Oral administration of geranylgeranylacetone improves survival rate in a rat endotoxin shock model: Administration timing and heat shock protein 70 induction

Shock

Volumn 24, Issue 5, 2005, Pages 482-487

  Nakada, Junya ^a   Matsura, Tatsuya ^a   Okazaki, Naoto ^a   Nishida, Tadashi ^a   Togawa, Aki ^a   Minami, Yukari ^a   Inagaki, Yoshimi ^a   Ito, Hisao ^a   Yamada, Kazuo ^a   Ishibe, Yuichi ^a  

^a TOTTORI UNIVERSITY   (Japan)

Author keywords

Cytokine; Endotoxin shock; Geranylgeranylacetone; Heat shock protein 70; Lipopolysaccharide; Nitric oxide; Rat

Indexed keywords

CYTOKINE; ENDOTOXIN; HEAT SHOCK PROTEIN 70; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; NITRIC OXIDE; QUERCETIN; TEPRENONE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; KIDNEY INJURY; LIVER INJURY; MALE; MORTALITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; SEPTIC SHOCK; SURVIVAL; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ADMINISTRATION, ORAL; ANIMALS; ANTI-ULCER AGENTS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTOXINS; HSP70 HEAT-SHOCK PROTEINS; INFLAMMATION; INTERLEUKIN-6; KIDNEY; LIPOPOLYSACCHARIDES; MALE; NITRIC OXIDE; RATS; RATS, SPRAGUE-DAWLEY; SHOCK; TIME FACTORS; TREATMENT OUTCOME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 27644440326     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.shk.0000180980.63247.a9     Document Type: Article

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