-
1
-
-
0024852986
-
Tumor suppressor genes: The puzzle and the promise
-
Sager R: Tumor suppressor genes: the puzzle and the promise. Science 1989;246:1406-1412.
-
(1989)
Science
, vol.246
, pp. 1406-1412
-
-
Sager, R.1
-
2
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden M, Frommer M: CpG islands in vertebrate genomes. J Mol Biol 1987;196:261-282.
-
(1987)
J Mol Biol
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
3
-
-
0012959217
-
Aberrant DNA methylation in cancer: Potential clinical interventions
-
Strathdee G, Brown R: Aberrant DNA methylation in cancer: potential clinical interventions. Exp Rev Mol Med 2002;4:1-17.
-
(2002)
Exp Rev Mol Med
, vol.4
, pp. 1-17
-
-
Strathdee, G.1
Brown, R.2
-
4
-
-
0020489781
-
Amount and distribution of 5-methylcytosine in human DNA from different types of cells
-
Ehrlich M, Gama-Sosa MA, Huang LH, Midgett RM, Kuo KC, McCune RA, Gehrke C: Amount and distribution of 5-methylcytosine in human DNA from different types of cells. Nucleic Acids Res 1982;10:2709-2721.
-
(1982)
Nucleic Acids Res
, vol.10
, pp. 2709-2721
-
-
Ehrlich, M.1
Gama-Sosa, M.A.2
Huang, L.H.3
Midgett, R.M.4
Kuo, K.C.5
McCune, R.A.6
Gehrke, C.7
-
5
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird AP: CpG-rich islands and the function of DNA methylation. Nature 1986;321:209-212.
-
(1986)
Nature
, vol.321
, pp. 209-212
-
-
Bird, A.P.1
-
6
-
-
0035321333
-
Role of DNA methylation and histone acetylation in steroid receptor expression in breast cancer
-
Yan L, Yang X, Davidson NE: Role of DNA methylation and histone acetylation in steroid receptor expression in breast cancer. J Mammary Gland Biol Neoplasia 2001;6:183-192.
-
(2001)
J Mammary Gland Biol Neoplasia
, vol.6
, pp. 183-192
-
-
Yan, L.1
Yang, X.2
Davidson, N.E.3
-
7
-
-
0021950948
-
Hypomethylation of DNA from benign and malignant human colon neoplasms
-
Goelz SE, Vogelstein B, Hamilton SR, Feinberg AP: Hypomethylation of DNA from benign and malignant human colon neoplasms. Science 1985;228:187-190.
-
(1985)
Science
, vol.228
, pp. 187-190
-
-
Goelz, S.E.1
Vogelstein, B.2
Hamilton, S.R.3
Feinberg, A.P.4
-
9
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
Baylin SB, Esteller M, Rountree MR, Bachman KE, Schuebel K, Herman JG: Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Hum Mol Genet 2001;10:687-692.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
Bachman, K.E.4
Schuebel, K.5
Herman, J.G.6
-
10
-
-
0032960181
-
Cancer epigenetics comes of age
-
Jones P, Laird PW: Cancer epigenetics comes of age. Nat Genet 1999;21:163-167.
-
(1999)
Nat Genet
, vol.21
, pp. 163-167
-
-
Jones, P.1
Laird, P.W.2
-
11
-
-
13144266670
-
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma
-
USA
-
Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, Markowitz S, Willson JK, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB: Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci USA 1998;95:6870-6875.
-
(1998)
Proc Natl Acad Sci
, vol.95
, pp. 6870-6875
-
-
Herman, J.G.1
Umar, A.2
Polyak, K.3
Graff, J.R.4
Ahuja, N.5
Issa, J.P.6
Markowitz, S.7
Willson, J.K.8
Hamilton, S.R.9
Kinzler, K.W.10
Kane, M.F.11
Kolodner, R.D.12
Vogelstein, B.13
Kunkel, T.A.14
Baylin, S.B.15
-
12
-
-
0032997736
-
MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers
-
Simpkins SB, Bocker T, Swisher EM, Mutch DG, Gersell DJ, Kovatich AJ, Palazzo JP, Fishel R, Goodfellow PJ: MLH1 promoter methylation and gene silencing is the primary cause of microsatellite instability in sporadic endometrial cancers. Hum Mol Genet 1999;8:661-666.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 661-666
-
-
Simpkins, S.B.1
Bocker, T.2
Swisher, E.M.3
Mutch, D.G.4
Gersell, D.J.5
Kovatich, A.J.6
Palazzo, J.P.7
Fishel, R.8
Goodfellow, P.J.9
-
13
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D: 5′ CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995;1:686-692.
