메뉴 건너뛰기




Volumn 17, Issue 8, 2003, Pages 1573-1582

Clonality profile in relapsed precursor-B-ALL children by GeneScan and sequencing analyses. Consequences on minimal residual disease monitoring

Author keywords

GeneScan analysis; lg TCR gene rearrangements; MRD; Precursor B ALL; Relapse

Indexed keywords

IMMUNOGLOBULIN; T LYMPHOCYTE RECEPTOR;

EID: 0043028676     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2403008     Document Type: Article
Times cited : (45)

References (47)
  • 2
    • 17744369251 scopus 로고    scopus 로고
    • Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) acute lymphoblastic leukemia studies, 1982-1995
    • Conter V, Anco M, Valsecchi MC, Basso C, Biondi A, Madon E et al. Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) acute lymphoblastic leukemia studies, 1982-1995. Leukemia 2000; 14: 2196-2204.
    • (2000) Leukemia , vol.14 , pp. 2196-2204
    • Conter, V.1    Anco, M.2    Valsecchi, M.C.3    Basso, C.4    Biondi, A.5    Madon, E.6
  • 4
    • 0032572924 scopus 로고    scopus 로고
    • Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia
    • European Organization for Research and Treatment of Cancer, Childhood Leukemia Cooperative Group
    • Cave H, van der Werff ten Bosch J, Suciu S, Guidal C, Waterkeyn C, Otten J et al. Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia. European Organization for Research and Treatment of Cancer, Childhood Leukemia Cooperative Group. N Engl J Med 1998; 339: 591-598.
    • (1998) N. Engl. J. Med. , vol.339 , pp. 591-598
    • Cave, H.1    van der Werff ten Bosch, J.2    Suciu, S.3    Guidal, C.4    Waterkeyn, C.5    Otten, J.6
  • 5
    • 0034054159 scopus 로고    scopus 로고
    • New definition of remission in childhood acute lymphoblastic leukemia
    • Pui CH, Campana D. New definition of remission in childhood acute lymphoblastic leukemia. Leukemia 2000; 14: 783-785.
    • (2000) Leukemia , vol.14 , pp. 783-785
    • Pui, C.H.1    Campana, D.2
  • 6
    • 0036550728 scopus 로고    scopus 로고
    • Late relapse of childhood acute lymphoblastic leukemia and PCR-monitoring of minimal residual disease: How much time can elapse between 'molecular' and clinical relapse?
    • ELT19. Available from URL:
    • Arico' M, Germano G, del Giudice L, Ziino O, Locatelli F, Basso G. Late relapse of childhood acute lymphoblastic leukemia and PCR-monitoring of minimal residual disease: how much time can elapse between 'molecular' and clinical relapse? Haematologica 2002; 87: ELT19. Available from URL: http://www.haematologica.it/e-letters/2002_04/19.htm
    • (2002) Haematologica , vol.87
    • Arico', M.1    Germano, G.2    del Giudice, L.3    Ziino, O.4    Locatelli, F.5    Basso, G.6
  • 7
    • 0031760453 scopus 로고    scopus 로고
    • Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes
    • Pongers-Willemse MJ, Verhagen OJ, Tibbe GJ, Wijkhuijs AJ, de Haas V, Roovers E et al. Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes. Leukemia 1998; 12: 2006-2014.
    • (1998) Leukemia , vol.12 , pp. 2006-2014
    • Pongers-Willemse, M.J.1    Verhagen, O.J.2    Tibbe, G.J.3    Wijkhuijs, A.J.4    de Haas, V.5    Roovers, E.6
  • 8
    • 0033894921 scopus 로고    scopus 로고
    • Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia
    • Verhagen OJ, Willemse MJ, Breunis WB, Wijkhuijs AJ, Jacobs DC, Joosten SA et al. Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia. Leukemia 2000; 14: 1426-1435.
