Cytogenetic findings in pediatric T-lymphoblastic lymphomas: One institution's experience and a review of the literature

Pediatric and Developmental Pathology

Volumn 8, Issue 5, 2005, Pages 550-556

  Ellison, Dale A ^a   Parham, David M ^a   Sawyer, Jeffrey R ^a  

^a ARKANSAS CHILDREN S HOSPITAL   (United States)

Author keywords

Cytogenetics; Lymphoblastic lymphoma; Pediatrics

Indexed keywords

ABELSON KINASE; MIXED LINEAGE LEUKEMIA PROTEIN; PROTEIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; TRANSCRIPTION FACTOR E2A; TRANSCRIPTION FACTOR ETV6; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; CERVICAL SPINE; CHILD; CHILDHOOD CANCER; CHROMOSOME 12P; CHROMOSOME 16P; CHROMOSOME 18Q; CHROMOSOME 2P; CHROMOSOME 2Q; CHROMOSOME 7Q; CHROMOSOME 9Q; CHROMOSOME ANALYSIS; CHROMOSOME BANDING PATTERN; CHROMOSOME BREAKAGE; CHROMOSOME DELETION; CHROMOSOME INVERSION 9; CLINICAL ARTICLE; CLINICAL FEATURE; CLONAL VARIATION; CONTROLLED STUDY; CYTOGENETICS; DIAGNOSTIC VALUE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOPHENOTYPING; KARYOTYPE; KARYOTYPE 46,XX; KARYOTYPE 46,XY; KARYOTYPING; LYMPHOBLASTOMA; MALE; MEDIASTINUM; PEDIATRICS; PRIORITY JOURNAL; RETROSPECTIVE STUDY; REVIEW; T CELL LYMPHOMA; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE; X CHROMOSOME;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CYTOGENETIC ANALYSIS; FEMALE; HUMANS; KARYOTYPING; LYMPHOMA, LYMPHOBLASTIC; MALE; RETROSPECTIVE STUDIES;

EID: 27844547707     PISSN: 10935266     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10024-005-0050-7     Document Type: Review

References (49)

