Corticosterone increase inhibits stress-induced gastric erosions in rats

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 274, Issue 6 37-6, 1998, Pages

  Filaretova, L P ^a   Filaretov, A A ^a   Makara, G B ^b,c  

^a PAVLOV INSTITUTE OF PHYSIOLOGY   (Russian Federation)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Gastric erosion; Glucocorticoids; Hypothalamic lesion; RU 38486

Indexed keywords

CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; MIFEPRISTONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CORTICOSTERONE BLOOD LEVEL; CORTICOSTERONE RELEASE; FLUOROMETRY; HYPOTHALAMUS LESION; MALE; NONHUMAN; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; STATISTICAL ANALYSIS; STOMACH EROSION; STRESS; ULCEROGENESIS;

EID: 0031744419     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1998.274.6.g1024     Document Type: Article

References (48)

1. Alexandrova, M. Stress induced tyrosine aminotransferase activity via glucocorticoid receptor. Horm. Metab. Res. 26: 97-99, 1994.
2. Aou, S., J. Ma, T. Hori, and N. Tashiro. Hypothalamic linkage in stress-induced hypocalcemia, gastric damage, and emotional behavior in rats. Am. J. Physiol. 267 (Regulatory Integrative Comp. Physiol. 36): R38-R43, 1994.
3. Bakker, H. K., and R. Murison. Plasma corticosterone and restraint induced gastric pathology: age-related differences after administration of corticotropin releasing factor. Life Sci. 45: 907-916, 1989.
4. Balashov, Y. G. Fluorometric micromethod for determination of corticosteroids: comparison of three methods. Sechenov Physiol. J. USSR 76: 280-283, 1990.
5. Black, H. E. The effects of steroids upon the gastrointestinal tract. Taxicol. Pathol. 16: 213-222, 1988.
6. Bonfils, S., J.-P. Hardouin, G. Rossi, G. Richier, and A. Lambling. Les ulceration gastriques provoquees chez le rat blanc par la cortisone et la delta-cortisone. Arch. Mal. App. Digest. 46: 385-399, 1957.
7. Bruhn, T. O., P. M. Plotsky, and W. Vale. Effect of paraventricular lesions on corticotropin-releasing factor (CRF)-like immunoreactivity in the stalk-median eminence: studies on the adrenocorticotropin response to ether stress and exogenous CRF. Endocrinology 111: 1418-1420, 1984.
8. Filaretova, L. P. Pituitary-adrenocortical system, and hemorrhage in stomach. In: Mechanisms of Regulation of Physiological Function, edited by V. T. Schuvaev. Leningrad, 1988, p. 70-71.
9. Filaretova, L. P. The dependence of the formation of stress stomach ulcers on the function of the hypothalamo-hypophyseal-adrenocortical system. Sechenov Physiol. J. USSR 76: 1594-1600, 1990.
10. Filaretova, L. P. Stress-induced gastric ulceration: antiulcerogenic action of glucocorticoids (Abstract). Proc. Cong. Gastroenterol. 10th Los Angeles 1994, p. 1972.
11. Filaretova, L. P., and A. A. Filaretov. The effect of large corticosteroid doses on stomach ulceration: a new hypothesis. Sechenov Physiol. J. USSR 78: 77-83, 1992.
12. Filaretova, L. P., D. I. Tokarev, Y. U. Levkovich, N. A. Maltcev, and A. A. Filaretov. The circadian rhythm of stress-induced gastric ulceration in rats. Sechenov Physiol. J. USSR 79: 60-66, 1993.
13. Gray, S. J., A. Benson, and R. W. Reifenstein. Chronic stress and peptic ulcer. I. Effect of corticotropin (ACTH) and corticosterone on gastric secretion. JAMA 147: 1529-1537, 1951.
