Enterovirus variants in the serum of children at the onset of Type 1 diabetes mellitus

Diabetic Medicine

Volumn 16, Issue 6, 1999, Pages 509-513

  Nairn, C ^a   Galbraith, D N ^a,c   Taylor, Keith W ^b   Clements, G B ^a  

^a GARTNAVEL GENERAL HOSPITAL   (United Kingdom)

^b ROYAL LONDON HOSPITAL   (United Kingdom)

^c Q One Biotech Ltd   (United Kingdom)

Author keywords

Aetiology; Childhood; Enterovirus; Type 1 diabetes mellitus

Indexed keywords

VIRUS RNA;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; DIABETES MELLITUS; ENTEROVIRUS; HUMAN; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; JUVENILE DIABETES MELLITUS; MAJOR CLINICAL STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; VIRUS DETECTION;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; ENTEROVIRUS; HUMANS; INFANT; INFANT, NEWBORN; POLYMERASE CHAIN REACTION; RNA, VIRAL; SEASONS; SEQUENCE ANALYSIS; VARIATION (GENETICS);

EID: 0032751826     PISSN: 07423071     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1464-5491.1999.00098.x     Document Type: Article

References (24)

1. 1 Rewers M, Atkinson M. The possible role of enteroviruses in diabetes mellitus. In Rotbart HA, ed. Human Enterovirus Infections. Washington DC: ASM Press, 1995; 353-385.
2. 2 Graves PM, Norris JM, Pallansch MA, Gerling IC, Rewers M. The role of enteroviral infections in the development of IDDM. Limitations of current approaches. Diabetes 1997; 46: 161-168.
3. 3 Gamble DR, Kinsley ML, Fitzgerald MG, Bolton R, Taylor KW. Viral antibodies in diabetes mellitus. Br Med J 1969; 3: 627-630.
4. 4 Gamble DR, Cumming H. Coxsackie B viruses and juvenile-onset insulin-dependent diabetes. Lancet 1985; ii: 455-456.
5. 5 Uriarte A, Cabrera F, Ventura R, Vargas J. Islet cell antibodies and Echo-4 virus infection, Diabetologia 1987; 30A: 590.
6. 6 Frisk G, Nilsson E, TuvemoT, Friman G, Diderholm H. The possible role of coxsackie A and echoviruses in the pathogenesis of type 1 diabetes mellitus studied by IgM analysis. J Infect 1992; 24: 13-22.
7. 7 Roivainen M, Knip M, Hyöty H, Kulmula P, Hiltunen M, Vahasalo P et al. Several different enterovirus serotypes can be associated with prediabetic autoimmune episodes and onset of overt IDDM. J Med Virol 1998; 56: 74-78.
8. 8 Hyöty H, Hiltunen M, Knip M, Houi T, Akerblom HK. A prospective study of the role of Coxsackie B and other enteroviruses in pathogenesis of IDDM. Diabetes 1995; 44: 652-657.
9. 9 Hiltunen M, Hyöty H, Knip M, Ilonen J, Reijonen H, Väkärdo P et al. ICA seroconversion in children is temporally associated with enterovirus infection. J Infect Dis 1997; 175: 554-560.
10. 10 Dahlquist GC, Ivarsson S, Lindberg B, Forsgren M. Maternal enteroviral infection during pregnancy as a risk factor for childhood IDDM. Diabetes 1995; 44: 408-413.
11. 11 Dahlquist GC, Frisk G, Ivaarson SA, Svanberg L, Forsgen M, Diderholm H. Indications that maternal Coxsackie B infection is a risk factor for childhood onset IDDM. Diabetologia 1995; 38: 1371-1373.
12. 12 Titchcner PA, Jenkins O, Szopa TM, Taylor KW, Almond JW. Complete nucleotide sequence of a beta cell tropic variant of Coxsackie B4. J Med Virol 1995; 42: 369-373.
13. 13 Kang Y, Chatterjee NK, Nodwell MJ, Yoon J-W, Complete nucleotide sequence of Coxsacie B4 virus of human origin that induces diabetes in mice and its comparison with the non-diabetogenic Coxsackie B4 JBV strain. J Med Virol 1994; 44: 353-361.
14. 14 Clements GB, Galbraith DN, Taylor KW. Coxsackie B virus infection and the onset of childhood diabetes. Lancet 1995; 346: 221-223.
15. 15 Andreoletti L, Hober D, Hober-Vandenberghie C, Belaich S, Vantyghem M-C, Lefebvre J et al. Detection of coxsackie B virus RNA sequences in whole blood samples from adult patients at the onset of type 1 diabetes mellitus. J Med Virol 1997; 52: 121-127.
16. 16 Galbraith DN, Nairn C, Clements GB. Phylogenetic analysis of short enteroviral sequences from patients with chronic fatigue syndrome. J Gen Virol 1995; 76: 1701-1707.
17. 17 Hermans A, Gow J, Seleri L. bcr-abl oncogene activation in Philadelphia chromosome positive acute lymphoblastic leukemia. Leukemia 1988; 2: 628-633.
18. 18 Klump WM, Bergmann I, Muller BC, Ameis D, Kandolf R. Complete nudeotide sequence of infectious coxsackie B3 cDNA. J Virol 1990; 64: 1573-1583.
19. 19 Devereux J, Haeberli P, Smithies O. A comprehensive set of sequence analysis programs for the VAX. Nucl Acids Res 1984; 12: 387-395.
20. 20 Hyypia T, Hovi T, Knowles NJ, Stanway G. Classification of enteroviruses based on molecular and biological properties. J Gen Virol 1997; 78: 1-11.
21. 21 Smith CP, Clements GB, Riding M, Collins P, Bottazzo GF, Taylor KW. Simultaneous onset of IDDM in identical infant twins with enterovirus infection. Diabet Med 1998; 15: 515-517.
22. 22 Lönnrot M, Knip M, Roivainen M, Koskela P, Akerblom HK, Hyöty H. Onset of Type 1 diabetes mellitus in infancy after enterovirus infections. Diabet Med 1998; 15: 431-434.
23. 23 Kaufman DL, Erlander MG, Clare-Salzler, Atkinson MA, Maclaren NK, Tobin AJ et al. Autoimmunity to two forms of glutamate decarboxylase in insulin dependent diabetes mellitus. J Clin Invest 1992; 89: 283-292.
24. 24 Horwitz MS, Bradley LM, Harbertson J, Krahl T, Lee J, Sarvetnìck N. Diabetes induced by coxsackie virus: initiation by bystander damage and not molecular mimicry. Nature Med 1998; 4: 781-785.