Blockade of 5-HT3 receptor with MDL7222 and Y25130 reduces hydrogen peroxide-induced neurotoxicity in cultured rat cortical cells

Life Sciences

Volumn 78, Issue 3, 2005, Pages 294-300

  Hyun, Joo Lee ^a   Ju, Yeon Ban ^a   Seong, Yeon Hee ^a  

^a Chungbuk National University   (South Korea)

Author keywords

5 HT3 receptor antagonists; Cortical neurons; H2O 2; MDL72222; Neuroprotection; Neurotoxicity; Y25130

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AZASETRON; BEMESETRON; CALCIUM ION; CASPASE 3; DIZOCILPINE; GLUTAMIC ACID; HOE 33342; HYDROGEN PEROXIDE; PHENYLBIGUANIDE; REACTIVE OXYGEN METABOLITE; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL CELL; ARTICLE; BRAIN CELL; CALCIUM TRANSPORT; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; NERVE CELL NECROSIS; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; RAT; RECEPTOR BLOCKING;

ANIMALS; APOPTOSIS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; GLUTAMIC ACID; HYDROGEN PEROXIDE; NEURONS; NEUROPROTECTIVE AGENTS; OXAZINES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTORS, SEROTONIN, 5-HT3; TROPANES;

ANIMALIA;

EID: 27644585777     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.04.043     Document Type: Article

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