The protective effect of lactose on lyophilization of CNK-20402

AAPS PharmSciTech

Volumn 6, Issue 1, 2005, Pages

  Lee, Yung Chi ^a   Nelson, Jared ^a   Sueda, Katsuhiko ^a   Seibert, Donna ^a   Hsieh, Wen Yaw ^a   Braxton, Bryan ^a  

^a PFIZER INC   (United States)

Author keywords

Lactose; Lyophilization; Mannitol; Solubility; Stability; Water vapor sorption

Indexed keywords

CNK 20193; CNK 20402; DRUG RESIDUE; EXCIPIENT; GLYCINE; LACTOSE; MANNITOL; NEW DRUG; POVIDONE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BINDING COMPETITION; CHEMICAL INTERACTION; CHEMICAL PROCEDURES; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CRYSTALLIZATION; DRUG FORMULATION; DRUG IMPURITY; DRUG SCREENING; DRUG STABILITY; DRUG STORAGE; EXPERIMENTAL DESIGN; FEASIBILITY STUDY; FREEZE DRYING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMIDITY; HYDROPHILICITY; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; POWDER DIFFRACTION; PRODUCT RECOVERY; STATISTICAL ANALYSIS; TITRIMETRY; WATER VAPOR; X RAY DIFFRACTION;

CHEMISTRY, PHARMACEUTICAL; DRUG STABILITY; DRUGS, INVESTIGATIONAL; EXCIPIENTS; FREEZE DRYING; LACTOSE;

EID: 27744492676     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/pt060109     Document Type: Article

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