메뉴 건너뛰기




Volumn 22, Issue 5, 2005, Pages 369-376

KiSS1 suppresses metastasis in human ovarian cancer via inhibition of protein kinase C alpha

Author keywords

In vivo mouse model; KiSS1; Lysophosphatidic acid (LPA); Metastasis; Ovarian cancer; Protein kinase C (PKC)

Indexed keywords

AGAR; LYSOPHOSPHATIDIC ACID; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; SHORT HAIRPIN RNA; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN KISS1; UNCLASSIFIED DRUG;

EID: 27744480252     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-005-8186-4     Document Type: Article
Times cited : (115)

References (35)
  • 2
    • 0024436058 scopus 로고
    • Metastatic patterns in histologic variants of ovarian cancer. An autopsy study
    • PG Rose MS Piver Y Tsukada TS Lau 1989 Metastatic patterns in histologic variants of ovarian cancer. An autopsy study Cancer 64 1508 13
    • (1989) Cancer , vol.64 , pp. 1508-13
    • Rose, P.G.1    Piver, M.S.2    Tsukada, Y.3    Lau, T.S.4
  • 3
    • 0037264812 scopus 로고    scopus 로고
    • Metastasis suppressors alter the signal transduction of cancer cells
    • PS Steeg 2003 Metastasis suppressors alter the signal transduction of cancer cells Nat Rev Cancer 3 55 63
    • (2003) Nat Rev Cancer , vol.3 , pp. 55-63
    • Steeg, P.S.1
  • 4
    • 0038718523 scopus 로고    scopus 로고
    • A new member of the growing family of metastasis suppressors identified in prostate cancer
    • DR Welch KW Hunter 2003 A new member of the growing family of metastasis suppressors identified in prostate cancer J Natl Cancer Inst 95 839 41
    • (2003) J Natl Cancer Inst , vol.95 , pp. 839-41
    • Welch, D.R.1    Hunter, K.W.2
  • 5
    • 0030956852 scopus 로고    scopus 로고
    • Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1
    • JH Lee DR Welch 1997 Suppression of metastasis in human breast carcinoma MDA-MB-435 cells after transfection with the metastasis suppressor gene, KiSS-1 Cancer Res 57 2384 7
    • (1997) Cancer Res , vol.57 , pp. 2384-7
    • Lee, J.H.1    Welch, D.R.2
  • 6
    • 0029808561 scopus 로고    scopus 로고
    • KiSS-1, a novel human malignant melanoma metastasis-suppressor gene
    • JH Lee ME Miele D Hicks 1996 KiSS-1, a novel human malignant melanoma metastasis-suppressor gene J Natl Cancer Inst 88 1731 7
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1731-7
    • Lee, J.H.1    Miele, M.E.2    Hicks, D.3
  • 7
    • 0037217927 scopus 로고    scopus 로고
    • KISS1 metastasis suppression and emergent pathways
    • JF Harms DR Welch ME Miele 2003 KISS1 metastasis suppression and emergent pathways Clin Exp Metast 20 11 8
    • (2003) Clin Exp Metast , vol.20 , pp. 11-8
    • Harms, J.F.1    Welch, D.R.2    Miele, M.E.3
  • 8
    • 0035978639 scopus 로고    scopus 로고
    • Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor
    • T Ohtaki Y Shintani S Honda 2001 Metastasis suppressor gene KiSS-1 encodes peptide ligand of a G-protein-coupled receptor Nature 411 613 7
    • (2001) Nature , vol.411 , pp. 613-7
    • Ohtaki, T.1    Shintani, Y.2    Honda, S.3
  • 9
    • 0035860778 scopus 로고    scopus 로고
    • The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54
    • M Kotani M Detheux A Vandenbogaerde 2001 The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54 J Biol Chem 276 34631 6
    • (2001) J Biol Chem , vol.276 , pp. 34631-6
    • Kotani, M.1    Detheux, M.2    Vandenbogaerde, A.3
  • 10
    • 0035800824 scopus 로고    scopus 로고
    • AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1