    • (2000) Leukemia , vol.14 , pp. 1426-1435
    • Verhagen, O.J.1    Willemse, M.J.2    Breunis, W.B.3    Wijkhuijs, A.J.4    Jacobs, D.C.5    Joosten, S.A.6
  • 9
    • 0032919213 scopus 로고    scopus 로고
    • Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets: Report of the BIOMED-1 CONCERTED ACTION: Investigation of minimal residual disease in acute leukemia
    • Pongers-Willemse MJ, Seriu T, Stolz F, d'Aniello E, Gameiro P, Pisa P et al. Primers and protocols for standardized detection of minimal residual disease in acute lymphoblastic leukemia using immunoglobulin and T cell receptor gene rearrangements and TAL1 deletions as PCR targets: report of the BIOMED-1 CONCERTED ACTION: investigation of minimal residual disease in acute leukemia. Leukemia 1999; 13: 110-118.
    • (1999) Leukemia , vol.13 , pp. 110-118
    • Pongers-Willemse, M.J.1    Seriu, T.2    Stolz, F.3    d'Aniello, E.4    Gameiro, P.5    Pisa, P.6
  • 10
    • 0023720148 scopus 로고
    • T-cell antigen receptor genes and T-cell recognition
    • Davis MM, Bjorkman PJ. T-cell antigen receptor genes and T-cell recognition. Nature 1988; 334: 395-402.
    • (1988) Nature , vol.334 , pp. 395-402
    • Davis, M.M.1    Bjorkman, P.J.2
  • 12
    • 0032996684 scopus 로고    scopus 로고
    • Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias: Alternative PCR targets for detection of minimal residual disease
    • Szczepanski T, Beishuizen A, Pongers-Willemse MJ, Hahlen K, Van Wering ER, Wijkhuijs AJ et al. Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias: alternative PCR targets for detection of minimal residual disease. Leukemia 1999; 13: 196-205.
    • (1999) Leukemia , vol.13 , pp. 196-205
    • Szczepanski, T.1    Beishuizen, A.2    Pongers-Willemse, M.J.3    Hahlen, K.4    Van Wering, E.R.5    Wijkhuijs, A.J.6
  • 13
    • 0031452746 scopus 로고    scopus 로고
    • Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations
    • Langerak AW, Szczepanski T, van der Burg M, Wolvers-Tettero IL, van Dongen JJ. Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations. Leukemia 1997; 11: 2192-2199.
    • (1997) Leukemia , vol.11 , pp. 2192-2199
    • Langerak, A.W.1    Szczepanski, T.2    van der Burg, M.3    Wolvers-Tettero, I.L.4    van Dongen, J.J.5
  • 14
    • 0027268304 scopus 로고
    • Differences in immunoglobulin heavy chain gene rearrangement patterns between bone marrow and blood samples in childhood precursor B-acute lymphoblastic leukemia at diagnosis
    • Beishuizen A, Verhoeven MA, Hahlen K, van Wering ER, van Dongen JJ. Differences in immunoglobulin heavy chain gene rearrangement patterns between bone marrow and blood samples in childhood precursor B-acute lymphoblastic leukemia at diagnosis. Leukemia 1993; 7: 60-63.
    • (1993) Leukemia , vol.7 , pp. 60-63
    • Beishuizen, A.1    Verhoeven, M.A.2    Hahlen, K.3    van Wering, E.R.4    van Dongen, J.J.5
  • 15
    • 0027489873 scopus 로고
    • Southern blot patterns, frequencies, and Junctional diversity of T-cell receptor-delta gene rearrangements in acute lymphoblastic leukemia
    • Breit TM, Wolvers-Tettero IL, Beishuizen A, Verhoeven MA, van Wering ER, van Dongen JJ. Southern blot patterns, frequencies, and Junctional diversity of T-cell receptor-delta gene rearrangements in acute lymphoblastic leukemia. Blood 1993; 82: 3063-3074.
    • (1993) Blood , vol.82 , pp. 3063-3074
    • Breit, T.M.1    Wolvers-Tettero, I.L.2    Beishuizen, A.3    Verhoeven, M.A.4    van Wering, E.R.5    van Dongen, J.J.6
  • 16
    • 0027182995 scopus 로고
    • Clonal selection in acute lymphoblastic leukaemia demonstrated by polymerase chain reaction analysis of immunoglobulin heavy chain and T-cell receptor delta chain rearrangements
    • Langlands K, Craig JI, Anthony RS, Parker AC. Clonal selection in acute lymphoblastic leukaemia demonstrated by polymerase chain reaction analysis of immunoglobulin heavy chain and T-cell receptor delta chain rearrangements. Leukemia 1993; 7: 1066-1070.