14. Gunion, M. W., G. L. Kauffman, and Y. Taché. Intrahypothalamic corticotropin-releasing factor elevates gastric bicarbonate and inhibits stress ulcers in rats. Am. J. Physiol. 258 (Gastrointest. Liver Physiol. 21): G152-G157, 1990.
15. Guth, P. H. Current concept in gastric microcirculatory pathophysiology. Yale J. Biol. Med. 65: 677-688, 1992.
16. Hernandez, D. E. Neuroendocrine mechanisms of stress ulceration: focus on thyrotropin-releasing hormone. Life Sci. 39: 279-296, 1986.
17. Hernandez, D. E., J. W. Adcock, C. B. Nemeroff, and A. J. Prange. The role of adrenal gland in cytoprotection against stress-induced gastric ulcers in rats. J. Neurosci. Res. 11: 193-201, 1984.
18. Hernandez, D. E., and G. B. Glavin. Neurobiology of Stress Ulcers. New York: New York Academy of Sciences, 1990.
19. Ivanov, K. P., M. K. Kalinina, and Y. Levcovich. Blood flow velocity in capillaries of brain and muscles and its physiological significance. Microvasc. Res. 22: 143-155, 1981.
20. Kovács, K., J. Z. Kiss, and G. B. Makara. Glucocorticoid implants around the hypothalamic paraventricular nucleus prevent the increase of corticotropin-releasing factor and arginine vasopressin immunostaining induced by adrenalectomy. Neuroendocrinology 44: 229-234, 1986.
21. Kovács, K. J., and E. Mezey. Dexamethasone inhibits corticotropin-releasing factor gene expression in the rat paraventricular nucleus. Neuroendocrinology 46: 365-368, 1987.
22. Lee, Y. H., and K. W. Mollison. Studies on restraint-induced ulcer in rats. In: Experimental Ulcer, edited by T. Gheorghiu. Cologne, Germany: Witzstrock, 1975, p. 52-57.
23. Lenz, H. J. Regulation of duodenal bicarbonate secretion during stress by corticotropin-releasing factor and endorphin. Proc. Natl. Acad. Sci. USA 86: 1417-1420, 1989.
24. Makara, G. B., E. Stark, G. Kapocs, and F. A. Antoni. Long-term effects of hypothalamic paraventricular lesion on CRF content and stimulated ACTH secretion. Am. J. Physiol. 250 (Endocrinol. Metab. 13): E319-E324, 1986.
25. Menguy, R. Effects of restraint stress on gastric secretion in the rat. Am. J. Dig. Dis. 5: 911-916, 1960.
26. Mergl, Z., E. Stokum, and Z. Acs. Radioimmunological determination of hydrocortisone and corticosterone in unextracted plasma. In: Proceedings of International Symposium Physiology of Pituitary-Adrenocortical System, edited by A. A. Filaretov. Leningrad, p. 24, 1990.
27. Moguilewski, M., and D. Philibert. RU 38486: potent antiglucocorticoid activity correlated with strong binding to cytosolic glucocorticoid receptor followed by an impaired activation. J. Steroid Biochem. 20: 271-276, 1984.
28. Munck, A., P. M. Guyre, and N. J. Holbrook. Physiological functions of glucocorticoids in stress and their relation to pharmacological actions. Endocr. Rev. 5: 25-44, 1984.
29. Murison, R., and J. B. Overmier. Adrenocortical activity and disease, with reference to gastric pathology in animals. In: Neurobiological Approaches to Human Disease, edited by D. Hellhammer, I. Florin, and H. Weiner. Toronto, Canada: Hans Huber, 1988, p. 335-343.
30. Murison, R., J. B. Overmier, D. H. Hellhammer, and M. Carmona. Hypothalamo-pituitary-adrenal manipulations and stress ulcerations in rats. Psychoneuroendocrinology 14: 331-338, 1989.
