메뉴 건너뛰기




Volumn 116, Issue 3, 2005, Pages 337-346

HLA Class II molecules on haplotypes associated with type 1 diabetes exhibit similar patterns of binding affinities for coxsackievirus P2C peptides

Author keywords

Antigen presentation; Autoimmunity; Diabetes; Major histocompatibility complex; Viruses

Indexed keywords

GLUTAMATE DECARBOXYLASE; HLA ANTIGEN CLASS 2; HLA DQ2 ANTIGEN; HLA DQ8 ANTIGEN; HLA DR3 ANTIGEN; HLA DR4 ANTIGEN; PROTEIN P2C; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 27544465437     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2005.02233.x     Document Type: Article
Times cited : (17)

References (41)
  • 1
    • 0031849829 scopus 로고    scopus 로고
    • Dissecting the genetics of type 1 diabetes: Relevance for familial clustering and differences in incidence
    • Buzzetti R, Quattrocchi CC, Nistico L. Dissecting the genetics of type 1 diabetes: relevance for familial clustering and differences in incidence. Diabetes Metab Rev 1998; 14:111-28.
    • (1998) Diabetes Metab Rev , vol.14 , pp. 111-128
    • Buzzetti, R.1    Quattrocchi, C.C.2    Nistico, L.3
  • 2
  • 4
    • 0018799757 scopus 로고
    • Isolation of a virus from the pancreas of a child with diabetic ketoacidosis
    • Yoon JW, Austin M, Onodera T, Notkins AL. Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N Engl J Med 1979; 300:1173-9.
    • (1979) N Engl J Med , vol.300 , pp. 1173-1179
    • Yoon, J.W.1    Austin, M.2    Onodera, T.3    Notkins, A.L.4
  • 5
    • 0029034877 scopus 로고
    • Coxsackie B virus infection and onset of childhood diabetes
    • Clements GB, Galbraith DN, Taylor KW. Coxsackie B virus infection and onset of childhood diabetes. Lancet 1995; 346 (8969):221-3.
    • (1995) Lancet , vol.346 , Issue.8969 , pp. 221-223
    • Clements, G.B.1    Galbraith, D.N.2    Taylor, K.W.3
  • 6
    • 16944362663 scopus 로고    scopus 로고
    • Islet cell antibody seroconversion in children is temporally associated with enterovirus infections
    • Childhood Diabetes in Finland (DiMe) Study Group
    • Hiltunen M, Hyoty H, Knip M et al. Islet cell antibody seroconversion in children is temporally associated with enterovirus infections. Childhood Diabetes in Finland (DiMe) Study Group. J Infect Dis 1997; 175:554-60.
    • (1997) J Infect Dis , vol.175 , pp. 554-560
    • Hiltunen, M.1    Hyoty, H.2    Knip, M.3
  • 7
    • 20244384697 scopus 로고
    • A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM
    • Childhood Diabetes Finland (Dime) Study Group
    • Hyoty H, Hiltunen M, Knip M et al. A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM. Childhood Diabetes Finland (Dime) Study Group. Diabetes 1995; 44:652-7.
    • (1995) Diabetes , vol.44 , pp. 652-657
    • Hyoty, H.1    Hiltunen, M.2    Knip, M.3
  • 8
    • 0343618660 scopus 로고    scopus 로고
    • Enterovirus RNA in serum is a risk factor for beta-cell autoimmunity and clinical type 1 diabetes: A prospective study
    • Childhood Diabetes in Finland (DiMe) Study Group
    • Lonnrot M, Salminen K, Knip M et al. Enterovirus RNA in serum is a risk factor for beta-cell autoimmunity and clinical type 1 diabetes: a prospective study. Childhood Diabetes in Finland (DiMe) Study Group. J Med Virol 2000; 61:214-20.
    • (2000) J Med Virol , vol.61 , pp. 214-220
    • Lonnrot, M.1    Salminen, K.2    Knip, M.3
  • 9
    • 0037211477 scopus 로고    scopus 로고
    • Enterovirus infections are associated with the induction of beta-cell autoimmunity in a prospective birth cohort study
    • Salminen K, Sadeharju K, Lonnrot M et al. Enterovirus infections are associated with the induction of beta-cell autoimmunity in a prospective birth cohort study. J Med Virol 2003; 69:91-8.
    • (2003) J Med Virol , vol.69 , pp. 91-98
    • Salminen, K.1    Sadeharju, K.2    Lonnrot, M.3
  • 10
    • 0032751826 scopus 로고    scopus 로고
    • Enterovirus variants in the serum of children at the onset of Type 1 diabetes mellitus
    • Nairn C, Galbraith DN, Taylor KW, Clements GB. Enterovirus variants in the serum of children at the onset of Type 1 diabetes mellitus. Diabet Med 1999; 16:509-13.