    • (1993) Leukemia , vol.7 , pp. 1066-1070
    • Langlands, K.1    Craig, J.I.2    Anthony, R.S.3    Parker, A.C.4
  • 17
    • 0036530196 scopus 로고    scopus 로고
    • Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B-ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual disease
    • Szczepanski T, Willemse MJ, Brinkhof B, van Wering ER, van der Burg M, van Dongen JJ. Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B-ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual disease. Blood 2002; 99: 2315-2323.
    • (2002) Blood , vol.99 , pp. 2315-2323
    • Szczepanski, T.1    Willemse, M.J.2    Brinkhof, B.3    van Wering, E.R.4    van der Burg, M.5    van Dongen, J.J.6
  • 18
    • 0031974403 scopus 로고    scopus 로고
    • Automated high-resolution polymerase chain reaction fragment analysis a methods for detecting T-cell receptor gamma-chain gene rearrangements in lymphoproliferative diseases
    • Simon M, Kind P, Kaudewitz P, Krokowski M, Graf A, Prinz J et al. Automated high-resolution polymerase chain reaction fragment analysis. a methods for detecting T-cell receptor gamma-chain gene rearrangements in lymphoproliferative diseases. Am J Pathol 1998; 152: 29-33.
    • (1998) Am. J. Pathol. , vol.152 , pp. 29-33
    • Simon, M.1    Kind, P.2    Kaudewitz, P.3    Krokowski, M.4    Graf, A.5    Prinz, J.6
  • 19
    • 0033058479 scopus 로고    scopus 로고
    • Clonal T-cell receptor gamma-chain gene rearrangement by PCR-based GeneScan analysis in advanced cutaneous T-cell lymphoma: A critical evaluation
    • Dippel E, Assaf C, Hummel M, Schrag HJ, Stein H, Goerdt S et al. Clonal T-cell receptor gamma-chain gene rearrangement by PCR-based GeneScan analysis in advanced cutaneous T-cell lymphoma: a critical evaluation. J Pathol 1999; 188: 146-154.
    • (1999) J. Pathol. , vol.188 , pp. 146-154
    • Dippel, E.1    Assaf, C.2    Hummel, M.3    Schrag, H.J.4    Stein, H.5    Goerdt, S.6
  • 20
    • 0036236273 scopus 로고    scopus 로고
    • A competitive PCR-based method using TCRD, TCRG and IGH rearrangements for rapid detection of patients with high levels of minimal residual disease in acute lymphoblastic leukemia
    • Guidal C, Vilmer E, Grandchamp B, Cave H. A competitive PCR-based method using TCRD, TCRG and IGH rearrangements for rapid detection of patients with high levels of minimal residual disease in acute lymphoblastic leukemia. Leukemia 2002; 16: 762-764.
    • (2002) Leukemia , vol.16 , pp. 762-764
    • Guidal, C.1    Vilmer, E.2    Grandchamp, B.3    Cave, H.4
  • 21
    • 0034918896 scopus 로고    scopus 로고
    • New methodologic approaches for immunophenotyping acute leukemias
    • Basso G, Buldini B, De Zen L, Orfao A. New methodologic approaches for immunophenotyping acute leukemias. Haematologica 2001; 86: 675-692.
    • (2001) Haematologica , vol.86 , pp. 675-692
    • Basso, G.1    Buldini, B.2    De Zen, L.3    Orfao, A.4
  • 22
    • 0026498255 scopus 로고
    • Minimal requirements for the diagnosis, classification, and evaluation of the treatment of childhood acute lymphoblastic leukemia (ALL) in the 'BFM Family' Cooperative Group
    • van der Does-van den Berg A, Bartram CR, Basso G, Benoit YC, Biondi A, Debatin KM et al. Minimal requirements for the diagnosis, classification, and evaluation of the treatment of childhood acute lymphoblastic leukemia (ALL) in the 'BFM Family' Cooperative Group. Med Pediatr Oncol 1992; 20: 497-505.