31. Murphy, H. M., C. H. Wideman, and T. S. Brown. Plasma corticosterone levels and ulcer formation in rats with hippocampal lesions. Neuroendocrinology 28: 123-130, 1979.
32. Nicoloff, D. M., E. D. Peter, A. S. Leonard, and O. H. Wangensteen. Catecholamines in ulcer provocation: their possible role in stress ulcer formation. JAMA 191: 383-385, 1965.
33. Palkovits, M., K. J. Kovacs, and G. B. Makara. Corticotropin-releasing hormone-containing neurons in the hypothalamo-hypophyseal system in rats six weeks after bilateral lesions of the paraventricular nucleus. Neuroscience 54: 274-278, 1991.
34. Perretti, M., K. G. Mugridge, J. L. Wallace, and L. Parente. Reduction of aspirin-induced gastric damage in rats by interleukin-1 beta: possible involvement of endogenous corticosteroids. J. Pharmacol. Exp. Ther. 261: 1238-1247, 1992.
35. Redei, E., W. P. Paré, F. Aird, and J. Kluczynski. Strain differences in hypothalamic-pituitary-adrenal activity and stress ulcer. Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R353-R360, 1994.
36. Renaud, S. Improved restraint-technique for producing stress and cardiac necrosis in rats. J. Appl. Physiol. 14: 868-869, 1959.
37. Sakaguchi, T., and M. Ohtake. Inhibition of gastric motility induced by activation of the hypothalamic paraventricular nucleus. Brain Res. 335: 365-367, 1985.
38. Sandweiss, D. J. Effects adrenocorticotropic hormone (ACTH) and of cortisone on peptic ulcer. I. Clinical review. Gastroenterology 27: 604-616, 1954.
39. Szabo, S., G. T. Callagher, H. C. Horner, P. W. Frankel, R. H. Underwood, S. J. Konturek, T. Brzozowski, and J. S. Trier. Role of the adrenal cortex in gastric mucosal protection by prostaglandins, sulfhydryls, and cimetidine in the rat. Gastroenterology 85: 1384-1390, 1983.
40. Taché, Y., Y. Goto, M. Gunion, J. Rivier, and H. Debas. Inhibition of gastric acid secretion in rats and in dogs by corticotropin-releasing factor. Gastroenterology 86: 281-286, 1984.
41. Taché, Y., H. Yang, and H. Kaneko. Caudal raphe-dorsal vagal complex peptidergic projections: role in gastric vagal control. Peptides 16: 431-435, 1995.
42. Takeuchi, K., H. Nishiwaki, M. Okada, H. Niida, and S. Okabe. Bilateral adrenalectomy worsens gastric mucosal lesions induced by indomethacin in the rat. Role of enhanced gastric motility. Gastroenterology 97: 284-293, 1989.
43. Tempel, D. L., B. S. McEwen, and S. F. Leibowitz. Adrenal steroid receptors in the PVN: studies with steroid antagonists in relation to macronutrient intake. Neuroendocrinology 57: 1106-1113, 1993.
44. Toth, T. An unusual stress-induced gastric lesion. Acta Physiol. Hung. 73: 203-206, 1989.
45. Vaughan, J., C. Donaldson, J. Bittencourt, M. H. Perrin, K. Lewis, S. Button, R. Chan, A. V. Turnbull, D. Lovejoy, and C. Rivier. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor. Nature 378: 287-292, 1995.
46. Weiss, J. M. Effects of coping behavior in different warning signal conditions on stress pathology in rats. J. Comp. Physiol. Psychol. 77: 1-13, 1971.
47. Weusten, B. L., J. W. Jacobs, and J. M. Bijlsma. Corticosteroid pulse therapy in active rheumatoid arthritis. Semin. Arthritis Rheum. 23: 183-192, 1993.
48. Yang, H., S. V. Wu, T. Ishikawa, and Y. Taché. Cold exposure elevates thyrotropin-releasing hormone gene expression in medullary raphe nuclei: relationship with vagally mediated gastric erosions. Neuroscience 61: 655-663, 1994.