Control of IgE and selective TH1 and TH2 cytokines by PG102 isolated from Actinidia arguta

Journal of Allergy and Clinical Immunology

Volumn 116, Issue 5, 2005, Pages 1151-1157

  Park, Eun Jin ^a   Kim, Bongcheol ^b   Eo, Haekwan ^b   Park, Kyungcheol ^b   Kim, Yeonran ^b   Lee, Hwa Jun ^c   Son, Miwon ^d   Chang, Yoon Seok ^a   Cho, Sang Heon ^a   Kim, Sunyoung ^a   Jin, Mirim ^a,b  

^a Seoul National University   (South Korea)

^b PanGenomics Inc   (South Korea)

^c KyungHee Vincent Oriental Hospital   (South Korea)

^d R and D Center   (South Korea)

Author keywords

Actinidia arguta; GATA 3; IgE; NFATc2; PG102E; PG102T; T bet; TH1 TH2 cytokines

Indexed keywords

BINDING PROTEIN; CD19 ANTIGEN; CD4 ANTIGEN; CYTOKINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN E; IMMUNOMODULATING AGENT; INTERLEUKIN 4; PG 102; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

ALLERGIC DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG ISOLATION; EXPERIMENTATION; FEMALE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; KIWIFRUIT; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION; SPLEEN; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

ACTINIDIA; ADMINISTRATION, ORAL; ANIMALS; B-LYMPHOCYTES; CELL LINE, TUMOR; CYTOKINES; FEMALE; IMMUNIZATION; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ISOTYPES; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED BALB C; OVALBUMIN; PLANT EXTRACTS; SPLEEN; T-LYMPHOCYTES; TH1 CELLS; TH2 CELLS; TRANSCRIPTION FACTORS;

EID: 27644582729     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2005.07.024     Document Type: Article

References (20)

1. A.K. Abbas, K.M. Murphy, and A. Sher Functional diversity of helper T lymphocytes Nature 383 1991 787 793
2. D. Vercelli Immunoglobulin E and its regulators Curr Opin Allergy Clin Immunol 1 2001 61 65
3. D.T. Umetsu, and R.H. DeKruyff TH1 and TH2 CD4+ cells in human allergic diseases J Allergy Clin Immunol 100 1997 1 6
4. R.L. Coffman, and J. Carty A T cell activity that enhances polyclonal IgE production and its inhibition by interferon-gamma J Immunol 136 1986 949 954
5. S.H. Gavett, D.J. O'Hearn, X. Li, S.K. Huang, F.D. Finkelman, and M. Wills-Karp Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice J Exp Med 182 1995 1527 1536
6. H.J. Lee, N. Takemoto, H. Kurata, Y. Kamogawa, S. Miyatake, and A. O'Garra GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells J Exp Med 192 2000 105 115
7. C.N. Ting, M.C. Olson, K.P. Barton, and J.M. Leiden Transcription factor GATA-3 is required for development of the T-cell lineage Nature 384 1996 474 478
8. A.A. Lighvani, D.M. Frucht, D. Jankovic, H. Yamane, J. Aliberti, and B.D. Hissong T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells Proc Natl Acad Sci U S A 98 2001 15137 15142
9. S.J. Szabo, S.T. Kim, G.L. Costa, X. Zhang, C.G. Fathman, and L.H. Glimcher A novel transcription factor, T-bet, directs Th1 lineage commitment Cell 100 2000 655 669
10. Y. Kato, T. Manabe, Y. Tanaka, and H. Mochizuki Effect of an orally active Th1/Th2 balance modulator, M50367, on IgE production, eosinophilia, and airway hyperresponsiveness in mice J Immunol 162 1999 7470 7479
11. C.L. Hofstra, I. Van Ark, G. Hofman, M. Kool, F.P. Nijkamp, and A.J. Van Oosterhout Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels J Immunol 161 1998 5054 5060
12. A. Tomkinson, C. Duez, G. Cieslewicz, J.C. Pratt, A. Joetham, and M.C. Shanafelt A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness J Immunol 166 2001 5792 5800
13. H.W. Kang, K.W. Yu, W.J. Jun, I.S. Chang, S.B. Han, and H.Y. Kim Isolation and characterization of alkyl peroxy radical scavenging compound from leaves of Laurus nobilis Biol Pharm Bull 25 1 2002 102 108
14. H.M. Kim, J.H. Lee, J.H. Won, E.J. Park, H.J. Chae, and H.R. Kim Inhibitory effect on immunoglobulin E production in vivo and in vitro by Siegesbeckia glabrescens Phytother Res 15 2001 572 576
15. T. Hirano, N. Yamakawa, H. Miyajima, K. Maeda, S. Takai, and A. Ueda An improved method for the detection of IgE antibody of defined specificity by ELISA using rat monoclonal anti-IgE antibody J Immunol Methods 119 1989 145 150
16. K. Kyoko, S. Yoshinao, K. Yoko, and M. Masako Flow cytometric analysis of IL-4, IL-13 and IFN-γ expression in peripheral blood mononuclear cells and detection of circulating IL-13 in patients with atopic dermatitis provide evidence for the involvement of type 2 cytokines in the disease J Dermatol Sci 29 2002 19 25
17. A.E. Semper, K. Heron, A.C.S. Woollard, J.P. Kochan, P.S. Friedmann, and M.K. Church Surface expression of FcεRI on Langerhans' cells of clinically uninvolved skin is associated with disease activity in atopic dermatitis, allergic asthma, and rhinitis J Allergy Clin Immunol 112 2003 141 149
18. A. Kiani, F.J. Garcia-Cozar, I. Habermann, S. Laforsch, T. Aebischer, and G. Ehninger Regulation of interferon-gamma gene expression by nuclear factor of activated T cells Blood 98 2001 1480 1488
19. I.M. Adcock Glucocorticoid-regulated transcription factors Pulm Pharmacol Ther 14 2001 211 219
20. A.J. Gerth, L. Lin, and S.L. Peng T-bet regulates T-independent IgG2a class switching Int Immunol 15 2003 937 944