Childhood leukaemia

BMJ

Volumn 324, Issue 7332, 2002, Pages 283-287

  Greaves, Mel ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; CANCER RISK; CELL DIFFERENTIATION; CHILD; CHILDHOOD LEUKEMIA; CHROMOSOME ABERRATION; CHROMOSOME TRANSLOCATION; FUSION GENE; GENE MUTATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; LEUKEMIA CELL; PRIORITY JOURNAL; PROGNOSIS; REVIEW; ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOCYTIC LEUKEMIA; CHROMOSOME 12; CHROMOSOME 21; GENE TRANSLOCATION; GENETIC MARKER; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; INFANT; INFECTION; PHILADELPHIA 1 CHROMOSOME; PRESCHOOL CHILD; TWINS;

ONCOPROTEIN;

CHILD; CHILD, PRESCHOOL; CHROMOSOMES, HUMAN, PAIR 12; CHROMOSOMES, HUMAN, PAIR 21; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; INFECTION; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; LEUKEMIA, MYELOCYTIC, ACUTE; ONCOGENE PROTEINS, FUSION; PHILADELPHIA CHROMOSOME; PROGNOSIS; TRANSLOCATION, GENETIC; TWIN STUDIES;

EID: 0037006217     PISSN: 09598138     EISSN: 14685833     Source Type: Journal    
DOI: 10.1136/bmj.324.7332.283     Document Type: Article

References (28)

1. Rowley JD. The critical role of chromosome translocations in human leukemias. Annu Rev Genet 1998; 32: 495–519.
2. Kersey JH. Fifty years of studies of the biology and therapy of childhood leukemia. Blood 1997; 90: 4243–4251.
3. Greaves M. Molecular genetics, natural history and the demise of childhood leukaemia. Eur J Cancer 1999; 35: 173–185.
4. Greaves M. Cancer. The evolutionary legacy. Oxford: Oxford University Press, 2000.
5. Ford AM, Ridge SA, Cabrera ME, Mahmoud H, Steel CM, Chan LC, et al. In utero rearrangements in the trithorax-related oncogene in infant leukaemias. Nature 1993; 363: 358–360.
6. Wiemels JL, Ford AM, Van Wering ER, Postma A, Greaves M. Protracted and variable latency of acute lymphoblastic leukemia after TEL-AML1 gene fusion in utero. Blood 1999; 94: 1057–1062.
7. Gale KB, Ford AM, Repp R, Borkhardt A, Keller C, Eden OB, et al. Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. Proc Natl Acad Sci USA 1997; 94: 13950–13954.
8. Wiemels JL, Cazzaniga G, Daniotti M, Eden OB, Addison GM, Masera G, et al. Prenatal origin of acute lymphoblastic leukaemia in children. Lancet 1999; 354: 1499–1503.
9. UK Childhood Cancer Study Investigators. The United Kingdom childhood cancer study: objectives, materials and methods. Br J Cancer 2000; 82: 1073–1102.
10. UK Childhood Cancer Study Investigators. Childhood cancer and residential proximity to power lines. Br J Cancer 2000; 83: 1573–1580.
11. Kinlen LJ. Epidemiological evidence for an infective basis in childhood leukaemia. Br J Cancer 1995; 71: 1–5.
12. Greaves MF. Aetiology of acute leukaemia. Lancet 1997; 349: 344–349.
13. Wills-Karp M, Santeliz J, Karp CL. The germless theory of allergic disease: revisiting the hygiene hypothesis. Nat Rev 2001; 1: 69–75.
14. Dockerty JD, Draper G, Vincent T, Rowan SD, Bunch KJ. Case-control study of parental age, parity and socioeconomic level in relation to childhood cancers. Int J Epidemiol (in press).
15. Auvinen A, Hakulinen T, Groves F. Haemophilus influenzae type B vaccination and risk of childhood leukaemia in a vaccine trial in Finland. Br J Cancer 2000; 83: 956–958.
16. Alexander FE, Patheal SL, Biondi A, Brandalise S, Cabrera M-E, Chan LC, et al. Transplacental chemical exposure and risk of infant leukemia with MLL gene fusion. Cancer Res 2001; 61: 2542–2546.
17. Wiemels JL, Pagnamenta A, Taylor GM, Eden OB, Alexander FE, Greaves MF, et al. A lack of a functional NAD(P)H:quinone oxidoreductase allele is selectively associated with pediatric leukemias that have MLL fusions. Cancer Res 1999; 59: 4095–4099.
18. Taylor GM, Dearden S, Payne N, Ayres M, Gokhale DA, Birch JM, et al. Evidence that an HLA-DQA1-DQB1 haplotype influences susceptibility to childhood common acute lymphoblastic leukaemia in males provides further support for an infection-related aetiology. Br J Cancer 1998; 78: 561–565.
19. Wiemels JL, Smith RN, Taylor GM, Eden OB, Alexander FE, Greaves MF, et al. Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemia. Proc Natl Acad Sci USA 2001; 98: 4004–4009.
20. Thompson JR, FitzGerald P, Willoughby MLN, Armstrong BK. Maternal folate supplementation in pregnancy and protection against common acute lymphoblastic leukaemia in childhood: a case-control study. Lancet 2001; 358: 1935–1940.
21. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57–70.
22. Guidez F, Zelent A. Role of nuclear receptor co-repressors in leukemogenesis. Curr Top Microbiol Immunol 2001; 254: 165–185.
23. Redner RL, Wang J, Liu J. Chromatin remodelling and leukemia: new therapeutic paradigms. Blood 1999; 94: 417–428.
24. Fenaux P, Chomienne C, Degos L. Treatment of acute promyelocytic leukaemia. Best Pract Res Clin Haematol 2001; 14: 153–174.
25. Druker BJ, Talpaz M, Resta DJ, Peng B, Buchdunger E, Ford JM, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med 2001; 344: 1031–1037.
26. Druker BJ, Sawyers CL, Kantarjian H, Resta DJ, Fernandes Reese S, Ford JM, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med 2001; 344: 1038–1042.
27. Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999; 286: 531–537.
28. Van Dongen JJM, Seriu T, Panzer-Grümayer ER, Biondi A, Pongers-Willemse MJ, Corral L, et al. Prognostic value of minimal residual disease in childhood acute lymphoblastic leukemia. Lancet 1998; 352: 1731–1738.