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
Baylin, S.B.7
Sidransky, D.8
-
14
-
-
0035018273
-
The new human tissue kallikrein gene family: Structure, function and association to disease
-
Yousef GM, Diamandis EP: The new human tissue kallikrein gene family: structure, function and association to disease. Endocr Rev 2001;22:184-204.
-
(2001)
Endocr Rev
, vol.22
, pp. 184-204
-
-
Yousef, G.M.1
Diamandis, E.P.2
-
15
-
-
0034159946
-
The new human kallikrein gene family: Implications in carcinogenesis
-
Diamandis EP, Yousef GM, Luo L, Magklara A, Obiezu CV: The new human kallikrein gene family: implications in carcinogenesis. Trends Endocrinol Metab 2000;11:54-60.
-
(2000)
Trends Endocrinol Metab
, vol.11
, pp. 54-60
-
-
Diamandis, E.P.1
Yousef, G.M.2
Luo, L.3
Magklara, A.4
Obiezu, C.V.5
-
17
-
-
0033592538
-
Cancer biology: Extracellular proteinases in malignancy
-
Matrisian LM: Cancer biology: extracellular proteinases in malignancy. Curr Biol 1999;9:R776-R778.
-
(1999)
Curr Biol
, vol.9
-
-
Matrisian, L.M.1
-
18
-
-
0021780949
-
Plasminogen activators, tissue degradation and cancer
-
Dano K, Andreasen PA, Grondahl-Hansen J, Kristensen P, Nielsen LS, Skriver L: Plasminogen activators, tissue degradation and cancer. Adv Cancer Res 1985;44:139-266.
-
(1985)
Adv Cancer Res
, vol.44
, pp. 139-266
-
-
Dano, K.1
Andreasen, P.A.2
Grondahl-Hansen, J.3
Kristensen, P.4
Nielsen, L.S.5
Skriver, L.6
-
20
-
-
0035176717
-
Tumor progression: Defining the soil round the tumor seed
-
McCawley LJ, Matrisian LM: Tumor progression: defining the soil round the tumor seed. Curr Biol 2001;11:R25-R27.
-
(2001)
Curr Biol
, vol.11
-
-
McCawley, L.J.1
Matrisian, L.M.2
-
21
-
-
0029901712
-
Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression
-
Liu XL, Wazer DE, Watanabe K, Band V: Identification of a novel serine protease-like gene, the expression of which is down-regulated during breast cancer progression. Cancer Res 1996;56:3371-3379.
-
(1996)
Cancer Res
, vol.56
, pp. 3371-3379
-
-
Liu, X.L.1
Wazer, D.E.2
Watanabe, K.3
Band, V.4
-
22
-
-
0035134145
-
Immunofluorometric assay of human kallikrein 10 and its detection in biological fluids and tissues
-
Luo LY, Grass L, Howarth DJC, Thibault P, Ong H, Diamandis EP: Immunofluorometric assay of human kallikrein 10 and its detection in biological fluids and tissues. Clin Chem 2001;47:237-246.
-
(2001)
Clin Chem
, vol.47
, pp. 237-246
-
-
Luo, L.Y.1
Grass, L.2
Howarth, D.J.C.3
Thibault, P.4
Ong, H.5
Diamandis, E.P.6
-
23
-
-
0032212444
-
The role for NES1 serine protease as a novel tumor suppressor
-
Goyal J, Smith KM, Cowan JM, Wazer DE, Lee SW, Band V: The role for NES1 serine protease as a novel tumor suppressor. Cancer Res 1996;58:4782-4786.
-
(1996)
Cancer Res
, vol.58
, pp. 4782-4786
-
-
Goyal, J.1
Smith, K.M.2
Cowan, J.M.3
Wazer, D.E.4
Lee, S.W.5
Band, V.6
-
24
-
-
0035503704
-
CpG methylation as a basis for breast tumor-specific loss of NES1/kallikreins 10 expression
-
Li B, Goyal J, Dhar S, Dimri G, Evron E, Sukumar S, Wazer DE, Band V: CpG methylation as a basis for breast tumor-specific loss of NES1/kallikreins 10 expression. Cancer Res 2001;61:8014-8021.
-
(2001)
Cancer Res
, vol.61
, pp. 8014-8021
-
-
Li, B.1
Goyal, J.2
Dhar, S.3
Dimri, G.4
Evron, E.5
Sukumar, S.6
Wazer, D.E.7
Band, V.8
-
25
-
-
0036534440
-
Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast, testicular, and ovarian cancers
-
Bharaj BB, Luo LY, Jung K, Stephan C, Diamandis EP: Identification of single nucleotide polymorphisms in the human kallikrein 10 (KLK10) gene and their association with prostate, breast, testicular, and ovarian cancers. Prostate 2002;51:35-41.