    • (1999) Diabet Med , vol.16 , pp. 509-513
    • Nairn, C.1    Galbraith, D.N.2    Taylor, K.W.3    Clements, G.B.4
  • 12
    • 0036263328 scopus 로고    scopus 로고
    • Characterization of the T-cell response to coxsackievirus B4: Evidence that effector memory cells predominate in patients with type 1 diabetes
    • Varela-Calvino R, Ellis R, Sgarbi G, Dayan CM, Peakman M. Characterization of the T-cell response to coxsackievirus B4: evidence that effector memory cells predominate in patients with type 1 diabetes. Diabetes 2002; 51:1745-53.
    • (2002) Diabetes , vol.51 , pp. 1745-1753
    • Varela-Calvino, R.1    Ellis, R.2    Sgarbi, G.3    Dayan, C.M.4    Peakman, M.5
  • 13
    • 10044238928 scopus 로고    scopus 로고
    • Identification of a naturally processed cytotoxic CD8 T-cell epitope of coxsackievirus B4, presented by HLA-A2.1 and located in the PEVKEK region of the P2C nonstructural protein
    • Varela-Calvino R, Skowera A, Arif S, Peakman M. Identification of a naturally processed cytotoxic CD8 T-cell epitope of coxsackievirus B4, presented by HLA-A2.1 and located in the PEVKEK region of the P2C nonstructural protein. J Virol 2004; 78:13399-408.
    • (2004) J Virol , vol.78 , pp. 13399-13408
    • Varela-Calvino, R.1    Skowera, A.2    Arif, S.3    Peakman, M.4
  • 14
    • 0034777837 scopus 로고    scopus 로고
    • A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins
    • Cucca F, Lampis R, Congia M, Angius E, Nutland S, Bain SC, Barnett AH, Todd JA. A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins. Hum Mol Genet 2001; 10:2025-37.
    • (2001) Hum Mol Genet , vol.10 , pp. 2025-2037
    • Cucca, F.1    Lampis, R.2    Congia, M.3    Angius, E.4    Nutland, S.5    Bain, S.C.6    Barnett, A.H.7    Todd, J.A.8
  • 15
    • 0028593495 scopus 로고
    • Complete nucleotide sequence of a strain of coxsackie B4 virus of human origin that induces diabetes in mice and its comparison with nondiabetogenic coxsackie B4 JBV strain
    • Kang Y, Chatterjee NK, Nodwell MJ, Yoon JW. Complete nucleotide sequence of a strain of coxsackie B4 virus of human origin that induces diabetes in mice and its comparison with nondiabetogenic coxsackie B4 JBV strain. J Med Virol 1994; 44:353-61.
    • (1994) J Med Virol , vol.44 , pp. 353-361
    • Kang, Y.1    Chatterjee, N.K.2    Nodwell, M.J.3    Yoon, J.W.4
  • 16
    • 0023639662 scopus 로고
    • Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line
    • Gorga JC, Horejsi V, Johnson DR, Raghupathy R, Strominger JL. Purification and characterization of class II histocompatibility antigens from a homozygous human B cell line. J Biol Chem 1987; 262:16087-94.
    • (1987) J Biol Chem , vol.262 , pp. 16087-16094
    • Gorga, J.C.1    Horejsi, V.2    Johnson, D.R.3    Raghupathy, R.4    Strominger, J.L.5
  • 17
    • 0032701129 scopus 로고    scopus 로고
    • Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4
    • Peakman M, Stevens EJ, Lohmann T et al. Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4. J Clin Invest 1999; 104:1449-57.
    • (1999) J Clin Invest , vol.104 , pp. 1449-1457
    • Peakman, M.1    Stevens, E.J.2    Lohmann, T.3
  • 18
    • 0023746461 scopus 로고
    • Purification and characterization of a strain of coxsackievirus B4 of human origin that induces diabetes in mice
    • Chatterjee NK, Nejman C, Gerling I. Purification and characterization of a strain of coxsackievirus B4 of human origin that induces diabetes in mice. J Med Virol 1988; 26:57-69.
    • (1988) J Med Virol , vol.26 , pp. 57-69
    • Chatterjee, N.K.1    Nejman, C.2    Gerling, I.3
  • 19
    • 0038632181 scopus 로고    scopus 로고
    • Promiscuous binding of proinsulin peptides to Type 1 diabetes-permissive and -protective HLA class II molecules
    • Astill TP, Ellis RJ, Arif S, Tree TI, Peakman M. Promiscuous binding of proinsulin peptides to Type 1 diabetes-permissive and -protective HLA class II molecules. Diabetologia 2003; 46:496-503.
    • (2003) Diabetologia , vol.46 , pp. 496-503