    • (1992) Med. Pediatr. Oncol. , vol.20 , pp. 497-505
    • van der Does-van den Berg, A.1    Bartram, C.R.2    Basso, G.3    Benoit, Y.C.4    Biondi, A.5    Debatin, K.M.6
  • 23
    • 12944277156 scopus 로고    scopus 로고
    • Quantitative multiparametric immunophenotyping in acute lymphoblastic leukemia: Correlation with specific genotype. I. ETV6/AML1 ALLs identification
    • De Zen L, Orfao A, Cazzaniga G, Masiero L, Cocito MG, Spinelli M et al. Quantitative multiparametric immunophenotyping in acute lymphoblastic leukemia: correlation with specific genotype. I. ETV6/AML1 ALLs identification. Leukemia 2000; 14: 1225-1231.
    • (2000) Leukemia , vol.14 , pp. 1225-1231
    • De Zen, L.1    Orfao, A.2    Cazzaniga, G.3    Masiero, L.4    Cocito, M.G.5    Spinelli, M.6
  • 24
    • 0032147024 scopus 로고    scopus 로고
    • Expression of myeloid markers lacks prognostic impact in children treated for acute lymphoblastic leukemia: Italian experience in AIEOP-ALL 88-91 studies
    • Putti MC, Rondelli R, Cocito MG, Arico M, Sainati L, Conter V et al. Expression of myeloid markers lacks prognostic impact in children treated for acute lymphoblastic leukemia: Italian experience in AIEOP-ALL 88-91 studies. Blood 1998; 92: 795-801.
    • (1998) Blood , vol.92 , pp. 795-801
    • Putti, M.C.1    Rondelli, R.2    Cocito, M.G.3    Arico, M.4    Sainati, L.5    Conter, V.6
  • 25
    • 17344367455 scopus 로고    scopus 로고
    • Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: Implications for selection of PCR targets for detection of minimal residual disease
    • Szczepanski T, Langerak AW, Wolvers-Tettero IL, Ossenkoppele GJ, Verhoef G, Stul M et al. Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children: implications for selection of PCR targets for detection of minimal residual disease. Leukemia 1998; 12: 1081-1088.
    • (1998) Leukemia , vol.12 , pp. 1081-1088
    • Szczepanski, T.1    Langerak, A.W.2    Wolvers-Tettero, I.L.3    Ossenkoppele, G.J.4    Verhoef, G.5    Stul, M.6
  • 26
    • 0036069926 scopus 로고    scopus 로고
    • Clonal T cell receptor gamma-chain gene rearrangement by PCR-based GeneScan analysis in the skin and blood of patients with parapsoriasis and early-stage mycosis fungoides
    • Klemke CD, Dippel E, Dembinski A, Ponitz N, Assaf C, Hummel M et al. Clonal T cell receptor gamma-chain gene rearrangement by PCR-based GeneScan analysis in the skin and blood of patients with parapsoriasis and early-stage mycosis fungoides. J Pathol 2002; 197: 348-354.
    • (2002) J. Pathol. , vol.197 , pp. 348-354
    • Klemke, C.D.1    Dippel, E.2    Dembinski, A.3    Ponitz, N.4    Assaf, C.5    Hummel, M.6
  • 27
    • 0031762061 scopus 로고    scopus 로고
    • Residual disease detection using fluorescent polymerase chain reaction at 20 weeks of therapy predicts clinical outcome in childhood acute lymphoblastic leukemia
    • Evans PA, Short MA, Owen RG, Jack AS, Forsyth PD, Shiach CR et al. Residual disease detection using fluorescent polymerase chain reaction at 20 weeks of therapy predicts clinical outcome in childhood acute lymphoblastic leukemia. J Clin Oncol 1998; 16: 3616-3627.
