Protein electrostriction: A possibility of elastic deformation of the α-hemolysin channel by the applied field

European Biophysics Journal

Volumn 34, Issue 8, 2005, Pages 997-1006

  Krasilnikov, Oleg V ^a   Merzlyak, Petr G ^a   Yuldasheva, Liliya N ^a   Capistrano, Maria F ^b  

^a FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO NORTE   (Brazil)

Author keywords

Blockage; Bottleneck barriers; Crowns; Generalized Woodhull model; van der Waals interactions

Indexed keywords

18 CROWN 6; ALPHA HEMOLYSIN; CROWN ETHER; HEMOLYSIN; ION CHANNEL; POTASSIUM ION; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CIS ISOMER; CRYSTAL STRUCTURE; ELASTICITY; ELECTRIC FIELD; ION CONDUCTANCE; LIPID BILAYER; MOLECULAR INTERACTION; MOLECULAR PROBE; POROSITY; STAPHYLOCOCCUS AUREUS;

BACTERIAL TOXINS; COMPUTER SIMULATION; CROWN COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELASTICITY; ELECTROMAGNETIC FIELDS; HEMOLYSIN PROTEINS; ION CHANNEL GATING; LIPID BILAYERS; MEMBRANE FLUIDITY; MODELS, CHEMICAL; MODELS, MOLECULAR; PHOSPHATIDYLCHOLINES; POROSITY; PROTEIN CONFORMATION; RADIATION DOSAGE;

STAPHYLOCOCCUS AUREUS;

EID: 27744551094     PISSN: 01757571     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00249-005-0485-9     Document Type: Article

References (29)

1. Alcaraz A, Nestorovich EM, Aguilella-Arzo M, Aguilella VM, Bezrukov SM (2004) Salting out the ionic selectivity of a wide channel: the asymmetry of OmpF. Biophys J 87:943-957
2. Allen MP, Tildesley DJ (1989) Computer simulation of liquids. Oxford Science Publication, Oxford
3. Barry PH, Lynch JW (1991) Liquid junction potentials and small cell effects in patch-clamp analysis. J Membr Biol 121:101-117
4. Bezrukov SM, Krasilnikov OV, Yuldasheva LN, Berezhkovskii AM, Rodrigues CG (2004) Field-dependent effect of crown ether (18-crown-6) on ionic conductance of α-Hemolysin channels. Biophys J 87:3162-3171
5. Felder CE, Botti SA, Lifson S, Silman I, Sussman JL (1997) External and internal electrostatic potentials of cholinesterase models. J Mol Graph Model 15:318-327
6. Gouaux JE, Braha O, Hobaugh MR, Song L, Cheley S, Shustak C, Bayley H (1994) Subunit stoichiometry of staphylococcal alpha-hemolysin in crystals and on membranes: a heptameric transmembrane pore. Proc Natl Acad Sci USA 91:12828-12831
7. Gray GS, Kehoe M (1984) Primary sequence of the alpha-toxin gene from Staphylococcus aureus Wood 46. Infect Immun 46:615-618
8. Gu LQ, Cheley S, Bayley H (2003) Electroosmotic enhancement of the binding of a neutral molecule to a transmembrane pore. Proc Natl Acad Sci USA 100:15498-15503
9. Guex N, Peitsch MC (1997) SWISS-MODEL and the Swiss-Pdb-Viewer: an environment for comparative protein modeling. Electrophoresis 18(15):2714-2723
10. Hille B (1992) Ionic channels of excitable membranes. Sinauer Associates Inc, Sunderland, MA
11. Howorka S, Bayley H (2002) Probing distance and electrical potential within a protein pore with tethered DNA. Biophys J 83(6):3202-3210
12. Krasilnikov OV, Ternovsky VI, Musaev YuM, Tashmukhamedov BA (1980) Influence of staphylotoxin on conductance of bilayer phospholipid membranes. Doklady AN UzSSR 7:66-68
13. Krasilnikov OV, Ternovsky VI, Tashmukhamedov BA (1981) Properties of ion channels induced by alpha-staphylotoxin in bilayer lipid membranes. Biofizika 26:271-276
14. Krasilnikov OV, Merzlyak PG, Yuldasheva LN, Rodrigues CG, Bhakdi S, Valeva A (2000) Electrophysiological evidence for heptameric stoichiometry of ion channels formed by Staphylococcus aureus alpha-toxin in planar lipid bilayers. Mol Microbiol 37:1372-1378
15. Merzlyak PG, Yuldasheva LN, Rodrigues CG, Carneiro CMM, Krasilnikov OV, Bezrukov SM (1999) Polymeric non-electrolytes to probe pore geometry: application to the alpha-toxin transmembrane channel. Biophys J 77:3023-3033
16. Montal M, Mueller P (1972) Formation of bimolecular membranes from lipid monolayers and a study of their electrical properties. Proc Natl Acad Sci USA 69:3561-3566
17. Movileanu L, Cheley S, Howorka S, Braha O, Bayley H (2001) Location of a constriction in the lumen of a transmembrane pore by targeted covalent attachment of polymer molecules. J Gen Physiol 117:239-252
18. Noskov SYu, Im W, Roux B (2004) Ion permeation through the α-Hemolysin channel: theoretical studies based on brownian dynamics and poisson-nernst-plank electrodiffusion theory. Biophys J 87:2299-2309
19. Ozutsumi K, Ishiguro SI (1992) A precise calorimetric study of 18-crown-6 complexes with sodium, potassium, rubidium, cesium, and ammonium ions in aqueous solution. Bull Chem Soc Jpn 65:1173-1175
20. Parsegian VA (2004) van der Waals forces. Cambridge University Press (in press)
21. Parsegian VA, Weiss GH (1974) Electrodynamic interactions between curved parallel surfaces. J Phys Chem 60:5080-5085
22. Pedersen CJ (1967) Cyclic polyethers and their complexes with metal salts. J Am Chem Soc 89:7017-7036
23. Pedersen CJ (1968) Ionic complexes of macrocyclic polyethers. Fed Proc 27:1305-1309
24. Pedersen CJ (1988) The discovery of crown ethers. Science 241:536-540
25. Rounaghi G, Eshaghi Z, Ghiamati E (1977) Thermodynamic study of complex formation between 18-crown-6 and potassium ion in some binary non-aqueous solvents using a conductometric method. Talanta 44:275-282
26. Song L, Hobaugh MR, Shustak C, Cheley S, Bayley H, Gouaux JE (1996) Structure of staphylococcal α-hemolysin, a heptameric transmembrane pore. Science 274:1859-1866
27. Tikhonov DB, Magazanik LG (1998) Voltage dependence of open channel blockage: onset and offset rates. J Membr Biol 161:1-8
28. Woodhull AN (1973) Ionic blockage of sodium channels in nerve. J Gen Physiol 61:687-708
29. Zaccai G (2000) How soft is a protein? A protein dynamics force constant measured by neutron scattering. Science 288:1604-1607