Listeriolysin O, a cytolysin derived from Listeria monocytogenes, inhibits generation of ovalbumin-specific Th2 immune response by skewing maturation of antigen-specific T cells into Th1 cells

Clinical and Experimental Immunology

Volumn 142, Issue 2, 2005, Pages 268-274

  Yamamoto, K ^a   Kawamura, Ikuo ^a   Tominaga, T ^a   Nomura, T ^a   Kohda, C ^b   Ito, J ^a   Mitsuyama, M ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SHOWA UNIVERSITY   (Japan)

Author keywords

Allergic rhinitis; GATA 3; Listeriolysin O; SOCS 3; T bet

Indexed keywords

ALUMINUM POTASSIUM SULFATE; BACTERIAL PROTEIN; CD4 ANTIGEN; CYTOLYSIN; GAMMA INTERFERON; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; INTERLEUKIN 12; INTERLEUKIN 18; INTERLEUKIN 4; INTERLEUKIN 5; LISTERIOLYSIN; LISTERIOLYSIN O; OVALBUMIN; RECOMBINANT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRANSCRIPTION FACTOR GATA 3; UNCLASSIFIED DRUG;

ALLERGIC RHINITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY PRODUCTION; ANTIBODY TITER; ANTIGEN SPECIFICITY; ARTICLE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; EOSINOPHIL; FEMALE; IMMUNE RESPONSE; IMMUNITY; LISTERIA MONOCYTOGENES; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSITIZATION; T LYMPHOCYTE; TH1 CELL; TH2 CELL;

ANIMALS; BACTERIAL TOXINS; CELL DIFFERENTIATION; EPITOPES, T-LYMPHOCYTE; FEMALE; GATA3 TRANSCRIPTION FACTOR; GENE EXPRESSION; HEAT-SHOCK PROTEINS; HEMOLYSIN PROTEINS; INTERFERON TYPE II; MICE; MICE, INBRED BALB C; OVALBUMIN; RECOMBINANT PROTEINS; RHINITIS; RNA, MESSENGER; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; T-BOX DOMAIN PROTEINS; TH1 CELLS; TH2 CELLS; TRANSCRIPTION FACTORS;

EID: 27644581148     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2005.02922.x     Document Type: Article

References (32)