1. Knowles DM. Lymphoblastic lymphoma. In: Knowles DM, ed. Neoplastic Hematopathology. Baltimore, MD: Williams & Wilkins. 1992; pp 715-747.
2. Kaneko Y, Frizzera G, Shikano T, Kobayashi H, Maseki N, Sakurai M. Chromosomal and immunophenotypic patterns in T cell acute lymphoblastic leukemia (T ALL) and lymphoblastic lymphoma (LBL). Leukemia 1989;3:886-892.
3. ISCN. An International System for Human Cytogenetic Nomenclature. Basel: S. Karger, 1995.
4. Ohyashiki K, Iwabuchi A, Fujieda H, Suzuki A, Nakano M, Ohyashiki JH, Toyama K, Serizawa H, Amemiya R, Hayata Y. Change in a complex translocation involving band 7q34 and 9p- in a case of T-cell lymphoblastic lymphoma. Cancer 1990;65:1533-1537.
5. Hashimoto K, Miura I, Chyubachi A, Saito M, Miura AB. Correlations of chromosome abnormalities with histologic and immunologic characteristics in 49 patients from Akita, Japan with non-Hodgkin lymphoma. Cancer Genet Cytogenet 1995;81:56-65.
6. National Cancer Institute. CGAP: The Cancer Genome Anatomy Project. http://www.cgap.nci.nih.gov. 2003.
7. Head DR, Behm FG. Acute lymphoblastic leukemia and the lymphoblastic lymphomas of childhood. Semin Diagn Pathol 1995;12:325-334.
8. Rubin CM, Le Beau MM. Cytogenetic abnormalities in childhood acute lymphoblastic leukemia. Am J Pediatr Hematol Oncol 1991;13:201-216.
9. Kaneko Y, Variakojis D, Kluskens L, Rowley JD. Lymphoblastic lymphoma: Cytogenetic, pathologic, and immunologic studies. Int J Cancer 1982;30:273-279.
10. Li D, Noyes I, Shuler C, Milo GE. Cloning and sequencing of CATR1.3, a human gene associated with tumorigenic conversion. Proc Natl Acad Sci USA 1995;92:6409-6413.
11. Reifenberger J, Wolter M, Weber RG, Megahed M, Ruzicka T, Lichter P, Reifenberger G. Missense mutations in SMOH in sporadic basal cell carcinomas of the skin and primitive neuroectodermal tumors of the central nervous system. Cancer Res 1998;58:1798-1803.
12. Tagge EP, Hanson P, Re GG, Othersen HB Jr, Smith CD, Garvin AJ. Paired box gene expression in Wilms' tumor. J Pediatr Surg 1994;29:134-141.
13. Sorensen PH, Lynch JC, Qualman SJ, Tirabosco R, Lim JF, Maurer HM, Bridge JA, Crist WM, Triche TJ, Barr FG. PAX3-FKHR and PAX7-FKHR gene fusions are prognostic indicators in alveolar rhabdomyosarcoma: a report from the Children's Oncology Group. J Clin Oncol 2002;20:2672-2679.
14. Pilozzi E, Muller-Hermelink HK, Falini B, Wolf-Peeters C, Fidler C, Gatter K, Wainscoat J. Gene rearrangements in T-cell lymphoblastic lymphoma. J Pathol 1999;188:267-270.
15. Ferrando AA, Neuberg DS, Staunton J, Loh ML, Huard C, Raimondi SC, Behm FG, Pui CH, Downing JR, Gilliland DG, Lander ES, Golub TR, Look AT. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 2002;1:75-87.
16. Armstrong SA, Staunton JE, Silverman LB, Pieters R, den Boer ML, Minden MD, Sallan SE, Lander ES, Golub TR, Korsmeyer SJ. MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia. Nat Genet 2002;30:41-47.
17. Heerema NA, Sather HN, Sensel MG, Kraft P, Nachman JB, Steinherz PG, Lange BJ, Hutchinson RS, Reaman GH, Trigg MG, Arthur DC, Gaynon PS, Uckun FM. Frequency and clinical significance of cytogenetic abnormalities in pediatric T-lineage acute lymphoblastic leukemia: a report from the Children's Cancer Group. J Clin Oncol 1998;16:1270-1278.
18. Bayly R, LeBrun DP. Role for homodimerization in growth deregulation by E2a fusion proteins. Mol Cell Biol 2000;10:5789-5796.
19. Kletzel M, Olzewski M, Huang W, Chou PM. Utility of WT1 as a reliable tool for the detection of minimal residual disease in children with leukemia. Pediatr Dev Pathol 2002;5:269-275.
20. Kobayashi H, Espinosa R, III, Fernald AA, Begy C, Diaz MO, Le Beau MM, Rowley JD. Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization. Genes Chromosomes Cancer 1993;8:246-252.
21. Mecucci C, Michaux JL, Tricot G, Louwagie A, Van den BH. Rearrangements of the short arm of chromosome No. 6 in T-cell lymphomas. Leuk Res 1985;9:1139-1148.
22. Rubnitz JE, Downing JR, Pui CH, et al. TEL gene rearrangement in acute lymphoblastic leukemia: a new genetic marker with prognostic significance. J Clin Oncol 1997;15:1150-1157.
23. Ono Y, Fukuhara N, Yoshie O. Transcriptional activity of TAL1 in T cell acute lymphoblastic leukemia requires RBTN1 or -2 and induces TALLA1, a highly specific tumor marker of T-ALL. J Biol Chem 1997;272:4576-458116.
24. Rubin CM, Le Beau MM. Cytogenetic abnormalities in childhood acute lymphoblastic leukemia. Am J Pediatr Hematol Oncol 1991;13:202-216.
25. Reddy KS, Perkins SL. Advances in the diagnostic approach to childhood lymphoblastic malignant neoplasms. Pathol Patterns Rev 2004;122(suppl 1):S3-S18.