    • (1998) J. Clin. Oncol. , vol.16 , pp. 3616-3627
    • Evans, P.A.1    Short, M.A.2    Owen, R.G.3    Jack, A.S.4    Forsyth, P.D.5    Shiach, C.R.6
  • 28
    • 0034129711 scopus 로고    scopus 로고
    • Rapid, multifluorescent TCRG Vgamma and Jgamma typing: Application to T cell acute lymphoblastic leukemia and to the detection of minor clonal populations
    • Delabesse E, Burtin ML, Millien C, Madonik A, Arnulf B, Beldjord K et al. Rapid, multifluorescent TCRG Vgamma and Jgamma typing: application to T cell acute lymphoblastic leukemia and to the detection of minor clonal populations. Leukemia 2000; 14: 1143-1152.
    • (2000) Leukemia , vol.14 , pp. 1143-1152
    • Delabesse, E.1    Burtin, M.L.2    Millien, C.3    Madonik, A.4    Arnulf, B.5    Beldjord, K.6
  • 29
    • 0031450244 scopus 로고    scopus 로고
    • Detection of clonality by heteroduplex analysis of amplified junctional region of T-cell receptor gamma in patients with T-cell acute lymphoblastic leukemias
    • Martinelli G, Farabegoli P, Testoni N, Terragna C, Vittone A, Raspadori D et al. Detection of clonality by heteroduplex analysis of amplified junctional region of T-cell receptor gamma in patients with T-cell acute lymphoblastic leukemias. Haematologica 1997; 82: 161-165.
    • (1997) Haematologica , vol.82 , pp. 161-165
    • Martinelli, G.1    Farabegoli, P.2    Testoni, N.3    Terragna, C.4    Vittone, A.5    Raspadori, D.6
  • 30
    • 0028239989 scopus 로고
    • Heteroduplex analysis of T-cell receptor gamma gene rearrangements for diagnosis and monitoring of cutaneous T-cell lymphomas
    • Bottaro M, Berti E, Biondi A, Migone N, Crosti L. Heteroduplex analysis of T-cell receptor gamma gene rearrangements for diagnosis and monitoring of cutaneous T-cell lymphomas. Blood 1994; 83: 3271-3278.
    • (1994) Blood , vol.83 , pp. 3271-3278
    • Bottaro, M.1    Berti, E.2    Biondi, A.3    Migone, N.4    Crosti, L.5
  • 31
    • 0035023288 scopus 로고    scopus 로고
    • Rapid detection of clonality in patients with acute lymphoblastic leukemia
    • Germano G, Songia S, Biondi A, Basso G. Rapid detection of clonality in patients with acute lymphoblastic leukemia. Haematologica 2001; 86: 382-385.
    • (2001) Haematologica , vol.86 , pp. 382-385
    • Germano, G.1    Songia, S.2    Biondi, A.3    Basso, G.4
  • 33
    • 0031790803 scopus 로고    scopus 로고
    • Intensive BFM chemotherapy for childhood ALL: Interim analysis of the AIEOP-ALL 91 study
    • Associazione Italiana Ematologia Oncologia Pediatrica
    • Conter V, Arico M, Valsecchi MG, Rizzari C, Testi A, Miniero R et al. Intensive BFM chemotherapy for childhood ALL: interim analysis of the AIEOP-ALL 91 study. Associazione Italiana Ematologia Oncologia Pediatrica. Haematologica 1998; 83: 791-799.
    • (1998) Haematologica , vol.83 , pp. 791-799
    • Conter, V.1    Arico, M.2    Valsecchi, M.G.3    Rizzari, C.4    Testi, A.5    Miniero, R.6
  • 34
    • 0027952824 scopus 로고
    • A polymerase chain reaction study of the stability of Ig heavy-chain and T-cell receptor delta gene rearrangements between presentation and relapse of childhood B-lineage acute lymphoblastic leukemia
    • Steward CG, Goulden NJ, Katz F, Baines D, Martin PG, Langlands K et al. A polymerase chain reaction study of the stability of Ig heavy-chain and T-cell receptor delta gene rearrangements between presentation and relapse of childhood B-lineage acute lymphoblastic leukemia. Blood 1994; 83: 1355-1362.