1. Low JC, Donachie W. A review of Listeria monocytogenes and listeriosis. Vet J 1997; 153:9-29.
2. Portnoy DA, Chakraborty T, Goebel W, Cossart P. Molecular determinants of Listeria monocytogenes pathogenesis. Infect Immun 1992; 60:1263-7.
3. Vazquez-Boland JA, Dominguez-Bernal G, Gonzalez-Zorn B, Kreft J, Goebel W. Pathogenicity islands and virulence evolution in Listeria. Microb Infect 2001; 3:571-84.
4. Alouf JE. Introduction of the family of the structurally-related cholesterol-binding cytolysins (sulphydryl-activated toxins). In: Alouf JE, Freer JH, eds. The comprehensive sourcebook of bacterial toxins, 2nd edn. London: Academic Press, 1999:443-56.
5. Lety M-A, Frehel C, Dubail I, Beretti J-L, Kayal S, Berche P, Charbit A. Identification of a PEST-like motif in listeriolysin O required for phagosomal escape and for virulence in Listeria monocytogenes. Mol Microbiol 2001; 39:1124-39.
6. Yoshikawa H, Kawamura I, Fujita M, Tsukada H, Arakawa M, Mitsuyama M. Membrane damage and interleukin-1 production in murine macrophages exposed to listeriolysin O. Infect Immun 1993; 61:1334-9.
7. Nishibori T, Xiong H, Kawamura I, Arakawa M, Mitsuyama M. Induction of cytokine gene expression by listeriolysin O and roles of macrophages and NK cells. Infect Immun 1996; 64:3188-95.
8. Nomura T, Kawamura I, Tsuchiya K et al. Essential role of interleukin-12 (IL-12) and IL-18 for gamma interferon production induced by listeriolysin O in mouse spleen cells. Infect Immun 2002; 70:1049-55.
9. Tanabe Y, Xiong H, Nomura T, Arakawa M, Mitsuyama M. Induction of protective T cells against Listeria monocytogenes in mice by immunization with a listeriolysin O-negative avirulent strain of bacteria and liposome-encapsulated listeriolysin O. Infect Immun 1999; 67:568-75.
10. Xiong H, Kawamura I, Nishibori T, Mitsuyama M. Cytokine gene expression in mice at an early stage of infection with various strains of Listeria spp. differing in virulence. Infect Immun 1994; 62:3649-54.
11. Okano M, Nishizaki K, Nakada M et al. Prevalence and prediction of allergic rhinitis using questionnaire and nasal smear examination in schoolchildren. Acta Otolaryngol (Suppl) 1999; 540:58-63.
12. Kohda C, Kawamura I, Baba H et al. Dissociated linkage of cytokine-inducing activity and cytotoxicity to different domains of listeriolysin O from Listeria monocytogenes. Infect Immun 2002; 70:1334-41.
13. Beauregard KE, Lee K-D, Collier RJ, Swanson JA. pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes. J Exp Med 1997; 186:1159-63.
14. Saito H, Howie K, Wattie J, Denburg A, Ellis R. Allergen-induced murine upper airway inflammation: local and systemic changes in murine experimental allergic rhinitis. Immunology 2001; 104:226-34.
15. Kline JN, Kitagaki K, Businga TR, Jain VV. Treatment of established asthma in a murine model using CpG oligodeoxynucleotides. Am J Physiol Lung Cell Mol Physiol 2002; 283:L170-9.
16. Okano M, Nishizaki K, Abe M et al. Strain-dependent induction of allergic rhinitis without adjuvant in mice. Allergy 1999; 54:593-601.
17. Usui T, Nishikomori R, Kitani A, Strober W. GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rβ2 chain or T-bet. Immunity 2003; 18:415-28.
18. Fox SW, Haque SJ, Lovibond AC, Chambers TJ. The possible role of TGF-β-induced suppressors of cytokine signaling expression in osteoclast/macrophage lineage commitment in vitro. J Immunol 2003; 170:3679-87.
19. Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell 2000; 100:655-69.
20. Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997; 89:587-96.
21. H2-mediated allergic responses. Nat Med 2003; 9:1047-54.
22. Lighvani AA, Frucht DM, Jankovic D et al. T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells. PNAS 2001; 98:15137-42.
23. Yates A, Callard R, Stark J. Combining cytokine signalling with T-bet and GATA-3 regulation in Th1 and Th2 differentiation: a model for cellular decision-making. J Theor Biol 2004; 231:181-96.
24. Liu N, Ohnishi N, Ni L, Akira S, Bacon KB. CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells. Nat Immunol 2003; 4:687-93.
25. Ito Y, Kawamura I, Kohda C et al. Seeligeriolysin O, a cholesterol-dependent cytolysin of Listeria seeligeri, induces gamma interferon from spleen cells of mice. Infect Immun 2003; 71:234-41.
26. Seki N, Miyazaki M, Suzuki W et al. IL-4-induced GATA-3 expression is a time-restricted instruction switch for Th2 cell differentiation. J Immunol 2004; 172:6158-66.
27. Major T, Wohlleben G, Reibetanz B, Erb KJ. Application of heat killed Mycobacterium bovis-BCG into the lung inhibits the development of allergen-induced Th2 responses. Vaccine 2002; 20:1532-10.
28. Zuany-Amorim C, Sawicka E, Manlius C et al. Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells. Nat Med 2002; 8:625-9.
29. + T cells and IL-18. J Immunol 2000; 164:223-30.
30. Redecke V, Hacker H, Datta SK et al. Cutting edge, activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J Immunol 2004; 172:2739-43.
31. Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, Bottomly K. Lipopolysaccharide-enhanced, Toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 2002; 196:1645-51.
32. Park JM, Ng VH, Maeda S, Rest RF, Karin M. Anthrolysin O and other Gram-positive cytolysins are Toll-like receptor 4 agonists. J Exp Med 2004; 200:1647-55.