Scrapie associated fibril detection from formaldehyde fixed brain tissue in natural cases of ovine scrapie

Research in Veterinary Science

Volumn 64, Issue 1, 1998, Pages 41-44

  Chaplin, M J ^a   Aldrich, A D ^a   Stack, M J ^a  

^a VETERINARY LABORATORIES AGENCY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA; OVIS;

ANIMAL; ARTICLE; BRAIN; ELECTRON MICROSCOPY; MEDULLA OBLONGATA; PATHOLOGY; PRION; SCRAPIE; SHEEP; ULTRASTRUCTURE;

ANIMALS; BRAIN; MEDULLA OBLONGATA; MICROSCOPY, ELECTRON; PRIONS; SCRAPIE; SHEEP;

EID: 0031637686     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0034-5288(98)90113-8     Document Type: Article

References (19)

1. BOLTON, D. C , MCKINLEY, M. P. & PRUSINER, S. B. (1983) Molecular characteristics of the major scrapie prion protein. Biochemistry 23, 5898-5905
2. BRUCE, M. E. (1981) Serial studies on the development of cerebral amyloidosis and vacuolar degeneration in murine scrapie Journal of Comparative Pathology 91, 589-597
3. BRUCE, M. E., McBRIDE, P. A. & FARQUAHAR, C. F. (1989) Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie. Neuroscience Letters 102, 1-6
4. CHESEBRO, B., RACE, R., WHERLY, K , NISHIO, J., BLOOM, M., LECHNER, D. et al (1985) Identification of scrapie prion protein specific mRNA in scrapie infected and uninfected brain Nature 315, 331-333
5. DAWSON, M., MANSLEY, L. M., HUNTER, A. R., STACK, M J. & SCOTT, A C. (1987) Comparison of scrapie associated fibril detection and histology in the diagnosis of natural sheep scrapie. Veterinary Record 121, 591
6. FACEMYER, K. C. & MARCHESE-RAGONA, S P. (1989) Chemical removal of aldehyde fixatives. Proceedings RMS 24/4, 223
7. FRASER, H. (1976) The pathology of natural and experimental scrapie. In Slow Virus Diseases of Animals and Men. Vol 267 Ed. R.H. Kimberlin, Amsterdam. North Holland Publishing Company
8. FRASER, H & DICKINSON, A. G. (1968) The sequential development of the brain lesions of scrapie in three strains of mice. Journal of Comparative Pathology 78, 301-311
9. GIBBS, C. J., JOY, A., HEFFNER, R., FRANKO, M , MIYAZAKI, M., ASHER, D. M. et al (1985) Clinical and pathological features and laboratory confirmation of Creuzfeldt-Jakob disease in a recipient of pituitary-derived human growth hormone. New England Journal of Medicine 313, 734-738
10. GIBSON, P. H., SOMERVILLE, R. A. FRASER, H., FOSTER, J. D & KIMBERLIN, R. H. (1987) Scrapie associated fibrils in the diagnosis of scrapie in sheep Veterinary Record 120, 125-127
11. sc) in formalin-fixed archival brain tissues. Neuropathology and Applied Neurobiology 20, 516
12. LIBERSKI, P. P. & BROWN, P. (1993) Scrapie-associated fibrils. In Light and Electron Microscopic Neuropathology of Slow Virus Disorders. Ed. P.P. Liberski Boca Raton, CRC Press Chapter 15
13. MERZ, P. A., SOMERVILLE, R. A., WISNIEWSKI, H. M. & IQBAL, K (1981) Abnormal fibrils from scrapie infected brain. Acta Neuropathologica 54, 63-74
14. OESCH, B., WESTAWAY, D , WALCHLI, M., McKINLEY, M. P., KENT, S. B H., AEBERSOLD, R et al (1985) A cellular gene encodes scrapie PrP 27-30 protein. Cell 40, 735-746
15. SCOTT, A. C., DONE, S. H , VENABLES, C. & DAWSON, M. (1987) Detection of scrapie associated fibrils as an aid to the diagnosis of scrapie in sheep. Veterinary Record 120, 280-281
16. SCOTT, A. C., WELLS, G. A. H , CHAPLIN, M J & DAWSON, M. (1992) Bovine spongiform encephalopathy detection of fibrils in the central nervous system is not affected by autolysis Research in Veterinary Science 52, 332-336
17. STACK, M. J., SCOTT, A. C., DONE, S. H., DAWSON, M (1991) Natural Scrapie. detection of fibnls in extracts from the central nervous system of sheep The Veterinary Record 128, 539-540
18. STACK, M J., SCOTT, A. C., DONE, S. H., DAWSON, M. (1993) Scrapie associated fibril detection on decomposed and fixed ovine brain material. Research in Veterinary Science 55, 173-178
19. TINTNER, R., BROWN, P., MEDLEY-WHITE, E. T., RAPPAPORT, E B., PICCARDO, C. P & GAJDUSEK, D. C (1986) Neuropathologic verification of Creutzfeldt-Jakob disease in the exhumed American recipient of human pituitary growth hormone: epidemiologic and pathogenetic implications. Neurology 36, 932-936