    • (1994) Blood , vol.83 , pp. 1355-1362
    • Steward, C.G.1    Goulden, N.J.2    Katz, F.3    Baines, D.4    Martin, P.G.5    Langlands, K.6
  • 35
    • 0028324602 scopus 로고
    • Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: Implications for the detection of minimal residual disease by polymerase chain reaction analysis
    • Beishuizen A, Verhoeven MA, van Wering ER, Hahlen K, Hooijkaas H, van Dongen JJ. Analysis of Ig and T-cell receptor genes in 40 childhood acute lymphoblastic leukemias at diagnosis and subsequent relapse: implications for the detection of minimal residual disease by polymerase chain reaction analysis. Blood 1994; 83: 2238-2247.
    • (1994) Blood , vol.83 , pp. 2238-2247
    • Beishuizen, A.1    Verhoeven, M.A.2    van Wering, E.R.3    Hahlen, K.4    Hooijkaas, H.5    van Dongen, J.J.6
  • 36
    • 0028144470 scopus 로고
    • Characterisation of non-concordance in the T-cel I receptor gamma chain genes at presentation and clinical relapse in acute lymphoblastic leukemia
    • Taylor JJ, Rowe D, Kylefjord H, Chessells J, Katz F, Proctor SJ et al. Characterisation of non-concordance in the T-cel I receptor gamma chain genes at presentation and clinical relapse in acute lymphoblastic leukemia. Leukemia 1994; 8: 60-66.
    • (1994) Leukemia , vol.8 , pp. 60-66
    • Taylor, J.J.1    Rowe, D.2    Kylefjord, H.3    Chessells, J.4    Katz, F.5    Proctor, S.J.6
  • 37
    • 0029049678 scopus 로고
    • Assessment of clonal evolution at Ig/TCR loci in acute lymphoblastic leukaemia by single-strand conformation polymorphism studies and highly resolutive PCR derived methods: Implication for a general strategy of minimal residual disease detection
    • Baruchel A, Cayuela JM, MacIntyre E, Berger R, Sigaux F. Assessment of clonal evolution at Ig/TCR loci in acute lymphoblastic leukaemia by single-strand conformation polymorphism studies and highly resolutive PCR derived methods: implication for a general strategy of minimal residual disease detection. Br J Haematol 1995; 90: 85-93.
    • (1995) Br. J. Haematol. , vol.90 , pp. 85-93
    • Baruchel, A.1    Cayuela, J.M.2    MacIntyre, E.3    Berger, R.4    Sigaux, F.5
  • 38
    • 0032817836 scopus 로고    scopus 로고
    • Clonal evolution as judged by immunoglobulin heavy chain gene rearrangements in relapsing precursor-B acute lymphoblastic leukemia
    • Rosenquist R, Thunberg U, Li AH, Forestier E, Lonnerholm G, Lindh J et al. Clonal evolution as judged by immunoglobulin heavy chain gene rearrangements in relapsing precursor-B acute lymphoblastic leukemia. Eur J Haematol 1999; 63: 171-179.
    • (1999) Eur. J. Haematol. , vol.63 , pp. 171-179
    • Rosenquist, R.1    Thunberg, U.2    Li, A.H.3    Forestier, E.4    Lonnerholm, G.5    Lindh, J.6
  • 39
    • 0034772490 scopus 로고    scopus 로고
    • Detailed clonality analysis of relapsing precursor B acute lymphoblastic leukemia: Implications for minimal residual disease detection
    • Li AH, Rosenquist R, Forestier E, Lindh J, Roos G. Detailed clonality analysis of relapsing precursor B acute lymphoblastic leukemia: implications for minimal residual disease detection. Leukemia Res 2001; 25: 1033-1045.
    • (2001) Leukemia Res. , vol.25 , pp. 1033-1045
    • Li, A.H.1    Rosenquist, R.2    Forestier, E.3    Lindh, J.4    Roos, G.5
  • 41
    • 0033001725 scopus 로고    scopus 로고
    • Clonal stability in children with acute lymphoblastic leukemia (ALL) who relapsed five or more years after diagnosis
    • Lo Nigro L, Cazzaniga G, Di Cataldo A, Pannunzio A, D'Aniello E, Masera G et al. Clonal stability in children with acute lymphoblastic leukemia (ALL) who relapsed five or more years after diagnosis. Leukemia 1999; 13: 190-195.
