Mapping the in vivo distribution of herpes simplex virions

Human Gene Therapy

Volumn 9, Issue 11, 1998, Pages 1543-1549

  Schellingerhout, Dawid ^b   Bogdanov Jr , Alexei ^b   Marecos, Edgardo ^b   Spear, Matthew ^b   Breakefield, Xandra ^b   Weissleder, Ralph ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

INDIUM 111; TRACER;

ANIMAL EXPERIMENT; ARTICLE; BLOOD; HERPES SIMPLEX VIRUS; IMAGING; ISOTOPE LABELING; LIVER; NONHUMAN; ORGAN DISTRIBUTION; RAT; SPLEEN; VIRUS DETECTION; VIRUS PARTICLE;

ANIMALIA; HERPES; SIMPLEXVIRUS;

EID: 0032551583     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1998.9.11-1543     Document Type: Article

References (5)

1. ANDERSEN, J.K., GARBER, D.A., MEANEY, C.A., and BREAKE-FIELD, X.O. (1992). Gene transfer into mammalian central nervous system using herpes virus vectors: Extended expression of bacterial lacZ in neurons using the neuron-specific enolase promoter. Hum. Gene Ther. 3, 487-499.
2. ARMENTANO, D., ZABNER, J., SACKS, C., SOOKDEO, C., SMITH, M., GEORGE, J., WADSWORTH, S., SMITH, A., and GREGORY, R. (1997). Effect of the E4 region on the persistence of transgene expression from adenovirus vectors. J. Virol. 71, 2408-2416.
3. BELLON, G., MICHEL-CALEMARD, L., THOUVENOT, D., JAGNEAUX, V., POITEVIN, F., MALCUS, C., ACCORT, N., LAYANI, M.P., AYMAR, M., BERMON, H., BIENVENU, J., COURTNEY, M., DORING, G., GILLY, B., GILLY, R., LAMY, D., LEUVEY, H., MOREL, Y., PAULIN, C., PERRAUD, F., RODILLON, L., SENE, C., SO, S., TOURAINE-MOULIN, F., PAVIRANI, A., et al. (1997). Aerosol administration of a recombinant adenovirus expressing CFTR to cystic fibrosis patients: A phase I clinical trial. Hum. Gene Ther. 8, 15-25.
4. BREAKEFIELD, X.O., PECHAN, P., JOHNSTON, K., and JACOBY, D. (1998). Herpes virus vectors. In Stem Cell Biology and Gene Therapy. (Wiley-Liss, New York) in press.
5. CHIOCCA, E.A., CHOI, B.B., CAI, W.Z., DELUCA, N.A., SCHAFFER, P.A., DIFIGLIA, M., BREAKEFIELD, X.O., and MARTUZA, R.L. (1990). Transfer and expression of the lacZ gene in rat brain neurons mediated by herpes simplex virus mutants. New Biol. 2, 739-746.