26. Dabaja BS, Ha CS, Thomas DA, et al. The role of local radiation therapy for mediastinal disease in adults with T-cell lymphoblastic lymphoma. Cancer 2002;94:2738-2744.
27. Morel P, Lepage E, Brice P, et al. Prognosis and treatment of lymphoblastic lymphoma in adults: a report of 80 patients. J Clin Oncol 1992;10:1078-1085.
28. Abruzzo LV, Jaffe ES, Cotelingam JD, Whang-Peng J, Del DV Jr, Medeiros LJ. T-cell lymphoblastic lymphoma with eosinophilia associated with subsequent myeloid malignancy. Am J Surg Pathol 1992;16:236-245.
29. Bloomfield CD, Arthur DC, Frizzera G, Levine EG, Peterson BA, Gajl-Peczalska KJ. Nonrandom chromosome abnormalities in lymphoma. Cancer Res 1983;43:2975-2984.
30. Bohlander SK, Muschinsky V, Schrader K, Siebert R, Schlegelberger B, Harder L, Schemmel V, Fonatsch C, Ludwig WD, Hiddemann W, Dreyling MH. Molecular analysis of the CALM/AF10 fusion: identical rearrangements in acute myeloid leukemia, acute lymphoblastic leukemia and malignant lymphoma patients. Leukemia 2000;14:93-99.
31. Chenevix-Trench G, Brown JA, Tyler GB, Behm FG. Chromosome analysis of 30 cases of non-Hodgkin's lymphoma. Med Oncol Tumor Pharmacother 1988;5:17-32.
32. Hecht F, Morgan R, Hecht BK, Smith SD. Common region on chromosome 14 in T-cell leukemia and lymphoma. Science 1984;226:1445-1447.
33. Inhorn RC, Aster JC, Roach SA, Slapak CA, Soiffer R, Tantravahi R, Stone RM. A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity. Blood 1995;85:1881-1887.
34. Konishi H, Sakurai M, Nakao H, Maseki N, Kaneko Y, Yagiri Y, Notohara K, Frizzera G. Chromosome abnormalities in malignant lymphoma in patients from Kurashiki: histological and immunophenotypic correlations. Cancer Res 1990;50:2698-2703.
35. Levine EG, Arthur DC, Frizzera G, Peterson BA, Hurd DD, Bloomfield CD. There are differences in cytogenetic abnormalities among histologic subtypes of the non-Hodgkin's lymphomas. Blood 1985;66:1414-1422.
36. Maitra A, McKenna RW, Weinberg AG, Schneider NR, Kroft SH. Precursor B-cell lymphoblastic lymphoma. A study of nine cases lacking blood and bone marrow involvement and review of the literature. Am J Clin Pathol 2001;115:868-875.
37. Maseki N, Kaneko Y, Sakurai M, Kurihara M, Sampi K, Shimamura K, Takayama S. Chromosome abnormalities in malignant lymphoma in patients from Saitama. Cancer Res 1987;47:6767-6775.
38. Mikraki V, Jhanwar SC, Filippa DA, Wollner N, Chaganti RSK. Distinct patterns of chromosome abnormalities characterize childhood non-Hodgkin's lymphoma. Br J Haematol 1992;80:15-20.
39. Nomdedeu JF, Melo M, Lopez O, Rivera J, Aventin A, Sierra J. T-cell lymphoblastic lymphoma associated with the t(6;11)(q27;q23). Haematologica 2001;86:218-219.
40. Offit K, Parsa NZ, Jhanwar SC, Filippa D, Wachtel M, Chaganti RS. Clusters of chromosome 9 aberrations are associated with clinico-pathologic subsets of non-Hodgkin's lymphoma. Genes Chromosomes Cancer 1993;7:1-7.
41. Okada M, Tada M, Kanda N, Masuda M, Mizoguchi H, Kazuma M, Wada E, Kubota K, Nomura Y. C-myb gene analysis in T-cell malignancies with del(6q). Cancer Genet Cytogenet 1990;48:229-236.
42. Pollak C, Hagemeijer A. Abnormalities of the short arm of chromosome 9 with partial loss of material in hematological disorders. Leukemia 1987;1:541-548.
43. Sano K, Goji J, Kosaka Y, Nakamura H, Nakamura F, Tatsumi E. Translocation (10;12)(q24;q15) in a T-cell lymphoblastic lymphoma with myeloid hyperplasia. Cancer Genet Cytogenet 1998;105:168-171.
44. Schouten HC, Sanger WG, Weisenburger DD, Anderson J, Armitage JO. Nebraska Lymphoma Study Group. Chromosomal abnormalities in untreated patients with non-Hodgkin's lymphoma: associations with histology, clinical characteristics, and treatment outcome. Blood 1990;75:1841-1847.
45. Shikano T, Arioka H, Kobayashi R, Naito H, Ishikawa Y, Nakadate H, Hatae Y, Takeda T. Acute lymphoblastic leukemia and non-Hodgkin's lymphoma with mediastinal mass - a study of 23 children; different disorders or different stages? Leuk Lymphoma 1994;13:161-167.
46. Slavutsky I, Andreoli G, Gutierrez M, Narbaitz M, Lucero G, Eppinger M. Variant (8;22) translocation in lymphoblastic lymphoma. Leuk Lymphoma 1996;21:169-172.
47. Thandla S, Alashari M, Green DM, Aplan PD. Therapy-related T cell lymphoblastic lymphoma with t(11;19) (q23;p13) and MLL gene rearrangement. Leukemia 1999;13:2116-2118.
48. Thangavelu M, Huang B, Lemieux M, Tom W, Richkind KF. A t(4;11)(q21;p15) in a case of T-cell lymphoma and a case of acute myelogenous leukemia. Cancer Genet Cytogenet 2002;132:109-115.
49. Wan TS, Ma SK, Chan GC, Ching LM, Ha SY, Chan LC. Complex cytogenetic abnormalities in T-lymphoblastic lymphoma: resolution by spectral karyotyping. Cancer Genet Cytogenet 2000;118:24-27.