Amino acid mutations essential to production of an altered PBP 2X: Conferring high-level β-lactam resistance in a clinical isolate of Streptococcus pneumoniae

Antimicrobial Agents and Chemotherapy

Volumn 49, Issue 11, 2005, Pages 4622-4627

  Smith, Anthony M ^a,c   Klugman, Keith P ^a,b  

^a UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^b EMORY UNIVERSITY   (United States)

^c NATIONAL INSTITUTE FOR COMMUNICABLE DISEASES   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; AMINO ACID; ARGININE; BETA LACTAM ANTIBIOTIC; CEFOTAXIME; CEPHALOSPORIN; GLYCINE; ISOLEUCINE; LEUCINE; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 2X; PENICILLIN G; PHENYLALANINE; PROLINE; THREONINE; TYROSINE; UNCLASSIFIED DRUG; VALINE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PENICILLIN RESISTANCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SITE DIRECTED MUTAGENESIS; STREPTOCOCCUS PNEUMONIAE;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BETA-LACTAM RESISTANCE; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; PENICILLIN-BINDING PROTEINS; STREPTOCOCCUS PNEUMONIAE;

EID: 27644451319     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.49.11.4622-4627.2005     Document Type: Article

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