation of prion protein glycoforms from naturally occurring sheep scrapie, sheep passaged scrapie strains (CH1641 and SSBP1), bovine spongiform encephalopathy (BSE) cases and Romney and Cheviot breed sheep experimentally inoculated with BSE using two monoclonal antibodies. Acta Neuropathol (Berl) 104:279-286.
    • (2002) Acta Neuropathol , vol.104 , pp. 279-286
    • Stack, M.J.1    Chaplin, M.J.2    Clark, J.3
  • 91
    • 0001958074 scopus 로고    scopus 로고
    • The diagnosis of bovine spongiform encephalopathy and scrapie by the detection of fibrils and the abnormal protein isoform
    • ed. Baker H, Ridley RM, Humana Press, Totowa, NJ
    • Stack MJ, Keyes P, Scott AC: 1996, The diagnosis of bovine spongiform encephalopathy and scrapie by the detection of fibrils and the abnormal protein isoform. In: Prion diseases, ed. Baker H, Ridley RM, pp. 85-103. Humana Press, Totowa, NJ.
    • (1996) Prion Diseases , pp. 85-103
    • Stack, M.J.1    Keyes, P.2    Scott, A.C.3
  • 92
    • 0027669975 scopus 로고
    • Scrapie associated fibril detection on decomposed and fixed ovine brain material
    • Stack MJ, Scott AC, Done SH, Dawson M: 1993, Scrapie associated fibril detection on decomposed and fixed ovine brain material. Res Vet Sci 55:173-178.
    • (1993) Res Vet Sci , vol.55 , pp. 173-178
    • Stack, M.J.1    Scott, A.C.2    Done, S.H.3    Dawson, M.4
  • 93
    • 0033629344 scopus 로고    scopus 로고
    • Inactivation of transmissible degenerative encephalopathy agents: A review
    • Taylor DM: 2000, Inactivation of transmissible degenerative encephalopathy agents: a review. Vet J 159:10-17.
    • (2000) Vet J , vol.159 , pp. 10-17
    • Taylor, D.M.1
  • 94
    • 0037471890 scopus 로고    scopus 로고
    • Detection of disease-specific PrP in the distal ileum of cattle exposed orally to the agent of bovine spongiform encephalopathy
    • Terry LA, Marsh S, Ryder SJ, et al.: 2003, Detection of disease-specific PrP in the distal ileum of cattle exposed orally to the agent of bovine spongiform encephalopathy. Vet Rec 152:387-392.
    • (2003) Vet Rec , vol.152 , pp. 387-392
    • Terry, L.A.1    Marsh, S.2    Ryder, S.J.3
  • 95
    • 12144291345 scopus 로고    scopus 로고
    • Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein
    • Thuring CM, Erkens JH, Jacobs JG, et al.: 2004, Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein. J Clin Microbiol 42:972-980.
    • (2004) J Clin Microbiol , vol.42 , pp. 972-980
    • Thuring, C.M.1    Erkens, J.H.2    Jacobs, J.G.3
  • 96
    • 11844258825 scopus 로고    scopus 로고
    • Immunohistochemical distinction between preclinical bovine spongiform encephalopathy and scrapie infection in sheep
    • Thuring CM, van Keulen LJ, Langeveld JP, et al.: 2005, Immunohistochemical distinction between preclinical bovine spongiform encephalopathy and scrapie infection in sheep. J Comp Pathol 132:59-69.
    • (2005) J Comp Pathol , vol.132 , pp. 59-69
    • Thuring, C.M.1    Van Keulen, L.J.2    Langeveld, J.P.3
  • 98
    • 0029299190 scopus 로고
    • Immunohistochemical detection and localization of prion protein in brain tissue of sheep with natural scrapie
    • Van Keulen LJ, Schreuder BE, Meloen RH, et al.: 1995, Immunohistochemical detection and localization of prion protein in brain tissue of sheep with natural scrapie. Vet Pathol 32:299-308.
    • (1995) Vet Pathol , vol.32 , pp. 299-308
    • Van Keulen, L.J.1    Schreuder, B.E.2    Meloen, R.H.3
  • 99
    • 15944425114 scopus 로고    scopus 로고
    • A comparison of rapid bovine spongiform encephalopathy testing methods on autolyzed bovine brain tissue
    • Wear A, Henderson K, Webster K, Patel I: 2005, A comparison of rapid bovine spongiform encephalopathy testing methods on autolyzed bovine brain tissue. J Vet Diagn Invest 17:99-103.
    • (2005) J Vet Diagn Invest , vol.17 , pp. 99-103
    • Wear, A.1    Henderson, K.2    Webster, K.3    Patel, I.4
  • 100
    • 0024973635 scopus 로고
    • Bovine spongiform encephalopathy: Diagnostic significance of vacuolar changes in selected nuclei of the medulla oblongata
    • Wells GAH, Hancock RD, Cooley WA, Richards MS: 1989, Bovine spongiform encephalopathy: diagnostic significance of vacuolar changes in selected nuclei of the medulla oblongata. Vet Rec 125:521-524.
    • (1989) Vet Rec , vol.125 , pp. 521-524
    • Wells, G.A.H.1    Hancock, R.D.2    Cooley, W.A.3    Richards, M.S.4
  • 101
    • 0032583714 scopus 로고    scopus 로고
    • Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): An update
    • Wells GA, Hawkins SA, Green RB, et al.: 1998, Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): an update. Vet Rec 142:103-106.
    • (1998) Vet Rec , vol.142 , pp. 103-106
    • Wells, G.A.1    Hawkins, S.A.2    Green, R.B.3
  • 102
    • 0023669586 scopus 로고
    • A novel progressive spongiform encephalopathy in cattle
    • Wells GA, Scott AC, Johnson CT, Gunning RF et al.: 1987, A novel progressive spongiform encephalopathy in cattle. Vet Rec 121:419-420.
