Reversed DNA strand cleavage specificity in initiation of Cre-LoxP recombination induced by the His289Ala active-site substitution

Journal of Molecular Biology

Volumn 354, Issue 2, 2005, Pages 233-245

  Gelato, Kathy A ^a   Martin, Shelley S ^a   Baldwin, Enoch P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cre LoxP recombination; DNA cleavage specificity; Holliday junction resolution; Strand exchange order; Tyrosine site specific recombinase

Indexed keywords

ALANINE; CRE RECOMBINASE; DOUBLE STRANDED DNA; HISTIDINE; NUCLEOTIDE; PHOSPHATE; SPACER DNA;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ACID BASE BALANCE; AMINO ACID SUBSTITUTION; ARTICLE; CONFORMATION; DNA CLEAVAGE; DNA RECOMBINATION; DNA STRAND; HOLLIDAY JUNCTION; HYDROGEN BOND; ISOMERIZATION; LOXP SITE; PRIORITY JOURNAL; WILD TYPE;

EID: 27644584860     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.08.077     Document Type: Article

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