Differences in the single-oral-dose pharmacokinetics and urinary excretion of paracetamol and its conjugates between Hong Kong Chinese and Caucasian subjects

Journal of Clinical Pharmacy and Therapeutics

Volumn 30, Issue 2, 2005, Pages 179-184

  Critchley, J A J H ^a   Critchley, Lester A H ^a   Anderson, P J ^a   Tomlinson, B ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Chinese; Conjugates; Ethnics differences; Paracetamol; Pharmacokinetics

Indexed keywords

ACETYLCYSTEINE; CYSTEINE; GLUCURONIDE; PARACETAMOL; SULFATE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CAUCASIAN; CHINESE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG EXCRETION; DRUG METABOLISM; DRUG URINE LEVEL; ETHNIC DIFFERENCE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HONG KONG; HUMAN; HUMAN EXPERIMENT; KIDNEY CLEARANCE; MALE; NORMAL HUMAN; PHARMACOGENETICS; URINARY EXCRETION;

ACETAMINOPHEN; ADMINISTRATION, ORAL; ADULT; AREA UNDER CURVE; ASIAN CONTINENTAL ANCESTRY GROUP; BODY HEIGHT; BODY WEIGHT; CYSTEINE; DRUG ADMINISTRATION SCHEDULE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCURONIDES; HALF-LIFE; HONG KONG; HUMANS; MALE; METABOLIC CLEARANCE RATE; SULFATES;

EID: 27744552423     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2004.00626.x     Document Type: Article

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