    • (1999) Leukemia , vol.13 , pp. 190-195
    • Lo Nigro, L.1    Cazzaniga, G.2    Di Cataldo, A.3    Pannunzio, A.4    D'Aniello, E.5    Masera, G.6
  • 42
    • 0032715344 scopus 로고    scopus 로고
    • Molecular assessment of clonality in a pre-B ALL unusually relapsing as a mature-B ALL
    • Balduzzi A, Corral L, Gaipa G, Germano G, Giudici G, Cantu'-Rajnoldi A et al. Molecular assessment of clonality in a pre-B ALL unusually relapsing as a mature-B ALL. Leukemia 1999; 13: 2114-2116.
    • (1999) Leukemia , vol.13 , pp. 2114-2116
    • Balduzzi, A.1    Corral, L.2    Gaipa, G.3    Germano, G.4    Giudici, G.5    Cantu'-Rajnoldi, A.6
  • 43
    • 0034045618 scopus 로고    scopus 로고
    • Detection of clonal T cell populations by high resolution PCR using fluorescently labelled nucleotides; evaluation using conventional LIS-SSCP
    • Wickham CL, Lynas C, Ellard S. Detection of clonal T cell populations by high resolution PCR using fluorescently labelled nucleotides; evaluation using conventional LIS-SSCP. Mol Pathol 2000; 53: 150-154.
    • (2000) Mol. Pathol. , vol.53 , pp. 150-154
    • Wickham, C.L.1    Lynas, C.2    Ellard, S.3
  • 44
    • 0036114311 scopus 로고    scopus 로고
    • Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCR
    • van der Velden VH, Willemse MJ, van der Schoot CE, Hahlen K, van Wering ER, van Dongen JJ. Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCR. Leukemia 2002; 16: 928-936.
    • (2002) Leukemia , vol.16 , pp. 928-936
    • van der Velden, V.H.1    Willemse, M.J.2    van der Schoot, C.E.3    Hahlen, K.4    van Wering, E.R.5    van Dongen, J.J.6
  • 45
    • 0036051771 scopus 로고    scopus 로고
    • T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis
    • van der Velden VH, Wijkhuijs JM, Jacobs DC, van Wering ER, van Dongen JJ. T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis. Leukemia 2002; 16: 1372-1380.
    • (2002) Leukemia , vol.16 , pp. 1372-1380
    • van der Velden, V.H.1    Wijkhuijs, J.M.2    Jacobs, D.C.3    van Wering, E.R.4    van Dongen, J.J.5
  • 46
    • 0033763375 scopus 로고    scopus 로고
    • Use of molecular techniques to confirm true re-emergence of the original clone and to track minimal residual disease in a case of late extramedullary relapse of childhood acute lymphoblastic leukemia
    • Valetto A, Anselmi G, Scuderi F, Lanciotti M, Chiesa V, Dini G. Use of molecular techniques to confirm true re-emergence of the original clone and to track minimal residual disease in a case of late extramedullary relapse of childhood acute lymphoblastic leukemia. Haematologica 2000; 85: 1102-1103.
    • (2000) Haematologica , vol.85 , pp. 1102-1103
    • Valetto, A.1    Anselmi, G.2    Scuderi, F.3    Lanciotti, M.4    Chiesa, V.5    Dini, G.6
  • 47
    • 0035437159 scopus 로고    scopus 로고
    • Origins of 'late' relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes
    • Ford AM, Fasching K, Panzer-Grumayer ER, Koenig M, Haas OA, Greaves MF. Origins of 'late' relapse in childhood acute lymphoblastic leukemia with TEL-AML1 fusion genes. Blood 2001; 98: 558-564.
    • (2001) Blood , vol.98 , pp. 558-564
    • Ford, A.M.1    Fasching, K.2    Panzer-Grumayer, E.R.3    Koenig, M.4    Haas, O.A.5    Greaves, M.F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.