    • Astill, T.P.1    Ellis, R.J.2    Arif, S.3    Tree, T.I.4    Peakman, M.5
  • 20
    • 0026733449 scopus 로고
    • Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size
    • Chicz RM, Urban RG, Lane WS, Gorga JC, Stern LJ, Vignali DA, Strominger JL. Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size. Nature 1992; 358 (6389):764-8.
    • (1992) Nature , vol.358 , Issue.6389 , pp. 764-768
    • Chicz, R.M.1    Urban, R.G.2    Lane, W.S.3    Gorga, J.C.4    Stern, L.J.5    Vignali, D.A.6    Strominger, J.L.7
  • 21
    • 0033829857 scopus 로고    scopus 로고
    • Binding of conserved islet peptides by human and murine MHC class II molecules associated with susceptibility to type I diabetes
    • Yu B, Gauthier L, Hausmann DH, Wucherpfennig KW. Binding of conserved islet peptides by human and murine MHC class II molecules associated with susceptibility to type I diabetes. Eur J Immunol 2000; 30:2497-506.
    • (2000) Eur J Immunol , vol.30 , pp. 2497-2506
    • Yu, B.1    Gauthier, L.2    Hausmann, D.H.3    Wucherpfennig, K.W.4
  • 23
    • 0036727207 scopus 로고    scopus 로고
    • Prediction of MHC class I binding peptides using profile motifs
    • Reche PA, Glutting JP, Reinherz EL. Prediction of MHC class I binding peptides using profile motifs. Hum Immunol 2002; 63:701-9.
    • (2002) Hum Immunol , vol.63 , pp. 701-709
    • Reche, P.A.1    Glutting, J.P.2    Reinherz, E.L.3
  • 24
    • 0036137241 scopus 로고    scopus 로고
    • ProPred: Prediction of HLA-DR binding sites
    • Singh H, Raghava GP. ProPred: prediction of HLA-DR binding sites. Bioinformatics 2001; 17:1236-7.
    • (2001) Bioinformatics , vol.17 , pp. 1236-1237
    • Singh, H.1    Raghava, G.P.2
  • 25
    • 0016749424 scopus 로고
    • Primer on certain elements of medical decision making
    • McNeil BJ, Keller E, Adelstein SJ. Primer on certain elements of medical decision making. N Engl J Med 1975; 29:211-15.
    • (1975) N Engl J Med , vol.29 , pp. 211-215
    • McNeil, B.J.1    Keller, E.2    Adelstein, S.J.3
  • 26
    • 0022500965 scopus 로고
    • The use of relative operating characteristic (ROC) curves in test performance evaluation
    • Beck JR, Shultz EK. The use of relative operating characteristic (ROC) curves in test performance evaluation. Arch Pathol Lab Med 1986; 110:13-20.
    • (1986) Arch Pathol Lab Med , vol.110 , pp. 13-20
    • Beck, J.R.1    Shultz, E.K.2
  • 28
    • 0031883094 scopus 로고    scopus 로고
    • Molecular mimicry in diabetes mellitus. The homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule
    • Vreugdenhil GR, Geluk A, Ottenhoff TH, Melchers WJ, Roep BO, Galama JM. Molecular mimicry in diabetes mellitus. the homologous domain in coxsackie B virus protein 2C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule. Diabetologia 1998; 41:40-6.
    • (1998) Diabetologia , vol.41 , pp. 40-46
    • Vreugdenhil, G.R.1    Geluk, A.2    Ottenhoff, T.H.3    Melchers, W.J.4    Roep, B.O.5    Galama, J.M.6
  • 29
    • 4344648997 scopus 로고    scopus 로고
    • Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease
    • Koeleman BP, Lie BA, Undlien DE et al. Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease. Genes Immun 2004; 5:381-8.
    • (2004) Genes Immun , vol.5 , pp. 381-388
    • Koeleman, B.P.1    Lie, B.A.2    Undlien, D.E.3
  • 30
    • 0023912807 scopus 로고
    • A molecular basis for MHC class II-associated autoimmunity
    • Todd JA, Acha-Orbea H, Bell JI et al. A molecular basis for MHC class II-associated autoimmunity. Science 1988; 240 (4855):1003-9.
    • (1988) Science , vol.240 , Issue.4855 , pp. 1003-1009
    • Todd, J.A.1    Acha-Orbea, H.2    Bell, J.I.3
  • 31
    • 0035947123 scopus 로고    scopus 로고
    • Responses of coxsackievirus B4-specific T-cell lines to 2C protein-characterization of epitopes with special reference to the GAD65 homology region
    • Marttila J, Juhela S, Vaarala O et al. Responses of coxsackievirus B4-specific T-cell lines to 2C protein-characterization of epitopes with special reference to the GAD65 homology region. Virology 2001; 284:131-41.