    • AI Muir L Chamberlain NA Elshourbagy 2001 AXOR12, a novel human G protein-coupled receptor, activated by the peptide KiSS-1 J Biol Chem 276 28969 75
    • (2001) J Biol Chem , vol.276 , pp. 28969-75
    • Muir, A.I.1    Chamberlain, L.2    Elshourbagy, N.A.3
  • 11
    • 0036765743 scopus 로고    scopus 로고
    • Akt activation induced by lysophosphatidic acid and sphingosine-1- phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific
    • LM Baudhuin L Cristina J Lu Y Xu 2002 Akt activation induced by lysophosphatidic acid and sphingosine-1-phosphate requires both mitogen-activated protein kinase kinase and p38 mitogen-activated protein kinase and is cell-line specific Mol Pharmacol 62 660 71
    • (2002) Mol Pharmacol , vol.62 , pp. 660-71
    • Baudhuin, L.M.1    Cristina, L.2    Lu, J.3    Xu, Y.4
  • 12
    • 0042704741 scopus 로고    scopus 로고
    • A novel laminin-induced LPA autocrine loop in the migration of ovarian cancer cells
    • S Sengupta XJ Xiao Y Xu 2003 A novel laminin-induced LPA autocrine loop in the migration of ovarian cancer cells FASEB J 17 1570 2
    • (2003) FASEB J , vol.17 , pp. 1570-2
    • Sengupta, S.1    Xiao, X.J.2    Xu, Y.3
  • 13
    • 0024443170 scopus 로고
    • Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites
    • L Li JE Price D Fan 1989 Correlation of growth capacity of human tumor cells in hard agarose with their in vivo proliferative capacity at specific metastatic sites J Natl Cancer Inst 81 1406 12
    • (1989) J Natl Cancer Inst , vol.81 , pp. 1406-12
    • Li, L.1    Price, J.E.2    Fan, D.3
  • 14
    • 14044266895 scopus 로고    scopus 로고
    • Phorbol ester-induced apoptosis of C4-2 cells requires both a unique and a redundant protein kinase C signaling pathway
    • L Yin N Bennani-Baiti CT Powell 2005 Phorbol ester-induced apoptosis of C4-2 cells requires both a unique and a redundant protein kinase C signaling pathway J Biol Chem 280 5533 41
    • (2005) J Biol Chem , vol.280 , pp. 5533-41
    • Yin, L.1    Bennani-Baiti, N.2    Powell, C.T.3
  • 15
  • 16
    • 0036208331 scopus 로고    scopus 로고
    • Role of ether-linked lysophosphatidic acids in ovarian cancer cells
    • J Lu YJ Xiao LM Baudhuin G Hong Y Xu 2002 Role of ether-linked lysophosphatidic acids in ovarian cancer cells J Lipid Res 43 463 76
    • (2002) J Lipid Res , vol.43 , pp. 463-76
    • Lu, J.1    Xiao, Y.J.2    Baudhuin, L.M.3    Hong, G.4    Xu, Y.5
  • 17
    • 0037362947 scopus 로고    scopus 로고
    • Metastasis suppression: The evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site
    • EC Kauffman VL Robinson WM Stadler MH Sokoloff CW Rinker-Schaeffer 2003 Metastasis suppression: The evolving role of metastasis suppressor genes for regulating cancer cell growth at the secondary site J Urol 169 1122 33
    • (2003) J Urol , vol.169 , pp. 1122-33
    • Kauffman, E.C.1    Robinson, V.L.2    Stadler, W.M.3    Sokoloff, M.H.4    Rinker-Schaeffer, C.W.5
  • 18
    • 0037112512 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma
    • SD Yamada JA Hickson Y Hrobowski 2002 Mitogen-activated protein kinase kinase 4 (MKK4) acts as a metastasis suppressor gene in human ovarian carcinoma Cancer Res 62 6717 23
    • (2002) Cancer Res , vol.62 , pp. 6717-23
    • Yamada, S.D.1    Hickson, J.A.2    Hrobowski, Y.3
  • 19
    • 0037093198 scopus 로고    scopus 로고
    • Prolonged survival and decreased invasive activity attributable to dipeptidyl peptidase IV overexpression in ovarian carcinoma
    • H Kajiyama F Kikkawa T Suzuki K Shibata K Ino S Mizutani 2002 Prolonged survival and decreased invasive activity attributable to dipeptidyl peptidase IV overexpression in ovarian carcinoma Cancer Res 62 2753 7
