Serotonin increases cytoplasmic Ca2+ concentration in PC12h cells: Effect of tachykinin peptides

Neuroscience Letters

Volumn 246, Issue 3, 1998, Pages 141-144

  Takenouchi, Takato ^a   Munekata, Eisuke ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

5 HT3 Receptor; 5 Hydroxytriptamine; Cytosolic calcium; Nicotinic acetylcholine receptor; Tachykinin peptides

Indexed keywords

NIFEDIPINE; SEROTONIN; SEROTONIN RECEPTOR; TACHYKININ RECEPTOR;

AMINO ACID ANALYSIS; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CYTOSOL; DRUG EFFECT; EXTRACELLULAR MATRIX; NEUROTRANSMITTER RELEASE; NONHUMAN; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALS; CALCIUM; CALCIUM CHANNELS; CALCIUM CHANNELS, L-TYPE; CALCIUM SIGNALING; CLONE CELLS; CYTOPLASM; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; FURA-2; METOCLOPRAMIDE; NIFEDIPINE; PC12 CELLS; PEPTIDES; RATS; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN; SODIUM; TACHYKININS;

EID: 0032502595     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00253-5     Document Type: Article

References (17)

1. 2+ uptake into cultured adrenal chromaffin cells. J. Neurochem. 45:1985;1895-1902.
2. Chan-Palay V., Jonsson G., Palay S.L. Serotonin and substance P coexist in neurons of the rat's central nervous system. Proc. Natl. Acad. Sci. USA. 75:1978;1582-1586.
3. Eiselé J.-L., Bertrand S., Galzi J.-L., Devillers-Thiéry A., Changeux J.-P., Bertrand D. Chimeric nicotinic-serotonergic receptor combines distinct ligand binding and channel specificities. Nature. 366:1993;479-483.
4. 3 receptors in PC12 cells treated with NGF and 8-Br-cAMP. J. Neurophysiol. 67:1992;812-819.
5. Geraghty D.P., Livett B.G., Rogerson F.M., Burcher E. A novel substance P binding site in bovine adrenal medulla. Neurosci. Lett. 112:1990;276-281.
6. 3 recognition sites in rat pheochromocytoma (PC12) cells. Life Sci. 46:1990;1435-1442.
7. 2+ indicators with greatly improved fluorescence properties. J. Biol. Chem. 260:1985;3440-3450.
8. Hatanaka H. Nerve growth factor-mediated stimulation of tyrosine hydroxylase activity in a clonal rat pheochromocytoma cell line. Brain Res. 222:1981;225-233.
9. Hökfelt T., Johansson O., Ljungdahl A., Lundberg J.M., Schultzberg M. Peptidergic neurones. Nature. 284:1980;515-521.
10. Humphrey P.P.A., Hartig P., Hoyer D. A proposed new nomenclature for 5HT receptors. Trends Pharmacol. Sci. 14:1993;233-236.
11. 3 receptor subunit. NeuroReport. 5:1993;121-124.
12. Khalil Z., Marley P.D., Livett B.G. Effect of substance P on nicotine-induced desensitization of cultured bovine adrenal chromaffin cells: possible receptor subtypes. Brain Res. 459:1988;282-288.
13. 3 recognition, a serotonin-gated ion channel. Science. 254:1991;432-437.
14. Munekata E., Kubo K., Tanaka H., Osakada F. Structure-activity studies of heptapeptide derivatives related to substance P, neurokinin A, B and other tachykinins on smooth muscles. Peptides. 8:1987;169-173.
15. Simasko S.M., Durkin J.A., Weiland G.A. Effects of substance P on nicotinic acetylcholine receptor function in PC12 cells. J. Neurochem. 49:1987;253-260.
16. 1) cell lines. J. Pharmacol. Exp. Ther. 235:1985;601-605.
17. 2+ influx in PC12h cells in culture. Neurosci. Lett. 173:1994;147-150.