Gastroprotective action of glucocorticoid hormones in rats with desensitization of capsaicin-sensitive sensory neurons

Inflammopharmacology

Volumn 13, Issue 1-3, 2005, Pages 217-228

  Bobryshev, P ^a   Bagaeva, T ^a   Filaretova, L ^a  

^a PAVLOV INSTITUTE OF PHYSIOLOGY   (Russian Federation)

Author keywords

Capsaicin sensitive neurons; Gastric erosions; Gastroprotection; Glucocorticoids; Indomethacin

Indexed keywords

CAPSAICIN; CORTICOSTERONE; GLUCOCORTICOID;

ADRENALECTOMY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DESENSITIZATION; GLUCOSE BLOOD LEVEL; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STOMACH EROSION; STOMACH MUCOSA;

ADRENALECTOMY; ANIMALS; BLOOD GLUCOSE; CAPSAICIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; FASTING; GASTRIC MUCOSA; GLUCOCORTICOIDS; INDOMETHACIN; INJECTIONS, SUBCUTANEOUS; MALE; NEURONS, AFFERENT; RATS; RATS, SPRAGUE-DAWLEY; STOMACH DISEASES; TIME FACTORS;

EID: 27744514299     PISSN: 09254692     EISSN: None     Source Type: Journal    
DOI: 10.1163/156856005774423782     Document Type: Article

References (27)

1. Bartho, L., Benko, R., Patacchini, R., et al. (2004). Effects of capsaicin on visceral smooth muscle: a valuable tool for sensory neurotransmitter identification, Eur. J. Pharmacol. 500, 143-157.
2. Chan, O., Chan, S., Inouye, K., et al. (2002). Diabetes impairs hypothalamo-pituitary-adrenal (HPA) responses to hypoglycemia, and insulin treatment normalizes HPA but not epinephrine responses, Diabetes 51, 1681-1689.
3. Ehrlich, K., Sicking, C., Respondek, M., et al. (2004). Interaction of cyclooxygenase isoenzymes, nitric oxide, and afferent neurons in gastric mucosal defence in rats, J. Pharmacol. Exp. Ther. 308, 277-283.
4. Erturk, E., Jaffe, C. A. and Barkan, A. L. (1998). Evaluation of the integrity of the hypothalamic-pituitary-adrenal axis by insulin hypoglycemia test, J. Clin. Endocrinol. Metab. 83, 2350-2354.
5. Esplugues, J. V. and Whittle, B. J. R. (1990). Morphine potentiation of ethanol-induced gastric mucosal damage in the rats: role of local sensory afferent neurons, Gastroenterology 98, 82-89.
6. Filaretova, L. P. (1990). The dependence of the formation of stress stomach ulcers on the function of hypothalamo-hypophyseal-adrenocortical system, Sechenov Physiol. J. USSR 76, 1594-1600.
7. Filaretova, L., Maltcev, N., Bogdanov, A., et al. (1999). Role of gastric microcirculation in the gastroprotection by glucocorticoids released during water-restraint stress in rats, Chin. J. Physiol. 42, 145-152.
8. Filaretova, L. P., Podvigina, T. T., Bagaeva, T. R., et al. (2001). Gastroprotective action of glucocorticoids during the formation and the healing of indomethacin-induced gastric erosions in rats, J. Physiol. 95, 201-208.
9. Filaretova, L. P., Bagaeva, T. R. and Makara, G. B. (2002a). Aggravation of nonsteroidal antiinflammatory drug gastropathy by glucocorticoid deficiency or blockade of glucocorticoid receptor in rats, Life Sci. 71, 2457-2468.
10. Filaretova, L. P., Bagaeva, T. R. and Podvigina, T. T. (2002b). Role of endogenous glucocorticoids in the healing of gastric erosions and chronic gastric ulcers in rats, Inflammopharmacology 10, 401-412.
11. Filaretova, L. P., Filaretov, A. A. and Makara, G. B. (1998). Corticosterone increase inhibits stress-induced gastric erosions in rats, Am. J. Physiol. 274, G1024-G1030.
12. Filaretova, L., Tanaka, A., Miyazawa, T., et al. (2002c). Mechanisms by which endogenous glucocorticoids protects against indomethacin-induced gastric injury in rats, Am. J. Physiol. 83, G1082-G1089.
13. Filaretova, L., Komoike, Y., Tanaka, A., et al. (2002d). COX-2 inhibitor induces gastric mucosal damage in adrenalectomized, Inflammopharmacology 10, 413-422.
14. Holzer, P. (1998). Neural emergency system in the stomach, Gastroenterology 114, 823-839.
15. Holzer, P. (2004). TRPV1 and the gut: from a tasty receptor for a painful vanilloid to a key player in hyperalgesia, Eur. J. Pharmacol. 500, 231-241.
16. Holzer, P., Livingston, E. H. and Guth, P. H. (1991). Sensory neurons signal for an increase in rat gastric mucosal blood flow in the face of pending acid injury, Gastroenterology 101, 416-423.
17. Jacob, M., Bjarnason, I., Rafi, S., et al. (2001). A study of the effect of indomethacin on liver mitochondria from rats, mice and humans, Aliment. Pharmacol. Ther. 15, 1837-1842.
18. Kato, S., Aihara, E., Nakamura, A., et al. (2003). Expression of vanilloid receptors in rat gastric epithelial cellular protection, Biochem. Pharmacol. 66, 1115-1121.
19. Mobbs, C. V., Kow, L.-M. and Yang, X.-J. (2001). Brain glucose-sensing mechanisms: ubiquitous silencing by aglycemia vs. hypothalamic neuroendocrine responses, Am. J. Physiol. 281, E649-E654.
20. Szolcsanyi, J. and Bartho, L. (2001). Capsaicin-sensitive afferents and their role in gastroprotection:update, J. Physiol. 95, 181-188.
21. Takeuchi, K., Nishiwaki, H., Okada, M., et al. (1989). Bilateral adrenalectomy worsens gastric mucosal lesions induced by indomethacin in the rat. Role of enhanced gastric motility, Gastroenterology 97, 284-293.
22. Takeuchi, K., Tanaka, A., Suzuki, K., et al. (2001). Gastrointestinal sparing anti-inflammatory drugs - effects on ulcerogenic and healing responses, Curr. Pharm. Design 7, 49-69.
23. Takeuchi, K., Kato, S., Takeeda, M., et al. (2003). Facilitation by endogenous prostaglandins of capsaicin-induced protection in rodent through EP2 and Ip receptors, J. Pharmacol. Exp. Ther. 304, 1055-1062.
24. Wallace, J. L. (1997). Nonsteroidal anti-inflammatory drugs and gastroenteropathy: the second hundred years, Gastroenterology 112: 1000-1016.
25. Wallace, J. L. and Del Soldato, P. (2003). The therapeutic potential of NO-NSAIDs, Fundam. Clin. Pharmacol. 17, 11-20.
26. Whittle, B. J. R., Lopez-Belmonte, J. and Moncada, S. (1990). Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rats, Br. J. Pharmacol. 99, 606-611.
27. Zhou, X.-F., Jhamandas, K. H. and Livett, B. G. (1990). Capsaicin-sensitive nerves are required for glucostasis but not for catecholamine output during hypoglycemia in rats, Am. J. Physiol. 258, E212-E219.