    • (1987) Vet Rec , vol.121 , pp. 419-420
    • Wells, G.A.1    Scott, A.C.2    Johnson, C.T.3    Gunning, R.F.4
  • 103
    • 1642304262 scopus 로고    scopus 로고
    • The essential lesion profile of bovine spongiform encephalopathy (BSE) in cattle is unaffected by breed or route of infection
    • Wells GAH, Simmons MM: 1996, The essential lesion profile of bovine spongiform encephalopathy (BSE) in cattle is unaffected by breed or route of infection. Neuropathol Appl Neurobiol 22:453.
    • (1996) Neuropathol Appl Neurobiol , vol.22 , pp. 453
    • Wells, G.A.H.1    Simmons, M.M.2
  • 104
    • 17144393789 scopus 로고    scopus 로고
    • Pathogenesis of experimental bovine spongiform encephalopathy: Preclinical infectivity in tonsil and observations on the distribution of lingual tonsil in slaughtered cattle
    • Wells GA, Spiropoulos J, Hawkins SA, Ryder S: 2005, Pathogenesis of experimental bovine spongiform encephalopathy: preclinical infectivity in tonsil and observations on the distribution of lingual tonsil in slaughtered cattle. Vet Rec 156:401-407.
    • (2005) Vet Rec , vol.156 , pp. 401-407
    • Wells, G.A.1    Spiropoulos, J.2    Hawkins, S.A.3    Ryder, S.4
  • 105
    • 0028809091 scopus 로고
    • The neuropathology and epidemiology of bovine spongiform encephalopathy
    • Wells GAH, Wilesmith JW: 1995, The neuropathology and epidemiology of bovine spongiform encephalopathy. Brain Pathol 5:91-103.
    • (1995) Brain Pathol , vol.5 , pp. 91-103
    • Wells, G.A.H.1    Wilesmith, J.W.2
  • 106
    • 0031556235 scopus 로고    scopus 로고
    • A cohort study to examine maternally-associated risk factors for bovine spongiform encephalopathy
    • Wilesmith JW, Wells GAH, Ryan JBM, et al.: 1997, A cohort study to examine maternally-associated risk factors for bovine spongiform encephalopathy. Vet Rec 141:239-243.
    • (1997) Vet Rec , vol.141 , pp. 239-243
    • Wilesmith, J.W.1    Wells, G.A.H.2    Ryan, J.B.M.3
  • 107
    • 0036679120 scopus 로고    scopus 로고
    • Chronic wasting disease in deer and elk in North America
    • Williams ES, Miller MW: 2002, Chronic wasting disease in deer and elk in North America. Rev Sci Tech 21:305-316.
    • (2002) Rev Sci Tech , vol.21 , pp. 305-316
    • Williams, E.S.1    Miller, M.W.2
  • 108
    • 0018871326 scopus 로고
    • Chronic wasting disease of captive mule deer: A spongiform encephalopathy
    • Williams ES, Young S: 1980, Chronic wasting disease of captive mule deer: a spongiform encephalopathy. J Wild Dis 16:89-98.
    • (1980) J Wild Dis , vol.16 , pp. 89-98
    • Williams, E.S.1    Young, S.2
  • 109
    • 0027352768 scopus 로고
    • Neuropathology of chronic wasting disease of mule deer (Odocoileus hemionus) and elk (Cervus elaphus nelsoni)
    • Williams ES, Young S: 1993, Neuropathology of chronic wasting disease of mule deer (Odocoileus hemionus) and elk (Cervus elaphus nelsoni). Vet Pathol 30:36-45.
    • (1993) Vet Pathol , vol.30 , pp. 36-45
    • Williams, E.S.1    Young, S.2
  • 110
    • 0026459766 scopus 로고
    • Spongiform encephalopathy in a captive puma (Felis concolor)
    • Willoughby K, Kelly DF, Lyon DG, Wells GAH: 1992, Spongiform encephalopathy in a captive puma (Felis concolor). Vet Rec 131: 431-434.
    • (1992) Vet Rec , vol.131 , pp. 431-434
    • Willoughby, K.1    Kelly, D.F.2    Lyon, D.G.3    Wells, G.A.H.4
  • 111
    • 0026424018 scopus 로고
    • Naturally occurring scrapie-like spongiform encephalopathy in five domestic cats
    • Wyatt JM, Pearson GR, Smerdon T et al.: 1991, Naturally occurring scrapie-like spongiform encephalopathy in five domestic cats. Vet Rec 129:233-236.
    • (1991) Vet Rec , vol.129 , pp. 233-236
    • Wyatt, J.M.1    Pearson, G.R.2    Smerdon, T.3
  • 112
    • 1142299412 scopus 로고    scopus 로고
    • res) observed in an apparently healthy 23-month-old Holstein steer
    • res) observed in an apparently healthy 23-month-old Holstein steer. Jpn J Infect Dis 56:221-222.
    • (2003) Jpn J Infect Dis , vol.56 , pp. 221-222
    • Yamakawa, Y.1    Hagiwara, K.2    Nohtomi, K.3
  • 113
    • 0842277807 scopus 로고    scopus 로고
    • Antibody to DNA detects scrapie but not normal prion protein
    • Zou WQ, Zheng J, Gray DM, et al.: 2004 Antibody to DNA detects scrapie but not normal prion protein. Proc Natl Acad Sci U S A 101, 1380-1385.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 1380-1385
    • Zou, W.Q.1    Zheng, J.2    Gray, D.M.3


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