    • (2002) Cancer Res , vol.62 , pp. 2753-7
    • Kajiyama, H.1    Kikkawa, F.2    Suzuki, T.3    Shibata, K.4    Ino, K.5    Mizutani, S.6
  • 20
    • 0033499057 scopus 로고    scopus 로고
    • Metastasis-suppressed C8161 melanoma cells arrest in lung but fail to proliferate
    • SF Goldberg JF Harms K Quon DR Welch 1999 Metastasis-suppressed C8161 melanoma cells arrest in lung but fail to proliferate Clin Exp Metast 17 601 7
    • (1999) Clin Exp Metast , vol.17 , pp. 601-7
    • Goldberg, S.F.1    Harms, J.F.2    Quon, K.3    Welch, D.R.4
  • 21
    • 0029867951 scopus 로고    scopus 로고
    • Metastasis suppressed, but tumorigenicity and local invasiveness unaffected, in the human melanoma cell line MelJuSo after introduction of human chromosomes 1 or 6
    • ME Miele G Robertson JH Lee 1996 Metastasis suppressed, but tumorigenicity and local invasiveness unaffected, in the human melanoma cell line MelJuSo after introduction of human chromosomes 1 or 6 Mol Carcinog 15 284 99
    • (1996) Mol Carcinog , vol.15 , pp. 284-99
    • Miele, M.E.1    Robertson, G.2    Lee, J.H.3
  • 22
    • 0034103092 scopus 로고    scopus 로고
    • A human melanoma metastasis-suppressor locus maps to 6q16.3-q23
    • ME Miele MD Jewett SF Goldberg 2000 A human melanoma metastasis- suppressor locus maps to 6q16.3-q23 Int J Cancer 86 524 8
    • (2000) Int J Cancer , vol.86 , pp. 524-8
    • Miele, M.E.1    Jewett, M.D.2    Goldberg, S.F.3
  • 23
    • 0028029129 scopus 로고
    • Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity
    • DR Welch P Chen ME Miele 1994 Microcell-mediated transfer of chromosome 6 into metastatic human C8161 melanoma cells suppresses metastasis but does not inhibit tumorigenicity Oncogene 9 255 62
    • (1994) Oncogene , vol.9 , pp. 255-62
    • Welch, D.R.1    Chen, P.2    Miele, M.E.3
  • 24
    • 18744372987 scopus 로고    scopus 로고
    • Transcriptional expression of genes involved in cell invasion and migration by normal and tumoral trophoblast cells
    • JL Janneau J Maldonado-Estrada G Tachdjian 2002 Transcriptional expression of genes involved in cell invasion and migration by normal and tumoral trophoblast cells J Clin Endocrinol Metab 87 5336 9
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5336-9
    • Janneau, J.L.1    Maldonado-Estrada, J.2    Tachdjian, G.3
  • 25
    • 2442608712 scopus 로고    scopus 로고
    • Expression of KiSS-1, a metastasis suppressor gene, in trophoblast giant cells of the rat placenta
    • Y Terao S Kumano Y Takatsu 2004 Expression of KiSS-1, a metastasis suppressor gene, in trophoblast giant cells of the rat placenta Biochim Biophys Acta 1678 102 10
    • (2004) Biochim Biophys Acta , vol.1678 , pp. 102-10
    • Terao, Y.1    Kumano, S.2    Takatsu, Y.3
  • 26
    • 0037323459 scopus 로고    scopus 로고
    • Dramatic elevation of plasma metastin concentrations in human pregnancy: Metastin as a novel placenta-derived hormone in humans
    • Y Horikoshi H Matsumoto Y Takatsu 2003 Dramatic elevation of plasma metastin concentrations in human pregnancy: Metastin as a novel placenta-derived hormone in humans J Clin Endocrinol Metab 88 914 9
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 914-9
    • Horikoshi, Y.1    Matsumoto, H.2    Takatsu, Y.3
  • 27
    • 0141814637 scopus 로고    scopus 로고
    • Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
    • N de Roux E Genin JC Carel 2003 Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54 Proc Natl Acad Sci USA 100 10972 6