-
(2002)
Prostate
, vol.51
, pp. 35-41
-
-
Bharaj, B.B.1
Luo, L.Y.2
Jung, K.3
Stephan, C.4
Diamandis, E.P.5
-
26
-
-
0034938562
-
Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue
-
Luo LY, Rajpert-De Meyts ER, Jung K, Diamandis EP: Expression of the normal epithelial cell-specific 1 (NES1; KLK10) candidate tumour suppressor gene in normal and malignant testicular tissue. Br J Cancer 2001;85:220-224.
-
(2001)
Br J Cancer
, vol.85
, pp. 220-224
-
-
Luo, L.Y.1
Rajpert-De Meyts, E.R.2
Jung, K.3
Diamandis, E.P.4
-
27
-
-
0037442754
-
The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis
-
Luo LY, Katsaros D, Scorilas A, Fracchioli S, Bellino R, Van Gramberen M, de Bruijn H, Henrik A, Stenman UH, Massabrio M, van der Zee AG, Vergote I, Diamandis EP: The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis. Cancer Res 2003;63:807-811.
-
(2003)
Cancer Res
, vol.63
, pp. 807-811
-
-
Luo, L.Y.1
Katsaros, D.2
Scorilas, A.3
Fracchioli, S.4
Bellino, R.5
Van Gramberen, M.6
De Bruijn, H.7
Henrik, A.8
Stenman, U.H.9
Massabrio, M.10
Van Der Zee, A.G.11
Vergote, I.12
Diamandis, E.P.13
-
28
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden M, Frommer M: CpG islands in vertebrate genomes. J Mol Biol 1987;196:261-282.
-
(1987)
J Mol Biol
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
29
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
USA
-
Herman JG, Graff JR, Myohanen S, Nelkin BD, Baylin SB: Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 1996;93:9821-9826.
-
(1996)
Proc Natl Acad Sci
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
30
-
-
0029114538
-
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas
-
USA
-
Yoshiura K, Kanai Y, Ochiai A, Shimoyama Y, Sugimura T, Hirohashi S: Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc Natl Acad Sci USA 1995;92:7416-7419.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 7416-7419
-
-
Yoshiura, K.1
Kanai, Y.2
Ochiai, A.3
Shimoyama, Y.4
Sugimura, T.5
Hirohashi, S.6
-
31
-
-
0022283817
-
Molecular, cellular and animal pharmacology of 5-aza-2′- deoxycytidine
-
Momparler RL: Molecular, cellular and animal pharmacology of 5-aza-2′-deoxycytidine. Pharmacol Ther 1985;30:287-299.
-
(1985)
Pharmacol Ther
, vol.30
, pp. 287-299
-
-
Momparler, R.L.1
-
32
-
-
0037438985
-
Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers
-
Yuan BZ, Durkin ME, Papescu NC: Promoter hypermethylation of DLC-1, a candidate tumor suppressor gene, in several common human cancers. Cancer Genet Cytogenet 2003;140:113-117.
-
(2003)
Cancer Genet Cytogenet
, vol.140
, pp. 113-117
-
-
Yuan, B.Z.1
Durkin, M.E.2
Papescu, N.C.3
-
33
-
-
0029092566
-
Tumor markers in the management of patients with ovarian cancer
-
Tuxen MK, Soletormos G, Dombernowsky P: Tumor markers in the management of patients with ovarian cancer. Cancer Treat Rev 1995;21:215-245.
-
(1995)
Cancer Treat Rev
, vol.21
, pp. 215-245
-
-
Tuxen, M.K.1
Soletormos, G.2
Dombernowsky, P.3
-
34
-
-
0035116695
-
6-methylguanine- DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients
-
6- methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients. Cancer Res 2001;3:939-942.
-
(2001)
Cancer Res
, vol.3
, pp. 939-942
-
-
Rosas, S.L.1
Koch, W.2
Da Costa Carvalho, M.G.3
Wu, L.4
Califano, J.5
Westra, W.6
Jen, J.7
Sidransky, D.8
-
35
-
-
0037357246
-
DNA methylation as a cancer-specific biomarker: From molecules to populations
-
Patel A, Groopman JD, Umar A: DNA methylation as a cancer-specific biomarker: from molecules to populations. Ann NY Acad Sci 2003;983:286-297.
-
(2003)
Ann NY Acad Sci
, vol.983
, pp. 286-297
-
-
Patel, A.1
Groopman, J.D.2
Umar, A.3
-
36
-
-
0033822364
-
Large-scale human promoter mapping using CpG islands
-
Ioshikhes IP, Zhang MQ: Large-scale human promoter mapping using CpG islands. Nat Genet 2000;26:61-63.
-
(2000)
Nat Genet
, vol.26
, pp. 61-63
-
-
Ioshikhes, I.P.1
Zhang, M.Q.2
|