A new antihistamine levocetirizine inhibits eosinophil adhesion to vascular cell adhesion molecule-1 under flow conditions

Clinical and Experimental Allergy

Volumn 35, Issue 8, 2005, Pages 1073-1079

  Wu, P ^a   Mitchell, S ^b   Walsh, Garry M ^a,c  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b Dublin Molecular Medicine Centre   (Ireland)

^c UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Adhesion; Antihistamines; Eosinophils; Flow conditions; Levocetirizine; VCAM 1; VLA 4

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; LEVOCETIRIZINE; RECOMBINANT HUMAN VASCULAR CELL ADHESION MOLECULE 1; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; VERY LATE ACTIVATION ANTIGEN 4;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; DOSE RESPONSE; DRUG INHIBITION; DRUG MECHANISM; EOSINOPHIL; HUMAN; HUMAN CELL; IN VITRO STUDY; MICROSCOPY; NORMAL HUMAN; PRIORITY JOURNAL; SHEAR STRESS; VENULE;

ANTIBODIES, MONOCLONAL; CELL ADHESION; CETIRIZINE; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; EOSINOPHILS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HISTAMINE H1 ANTAGONISTS, NON-SEDATING; HUMANS; INTEGRIN ALPHA4BETA1; MICROSCOPY, CONFOCAL; MODELS, BIOLOGICAL; PIPERAZINES; RECOMBINANT PROTEINS; REGIONAL BLOOD FLOW; VASCULAR CELL ADHESION MOLECULE-1;

EID: 27744444340     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2005.02290.x     Document Type: Article

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