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 10972-6
    • De Roux, N.1    Genin, E.2    Carel, J.C.3
  • 28
    • 0141639653 scopus 로고    scopus 로고
    • Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in hepatocellular carcinoma
    • M Ikeguchi Y Hirooka N Kaibara 2003 Quantitative reverse transcriptase polymerase chain reaction analysis for KiSS-1 and orphan G-protein-coupled receptor (hOT7T175) gene expression in hepatocellular carcinoma J Cancer Res Clin Oncol 129 531 5
    • (2003) J Cancer Res Clin Oncol , vol.129 , pp. 531-5
    • Ikeguchi, M.1    Hirooka, Y.2    Kaibara, N.3
  • 29
    • 10744221941 scopus 로고    scopus 로고
    • Metastin and its variant forms suppress migration of pancreatic cancer cells
    • T Masui R Doi T Mori 2004 Metastin and its variant forms suppress migration of pancreatic cancer cells Biochem Biophys Res Commun 315 85 92
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 85-92
    • Masui, T.1    Doi, R.2    Mori, T.3
  • 30
    • 1542619344 scopus 로고    scopus 로고
    • Protein kinase C isozymes as potential targets for anticancer therapy
    • H. Johann 2004 Protein kinase C isozymes as potential targets for anticancer therapy Curr Cancer Drug Targets 4 125 46
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 125-46
    • Johann, H.1
  • 31
    • 0033565261 scopus 로고    scopus 로고
    • PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic
    • T Ng D Shima A Squire 1999 PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic EMBO J 18 3909 23
    • (1999) EMBO J , vol.18 , pp. 3909-23
    • Ng, T.1    Shima, D.2    Squire, A.3
  • 32
    • 0033056944 scopus 로고    scopus 로고
    • Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells
    • SC Shih A Mullen K Abrams 1999 Role of protein kinase C isoforms in phorbol ester-induced vascular endothelial growth factor expression in human glioblastoma cells J Biol Chem 274 15407 14
    • (1999) J Biol Chem , vol.274 , pp. 15407-14
    • Shih, S.C.1    Mullen, A.2    Abrams, K.3
  • 33
    • 0033050632 scopus 로고    scopus 로고
    • Overexpression of protein kinase C alpha in MCF-10A human breast cells engenders dramatic alterations in morphology, proliferation, and motility
    • XG Sun SA Rotenberg 1999 Overexpression of protein kinase C alpha in MCF-10A human breast cells engenders dramatic alterations in morphology, proliferation, and motility Cell Growth Differ 10 343 52
    • (1999) Cell Growth Differ , vol.10 , pp. 343-52
    • Sun, X.G.1    Rotenberg, S.A.2
  • 34
    • 0034284266 scopus 로고    scopus 로고
    • Protein kinase C activation by phorbol ester increases in vitro invasion through regulation of matrix metalloproteinases/tissue inhibitors of metalloproteinases system in D54 human glioblastoma cells
    • MJ Park IC Park JH Hur 2000 Protein kinase C activation by phorbol ester increases in vitro invasion through regulation of matrix metalloproteinases/ tissue inhibitors of metalloproteinases system in D54 human glioblastoma cells Neurosci Lett 290 201 4
    • (2000) Neurosci Lett , vol.290 , pp. 201-4
    • Park, M.J.1    Park, I.C.2    Hur, J.H.3
  • 35
    • 0034818582 scopus 로고    scopus 로고
    • Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta
    • PK Gill A Gescher TW Gant 2001 Regulation of MDR1 promoter activity in human breast carcinoma cells by protein kinase C isozymes alpha and theta Eur J Biochem 268 4151 7
    • (2001) Eur J Biochem , vol.268 , pp. 4151-7
    • Gill, P.K.1    Gescher, A.2    Gant, T.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.