    • (2001) Virology , vol.284 , pp. 131-141
    • Marttila, J.1    Juhela, S.2    Vaarala, O.3
  • 32
    • 0033021020 scopus 로고    scopus 로고
    • Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices
    • Sturniolo T, Bono E, Ding J et al. Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices. Nat Biotechnol 1999; 17:555-61.
    • (1999) Nat Biotechnol , vol.17 , pp. 555-561
    • Sturniolo, T.1    Bono, E.2    Ding, J.3
  • 33
    • 0028842070 scopus 로고
    • Several HLA alleles share overlapping peptide specificities
    • Sidney J, del Guercio MF, Southwood S et al. Several HLA alleles share overlapping peptide specificities. J Immunol 1995; 154:247-59.
    • (1995) J Immunol , vol.154 , pp. 247-259
    • Sidney, J.1    Del Guercio, M.F.2    Southwood, S.3
  • 34
    • 0032055915 scopus 로고    scopus 로고
    • Several common HLA-DR types share largely overlapping peptide binding repertoires
    • Southwood S, Sidney J, Kondo A et al. Several common HLA-DR types share largely overlapping peptide binding repertoires. J Immunol 1998; 160:3363-73.
    • (1998) J Immunol , vol.160 , pp. 3363-3373
    • Southwood, S.1    Sidney, J.2    Kondo, A.3
  • 35
    • 0036838698 scopus 로고    scopus 로고
    • The HLA molecules DQA1*0501/B1*0201 and DQA1*0301/B1 *0302 share an extensive overlap in peptide binding specificity
    • Sidney J, del Guercio MF, Southwood S, Sette A. The HLA molecules DQA1*0501/B1*0201 and DQA1*0301/B1*0302 share an extensive overlap in peptide binding specificity. J Immunol 2002; 169:5098-108.
    • (2002) J Immunol , vol.169 , pp. 5098-5108
    • Sidney, J.1    Del Guercio, M.F.2    Southwood, S.3    Sette, A.4
  • 36
    • 0033619915 scopus 로고    scopus 로고
    • Molecular mimicry and autoimmunity
    • Albert LJ, Inman RD. Molecular mimicry and autoimmunity. N Engl J Med 1999; 341:2068-74.
    • (1999) N Engl J Med , vol.341 , pp. 2068-2074
    • Albert, L.J.1    Inman, R.D.2
  • 37
    • 0028007192 scopus 로고
    • Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes
    • Atkinson MA, Bowman MA, Campbell L, Darrow BL, Kaufman DL, Maclaren NK. Cellular immunity to a determinant common to glutamate decarboxylase and coxsackie virus in insulin-dependent diabetes. J Clin Invest 1994; 94:2125-9.
    • (1994) J Clin Invest , vol.94 , pp. 2125-2129
    • Atkinson, M.A.1    Bowman, M.A.2    Campbell, L.3    Darrow, B.L.4    Kaufman, D.L.5    Maclaren, N.K.6
  • 38
    • 0035044922 scopus 로고    scopus 로고
    • Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart
    • Schloot NC, Willemen SJ, Duinkerken G, Drijfhout JW, de Vries RR, Roep BO. Molecular mimicry in type 1 diabetes mellitus revisited: T-cell clones to GAD65 peptides with sequence homology to Coxsackie or proinsulin peptides do not crossreact with homologous counterpart. Hum Immunol 2001; 62:299-309.
    • (2001) Hum Immunol , vol.62 , pp. 299-309
    • Schloot, N.C.1    Willemen, S.J.2    Duinkerken, G.3    Drijfhout, J.W.4    De Vries, R.R.5    Roep, B.O.6
  • 39
    • 2442705373 scopus 로고    scopus 로고
    • Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201
    • Pelte C, Cherepnev G, Wang Y, Schoenemann C, Volk HD, Kern F. Random screening of proteins for HLA-A*0201-binding nine-amino acid peptides is not sufficient for identifying CD8 T cell epitopes recognized in the context of HLA-A*0201. J Immunol 2004; 172:6783-9.
    • (2004) J Immunol , vol.172 , pp. 6783-6789
    • Pelte, C.1    Cherepnev, G.2    Wang, Y.3    Schoenemann, C.4    Volk, H.D.5    Kern, F.6
  • 40
    • 0033988485 scopus 로고    scopus 로고
    • A cysteine-rich motif in poliovirus protein 2C (ATPase) is involved in RNA replication and binds zinc in vitro
    • Pfister T, Jones KW, Wimmer E. A cysteine-rich motif in poliovirus protein 2C (ATPase) is involved in RNA replication and binds zinc in vitro. J Virol 2000; 74:334-43.
    • (2000) J Virol , vol.74 , pp. 334-343
    • Pfister, T.1    Jones, K.W.2    Wimmer, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.