Knockouts and transgenics confirm the importance of adrenomedullin in the vasculature

Trends in Pharmacological Sciences

Volumn 22, Issue 2, 2001, Pages 57-59

  Hay, Debbie L ^a   Smith, David M ^a  

^a IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENOMEDULLIN; GENE PRODUCT;

CONFERENCE PAPER; GENE DELETION; GENE EXPRESSION REGULATION; PRIORITY JOURNAL; RECEPTOR BINDING; REPERFUSION INJURY; VASCULAR RESISTANCE; VASCULARIZATION;

ADRENOMEDULLIN; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BLOOD VESSELS; MICE; MICE, KNOCKOUT; PEPTIDES; RECEPTORS, PEPTIDE;

EID: 0035252638     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(00)01617-5     Document Type: Conference Paper

References (8)

1. Adrenomedullin: A novel hypotensive peptide isolated from human phaeochromocytoma
2. Adrenomedullin, a multifunctional regulatory peptide
3. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
4. Visualization of the calcitonin receptor-like receptor and its receptor activity-modifying proteins during internalisation and recycling
5. Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive Dahl salt-sensitive rats
6. Hypotension and resistance to lipopolysaccharide-induced shock in transgenic mice overexpressing adrenomedullin in their vasculature
7. Mice lacking α-calcitonin gene-related peptide exhibit normal cardiovascular regulation and neuromuscular development
8. PCR display identifies tamoxifen induction of the novel angiogenic factor adrenomedullin by a non-estrogenic mechanism in the human endometrium